WO1999007738A2 - Human orphan receptor ntr-1 - Google Patents
Human orphan receptor ntr-1 Download PDFInfo
- Publication number
- WO1999007738A2 WO1999007738A2 PCT/US1998/016202 US9816202W WO9907738A2 WO 1999007738 A2 WO1999007738 A2 WO 1999007738A2 US 9816202 W US9816202 W US 9816202W WO 9907738 A2 WO9907738 A2 WO 9907738A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- ntr
- human
- human ntr
- polypeptide
- nucleic acid
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP98939199A EP1019502A2 (en) | 1997-08-06 | 1998-08-04 | Human orphan receptor ntr-1 |
JP2000506239A JP2001512667A (en) | 1997-08-06 | 1998-08-04 | Human orphan receptor NTR-1 |
CA002299619A CA2299619A1 (en) | 1997-08-06 | 1998-08-04 | Human orphan receptor ntr-1 |
AU87676/98A AU8767698A (en) | 1997-08-06 | 1998-08-04 | Novel orphan receptor |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5486997P | 1997-08-06 | 1997-08-06 | |
US60/054,869 | 1997-08-06 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1999007738A2 true WO1999007738A2 (en) | 1999-02-18 |
WO1999007738A3 WO1999007738A3 (en) | 1999-04-15 |
Family
ID=21994032
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1998/016202 WO1999007738A2 (en) | 1997-08-06 | 1998-08-04 | Human orphan receptor ntr-1 |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1019502A2 (en) |
JP (1) | JP2001512667A (en) |
AU (1) | AU8767698A (en) |
CA (1) | CA2299619A1 (en) |
WO (1) | WO1999007738A2 (en) |
Cited By (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999026977A1 (en) * | 1997-11-24 | 1999-06-03 | Biogen, Inc. | Novel receptors opg-2 |
WO1999031128A2 (en) * | 1997-12-16 | 1999-06-24 | Incyte Pharmaceuticals, Inc. | Human tumor necrosis factor-r2-like proteins |
WO1999046376A1 (en) * | 1998-03-09 | 1999-09-16 | Basf Aktiengesellschaft | Receptor from the superfamily of tnt-receptors from the human lung |
WO1999050413A2 (en) * | 1998-03-30 | 1999-10-07 | Eli Lilly And Company | THERAPEUTIC APPLICATIONS OF MATURE FLINT (mFLINT) POLYPEPTIDES OR OPG3, A MEMBER OF THE TNF RECEPTOR SUPERFAMILY |
WO2000037094A2 (en) * | 1998-12-22 | 2000-06-29 | Eli Lilly And Company | Therapeutic applications of flint polypeptides |
WO2001010908A1 (en) * | 1999-08-04 | 2001-02-15 | Amgen Inc. | Ntr3, a member of the tnf-receptor supergene family |
EP1159286A1 (en) * | 1999-03-04 | 2001-12-05 | Human Genome Sciences, Inc. | Tumor necrosis factor receptors 6 alpha and 6 beta |
JP2002542157A (en) * | 1999-03-11 | 2002-12-10 | ミレニアム・ファーマシューティカルズ・インコーポレイテッド | A method for identifying anti-GPR-9-6 and anti-TECK antibodies and modulators of GPR-9-6 and TECK functions. |
US6521422B1 (en) | 1999-08-04 | 2003-02-18 | Amgen Inc. | Fhm, a novel member of the TNF ligand supergene family |
US6627199B1 (en) | 1999-07-09 | 2003-09-30 | Amgen Inc | Isolation, identification and characterization of tmst2, a novel member of the TNF-receptor supergene family |
US6764679B2 (en) | 1997-09-18 | 2004-07-20 | Genentech, Inc. | Antibodies to DcR3 Polypeptide, a TNFR Homolog |
US6965012B1 (en) * | 1999-03-30 | 2005-11-15 | Eli Lilly And Company | Flint polypeptide analogs |
EP1666052A1 (en) | 2000-02-16 | 2006-06-07 | Genentech, Inc. | Uses of agonists and antagonists to modulate activity of TNF-related molecules |
US7125667B2 (en) | 1999-02-10 | 2006-10-24 | Serono Genetics Institute S.A. | Polymorphic markers of the LSR gene |
US7186800B1 (en) | 1997-01-14 | 2007-03-06 | Human Genome Sciences, Inc. | Tumor necrosis factor 6α and 6β |
US7252994B2 (en) | 2001-07-03 | 2007-08-07 | Genentech, Inc. | Human DR4 antibodies and uses thereof |
US7285267B2 (en) | 1997-01-14 | 2007-10-23 | Human Genome Sciences, Inc. | Tumor necrosis factor receptors 6α & 6β |
