WO1998052637A1 - Catheter with oblique lumen - Google Patents
Catheter with oblique lumen Download PDFInfo
- Publication number
- WO1998052637A1 WO1998052637A1 PCT/US1998/010581 US9810581W WO9852637A1 WO 1998052637 A1 WO1998052637 A1 WO 1998052637A1 US 9810581 W US9810581 W US 9810581W WO 9852637 A1 WO9852637 A1 WO 9852637A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- probe
- guide wire
- catheter
- lumen
- longitudinal axis
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0067—Catheters; Hollow probes characterised by the distal end, e.g. tips
- A61M25/0068—Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/0105—Steering means as part of the catheter or advancing means; Markers for positioning
- A61M2025/0166—Sensors, electrodes or the like for guiding the catheter to a target zone, e.g. image guided or magnetically guided
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M2025/0177—Introducing, guiding, advancing, emplacing or holding catheters having external means for receiving guide wires, wires or stiffening members, e.g. loops, clamps or lateral tubes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M2025/0183—Rapid exchange or monorail catheters
Definitions
- the present invention relates to catheters and catheterization techniques generally.
- Catheters used in interventional cardiology and other applications are typically guided to a desired location in a human body, most commonly the left ventricle or other chamber of the heart, by first inserting a guide wire to the location and then sliding the catheter over the guide wire.
- the use of the guide wire generally shortens the time required to get the catheter into the ventricle and eases the potentially dangerous passage through the aortic valve, when entering the left ventricle.
- it is also well known in the art to insert a catheter into the heart without the use of a guide wire many cardiologists do not have the requisite level of skill or time to perform this operation, and are deterred by the risk of complications associated with such insertion.
- Catheters for guide wire insertion are normally constructed with an open central lumen, running along the catheter's longitudinal axis, to receive the guide wire. This constructional constraint severely restricts the size and shape of functional elements within the catheter and complicates the catheter's design. Such catheters cannot generally be manipulated within the heart after insertion thereinto. They are therefore substantially restricted to making measurements or performing interventional procedures only at the site within the heart to which the guide wire has been inserted.
- the present invention seeks to provide an improved catheter and catheterization technique which overcome limitations imposed by the prior art.
- a catheter for insertion into the heart has a lumen passing therethrough for receiving a guide wire, wherein the lumen does not substantially coincide with the catheter's longitudinal axis.
- the lumen runs obliquely through a distal portion of the catheter. Because the lumen is situated off the catheter's longitudinal axis, a central portion of the catheter is left clear for placement of functional elements therein, preferably including a tip deflection mechanism for controllably maneuvering the distal portion of the catheter within the heart.
- a guide wire is inserted into the heart, typically into the left ventricle, using catheterization techniques known in the art.
- the catheter is then guided into the heart by sliding the lumen in a distal direction over the guide wire. Once the distal end of the catheter has reached its desired location in the heart, the guide wire is drawn back in a proximal direction, out of the heart, leaving the catheter in place. The distal end of the catheter may then be maneuvered freely within the heart, preferably using the tip deflection mechanism.
- the catheter includes a position sensor within the distal portion thereof.
- the position sensor preferably comprises one or more coils, which generate signals responsive to an externally-applied magnetic field, as described in U.S. Patent 5,391,199 or in PCT publication WO96/05768 and incorporated herein by reference.
- the catheter further includes one or more electrodes on an outer surface of the distal portion, for measuring electrical activity and/or performing surgical procedures, such as electrosurgical ablation of the endocardium.
- the catheter may include other sensors, known in the art, in or adjacent to its distal portion, for example, a pressure sensor or an ultrasound transducer.
- the catheter may include other therapeutic elements, such as a waveguide for conveying radiation to the heart tissue, a channel and/or tool for delivering medication to the tissue, or other elements known in the art.
- catheters in accordance with the principles of the present invention share with guide wire-based catheters known in the art the advantage of rapid, safe and relatively easy insertion into the heart or other body cavity. Unlike catheters known in the art, however, catheters in accordance with the present invention may be maneuvered and navigated freely inside the body. They may thus be used in a range of diagnostic and therapeutic modalities, for example, in mapping of electrophysiological, mechanical, electromechanical and/or hemodynamic aspects of cardiac function.
