WO1999004828A3 - Use of hyaluronic acid derivatives in the preparation of biomaterials - Google Patents
Use of hyaluronic acid derivatives in the preparation of biomaterials Download PDFInfo
- Publication number
- WO1999004828A3 WO1999004828A3 PCT/EP1998/004716 EP9804716W WO9904828A3 WO 1999004828 A3 WO1999004828 A3 WO 1999004828A3 EP 9804716 W EP9804716 W EP 9804716W WO 9904828 A3 WO9904828 A3 WO 9904828A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- preparation
- biomaterials
- hyaluronic acid
- acid derivatives
- formation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/041—Mixtures of macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/042—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/418—Agents promoting blood coagulation, blood-clotting agents, embolising agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/04—Materials for stopping bleeding
Abstract
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000503879A JP4417547B2 (en) | 1997-07-28 | 1998-07-28 | Use of hyaluronic acid derivatives in the manufacture of biocompatible materials having physical hemostatic and embolic activity and prophylactic activity for adhesion formation after anastomosis |
CA002298733A CA2298733C (en) | 1997-07-28 | 1998-07-28 | Hyaluronic acid derivatives for the preparation of haemostatic biomaterials for use following anastomosis |
AT98945104T ATE311208T1 (en) | 1997-07-28 | 1998-07-28 | USE OF HYALUONIC ACID DERIVATIVES FOR PRODUCING BIOMATERIAL |
DE69832616T DE69832616T2 (en) | 1997-07-28 | 1998-07-28 | USE OF HYALUONIC ACID DERIVATIVES FOR THE MANUFACTURE OF BIOMATERIAL |
EP98945104A EP0999859B1 (en) | 1997-07-28 | 1998-07-28 | Use of hyaluronic acid derivatives in the preparation of biomaterials |
AU92555/98A AU749627B2 (en) | 1997-07-28 | 1998-07-28 | Use of hyaluronic acid derivatives in the preparation of biomaterials with a physical haemostatic and plugging activity and a preventive activity in the formation of adhesions following anastomosis |
IL13414098A IL134140A0 (en) | 1997-07-28 | 1998-07-28 | Use of hyaluronic acid derivatives in the preparation of biomaterials with a physical haemostatic and plugging activity and a preventive activity in the formation of adhesion following anastomosis |
IL134140A IL134140A (en) | 1997-07-28 | 2000-01-20 | Use of hyaluronic acid derivatives in the preparation of biomaterials with a physical haemostatic and plugging activity and a preventive activity in the formation of adhesions following anastomosis |
HK00107189A HK1028210A1 (en) | 1997-07-28 | 2000-11-10 | Use of hyaluronic acid derivatives in the preparation of biomaterials |
US10/139,878 US7202230B2 (en) | 1997-07-28 | 2002-05-07 | Use of hyaluronic acid derivatives in the preparation of biomaterials with a physical haemostatic and plugging activity |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITPD97A000170 | 1997-07-28 | ||
IT97PD000170A IT1294797B1 (en) | 1997-07-28 | 1997-07-28 | USE OF HYALURONIC ACID DERIVATIVES IN THE PREPARATION OF BIOMATERIALS WITH PHYSICAL AND BUFFERING HEMOSTATIC ACTIVITIES |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US49394300A Continuation-In-Part | 1997-07-28 | 2000-01-28 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1999004828A2 WO1999004828A2 (en) | 1999-02-04 |