US7393661B2 (en) | 2000-01-14 | 2008-07-01 | Serono Genetics Institute S.A. | Nucleic acids encoding OBG3 polypeptides |
EP2014303A2 (en) | 2000-07-27 | 2009-01-14 | Genentech, Inc. | APO-2L receptor agonist and CPT-11 synergism |
US8722859B2 (en) | 2000-04-11 | 2014-05-13 | Genentech, Inc. | Multivalent antibodies and uses therefor |
US9726673B2 (en) | 2005-11-23 | 2017-08-08 | Genentech, Inc. | Methods and compositions related to B cell assays |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5447851A (en) * | 1992-04-02 | 1995-09-05 | Board Of Regents, The University Of Texas System | DNA encoding a chimeric polypeptide comprising the extracellular domain of TNF receptor fused to IgG, vectors, and host cells |
DE19654610A1 (en) * | 1995-12-22 | 1997-06-26 | Amgen Inc | Osteoproteger |
WO1998030694A2 (en) * | 1997-01-14 | 1998-07-16 | Human Genome Sciences, Inc. | TUMOR NECROSIS FACTOR RECEPTORS 6α AND 6$g(b) |
EP0861850A1 (en) * | 1997-02-04 | 1998-09-02 | Smithkline Beecham Corporation | Tumor necrosis related receptor, TR4 |
-
1998
- 1998-08-04 WO PCT/US1998/016202 patent/WO1999007738A2/en not_active Application Discontinuation
- 1998-08-04 JP JP2000506239A patent/JP2001512667A/en not_active Withdrawn
- 1998-08-04 CA CA002299619A patent/CA2299619A1/en not_active Abandoned
- 1998-08-04 EP EP98939199A patent/EP1019502A2/en not_active Withdrawn
- 1998-08-04 AU AU87676/98A patent/AU8767698A/en not_active Abandoned
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5447851A (en) * | 1992-04-02 | 1995-09-05 | Board Of Regents, The University Of Texas System | DNA encoding a chimeric polypeptide comprising the extracellular domain of TNF receptor fused to IgG, vectors, and host cells |
US5447851B1 (en) * | 1992-04-02 | 1999-07-06 | Univ Texas System Board Of | Dna encoding a chimeric polypeptide comprising the extracellular domain of tnf receptor fused to igg vectors and host cells |
DE19654610A1 (en) * | 1995-12-22 | 1997-06-26 | Amgen Inc | Osteoproteger |
WO1998030694A2 (en) * | 1997-01-14 | 1998-07-16 | Human Genome Sciences, Inc. | TUMOR NECROSIS FACTOR RECEPTORS 6α AND 6$g(b) |
EP0861850A1 (en) * | 1997-02-04 | 1998-09-02 | Smithkline Beecham Corporation | Tumor necrosis related receptor, TR4 |
Non-Patent Citations (2)
Title |
---|
HILLIER L ET AL: "Human cDNA clone 366305" EMBL SEQUENCE DATABASE,16 August 1996, XP002091562 HEIDELBERG DE cited in the application * |
HILLIER L ET AL: "Human cDNA clone 592256" EMBL SEQUENCE DATABASE,18 January 1997, XP002091560 HEIDELBERG DE cited in the application * |
Cited By (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8003386B1 (en) | 1997-01-14 | 2011-08-23 | Human Genome Sciences, Inc. | Tumor necrosis factor receptors 6α and 6β |
US7186800B1 (en) | 1997-01-14 | 2007-03-06 | Human Genome Sciences, Inc. | Tumor necrosis factor 6α and 6β |
US7285267B2 (en) | 1997-01-14 | 2007-10-23 | Human Genome Sciences, Inc. | Tumor necrosis factor receptors 6α & 6β |
US7534428B2 (en) | 1997-01-14 | 2009-05-19 | Human Genome Sciences, Inc. | Antibodies to tumor necrosis factor receptors 6α and 6β |
US7709218B2 (en) | 1997-01-14 | 2010-05-04 | Human Genome Sciences, Inc. | Tumor necrosis factor receptors 6α and 6β |
US6764679B2 (en) | 1997-09-18 | 2004-07-20 | Genentech, Inc. | Antibodies to DcR3 Polypeptide, a TNFR Homolog |
WO1999026977A1 (en) * | 1997-11-24 | 1999-06-03 | Biogen, Inc. | Novel receptors opg-2 |
WO1999031128A3 (en) * | 1997-12-16 | 1999-10-07 | Incyte Pharma Inc | Human tumor necrosis factor-r2-like proteins |
WO1999031128A2 (en) * | 1997-12-16 | 1999-06-24 | Incyte Pharmaceuticals, Inc. | Human tumor necrosis factor-r2-like proteins |
WO1999046376A1 (en) * | 1998-03-09 | 1999-09-16 | Basf Aktiengesellschaft | Receptor from the superfamily of tnt-receptors from the human lung |