- a flexible elongate probe having a longitudinal axis and a distal end, the probe enclosing and defining a lumen for receiving and riding over a guide wire, characterized in that the lumen is located other than along the longitudinal axis.
- a catheterization kit including a guide wire and a flexible elongate probe having a longitudinal axis and a distal end, the probe enclosing and defining a lumen for receiving and riding over the guide wire, characterized in that the lumen is located other than along the longitudinal axis.
- the lumen passes through the probe obliquely with respect to the longitudinal axis, most preferably adjacent to the distal end thereof.
- the probe includes a sensor, most preferably a position sensor, adjacent to the distal end.
- the probe includes a deflection mechanism for deflecting the distal end of the probe.
- the probe includes an electrode on an outer surface thereof.
- the lumen passes through the electrode.
- the probe includes a therapeutic device, preferably an ablation electrode, through which the lumen preferably passes.
- the probe is a catheter for insertion into the heart of a subject.
- a catheterization technique including the steps of inserting a guide wire through a body passage and sliding a flexible elongate probe, having a longitudinal axis, along the guide wire, the guide wire passing through a lumen in the probe which is located other than along the longitudinal axis thereof.
- the portion of the guide wire inside the catheter is inclined obliquely with respect to the longitudinal axis.
- the guide wire passes through an electrode fixed to an outer surface of the probe.
- the guide wire is withdrawn, while leaving the probe in place within the body passage, and the probe is navigated within a body cavity communicating with the body passage after withdrawal of the guide wire.
- the body cavity is mapped using the probe.
- a therapeutic procedure is performed within the body cavity using the probe .
- Fig. 1 is a simplified illustration of a catheter and guide wire arrangement constructed and operative in accordance with a preferred embodiment of the present invention
- Fig. 2A is a sectional illustration of the catheter of Fig. 1;
- Fig. 2B is a sectional illustration of a catheter, in accordance with an alternative preferred embodiment of the present invention.
- Figs. 3A-3C are simplified pictorial illustrations of intravascular catheterization using the catheter and guide wire of Fig. 1, in accordance with a preferred embodiment of the present invention.
- Fig. 1 is a simplified pictorial illustration of a catheter 20 with a guide wire 26, in accordance with a preferred embodiment of the present invention.
- Catheter 20 has a lumen 24 for receiving guide wire 26.
- the lumen passes through a distal portion 28 of the catheter obliquely to the catheter's longitudinal axis 22.
- a lumen for receiving the guide wire may be provided at any other suitable location or orientation which is not central to distal portion 28, such that the majority of the portion is available for location therein of functional apparatus for use in therapeutic treatment and/or diagnosis of the patient.
- Such functional apparatus preferably includes elements for navigating catheter 20 within the body, as described below.
- catheter 20 includes a position sensor 30 and a tip deflection mechanism 31.
- Position sensor 30 preferably comprises one or more magnetic-field-responsive coils, as described, for example, in the above-mentioned U.S. patent 5,391,199 or PCT publication WO96/05768.
- Deflection mechanism 31 preferably comprises a resilient, bendable member, operated by a pull-wire 33, as described, for example, in PCT Patent Application PCT/IL98/00099, which is assigned to the assignee of the present patent application and whose disclosure is incorporated herein by reference.
- catheter 20 may include and be navigated within the body by means of any suitable position sensor and/or tip deflection mechanism known in the art.
- Fig. 2A is a schematic, sectional illustration of distal portion 28 of catheter 20.
- catheter 20 preferably has a central bore 32 for accommodating sensor 30, as well as a side bore 34 for accepting deflection mechanism 31. These elements are preferably located proximally to oblique lumen 24.
- catheter 20 includes a ring electrode 29 on an outer surface of distal portion 28.
- the catheter may include a plurality of mutually-spaced electrodes, as are known in the art.
- Fig. 2B is a schematic, sectional illustration of distal portion 28 of catheter 20, in accordance with an alternative preferred embodiment of the present invention.
- the catheter in place of electrode 29, the catheter includes a dome electrode 36 over the distal portion and, preferably, a reference ring electrode 38 proximal thereto.