WO1999004828A3 true WO1999004828A3 (en) | 1999-06-10 |
Family
ID=11391877
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP1998/004716 WO1999004828A2 (en) | 1997-07-28 | 1998-07-28 | Use of hyaluronic acid derivatives in the preparation of biomaterials |
Country Status (13)
Country | Link |
---|---|
US (1) | US7202230B2 (en) |
EP (1) | EP0999859B1 (en) |
JP (1) | JP4417547B2 (en) |
AT (1) | ATE311208T1 (en) |
AU (1) | AU749627B2 (en) |
CA (1) | CA2298733C (en) |
DE (1) | DE69832616T2 (en) |
DK (1) | DK0999859T3 (en) |
ES (1) | ES2253827T3 (en) |
HK (1) | HK1028210A1 (en) |
IL (2) | IL134140A0 (en) |
IT (1) | IT1294797B1 (en) |
WO (1) | WO1999004828A2 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9265858B2 (en) | 2012-06-12 | 2016-02-23 | Ferrosan Medical Devices A/S | Dry haemostatic composition |
US9533069B2 (en) | 2008-02-29 | 2017-01-03 | Ferrosan Medical Devices A/S | Device for promotion of hemostasis and/or wound healing |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1306679B1 (en) * | 1999-06-29 | 2001-10-02 | Fidia Advanced Biopolymers Srl | USE OF HYALURONIC ACID DERIVATIVES FOR THE PREPARATION OF PHARMACEUTICAL AND BIOMATERIAL COMPOSITIONS FOR THE PREVENTION OF |
WO2001097826A2 (en) * | 2000-06-16 | 2001-12-27 | University Of Medicine And Dentistry Of New Jersey | Hemostatic compositions, devices and methods |
US7094428B2 (en) | 2000-06-16 | 2006-08-22 | The University Of Medicine And Dentistry Of New Jersey | Hemostatic compositions, devices and methods |
US6235796B1 (en) * | 2000-06-26 | 2001-05-22 | Sarfaraz K. Niazi | Use of fluorocarbons for the prevention of surgical adhesions |
JP4500263B2 (en) * | 2003-07-28 | 2010-07-14 | 帝人株式会社 | Temperature-responsive hydrogel |
DE10349722A1 (en) * | 2003-10-23 | 2005-06-16 | Beschorner, Katharina, Dr. | Composition for arthritis / arthritis treatment, in particular of joints |
WO2006005340A1 (en) * | 2004-07-09 | 2006-01-19 | Ferrosan A/S | Haemostatic composition comprising hyaluronic acid |
ITPD20040245A1 (en) * | 2004-10-08 | 2005-01-08 | Fidia Advanced Biopolymers Srl | BIOMATERIALS MADE UP OF HYALURONIC ACID, SULFATE AND GELL, USABLE IN THE PREVENTION OF SPINAL ADHESIONS |
ES2313445T3 (en) * | 2004-12-14 | 2009-03-01 | Fidia Advanced Biopolymers S.R.L. | PROCEDURE FOR THE PREPARATION OF BI- AND THREE-DIMENSIONAL POLYMER ARMS. |
ITPD20040312A1 (en) * | 2004-12-15 | 2005-03-15 | Fidia Advanced Biopolymers Srl | PROSTHESIS AND SUPPORT FOR REPLACEMENT, REPAIR, REGENERATION OF THE MENISCUS |
ITPD20050206A1 (en) | 2005-07-07 | 2007-01-08 | Fidia Advanced Biopolymers Srl | BIOMATERIALS IN THE FORM OF FIBER TO BE USED AS MEDICAL DEVICES IN THE TREATMENT OF WOUNDS AND THEIR PROCESSES OF PRODUCTION |
ITMI20051415A1 (en) * | 2005-07-22 | 2007-01-23 | Fidia Advanced Biopolymers Srl | BIOMATERIALS BASED ON SALT-MADE CORBOSSIMETHYLCELLULOSE WITH ZINC ASSOCIATED WITH IALURONIC ACID DERIVATIVES TO BE USED AS MEDICAL DEVICES WITH ANTIMICROBIAL AND ANTIFUNGAL ACTIVITY AND THEIR PRODUCTION PROCESS |
