WO1999051163A1 - Hernia mesh - Google Patents
Hernia mesh Download PDFInfo
- Publication number
- WO1999051163A1 WO1999051163A1 PCT/EP1999/002199 EP9902199W WO9951163A1 WO 1999051163 A1 WO1999051163 A1 WO 1999051163A1 EP 9902199 W EP9902199 W EP 9902199W WO 9951163 A1 WO9951163 A1 WO 9951163A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- layer
- mesh
- hernia
- tissue
- set forth
- Prior art date
Links
Classifications
-
- D—TEXTILES; PAPER
- D04—BRAIDING; LACE-MAKING; KNITTING; TRIMMINGS; NON-WOVEN FABRICS
- D04B—KNITTING
- D04B21/00—Warp knitting processes for the production of fabrics or articles not dependent on the use of particular machines; Fabrics or articles defined by such processes
- D04B21/10—Open-work fabrics
- D04B21/12—Open-work fabrics characterised by thread material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0063—Implantable repair or support meshes, e.g. hernia meshes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/148—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
- A61F2250/003—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in adsorbability or resorbability, i.e. in adsorption or resorption time
-
- D—TEXTILES; PAPER
- D10—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
- D10B—INDEXING SCHEME ASSOCIATED WITH SUBLASSES OF SECTION D, RELATING TO TEXTILES
- D10B2509/00—Medical; Hygiene
- D10B2509/08—Hernia repair mesh
Definitions
- the present invention relates to a biologically active hernia mesh, and methods of its manufacture.
- the new trends for hernia repair include mini-invasive techniques, in which the hernia
- the plastic mesh will always become situated into close contact with the sensitive intra-abdominal organs.
- Bioabsorbable meshes made of polyglycolic acid and its lactide copolymer e.g.,
- lactide copolymers (with around 10 mol-% of lactide units) tend to lose their strength within
- a flexible, fibrous hernia mesh is provided, which
- the mesh has at least two functional
- hernia defect can be closed so that a) the second layer supports the area until the scar tissue is
- the second layer isolates the first layer from the abdominal cavity, preventing
- the mesh is placed on the uncovered fascia area
- the present invention relates to an implant, for hernia defect closure, for supporting
- hernioplasty can be improved, particularly to enhance the formation of scar tissue and to
- the hernia mesh of this invention is made from bioabsorbable polymers, copolymers, polymer blends or by combining various
- the hernia defect can be closed so that a) the
- second layer supports the hernia area
- the mesh of the invention is placed on the uncovered fascia area with its more
- the mesh is fixed with bioabsorbable sutures or
- the functions of the second layer are to support the hernia area until the scar
- tissue is strong enough to resist pressure and to prevent tissue to tissue adhesion onto the
- third layer a film
- the third layer can be included as part of the structure of the mesh.
- the hernia area through the mesh and onto the surrounding tissues.
- the mesh of the invention acts as a temporary support until the connective scar tissue
- the mesh according to this invention can be produced of fibers made of bioabsorbable
- mesh of this invention There are, for example, bioabsorbable aliphatic polyesters.
- the first layer of the mesh according to this invention is porous, with the optimal pore
- tissue cells to grow into the porosity of the mesh after implantation, and strengthens
- the second layer of the mesh according to this invention can be dense or porous, or a
- the optimal pore size is around 0.1 mm to
- layer is also soft and flexible, in order that the operation can still be accomplished through a laparoscope.
- the optional third layer of the mesh according to this invention is a dense, thin,
- bioabsorbable film which prevents agents that could cause tissue to tissue adhesion from moving from the hernia area through the mesh and onto the surrounding tissue, during the
- the third layer film also acts as a support layer immediately
- the thickness of the bioabsorbable film is optimally between 1-300 ⁇ m.
- the third layer is also soft and flexible in order that the operation through a laparoscope is
- a porous structure is most easily imbued in the mesh of this invention by making the
- porous structures can be used to make the mesh of this invention.
- Angiogenetic growth factors can be any suitable angiogenetic growth factors
- cyclosporine can be any substance that can accelerate the growth of connective tissue.
- cyclosporine can be any substance that can accelerate the growth of connective tissue.
- cyclosporine can be any substance that can accelerate the growth of connective tissue.
- the hernia mesh was made of commercial polyglycolide (PGA) biosbsorbable
- the filaments were then knitted by using a warp knitting machine, the fabric having a
- the hernia mesh was made using two different polymers as raw materials: the
- Example 1 The multifilament yarns were knitted into a form of hybrid fabric having a
- the mesh was sterilized with ethylene oxide gas.