- the dome electrode provides enhanced functionality and ease of use, particularly in cardiac electrophysiological mapping and in RF ablation therapy.
- Oblique lumen 24 passes through dome electrode 36, which has a suitable opening 37 for this purpose.
- the catheter of Fig. 2B is functionally and structurally similar to that shown in Fig 2A.
- catheter 20 may include functional elements of other types useful in endocardiac diagnostics and therapy, for example, pressure and/or flow sensors, an optical fiber for delivery of laser radiation, or a longitudinal lumen for suction and/or irrigation.
- catheters based on the principles of the present invention may generally include any type of functional or structural element that is used in catheters known in the art.
- Figs. 3A-3C are simplified, schematic drawings showing intravascular catheterization of a subject 40 using catheter 20 and guide wire 26, in accordance with a preferred embodiment of the present invention. As shown in Fig.
- guide wire 26 is inserted percutaneously, preferably via femoral artery 42 of subject 40, and is directed into the subject's heart 44, typically into left ventricle 46, as in conventional intravascular catheterization. Then, as shown in Fig. 3B, catheter 20 is passed along wire 26 into the heart. Alternatively, guide wire 26 may be used to insert catheter 20 into any other desired chamber of the heart, or to another suitable site in the subject's body.
- Fig. 3C guide wire 26 is withdrawn, leaving catheter 20 freely maneuverable within ventricle 46.
- deflection mechanism 31 and sensor 30 a physician can navigate distal portion 28 of catheter 20 to substantially any desired location within the ventricle. This navigation capability is particularly useful in mapping electrical and/or mechanical activity within the heart, as is known in the art and described, for example, in U.S. patent 5,568,809, which is incorporated herein by reference.
- catheter 20 may be used in therapeutic treatment of cardiac arrhythmias, preferably using electrode 29 to ablate areas of the endocardium by applying RF energy thereto, as is known in the art. Most preferably, such ablation is combined with mapping the heart's electrical activity, as described, for example, in U.S. patent 5,391,199, which is incorporated herein by reference.
- catheter 20 may be adapted for use in substantially any diagnostic or therapeutic procedure for which catheters known in the art are used, with the advantage that catheter 20 can generally be inserted into the heart with considerably greater speed, ease and safety than non-wire-guided catheters.
- the catheter may include an optical waveguide, coupled to a source of laser energy at the catheter' s proximal end, for use in percutaneous myocardial revascularization (PMR) therapy, as described in PCT patent application PCT/IL97/00011, filed January 14, 1997, which is incorporated herein by reference, or as is otherwise known in the art.
- PMR percutaneous myocardial revascularization
- catheters, endoscopes and other types of flexible medical probes may be produced and operated in accordance with the principles of the present invention for insertion into substantially any part of the heart, vasculature and other body cavities.
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU75943/98A AU7594398A (en) | 1997-05-23 | 1998-05-22 | Catheter with oblique lumen |
EP98923717A EP0929338A1 (en) | 1997-05-23 | 1998-05-22 | Catheter with oblique lumen |
IL12811698A IL128116A0 (en) | 1997-05-23 | 1998-05-22 | Catheter with oblique lumen |
