WO1999044637A1 - Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue - Google Patents
Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue Download PDFInfo
- Publication number
- WO1999044637A1 WO1999044637A1 PCT/US1999/004798 US9904798W WO9944637A1 WO 1999044637 A1 WO1999044637 A1 WO 1999044637A1 US 9904798 W US9904798 W US 9904798W WO 9944637 A1 WO9944637 A1 WO 9944637A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- flux enhancer
- tissue
- micropore
- flux
- reservoir
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
- A61K41/0047—Sonopheresis, i.e. ultrasonically-enhanced transdermal delivery, electroporation of a pharmacologically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/0045—Devices for taking samples of body liquids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/20—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using laser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B10/0045—Devices for taking samples of body liquids
- A61B2010/008—Interstitial fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00743—Type of operation; Specification of treatment sites
- A61B2017/00747—Dermatology
- A61B2017/00765—Decreasing the barrier function of skin tissue by radiated energy, e.g. using ultrasound, using laser for skin perforation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Pathology (AREA)
- Hematology (AREA)
- Biophysics (AREA)
- Medical Informatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- Surgical Instruments (AREA)
- Medicinal Preparation (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- External Artificial Organs (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Description
Claims
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT99911120T ATE273024T1 (en) | 1998-03-06 | 1999-03-05 | DEVICE FOR INCREASING THE FLUID FLOW SPEED IN A BIOLOGICAL TISSUE HAVING MICROPORES |
CA002329167A CA2329167C (en) | 1998-03-06 | 1999-03-05 | Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue |
DE69919335T DE69919335T2 (en) | 1998-03-06 | 1999-03-05 | DEVICE FOR INCREASING LIQUID FLOW SPEED IN A BIOLOGICAL TISSUE WITH MICROPORES |
JP2000534238A JP2002505304A (en) | 1998-03-06 | 1999-03-05 | Method and apparatus for enhancing the flux rate of a fluid in microporated biological tissue |
AU29840/99A AU747794B2 (en) | 1998-03-06 | 1999-03-05 | Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue |
EP99911120A EP1059939B1 (en) | 1998-03-06 | 1999-03-05 | Apparatus for enhancing flux rates of a fluid in a microporated biological tissue |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/036,053 US6173202B1 (en) | 1998-03-06 | 1998-03-06 | Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue |
US09/036,053 | 1998-03-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1999044637A1 true WO1999044637A1 (en) | 1999-09-10 |
Family
ID=21886346
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1999/004798 WO1999044637A1 (en) | 1998-03-06 | 1999-03-05 | Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue |
Country Status (10)
Country | Link |
---|---|
US (2) | US6173202B1 (en) |
EP (1) | EP1059939B1 (en) |
JP (3) | JP2002505304A (en) |
AT (1) | ATE273024T1 (en) |
AU (1) | AU747794B2 (en) |
CA (2) | CA2637760C (en) |
DE (1) | DE69919335T2 (en) |
DK (1) | DK1059939T3 (en) |
ES (1) | ES2226353T3 (en) |
WO (1) | WO1999044637A1 (en) |
Cited By (22)
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WO2000074767A2 (en) | 1999-06-08 | 2000-12-14 | Altea Technologies, Inc. | Apparatus for microporation of biological membranes using thin film tissue interface devices, and method therefor |
WO2001076553A2 (en) * | 2000-04-06 | 2001-10-18 | Sontra Medical, Inc. | Method and device for enhanced transdermal drug delivery |
US6352506B1 (en) | 1998-07-14 | 2002-03-05 | Altea Technologies | Controlled removal of biological membrane by pyrotechnic charge for transmembrane transport |
US6527716B1 (en) | 1997-12-30 | 2003-03-04 | Altea Technologies, Inc. | Microporation of tissue for delivery of bioactive agents |
US6790179B2 (en) | 2001-08-01 | 2004-09-14 | Johnson & Johnson Consumer Companies, Inc. | Method of examining and diagnosing skin health |
US6840910B2 (en) | 2001-08-01 | 2005-01-11 | Johnson & Johnson Consumer Companies, Inc. | Method of distributing skin care products |
US6855117B2 (en) | 2001-08-01 | 2005-02-15 | Johnson & Johnson Consumer Companies, Inc. | Method of treating the skin of a subject |
US6882884B1 (en) | 2000-10-13 | 2005-04-19 | Soundskin, L.L.C. | Process for the stimulation of production of extracellular dermal proteins in human tissue |
US7141034B2 (en) | 2000-06-08 | 2006-11-28 | Altea Therapeutics Corporation | Transdermal drug delivery device, method of making same and method of using same |
