WO1998055607A3 - Tumor targeted vector - Google Patents
Tumor targeted vector Download PDFInfo
- Publication number
- WO1998055607A3 WO1998055607A3 PCT/GB1998/001627 GB9801627W WO9855607A3 WO 1998055607 A3 WO1998055607 A3 WO 1998055607A3 GB 9801627 W GB9801627 W GB 9801627W WO 9855607 A3 WO9855607 A3 WO 9855607A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- tumor targeted
- targeted vector
- vector
- noi
- poi
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/485—Epidermal growth factor [EGF] (urogastrone)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70532—B7 molecules, e.g. CD80, CD86
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/027—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus
Abstract
Priority Applications (17)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR19997011207A KR20010013219A (en) | 1997-06-04 | 1998-06-04 | Vector |
AU77801/98A AU747602B2 (en) | 1997-06-04 | 1998-06-04 | Vector |
DE69841204T DE69841204D1 (en) | 1997-06-04 | 1998-06-04 | Tumor targeted vector |
AT98925827T ATE444358T1 (en) | 1997-06-04 | 1998-06-04 | TUMOR TARGETED VECTOR |
IL13259698A IL132596A0 (en) | 1997-06-04 | 1998-06-04 | Vector |
JP50185899A JP2002507117A (en) | 1997-06-04 | 1998-06-04 | vector |
US09/445,375 US6852703B1 (en) | 1997-06-04 | 1998-06-04 | Tumor targeted vector |
NZ500633A NZ500633A (en) | 1997-06-04 | 1998-06-04 | Vector |
DK98925827.2T DK1012259T3 (en) | 1997-06-04 | 1998-06-04 | Tumor-directed vector |
EP98925827A EP1012259B1 (en) | 1997-06-04 | 1998-06-04 | Tumor targeted vector |
CA002292760A CA2292760A1 (en) | 1997-06-04 | 1998-06-04 | Vector |
NO995901A NO995901L (en) | 1997-06-04 | 1999-12-02 | Vector |
US10/104,522 US7531648B2 (en) | 1997-06-04 | 2002-03-22 | Vector encoding an antibody that binds 5T4 antigen |
US11/380,188 US7718627B2 (en) | 1997-06-04 | 2006-04-25 | Vector |
US11/834,649 US20080175819A1 (en) | 1997-06-04 | 2007-08-06 | Vector system |
US12/186,839 US20090017532A1 (en) | 1997-06-04 | 2008-08-06 | Vector |
US12/714,264 US8084249B2 (en) | 1997-06-04 | 2010-02-26 | Vector |
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9711579.4 | 1997-06-04 | ||
GBGB9711579.4A GB9711579D0 (en) | 1997-06-04 | 1997-06-04 | Therapeutic genes |
GB9713150.2 | 1997-06-20 | ||
GBGB9713150.2A GB9713150D0 (en) | 1997-06-20 | 1997-06-20 | Fusion proteins |
GBGB9714230.1A GB9714230D0 (en) | 1997-07-04 | 1997-07-04 | Therapeutic genes |
GB9714230.1 | 1997-07-04 |
Related Child Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09/445,375 A-371-Of-International US6852703B1 (en) | 1997-06-04 | 1998-06-04 | Tumor targeted vector |
US09445375 A-371-Of-International | 1998-06-04 | ||
PCT/GB2000/004317 Continuation-In-Part WO2001036486A2 (en) | 1997-06-04 | 2000-11-13 | Scfv antibodies against disease associated molecules |
US10/104,522 Division US7531648B2 (en) | 1997-06-04 | 2002-03-22 | Vector encoding an antibody that binds 5T4 antigen |
US10/787,881 Division US20050032216A1 (en) | 1997-06-04 | 2004-02-25 | Vector |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1998055607A2 WO1998055607A2 (en) | 1998-12-10 |
WO1998055607A3 true WO1998055607A3 (en) | 1999-03-04 |
Family
ID=27268875
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB1998/001627 WO1998055607A2 (en) | 1997-06-04 | 1998-06-04 | Tumor targeted vector |
Country Status (16)
Country | Link |
---|---|
US (6) | US6852703B1 (en) |
EP (2) | EP1717248A1 (en) |
JP (3) | JP2002507117A (en) |
CN (1) | CN1224712C (en) |
AT (1) | ATE444358T1 (en) |
AU (1) | AU747602B2 (en) |
CA (1) | CA2292760A1 (en) |
CY (1) | CY1109686T1 (en) |
DE (1) | DE69841204D1 (en) |
DK (1) | DK1012259T3 (en) |
ES (1) | ES2332435T3 (en) |
IL (1) | IL132596A0 (en) |
NO (1) | NO995901L (en) |
NZ (1) | NZ500633A (en) |
PT (1) | PT1012259E (en) |
WO (1) | WO1998055607A2 (en) |
Families Citing this family (58)
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GB9709421D0 (en) | 1997-05-10 | 1997-07-02 | Zeneca Ltd | Chemical compounds |
ES2332435T3 (en) * | 1997-06-04 | 2010-02-04 | Oxford Biomedica (Uk) Limited | VECTOR DIRECTED TO TUMORS. |