JP55072198A JP2002515813A (en) | 1997-05-23 | 1998-05-22 | Catheter with obliquely extending lumen |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4751297P | 1997-05-23 | 1997-05-23 | |
US60/047,512 | 1997-05-23 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1998052637A1 true WO1998052637A1 (en) | 1998-11-26 |
Family
ID=21949393
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1998/010581 WO1998052637A1 (en) | 1997-05-23 | 1998-05-22 | Catheter with oblique lumen |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0929338A1 (en) |
JP (1) | JP2002515813A (en) |
AU (1) | AU7594398A (en) |
WO (1) | WO1998052637A1 (en) |
Cited By (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2341102A (en) * | 1998-09-05 | 2000-03-08 | Smiths Industries Plc | A tracheostomy tube obturator |
US7141050B2 (en) | 2002-10-18 | 2006-11-28 | Wilson-Cook Medical Inc. | Catheter with a plurality of wire guide access parts |
US7771717B2 (en) | 1995-02-10 | 2010-08-10 | Purdue Research Foundation | Enhanced submucosal tissue graft constructs |
US7776596B2 (en) | 2002-05-02 | 2010-08-17 | Purdue Research Foundation | Vascularization enhanced graft constructs |
US7795022B2 (en) * | 2002-05-02 | 2010-09-14 | Purdue Research Foundation | Vascularization enhanced graft constructs |
US7815686B2 (en) | 2002-05-02 | 2010-10-19 | Purdue Research Foundation | Vascularization enhanced graft constructs |
CN101947346A (en) * | 2010-09-10 | 2011-01-19 | 张烨 | Catheter |
US8690819B2 (en) | 2002-08-26 | 2014-04-08 | Flowcardia, Inc. | Ultrasound catheter for disrupting blood vessel obstructions |
US8862204B2 (en) | 2002-11-18 | 2014-10-14 | Mediguide Ltd. | Reducing mechanical stress on conductors and connection points in a position determinable interventional medical device |
US8888773B2 (en) | 2012-05-11 | 2014-11-18 | Medtronic Ardian Luxembourg S.A.R.L. | Multi-electrode catheter assemblies for renal neuromodulation and associated systems and methods |
US8956375B2 (en) | 2002-08-26 | 2015-02-17 | Flowcardia, Inc. | Ultrasound catheter devices and methods |
US8956352B2 (en) | 2010-10-25 | 2015-02-17 | Medtronic Ardian Luxembourg S.A.R.L. | Catheter apparatuses having multi-electrode arrays for renal neuromodulation and associated systems and methods |
US8961423B2 (en) | 2003-02-26 | 2015-02-24 | Flowcardia, Inc. | Ultrasound catheter apparatus |
US9084610B2 (en) | 2010-10-21 | 2015-07-21 | Medtronic Ardian Luxembourg S.A.R.L. | Catheter apparatuses, systems, and methods for renal neuromodulation |
US9265520B2 (en) | 2002-08-02 | 2016-02-23 | Flowcardia, Inc. | Therapeutic ultrasound system |
US9282984B2 (en) | 2006-04-05 | 2016-03-15 | Flowcardia, Inc. | Therapeutic ultrasound system |
US9381027B2 (en) | 2002-08-26 | 2016-07-05 | Flowcardia, Inc. | Steerable ultrasound catheter |
US9402646B2 (en) | 2009-06-12 | 2016-08-02 | Flowcardia, Inc. | Device and method for vascular re-entry |
US9433433B2 (en) | 2003-09-19 | 2016-09-06 | Flowcardia, Inc. | Connector for securing ultrasound catheter to transducer |
US9629643B2 (en) | 2006-11-07 | 2017-04-25 | Flowcardia, Inc. | Ultrasound catheter having improved distal end |
US10004520B2 (en) | 2004-08-26 | 2018-06-26 | Flowcardia, Inc. | Ultrasound catheter devices and methods |
US10166069B2 (en) | 2014-01-27 | 2019-01-01 | Medtronic Ardian Luxembourg S.A.R.L. | Neuromodulation catheters having jacketed neuromodulation elements and related devices, systems, and methods |
US10188829B2 (en) | 2012-10-22 | 2019-01-29 | Medtronic Ardian Luxembourg S.A.R.L. | Catheters with enhanced flexibility and associated devices, systems, and methods |
US10285719B2 (en) | 2005-01-20 | 2019-05-14 | Flowcardia, Inc. | Vibrational catheter devices and methods for making same |