WO1999050413A3 (en) * | 1998-03-30 | 1999-12-02 | Lilly Co Eli | Therapeutic applications of mature flint (mflint) polypeptides or opg3, a member of the tnf receptor superfamily |
WO1999050413A2 (en) * | 1998-03-30 | 1999-10-07 | Eli Lilly And Company | THERAPEUTIC APPLICATIONS OF MATURE FLINT (mFLINT) POLYPEPTIDES OR OPG3, A MEMBER OF THE TNF RECEPTOR SUPERFAMILY |
WO2000037094A3 (en) * | 1998-12-22 | 2000-11-09 | Lilly Co Eli | Therapeutic applications of flint polypeptides |
WO2000037094A2 (en) * | 1998-12-22 | 2000-06-29 | Eli Lilly And Company | Therapeutic applications of flint polypeptides |
US7125667B2 (en) | 1999-02-10 | 2006-10-24 | Serono Genetics Institute S.A. | Polymorphic markers of the LSR gene |
EP1159286A1 (en) * | 1999-03-04 | 2001-12-05 | Human Genome Sciences, Inc. | Tumor necrosis factor receptors 6 alpha and 6 beta |
EP1159286A4 (en) * | 1999-03-04 | 2003-01-15 | Human Genome Sciences Inc | Tumor necrosis factor receptors 6 alpha and 6 beta |
JP2002542157A (en) * | 1999-03-11 | 2002-12-10 | ミレニアム・ファーマシューティカルズ・インコーポレイテッド | A method for identifying anti-GPR-9-6 and anti-TECK antibodies and modulators of GPR-9-6 and TECK functions. |
US6965012B1 (en) * | 1999-03-30 | 2005-11-15 | Eli Lilly And Company | Flint polypeptide analogs |
US7320796B2 (en) | 1999-07-09 | 2008-01-22 | Amgen Inc. | Isolation, identification and characterization of tmst2, a novel member of the TNF-receptor supergene family |
US6627199B1 (en) | 1999-07-09 | 2003-09-30 | Amgen Inc | Isolation, identification and characterization of tmst2, a novel member of the TNF-receptor supergene family |
US6852839B2 (en) | 1999-08-04 | 2005-02-08 | Amgen, Inc. | Fhm, a novel member of the TNF ligand supergene family |
US6521422B1 (en) | 1999-08-04 | 2003-02-18 | Amgen Inc. | Fhm, a novel member of the TNF ligand supergene family |
US6599716B1 (en) | 1999-08-04 | 2003-07-29 | Amgen Inc. | Nucleic acids encoding NTR3, a member of the TNF-receptor supergene family |
US7118863B2 (en) | 1999-08-04 | 2006-10-10 | Amgen, Inc. | Methods for detecting NTR3 nucleic acids by hybridization |
US7544519B2 (en) | 1999-08-04 | 2009-06-09 | Amgen Inc. | Fhm a novel member of the TNF ligand supergene family: materials and methods for interaction modulators |
WO2001010908A1 (en) * | 1999-08-04 | 2001-02-15 | Amgen Inc. | Ntr3, a member of the tnf-receptor supergene family |
US7393661B2 (en) | 2000-01-14 | 2008-07-01 | Serono Genetics Institute S.A. | Nucleic acids encoding OBG3 polypeptides |
US7671024B2 (en) | 2000-01-14 | 2010-03-02 | Serono Genetics Institute S.A. | OBG3 globular head and uses thereof |
EP1666052A1 (en) | 2000-02-16 | 2006-06-07 | Genentech, Inc. | Uses of agonists and antagonists to modulate activity of TNF-related molecules |
US9493579B2 (en) | 2000-04-11 | 2016-11-15 | Genentech, Inc. | Multivalent antibodies and uses therefor |
US8722859B2 (en) | 2000-04-11 | 2014-05-13 | Genentech, Inc. | Multivalent antibodies and uses therefor |
EP2857516A1 (en) | 2000-04-11 | 2015-04-08 | Genentech, Inc. | Multivalent antibodies and uses therefor |
EP2014303A2 (en) | 2000-07-27 | 2009-01-14 | Genentech, Inc. | APO-2L receptor agonist and CPT-11 synergism |
US7744881B2 (en) | 2001-07-03 | 2010-06-29 | Genentech, Inc. | Human DR4 antibodies and uses thereof |
US7252994B2 (en) | 2001-07-03 | 2007-08-07 | Genentech, Inc. | Human DR4 antibodies and uses thereof |
US9726673B2 (en) | 2005-11-23 | 2017-08-08 | Genentech, Inc. | Methods and compositions related to B cell assays |
Also Published As
Publication number | Publication date |
---|---|
AU8767698A (en) | 1999-03-01 |
WO1999007738A3 (en) | 1999-04-15 |
JP2001512667A (en) | 2001-08-28 |
CA2299619A1 (en) | 1999-02-18 |
EP1019502A2 (en) | 2000-07-19 |
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