WO1999039001A3 - Nucleic acid analysis method - Google Patents
Nucleic acid analysis method Download PDFInfo
- Publication number
- WO1999039001A3 WO1999039001A3 PCT/EP1999/000918 EP9900918W WO9939001A3 WO 1999039001 A3 WO1999039001 A3 WO 1999039001A3 EP 9900918 W EP9900918 W EP 9900918W WO 9939001 A3 WO9939001 A3 WO 9939001A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- nucleic acid
- array
- analysis method
- acid analysis
- probes
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
- C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
Abstract
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000529458A JP2002501760A (en) | 1998-02-02 | 1999-02-02 | Nucleic acid analysis method |
US09/601,258 US6280954B1 (en) | 1998-02-02 | 1999-02-02 | Arrayed primer extension technique for nucleic acid analysis |
EP99911663A EP1051523A2 (en) | 1998-02-02 | 1999-02-02 | Nucleic acid analysis method |
AU30276/99A AU3027699A (en) | 1998-02-02 | 1999-02-02 | Nucleic acid analysis method |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP98300741 | 1998-02-02 | ||
EP98300741.0 | 1998-02-02 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1999039001A2 WO1999039001A2 (en) | 1999-08-05 |
WO1999039001A3 true WO1999039001A3 (en) | 1999-10-07 |
Family
ID=8234645
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP1999/000918 WO1999039001A2 (en) | 1998-02-02 | 1999-02-02 | Nucleic acid analysis method |
Country Status (5)
Country | Link |
---|---|
US (1) | US6280954B1 (en) |
EP (1) | EP1051523A2 (en) |
JP (1) | JP2002501760A (en) |
AU (1) | AU3027699A (en) |
WO (1) | WO1999039001A2 (en) |
Cited By (9)
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---|---|---|---|---|
US8883424B2 (en) | 1999-05-21 | 2014-11-11 | Illumina, Inc. | Use of microfluidic systems in the detection of target analytes using microsphere arrays |
US8906626B2 (en) | 2000-02-07 | 2014-12-09 | Illumina, Inc. | Multiplex nucleic acid reactions |
US9012144B2 (en) | 2003-11-12 | 2015-04-21 | Fluidigm Corporation | Short cycle methods for sequencing polynucleotides |
US9279148B2 (en) | 1999-04-20 | 2016-03-08 | Illumina, Inc. | Detection of nucleic acid reactions on bead arrays |
US9399795B2 (en) | 1998-06-24 | 2016-07-26 | Illumina, Inc. | Multiplex decoding of array sensors with microspheres |
US9410146B2 (en) | 2009-09-14 | 2016-08-09 | Qiagen Gaithersburg Inc. | Compositions and methods for recovery of nucleic acids or proteins from tissue samples fixed in cytology media |
US9416411B2 (en) | 1999-08-18 | 2016-08-16 | Illumina, Inc. | Compositions and methods for preparing oligonucleotide solutions |
US9422593B2 (en) | 2010-05-19 | 2016-08-23 | Qiagen Gaithresburg, Inc | Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids |
US9540689B2 (en) | 1998-05-01 | 2017-01-10 | Life Technologies Corporation | Method of determining the nucleotide sequence of oligonucleotides and DNA molecules |
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EP1032705B1 (en) | 1997-10-30 | 2011-12-14 | Cold Spring Harbor Laboratory | Probe arrays and methods of using probe arrays for distinguishing dna |
US7399589B2 (en) | 1998-02-06 | 2008-07-15 | Digene Corporation | Immunological detection of RNA:DNA hybrids on microarrays |
US6686151B1 (en) * | 1998-02-06 | 2004-02-03 | Digene Corporation | Immunological detection of RNA:DNA hybrids on microarrays |
US6780591B2 (en) | 1998-05-01 | 2004-08-24 | Arizona Board Of Regents | Method of determining the nucleotide sequence of oligonucleotides and DNA molecules |