WO2007103993A2 (en) * | 2006-03-07 | 2007-09-13 | Axle International | Bioactive scaffold for therapeutic and adhesion prevention applications |
ITPD20060219A1 (en) | 2006-05-31 | 2007-12-01 | Fidia Farmaceutici | PHARMACEUTICAL COMPOSITIONS CONTAINING HYALURONIC ACID SULFATED IN THE TREATMENT OF OSTEOARTHROSIS |
US8343942B2 (en) | 2008-04-04 | 2013-01-01 | University Of Utah Research Foundation | Methods for treating interstitial cystitis |
AU2009231634B2 (en) | 2008-04-04 | 2014-05-15 | University Of Utah Research Foundation | Alkylated semi-synthetic glycosaminoglycosan ethers, and methods for making and using thereof |
ES2829971T3 (en) * | 2008-09-02 | 2021-06-02 | Tautona Group Lp | Hyaluronic acid threads and / or derivatives thereof, methods to manufacture them and uses thereof |
TWI458833B (en) | 2010-05-11 | 2014-11-01 | Univ China Medical | Nanometal dispersion and method for preparing the same |
CA2830933A1 (en) | 2011-03-23 | 2012-09-27 | University Of Utah Research Foundation | Methods for treating or preventing urological inflammation |
EP2822474B1 (en) | 2012-03-06 | 2018-05-02 | Ferrosan Medical Devices A/S | Pressurized container containing haemostatic paste |
EP3010419B1 (en) | 2013-06-21 | 2020-05-20 | Ferrosan Medical Devices A/S | Vacuum expanded dry composition and syringe for retaining same |
AU2014361291B2 (en) | 2013-12-11 | 2017-11-30 | Ferrosan Medical Devices A/S | Dry composition comprising an extrusion enhancer |
PT3226905T (en) * | 2014-02-27 | 2022-01-19 | Synartro Ab | Hyaluronan conjugates with pharmaceutically active substances, methods and compositions |
JP6726852B2 (en) | 2014-10-13 | 2020-07-22 | フェッローサン メディカル ディバイス エー/エス | Dry composition for use in hemostasis and wound healing |
JP6747650B2 (en) | 2014-12-24 | 2020-08-26 | フェロサン メディカル デバイシーズ エイ/エス | Syringe for holding and mixing the first substance and the second substance |
JP6747651B2 (en) | 2015-07-03 | 2020-08-26 | フェロサン メディカル デバイシーズ エイ/エス | Syringe for holding vacuum in storage and for mixing two components |
KR20180027126A (en) * | 2016-09-06 | 2018-03-14 | (주)한국비엠아이 | Hemostatic Composition comprising cross-linked hyaluronic acid derivative matrix |
US11337994B2 (en) | 2016-09-15 | 2022-05-24 | University Of Utah Research Foundation | In situ gelling compositions for the treatment or prevention of inflammation and tissue damage |
EP4321182A2 (en) | 2018-05-09 | 2024-02-14 | Ferrosan Medical Devices A/S | Method for preparing a haemostatic composition |
KR101980063B1 (en) * | 2019-01-25 | 2019-05-17 | 주식회사 휴메딕스 | Sponge Type Biodegradable Hemostatic Compositions Containing Hyaluronic Acid |
CN113754795B (en) * | 2021-10-19 | 2023-03-10 | 澳门大学 | Sulfonated hyaluronic acid compound, preparation method and application thereof |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0216453A2 (en) * | 1985-07-08 | 1987-04-01 | FIDIA S.p.A. | Esters of hyaluronic acid and their salts. |
EP0341745A1 (en) * | 1988-05-13 | 1989-11-15 | FIDIA S.p.A. | Crosslinked carboxy polysaccharides |