US7276488B2 (en) * | 1997-06-04 | 2007-10-02 | Oxford Biomedica (Uk) Limited | Vector system |
US7635687B2 (en) * | 1997-06-04 | 2009-12-22 | Oxford Biomedica (Uk) Limited | Vector system |
GB2371803A (en) * | 1999-11-18 | 2002-08-07 | Oxford Biomedica Ltd | Antibodies |
ATE411342T1 (en) * | 1999-11-18 | 2008-10-15 | Oxford Biomedica Ltd | SCFV ANTIBODIES AGAINST DISEASE-ASSOCIATED MOLECULES |
JP2003515323A (en) * | 1999-11-18 | 2003-05-07 | オックスフォード バイオメディカ(ユーケイ)リミテッド | Body |
US7575924B2 (en) | 2000-11-13 | 2009-08-18 | Research Development Foundation | Methods and compositions relating to improved lentiviral vectors and their applications |
US7629153B2 (en) * | 2001-08-02 | 2009-12-08 | Research Development Foundation | Methods and compositions relating to improved lentiviral vector production systems |
KR20040054699A (en) * | 2001-10-02 | 2004-06-25 | 엥스띠뛰 끌레이톤 드 라 러쉐르쉬 | Methods and compositions relating to restricted expression lentiviral vectors and their applications |
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-
1998
- 1998-06-04 ES ES98925827T patent/ES2332435T3/en not_active Expired - Lifetime
- 1998-06-04 DE DE69841204T patent/DE69841204D1/en not_active Expired - Lifetime
- 1998-06-04 DK DK98925827.2T patent/DK1012259T3/en active
- 1998-06-04 EP EP05025532A patent/EP1717248A1/en not_active Withdrawn
- 1998-06-04 NZ NZ500633A patent/NZ500633A/en not_active IP Right Cessation
- 1998-06-04 CA CA002292760A patent/CA2292760A1/en not_active Abandoned
- 1998-06-04 WO PCT/GB1998/001627 patent/WO1998055607A2/en not_active Application Discontinuation
- 1998-06-04 CN CNB988055295A patent/CN1224712C/en not_active Expired - Lifetime
- 1998-06-04 AU AU77801/98A patent/AU747602B2/en not_active Expired
- 1998-06-04 US US09/445,375 patent/US6852703B1/en not_active Expired - Fee Related
- 1998-06-04 EP EP98925827A patent/EP1012259B1/en not_active Revoked
- 1998-06-04 JP JP50185899A patent/JP2002507117A/en active Pending
- 1998-06-04 PT PT98925827T patent/PT1012259E/en unknown
- 1998-06-04 IL IL13259698A patent/IL132596A0/en unknown
- 1998-06-04 AT AT98925827T patent/ATE444358T1/en active
-
1999
- 1999-12-02 NO NO995901A patent/NO995901L/en not_active Application Discontinuation
-
2002
- 2002-03-22 US US10/104,522 patent/US7531648B2/en not_active Expired - Fee Related
-
2004
- 2004-02-25 US US10/787,881 patent/US20050032216A1/en not_active Abandoned
-
2006
- 2006-04-25 US US11/380,188 patent/US7718627B2/en not_active Expired - Fee Related
-
2008
- 2008-08-06 US US12/186,839 patent/US20090017532A1/en not_active Abandoned
-
2009
- 2009-04-01 JP JP2009089505A patent/JP2009153524A/en not_active Withdrawn
- 2009-11-26 CY CY20091101240T patent/CY1109686T1/en unknown
-
2010
- 2010-02-26 US US12/714,264 patent/US8084249B2/en not_active Expired - Fee Related
- 2010-08-09 JP JP2010178576A patent/JP2011000122A/en active Pending
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US20050032216A1 (en) | 2005-02-10 |
IL132596A0 (en) | 2001-03-19 |
EP1012259B1 (en) | 2009-09-30 |
DK1012259T3 (en) | 2010-01-18 |
US7531648B2 (en) | 2009-05-12 |
US7718627B2 (en) | 2010-05-18 |
ES2332435T3 (en) | 2010-02-04 |
EP1012259A2 (en) | 2000-06-28 |
US20030018004A1 (en) | 2003-01-23 |
AU7780198A (en) | 1998-12-21 |
CY1109686T1 (en) | 2014-08-13 |
ATE444358T1 (en) | 2009-10-15 |
US20090017532A1 (en) | 2009-01-15 |
CN1224712C (en) | 2005-10-26 |
NO995901D0 (en) | 1999-12-02 |
US8084249B2 (en) | 2011-12-27 |
NZ500633A (en) | 2002-10-25 |
US20110065173A1 (en) | 2011-03-17 |
US20060286634A1 (en) | 2006-12-21 |
AU747602B2 (en) | 2002-05-16 |
EP1717248A1 (en) | 2006-11-02 |
DE69841204D1 (en) | 2009-11-12 |
NO995901L (en) | 2000-02-04 |
US6852703B1 (en) | 2005-02-08 |
PT1012259E (en) | 2009-11-06 |
JP2009153524A (en) | 2009-07-16 |
CA2292760A1 (en) | 1998-12-10 |
JP2002507117A (en) | 2002-03-05 |
CN1258319A (en) | 2000-06-28 |
JP2011000122A (en) | 2011-01-06 |
WO1998055607A2 (en) | 1998-12-10 |
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