US6544732B1 (en) | 1999-05-20 | 2003-04-08 | Illumina, Inc. | Encoding and decoding of array sensors utilizing nanocrystals |
US7501245B2 (en) | 1999-06-28 | 2009-03-10 | Helicos Biosciences Corp. | Methods and apparatuses for analyzing polynucleotide sequences |
US6448010B1 (en) | 1999-10-06 | 2002-09-10 | Amersham Pharmacia Biotech, Inc. | Method for detecting mutations using arrayed primer extension |
WO2001036679A2 (en) * | 1999-11-15 | 2001-05-25 | Hartwell John G | METHODS FOR GENERATING SINGLE STRANDED cDNA FRAGMENTS |
WO2001038580A2 (en) * | 1999-11-26 | 2001-05-31 | Curagen Corporation | Nucleic acid probe arrays |
WO2001057268A2 (en) | 2000-02-07 | 2001-08-09 | Illumina, Inc. | Nucleic acid detection methods using universal priming |
EP1967595A3 (en) | 2000-02-16 | 2008-12-03 | Illumina, Inc. | Parallel genotyping of multiple patient samples |
US6376191B1 (en) * | 2000-03-22 | 2002-04-23 | Mergen, Ltd. | Microarray-based analysis of polynucleotide sequence variations |
AU2001257448A1 (en) * | 2000-05-01 | 2001-11-12 | Cold Spring Harbor Laboratory | Use of representations of dna for genetic analysis |
US7601497B2 (en) | 2000-06-15 | 2009-10-13 | Qiagen Gaithersburg, Inc. | Detection of nucleic acids by target-specific hybrid capture method |
US7439016B1 (en) | 2000-06-15 | 2008-10-21 | Digene Corporation | Detection of nucleic acids by type-specific hybrid capture method |
CH699253B1 (en) * | 2000-09-18 | 2010-02-15 | Eidgenoessische Forschungsanst | A method of characterizing and / or identification of genomes. |
US20020155476A1 (en) | 2000-10-20 | 2002-10-24 | Nader Pourmand | Transient electrical signal based methods and devices for characterizing molecular interaction and/or motion in a sample |
EP1207209A3 (en) * | 2000-11-09 | 2002-09-11 | Agilent Technologies, Inc. (a Delaware corporation) | Methods using arrays for detection of single nucleotide polymorphisms |
WO2002059357A2 (en) * | 2001-01-24 | 2002-08-01 | Genomic Expression Aps | Assay and kit for analyzing gene expression |
US20040038206A1 (en) * | 2001-03-14 | 2004-02-26 | Jia Zhang | Method for high throughput assay of genetic analysis |
US20030017567A1 (en) * | 2001-04-24 | 2003-01-23 | 3M Innovative Properties Company | Biological sample processing methods and compositions that include surfactants |
US6617136B2 (en) * | 2001-04-24 | 2003-09-09 | 3M Innovative Properties Company | Biological sample processing methods and compositions that include surfactants |
US20030036073A1 (en) * | 2001-06-07 | 2003-02-20 | Saba James Anthony | Matrix Sequencing: a novel method of polynucleotide analysis utilizing probes containing universal nucleotides |
US9261460B2 (en) | 2002-03-12 | 2016-02-16 | Enzo Life Sciences, Inc. | Real-time nucleic acid detection processes and compositions |
US20040161741A1 (en) * | 2001-06-30 | 2004-08-19 | Elazar Rabani | Novel compositions and processes for analyte detection, quantification and amplification |
US9777312B2 (en) * | 2001-06-30 | 2017-10-03 | Enzo Life Sciences, Inc. | Dual polarity analysis of nucleic acids |
US20030087298A1 (en) * | 2001-11-02 | 2003-05-08 | Roland Green | Detection of hybridization on oligonucleotide microarray through covalently labeling microarray probe |
US20030170637A1 (en) * | 2002-03-06 | 2003-09-11 | Pirrung Michael C. | Method of analyzing mRNA splice variants |
US9353405B2 (en) | 2002-03-12 | 2016-05-31 | Enzo Life Sciences, Inc. | Optimized real time nucleic acid detection processes |
US20030186252A1 (en) * | 2002-04-01 | 2003-10-02 | Ilsley Diane D. | Array based hybridization assays employing enzymatically generated labeled target nucleic acids and compositions for practicing the same |