WO1990014110A1 (en) * | 1989-05-16 | 1990-11-29 | Jean Vilain | Improvements in or relating to pharmaceutical preparations |
WO1992019802A1 (en) * | 1991-05-01 | 1992-11-12 | C.V. Laboratories Limited | Alginate fabric, its use in wound dressings and surgical haemostats and a process for its manufacture |
WO1995025751A1 (en) * | 1994-03-23 | 1995-09-28 | Fidia Advanced Biopolymers Srl | Novel heparin-like sulfated polysaccharides |
WO1996035720A1 (en) * | 1995-05-10 | 1996-11-14 | Fidia Advanced Biopolymers S.R.L. | Heavy metal salts of succinic acid hemiesters with hyaluronic acid, or hyaluronic acid esters, a process for their preparation, and relative pharmaceutical compositions |
WO1997002845A1 (en) * | 1995-07-13 | 1997-01-30 | Bristol-Myers Squibb Company | A film for topical use in the treatment of wounds |
WO1997007833A2 (en) * | 1995-08-29 | 1997-03-06 | Fidia Advanced Biopolymers, S.R.L. | Biomaterials for preventing post-surgical adhesions comprised of hyaluronic acid derivatives |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5202431A (en) | 1985-07-08 | 1993-04-13 | Fidia, S.P.A. | Partial esters of hyaluronic acid |
IT1203814B (en) | 1986-06-30 | 1989-02-23 | Fidia Farmaceutici | ESTERS OF ALGINIC ACID |
IT1198449B (en) | 1986-10-13 | 1988-12-21 | F I D I Farmaceutici Italiani | ESTERS OF POLYVALENT ALCOHOLS OF HYALURONIC ACID |
US6174999B1 (en) * | 1987-09-18 | 2001-01-16 | Genzyme Corporation | Water insoluble derivatives of polyanionic polysaccharides |
IT1247157B (en) | 1991-02-11 | 1994-12-12 | Fidia Spa | BIODEGRADABLE AND BIOABSORBABLE GUIDE CHANNELS TO BE USED FOR NERVE REGENERATION. |
DE69210879T2 (en) | 1991-02-11 | 1996-10-17 | Fidia Spa | Gellanester |
IT1247472B (en) | 1991-05-31 | 1994-12-17 | Fidia Spa | PROCESS FOR THE PREPARATION OF MICROSPHERES CONTAINING BIOLOGICALLY ACTIVE COMPONENTS. |
IT1254704B (en) | 1991-12-18 | 1995-10-09 | Mini Ricerca Scient Tecnolog | NON-WOVEN FABRIC ESSENTIALLY CONSTITUTED FROM DERIVATIVES OF HYALURONIC ACID |
IT1264322B (en) | 1992-07-30 | 1996-09-23 | Lanfranco Callegaro | SELF-CROSS-LINKED GELLANO ESTERS, PREPARATION PROCEDURE AND THEIR PHARMACEUTICAL AND BIOMEDICAL-SANITARY APPLICATIONS |
IT1259141B (en) | 1992-08-03 | 1996-03-11 | Fidia Spa | BIODEGRADABLE AND BIORIABSORBABLE GUIDE CHANNELS TO BE USED FOR TISSUE REPAIR AS ADJUVANT IN SURGICAL INTERVENTIONS |
FR2723847A1 (en) * | 1994-08-29 | 1996-03-01 | Debiopharm Sa | HEPARIN - BASED ANTITHROMBOTIC AND NON - HEMORRHAGIC COMPOSITIONS, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC APPLICATIONS. |
IT1282994B1 (en) * | 1996-05-10 | 1998-04-03 | Inalco Spa | DERIVATIVES OF THE POLYSACCHARIDE K5 HAVING HIGH ANTI-COAGULANT ACTIVITY |
IT1287698B1 (en) | 1996-08-29 | 1998-08-18 | Fidia Advanced Biopolymers Srl | SUTURE THREADS ESSENTIALLY MADE OF ESTERE DERIVATIVES OF HYALURONIC ACID |
-
1997
- 1997-07-28 IT IT97PD000170A patent/IT1294797B1/en active IP Right Grant
-
1998
- 1998-07-28 JP JP2000503879A patent/JP4417547B2/en not_active Expired - Fee Related
- 1998-07-28 AT AT98945104T patent/ATE311208T1/en active
- 1998-07-28 WO PCT/EP1998/004716 patent/WO1999004828A2/en active IP Right Grant