US10357263B2 (en) | 2012-01-18 | 2019-07-23 | C. R. Bard, Inc. | Vascular re-entry device |
US10548663B2 (en) | 2013-05-18 | 2020-02-04 | Medtronic Ardian Luxembourg S.A.R.L. | Neuromodulation catheters with shafts for enhanced flexibility and control and associated devices, systems, and methods |
US10582983B2 (en) | 2017-02-06 | 2020-03-10 | C. R. Bard, Inc. | Ultrasonic endovascular catheter with a controllable sheath |
US10736690B2 (en) | 2014-04-24 | 2020-08-11 | Medtronic Ardian Luxembourg S.A.R.L. | Neuromodulation catheters and associated systems and methods |
US10758256B2 (en) | 2016-12-22 | 2020-09-01 | C. R. Bard, Inc. | Ultrasonic endovascular catheter |
US10835267B2 (en) | 2002-08-02 | 2020-11-17 | Flowcardia, Inc. | Ultrasound catheter having protective feature against breakage |
US11344750B2 (en) | 2012-08-02 | 2022-05-31 | Flowcardia, Inc. | Ultrasound catheter system |
US11478574B2 (en) | 2013-10-16 | 2022-10-25 | Purdue Research Foundation | Collagen compositions and methods of use |
US11596726B2 (en) | 2016-12-17 | 2023-03-07 | C.R. Bard, Inc. | Ultrasound devices for removing clots from catheters and related methods |
US11633206B2 (en) | 2016-11-23 | 2023-04-25 | C.R. Bard, Inc. | Catheter with retractable sheath and methods thereof |
US11739291B2 (en) | 2017-04-25 | 2023-08-29 | Purdue Research Foundation | 3-dimensional (3D) tissue-engineered muscle for tissue restoration |
US11919941B2 (en) | 2015-04-21 | 2024-03-05 | Purdue Research Foundation | Cell-collagen-silica composites and methods of making and using the same |
Families Citing this family (2)
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JP2006516203A (en) * | 2002-11-18 | 2006-06-29 | メディガイド リミテッド | Method and system for mounting an MPS sensor on a catheter |
JP5326313B2 (en) * | 2008-03-21 | 2013-10-30 | ニプロ株式会社 | Thrombus capture catheter |
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WO1993015790A1 (en) * | 1992-02-14 | 1993-08-19 | Boaz Avitall | Biplanar deflectable catheter for arrhythmogenic tissue ablation |
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-
1998
- 1998-05-22 WO PCT/US1998/010581 patent/WO1998052637A1/en not_active Application Discontinuation
- 1998-05-22 JP JP55072198A patent/JP2002515813A/en active Pending
- 1998-05-22 AU AU75943/98A patent/AU7594398A/en not_active Abandoned
- 1998-05-22 EP EP98923717A patent/EP0929338A1/en not_active Withdrawn
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Cited By (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7771717B2 (en) | 1995-02-10 | 2010-08-10 | Purdue Research Foundation | Enhanced submucosal tissue graft constructs |
GB2341102A (en) * | 1998-09-05 | 2000-03-08 | Smiths Industries Plc | A tracheostomy tube obturator |
FR2782926A1 (en) * | 1998-09-05 | 2000-03-10 | Smiths Industries Plc | INTRODUCER FOR AN ASSEMBLY COMPRISING A MEDICAL TUBE |
US6286509B1 (en) | 1998-09-05 | 2001-09-11 | Smiths Group Plc | Introducers and tube assemblies |
GB2341102B (en) * | 1998-09-05 | 2003-05-28 | Smiths Industries Plc | Introducers and tube assemblies |
US7776596B2 (en) | 2002-05-02 | 2010-08-17 | Purdue Research Foundation | Vascularization enhanced graft constructs |
US7795022B2 (en) * | 2002-05-02 | 2010-09-14 | Purdue Research Foundation | Vascularization enhanced graft constructs |
US7815686B2 (en) | 2002-05-02 | 2010-10-19 | Purdue Research Foundation | Vascularization enhanced graft constructs |
US10722262B2 (en) | 2002-08-02 | 2020-07-28 | Flowcardia, Inc. | Therapeutic ultrasound system |
US10835267B2 (en) | 2002-08-02 | 2020-11-17 | Flowcardia, Inc. | Ultrasound catheter having protective feature against breakage |