WO2004065000A1 (en) | 2003-01-21 | 2004-08-05 | Illumina Inc. | Chemical reaction monitor |
RU2390561C2 (en) | 2003-05-23 | 2010-05-27 | Колд Спринг Харбор Лэборетери | Virtual sets of fragments of nucleotide sequences |
US20040259100A1 (en) * | 2003-06-20 | 2004-12-23 | Illumina, Inc. | Methods and compositions for whole genome amplification and genotyping |
EP1636337A4 (en) | 2003-06-20 | 2007-07-04 | Illumina Inc | Methods and compositions for whole genome amplification and genotyping |
US20050181394A1 (en) * | 2003-06-20 | 2005-08-18 | Illumina, Inc. | Methods and compositions for whole genome amplification and genotyping |
US20050048544A1 (en) * | 2003-07-10 | 2005-03-03 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for determining whether a subject carries a cystic fibrosis transmembrane conductance regulator (CFTR) gene mutation |
US20050153320A1 (en) * | 2003-11-06 | 2005-07-14 | Herron James N. | Single base extension |
WO2005080605A2 (en) | 2004-02-19 | 2005-09-01 | Helicos Biosciences Corporation | Methods and kits for analyzing polynucleotide sequences |
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US7666593B2 (en) | 2005-08-26 | 2010-02-23 | Helicos Biosciences Corporation | Single molecule sequencing of captured nucleic acids |
US20070196832A1 (en) * | 2006-02-22 | 2007-08-23 | Efcavitch J William | Methods for mutation detection |
WO2010062556A1 (en) | 2008-10-27 | 2010-06-03 | Qiagen Gaithersburg Inc. | Fast results hybrid capture assay and system |
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Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991005060A2 (en) * | 1989-09-29 | 1991-04-18 | Applied Biosystems, Inc. | Spectrally resolvable rhodamine dyes for nucleic acid sequence determination |
WO1991014001A2 (en) * | 1990-03-14 | 1991-09-19 | E.I. Du Pont De Nemours And Company | A process for distinguishing nucleic acids on the basis of nucleotide differences |
EP0534858A1 (en) * | 1991-09-24 | 1993-03-31 | Keygene N.V. | Selective restriction fragment amplification : a general method for DNA fingerprinting |
WO1993017126A1 (en) * | 1992-02-19 | 1993-09-02 | The Public Health Research Institute Of The City Of New York, Inc. | Novel oligonucleotide arrays and their use for sorting, isolating, sequencing, and manipulating nucleic acids |
EP0630972A2 (en) * | 1993-06-25 | 1994-12-28 | Hitachi, Ltd. | DNA analyzing method |
EP0649852A1 (en) * | 1993-10-26 | 1995-04-26 | Hitachi, Ltd. | Fractionation method for nucleotide fragments |
EP0701001A2 (en) * | 1994-09-07 | 1996-03-13 | Hitachi, Ltd. | DNA separating, fractionating and analyzing method and system therefor |
WO1996041893A1 (en) * | 1995-06-09 | 1996-12-27 | The University Of Tennessee Research Corporation | Methods for the generation of sequence signatures from nucleic acids |
WO1997022720A1 (en) * | 1995-12-21 | 1997-06-26 | Kenneth Loren Beattie | Arbitrary sequence oligonucleotide fingerprinting |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6004744A (en) * | 1991-03-05 | 1999-12-21 | Molecular Tool, Inc. | Method for determining nucleotide identity through extension of immobilized primer |
US5981176A (en) * | 1992-06-17 | 1999-11-09 | City Of Hope | Method of detecting and discriminating between nucleic acid sequences |
US5503980A (en) * | 1992-11-06 | 1996-04-02 | Trustees Of Boston University | Positional sequencing by hybridization |
-
1999
- 1999-02-02 US US09/601,258 patent/US6280954B1/en not_active Expired - Fee Related