- 1998-07-28 IL IL13414098A patent/IL134140A0/en active IP Right Grant
- 1998-07-28 AU AU92555/98A patent/AU749627B2/en not_active Ceased
- 1998-07-28 ES ES98945104T patent/ES2253827T3/en not_active Expired - Lifetime
- 1998-07-28 CA CA002298733A patent/CA2298733C/en not_active Expired - Lifetime
- 1998-07-28 DK DK98945104T patent/DK0999859T3/en active
- 1998-07-28 EP EP98945104A patent/EP0999859B1/en not_active Expired - Lifetime
- 1998-07-28 DE DE69832616T patent/DE69832616T2/en not_active Expired - Lifetime
-
2000
- 2000-01-20 IL IL134140A patent/IL134140A/en not_active IP Right Cessation
- 2000-11-10 HK HK00107189A patent/HK1028210A1/en not_active IP Right Cessation
-
2002
- 2002-05-07 US US10/139,878 patent/US7202230B2/en not_active Expired - Fee Related
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0216453A2 (en) * | 1985-07-08 | 1987-04-01 | FIDIA S.p.A. | Esters of hyaluronic acid and their salts. |
EP0341745A1 (en) * | 1988-05-13 | 1989-11-15 | FIDIA S.p.A. | Crosslinked carboxy polysaccharides |
WO1990014110A1 (en) * | 1989-05-16 | 1990-11-29 | Jean Vilain | Improvements in or relating to pharmaceutical preparations |
WO1992019802A1 (en) * | 1991-05-01 | 1992-11-12 | C.V. Laboratories Limited | Alginate fabric, its use in wound dressings and surgical haemostats and a process for its manufacture |
WO1995025751A1 (en) * | 1994-03-23 | 1995-09-28 | Fidia Advanced Biopolymers Srl | Novel heparin-like sulfated polysaccharides |
WO1996035720A1 (en) * | 1995-05-10 | 1996-11-14 | Fidia Advanced Biopolymers S.R.L. | Heavy metal salts of succinic acid hemiesters with hyaluronic acid, or hyaluronic acid esters, a process for their preparation, and relative pharmaceutical compositions |
WO1997002845A1 (en) * | 1995-07-13 | 1997-01-30 | Bristol-Myers Squibb Company | A film for topical use in the treatment of wounds |
WO1997007833A2 (en) * | 1995-08-29 | 1997-03-06 | Fidia Advanced Biopolymers, S.R.L. | Biomaterials for preventing post-surgical adhesions comprised of hyaluronic acid derivatives |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9533069B2 (en) | 2008-02-29 | 2017-01-03 | Ferrosan Medical Devices A/S | Device for promotion of hemostasis and/or wound healing |
US9265858B2 (en) | 2012-06-12 | 2016-02-23 | Ferrosan Medical Devices A/S | Dry haemostatic composition |
Also Published As
Publication number | Publication date |
---|---|
JP2001510713A (en) | 2001-08-07 |
DE69832616T2 (en) | 2006-08-17 |
AU749627B2 (en) | 2002-06-27 |
JP4417547B2 (en) | 2010-02-17 |
ATE311208T1 (en) | 2005-12-15 |
CA2298733C (en) | 2009-09-01 |
DK0999859T3 (en) | 2006-03-27 |
DE69832616D1 (en) | 2006-01-05 |
US7202230B2 (en) | 2007-04-10 |
EP0999859A2 (en) | 2000-05-17 |
HK1028210A1 (en) | 2001-02-09 |
IT1294797B1 (en) | 1999-04-15 |
CA2298733A1 (en) | 1999-02-04 |
US20030060448A1 (en) | 2003-03-27 |
IL134140A0 (en) | 2001-04-30 |
EP0999859B1 (en) | 2005-11-30 |
AU9255598A (en) | 1999-02-16 |
IL134140A (en) | 2006-08-20 |
ITPD970170A1 (en) | 1999-01-28 |
ES2253827T3 (en) | 2006-06-01 |
WO1999004828A2 (en) | 1999-02-04 |
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