WO1999047543A3 - Sustained-release composition including amorphous polymer - Google Patents
Sustained-release composition including amorphous polymer Download PDFInfo
- Publication number
- WO1999047543A3 WO1999047543A3 PCT/US1999/006198 US9906198W WO9947543A3 WO 1999047543 A3 WO1999047543 A3 WO 1999047543A3 US 9906198 W US9906198 W US 9906198W WO 9947543 A3 WO9947543 A3 WO 9947543A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- composition
- sustained
- composition including
- release composition
- amorphous polymer
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/541—Organic ions forming an ion pair complex with the pharmacologically or therapeutically active agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/554—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being a steroid plant sterol, glycyrrhetic acid, enoxolone or bile acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
- A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
Abstract
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU31082/99A AU3108299A (en) | 1998-03-18 | 1999-03-18 | Sustained-release composition including amorphous polymer |
EP99912785A EP1073419A4 (en) | 1998-03-18 | 1999-03-18 | Sustained-release composition including amorphous polymer |
JP2000536736A JP2002506876A (en) | 1998-03-18 | 1999-03-18 | Sustained release composition comprising an amorphous polymer |
CA002324254A CA2324254C (en) | 1998-03-18 | 1999-03-18 | Sustained-release composition including amorphous polymer |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7839098P | 1998-03-18 | 1998-03-18 | |
US60/078,390 | 1998-03-18 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09403412 A-371-Of-International | 2000-03-08 | ||
US09/877,330 Continuation US6613358B2 (en) | 1998-03-18 | 2001-06-07 | Sustained-release composition including amorphous polymer |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1999047543A2 WO1999047543A2 (en) | 1999-09-23 |
WO1999047543A3 true WO1999047543A3 (en) | 1999-11-04 |
Family
ID=22143753
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1999/006198 WO1999047543A2 (en) | 1998-03-18 | 1999-03-18 | Sustained-release composition including amorphous polymer |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1073419A4 (en) |
JP (1) | JP2002506876A (en) |
AU (1) | AU3108299A (en) |
CA (1) | CA2324254C (en) |
WO (1) | WO1999047543A2 (en) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2815540B1 (en) † | 2000-10-19 | 2005-06-10 | Separex Sa | PROCESS FOR MANUFACTURING VERY FINE PARTICLES COMPRISING A PRINCIPLE INSERTED IN A HOST MOLECULE |
NZ530315A (en) * | 2001-07-10 | 2007-01-26 | Corixa Corp | Compositions and methods for delivery of proteins and adjuvants encapsulated in microspheres |
GB0216780D0 (en) * | 2002-07-19 | 2002-08-28 | Bradford Particle Design Ltd | Methods of particle formation |
EP1452177A1 (en) * | 2003-02-27 | 2004-09-01 | Boehringer Ingelheim International GmbH | Pharmaceutical formulations comprising sodium laurylsulfate as bitterness masking agent |
US9682043B2 (en) | 2003-12-09 | 2017-06-20 | Medcrystalforms, Llc | Method of preparation of mixed phase co-crystals with active agents |
US8399007B2 (en) | 2006-12-05 | 2013-03-19 | Landec Corporation | Method for formulating a controlled-release pharmaceutical formulation |
EP2500015A1 (en) | 2006-12-05 | 2012-09-19 | Landec Corporation | Delivery of drugs |
US8114883B2 (en) | 2007-12-04 | 2012-02-14 | Landec Corporation | Polymer formulations for delivery of bioactive materials |
CN102131483A (en) | 2008-02-08 | 2011-07-20 | 昌达生物科技公司 | Non-polymeric compositions for controllable drug delivery |
BR112016002342A8 (en) * | 2013-08-06 | 2018-01-23 | Dong Kook Pharm Co Ltd | entecavir microsphere, method for preparation of an entecavir microsphere, and pharmaceutical composition |
KR20170054459A (en) | 2014-09-10 | 2017-05-17 | 더블 본드 파마슈티컬스 에이비 | Targeted delivery of hydrophilic drugs |
WO2017153052A1 (en) * | 2016-03-07 | 2017-09-14 | Double Bond Pharmaceuticals Ab | Targeted delivery of hydrophilic drugs to lung |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4526938A (en) * | 1982-04-22 | 1985-07-02 | Imperial Chemical Industries Plc | Continuous release formulations |
US4582820A (en) * | 1982-12-23 | 1986-04-15 | Research Corporation | Orally administered biologically active peptides and proteins |
US5445832A (en) * | 1991-07-22 | 1995-08-29 | Debio Recherche Pharmaceutique S.A. | Process for the preparation of microspheres made of a biodegradable polymeric material |
US5770559A (en) * | 1992-10-14 | 1998-06-23 | The Regents Of The University Of Colorado | Solubilization of pharmaceutical substances in an organic solvent and preparation of pharmaceutical powders using the same |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0817620B1 (en) * | 1995-03-28 | 2002-01-30 | Fidia Advanced Biopolymers, S.R.L. | Nanospheres comprising a biocompatible polysaccharide |
AU2676397A (en) * | 1996-04-18 | 1997-11-07 | University Technology Corporation | Methods for treating middle and inner ear disorders |
-
1999
- 1999-03-18 EP EP99912785A patent/EP1073419A4/en not_active Withdrawn
- 1999-03-18 JP JP2000536736A patent/JP2002506876A/en active Pending
- 1999-03-18 AU AU31082/99A patent/AU3108299A/en not_active Abandoned
- 1999-03-18 CA CA002324254A patent/CA2324254C/en not_active Expired - Lifetime
- 1999-03-18 WO PCT/US1999/006198 patent/WO1999047543A2/en active Application Filing
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4526938A (en) * | 1982-04-22 | 1985-07-02 | Imperial Chemical Industries Plc | Continuous release formulations |
US4582820A (en) * | 1982-12-23 | 1986-04-15 | Research Corporation | Orally administered biologically active peptides and proteins |
US5445832A (en) * | 1991-07-22 | 1995-08-29 | Debio Recherche Pharmaceutique S.A. | Process for the preparation of microspheres made of a biodegradable polymeric material |
US5770559A (en) * | 1992-10-14 | 1998-06-23 | The Regents Of The University Of Colorado | Solubilization of pharmaceutical substances in an organic solvent and preparation of pharmaceutical powders using the same |
Non-Patent Citations (1)
Title |
---|
See also references of EP1073419A4 * |
Also Published As
Publication number | Publication date |
---|---|
CA2324254C (en) | 2005-01-04 |
JP2002506876A (en) | 2002-03-05 |
WO1999047543A2 (en) | 1999-09-23 |
EP1073419A2 (en) | 2001-02-07 |
AU3108299A (en) | 1999-10-11 |
CA2324254A1 (en) | 1999-09-23 |
EP1073419A4 (en) | 2009-03-25 |
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