US10111680B2 (en) | 2002-08-02 | 2018-10-30 | Flowcardia, Inc. | Therapeutic ultrasound system |
US9265520B2 (en) | 2002-08-02 | 2016-02-23 | Flowcardia, Inc. | Therapeutic ultrasound system |
US9381027B2 (en) | 2002-08-26 | 2016-07-05 | Flowcardia, Inc. | Steerable ultrasound catheter |
US8690819B2 (en) | 2002-08-26 | 2014-04-08 | Flowcardia, Inc. | Ultrasound catheter for disrupting blood vessel obstructions |
US8956375B2 (en) | 2002-08-26 | 2015-02-17 | Flowcardia, Inc. | Ultrasound catheter devices and methods |
US10285727B2 (en) | 2002-08-26 | 2019-05-14 | Flowcardia, Inc. | Steerable ultrasound catheter |
US10376272B2 (en) | 2002-08-26 | 2019-08-13 | Flowcardia, Inc. | Ultrasound catheter for disrupting blood vessel obstructions |
US9421024B2 (en) | 2002-08-26 | 2016-08-23 | Flowcardia, Inc. | Steerable ultrasound catheter |
US7141050B2 (en) | 2002-10-18 | 2006-11-28 | Wilson-Cook Medical Inc. | Catheter with a plurality of wire guide access parts |
US10493235B2 (en) | 2002-11-18 | 2019-12-03 | St. Jude Medical International Holding S.àr.l. | Reducing mechanical stress on conductors and connection points in a position determinable interventional medical device |
US9375549B2 (en) | 2002-11-18 | 2016-06-28 | Mediguide Ltd. | Reducing mechanical stress on conductors and connection points in a position determinable interventional medical device |
US8862204B2 (en) | 2002-11-18 | 2014-10-14 | Mediguide Ltd. | Reducing mechanical stress on conductors and connection points in a position determinable interventional medical device |
US10130380B2 (en) | 2003-02-26 | 2018-11-20 | Flowcardia, Inc. | Ultrasound catheter apparatus |
US8961423B2 (en) | 2003-02-26 | 2015-02-24 | Flowcardia, Inc. | Ultrasound catheter apparatus |
US11103261B2 (en) | 2003-02-26 | 2021-08-31 | C.R. Bard, Inc. | Ultrasound catheter apparatus |
US10349964B2 (en) | 2003-09-19 | 2019-07-16 | Flowcardia, Inc. | Connector for securing ultrasound catheter to transducer |
US11426189B2 (en) | 2003-09-19 | 2022-08-30 | Flowcardia, Inc. | Connector for securing ultrasound catheter to transducer |
US9433433B2 (en) | 2003-09-19 | 2016-09-06 | Flowcardia, Inc. | Connector for securing ultrasound catheter to transducer |
US11109884B2 (en) | 2003-11-24 | 2021-09-07 | Flowcardia, Inc. | Steerable ultrasound catheter |
US10004520B2 (en) | 2004-08-26 | 2018-06-26 | Flowcardia, Inc. | Ultrasound catheter devices and methods |
US10682151B2 (en) | 2004-08-26 | 2020-06-16 | Flowcardia, Inc. | Ultrasound catheter devices and methods |
US11510690B2 (en) | 2005-01-20 | 2022-11-29 | Flowcardia, Inc. | Vibrational catheter devices and methods for making same |
US10285719B2 (en) | 2005-01-20 | 2019-05-14 | Flowcardia, Inc. | Vibrational catheter devices and methods for making same |
US9282984B2 (en) | 2006-04-05 | 2016-03-15 | Flowcardia, Inc. | Therapeutic ultrasound system |
US11229772B2 (en) | 2006-11-07 | 2022-01-25 | Flowcardia, Inc. | Ultrasound catheter having improved distal end |
US9629643B2 (en) | 2006-11-07 | 2017-04-25 | Flowcardia, Inc. | Ultrasound catheter having improved distal end |
US10537712B2 (en) | 2006-11-07 | 2020-01-21 | Flowcardia, Inc. | Ultrasound catheter having improved distal end |
US9402646B2 (en) | 2009-06-12 | 2016-08-02 | Flowcardia, Inc. | Device and method for vascular re-entry |
CN101947346B (en) * | 2010-09-10 | 2012-02-15 | 张烨 | Catheter |
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Also Published As
Publication number | Publication date |
---|---|
JP2002515813A (en) | 2002-05-28 |
AU7594398A (en) | 1998-12-11 |
EP0929338A1 (en) | 1999-07-21 |
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