- 1999-02-02 JP JP2000529458A patent/JP2002501760A/en active Pending
- 1999-02-02 EP EP99911663A patent/EP1051523A2/en not_active Withdrawn
- 1999-02-02 WO PCT/EP1999/000918 patent/WO1999039001A2/en not_active Application Discontinuation
- 1999-02-02 AU AU30276/99A patent/AU3027699A/en not_active Abandoned
Patent Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1991005060A2 (en) * | 1989-09-29 | 1991-04-18 | Applied Biosystems, Inc. | Spectrally resolvable rhodamine dyes for nucleic acid sequence determination |
WO1991014001A2 (en) * | 1990-03-14 | 1991-09-19 | E.I. Du Pont De Nemours And Company | A process for distinguishing nucleic acids on the basis of nucleotide differences |
EP0534858A1 (en) * | 1991-09-24 | 1993-03-31 | Keygene N.V. | Selective restriction fragment amplification : a general method for DNA fingerprinting |
WO1993017126A1 (en) * | 1992-02-19 | 1993-09-02 | The Public Health Research Institute Of The City Of New York, Inc. | Novel oligonucleotide arrays and their use for sorting, isolating, sequencing, and manipulating nucleic acids |
EP0630972A2 (en) * | 1993-06-25 | 1994-12-28 | Hitachi, Ltd. | DNA analyzing method |
EP0649852A1 (en) * | 1993-10-26 | 1995-04-26 | Hitachi, Ltd. | Fractionation method for nucleotide fragments |
EP0701001A2 (en) * | 1994-09-07 | 1996-03-13 | Hitachi, Ltd. | DNA separating, fractionating and analyzing method and system therefor |
WO1996041893A1 (en) * | 1995-06-09 | 1996-12-27 | The University Of Tennessee Research Corporation | Methods for the generation of sequence signatures from nucleic acids |
WO1997022720A1 (en) * | 1995-12-21 | 1997-06-26 | Kenneth Loren Beattie | Arbitrary sequence oligonucleotide fingerprinting |
Cited By (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9540689B2 (en) | 1998-05-01 | 2017-01-10 | Life Technologies Corporation | Method of determining the nucleotide sequence of oligonucleotides and DNA molecules |
US9399795B2 (en) | 1998-06-24 | 2016-07-26 | Illumina, Inc. | Multiplex decoding of array sensors with microspheres |
US9279148B2 (en) | 1999-04-20 | 2016-03-08 | Illumina, Inc. | Detection of nucleic acid reactions on bead arrays |
US9441267B2 (en) | 1999-04-20 | 2016-09-13 | Illumina, Inc. | Detection of nucleic acid reactions on bead arrays |
US8883424B2 (en) | 1999-05-21 | 2014-11-11 | Illumina, Inc. | Use of microfluidic systems in the detection of target analytes using microsphere arrays |
US9289766B2 (en) | 1999-05-21 | 2016-03-22 | Illumina, Inc. | Use of microfluidic systems in the detection of target analytes using microsphere arrays |
US9416411B2 (en) | 1999-08-18 | 2016-08-16 | Illumina, Inc. | Compositions and methods for preparing oligonucleotide solutions |
US8906626B2 (en) | 2000-02-07 | 2014-12-09 | Illumina, Inc. | Multiplex nucleic acid reactions |
US9012144B2 (en) | 2003-11-12 | 2015-04-21 | Fluidigm Corporation | Short cycle methods for sequencing polynucleotides |
US9410146B2 (en) | 2009-09-14 | 2016-08-09 | Qiagen Gaithersburg Inc. | Compositions and methods for recovery of nucleic acids or proteins from tissue samples fixed in cytology media |
US9422593B2 (en) | 2010-05-19 | 2016-08-23 | Qiagen Gaithresburg, Inc | Methods and compositions for sequence-specific purification and multiplex analysis of nucleic acids |
Also Published As
Publication number | Publication date |
---|---|
EP1051523A2 (en) | 2000-11-15 |
JP2002501760A (en) | 2002-01-22 |
AU3027699A (en) | 1999-08-16 |
US6280954B1 (en) | 2001-08-28 |
WO1999039001A2 (en) | 1999-08-05 |
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