WO2008091878A1 (en) | 2007-01-22 | 2008-07-31 | Altea Therapeutics Corporation | Transdermal porator and patch system and method for using same |
US7611723B2 (en) | 2002-03-26 | 2009-11-03 | Nanocyte Inc. | Stinging cells expressing an exogenous polynucleotide encoding a therapeutic, diagnostic or a cosmetic agent and methods compositions and devices utilizing such stinging cells or capsules derived therefrom for delivering the therapeutic, diagnostic or cosmetic agent into a tissue |
US7632522B2 (en) | 2000-09-28 | 2009-12-15 | Nanocyte Inc. | Use of stinging cells/capsules for the delivery of active agents to keratinous substances |
US8062660B2 (en) | 2000-09-28 | 2011-11-22 | Nanocyte Inc. | Methods compositions and devices utilizing stinging cells/capsules for delivering a therapeutic or a cosmetic agent into a tissue |
US8281675B2 (en) | 2007-10-17 | 2012-10-09 | Syneron Medical Ltd | Dissolution rate verification |
US8337493B2 (en) | 2002-04-19 | 2012-12-25 | Syneron Medical Ltd | Handheld transdermal drug delivery and analyte extraction |
US8834862B2 (en) | 2005-04-19 | 2014-09-16 | Nanocyte Inc. | Methods, compositions and devices utilizing stinging cells/capsules for conditioning a tissue prior to delivery of an active agent |
US9011419B2 (en) | 2007-12-05 | 2015-04-21 | Syneron Medical Ltd | Disposable electromagnetic energy applicator |
US9037229B2 (en) | 2007-10-09 | 2015-05-19 | Syneron Medical Ltd | Magnetic patch coupling |
US9033950B2 (en) | 2003-10-24 | 2015-05-19 | Nitto Denko Corporation | Method for transdermal delivery of permeant substances |
US9504826B2 (en) | 2009-02-18 | 2016-11-29 | Syneron Medical Ltd | Skin treatment apparatus for personal use and method for using same |
US9579380B2 (en) | 1996-12-31 | 2017-02-28 | Ntt Denko Corporation | Microporation of tissue for delivery of bioactive agents |
US9918665B2 (en) | 2002-03-11 | 2018-03-20 | Nitto Denko Corporation | Transdermal porator and patch system and method for using same |
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US6797276B1 (en) * | 1996-11-14 | 2004-09-28 | The United States Of America As Represented By The Secretary Of The Army | Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response |
US20060002959A1 (en) * | 1996-11-14 | 2006-01-05 | Government Of The United States | Skin-sctive adjuvants for transcutaneous immuization |
US5980898A (en) * | 1996-11-14 | 1999-11-09 | The United States Of America As Represented By The U.S. Army Medical Research & Material Command | Adjuvant for transcutaneous immunization |
US20060002949A1 (en) * | 1996-11-14 | 2006-01-05 | Army Govt. Of The Usa, As Rep. By Secretary Of The Office Of The Command Judge Advocate, Hq Usamrmc. | Transcutaneous immunization without heterologous adjuvant |
US6517532B1 (en) * | 1997-05-15 | 2003-02-11 | Palomar Medical Technologies, Inc. | Light energy delivery head |
US6273884B1 (en) | 1997-05-15 | 2001-08-14 | Palomar Medical Technologies, Inc. | Method and apparatus for dermatology treatment |
US8182473B2 (en) * | 1999-01-08 | 2012-05-22 | Palomar Medical Technologies | Cooling system for a photocosmetic device |
US20060149343A1 (en) * | 1996-12-02 | 2006-07-06 | Palomar Medical Technologies, Inc. | Cooling system for a photocosmetic device |
US8313480B2 (en) * | 2004-10-02 | 2012-11-20 | Joseph Neev | Device and method for treating skin disorders with thermal energy |
US7981112B1 (en) | 1997-08-12 | 2011-07-19 | Joseph Neev | Home use device and methods for treating skin conditions |
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US6173202B1 (en) * | 1998-03-06 | 2001-01-09 | Spectrx, Inc. | Method and apparatus for enhancing flux rates of a fluid in a microporated biological tissue |
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US6059820A (en) | 1998-10-16 | 2000-05-09 | Paradigm Medical Corporation | Tissue cooling rod for laser surgery |
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Also Published As
Publication number | Publication date |
---|---|
JP2002505304A (en) | 2002-02-19 |
JP2007195999A (en) | 2007-08-09 |
DK1059939T3 (en) | 2004-12-06 |
CA2329167A1 (en) | 1999-09-10 |
ES2226353T3 (en) | 2005-03-16 |
DE69919335D1 (en) | 2004-09-16 |
JP2011005283A (en) | 2011-01-13 |
CA2637760A1 (en) | 1999-09-10 |
EP1059939B1 (en) | 2004-08-11 |
CA2329167C (en) | 2008-11-18 |
EP1059939A1 (en) | 2000-12-20 |
CA2637760C (en) | 2015-01-06 |
DE69919335T2 (en) | 2005-08-11 |
US6508785B1 (en) | 2003-01-21 |
ATE273024T1 (en) | 2004-08-15 |
US6173202B1 (en) | 2001-01-09 |
AU2984099A (en) | 1999-09-20 |
AU747794B2 (en) | 2002-05-23 |
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