- the hernia mesh was made of the commercial bioabsorbable PGA DEXON MESHTM,
- the patient was in general anesthesia and laying supine in an 20 degree
- Example 1 was introduced into the abdominal cavity, unrolled and placed on the
- peritoneal flap was then placed over the mesh and both were fixed onto the underlaying fascia
- the hernial defect is closed by a scar plate within 3 to 6 months, in which time the
- absorbable mesh composite will gradually lose its strength and consistency. In the end, no
- Lichtenstein's hernioplasty male patient: The patient lays supine. Some 10 to 20 ml
- inguinal canal was then incised and the spermatic cord detached from its attachments. This reveals the hernial sac and allows the surgeon to invert it back to the abdominal cavity.
- the mesh should now cover the entire inguinal canal allowing only the
- the mesh composite will induce fibroplacia to form a scar which, in 3 to 6 months, will support the bottom of the inguinal canal and prevent recurrent hernia formation.
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002326668A CA2326668A1 (en) | 1998-04-03 | 1999-03-31 | Hernia mesh |
AU38118/99A AU3811899A (en) | 1998-04-03 | 1999-03-31 | Hernia mesh |
JP2000541939A JP2002510523A (en) | 1998-04-03 | 1999-03-31 | Hernia mesh |
EP99920581A EP1079762A1 (en) | 1998-04-03 | 1999-03-31 | Hernia mesh |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/054,672 US6319264B1 (en) | 1998-04-03 | 1998-04-03 | Hernia mesh |
US09/054,672 | 1998-04-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1999051163A1 true WO1999051163A1 (en) | 1999-10-14 |
Family
ID=21992736
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP1999/002199 WO1999051163A1 (en) | 1998-04-03 | 1999-03-31 | Hernia mesh |
Country Status (6)
Country | Link |
---|---|
US (1) | US6319264B1 (en) |
EP (1) | EP1079762A1 (en) |
JP (1) | JP2002510523A (en) |
AU (1) | AU3811899A (en) |
CA (1) | CA2326668A1 (en) |
WO (1) | WO1999051163A1 (en) |
Cited By (75)
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---|---|---|---|---|
EP1038508A1 (en) * | 1999-03-20 | 2000-09-27 | Aesculap AG & Co. KG | Prosthetic patch, method for its manufacture and its use in surgery |
EP1099422A1 (en) * | 1999-11-10 | 2001-05-16 | DEUTSCHE INSTITUTE FÜR TEXTIL- UND FASERFORSCHUNG STUTTGART Stiftung des öffentlichen Rechts | Hernia patch and method of manufacture |
DE19959088A1 (en) * | 1999-12-08 | 2001-06-13 | Inst Textil & Faserforschung | Medical device, process for its manufacture and use |
DE10046119A1 (en) * | 2000-09-15 | 2002-03-28 | Inst Textil & Faserforschung | Medical bioresorbable implant, method of manufacture and use |
DE10122128A1 (en) * | 2001-04-27 | 2002-11-07 | Inst Polymerforschung Dresden | Absorbable patch implant, process for its production and use |
EP1306061A2 (en) * | 2001-10-19 | 2003-05-02 | Ethicon, Inc. | Absorbable mesh implant |
DE10155842A1 (en) * | 2001-11-14 | 2003-05-28 | Ethicon Gmbh | Flat implant |
WO2007014995A2 (en) * | 2005-08-03 | 2007-02-08 | Sofradim Production | Three-dimensional prosthetic tissue provided with a resorbable dense face |
EP1874226A2 (en) * | 2005-04-26 | 2008-01-09 | Poly-Med, Inc. | Absorbable/biodegradable composite yarns and property-modulated surgical implants therefrom |
US7704520B1 (en) | 2002-09-10 | 2010-04-27 | Mast Biosurgery Ag | Methods of promoting enhanced healing of tissues after cardiac surgery |
DE102008044005A1 (en) | 2008-11-24 | 2010-05-27 | Leibniz-Institut Für Polymerforschung Dresden E.V. | Planar implant for in abdominal wall region of patient during hernia surgery, has threads with cellular arrangement made in connecting area, where thread aligned parallel to cutting direction, is not present in wound area |
US7744915B2 (en) | 2002-07-31 | 2010-06-29 | Mast Biosurgery Ag | Apparatus and method for preventing adhesions between an implant and surrounding tissues |
US7947300B2 (en) | 2000-03-10 | 2011-05-24 | Mast Biosurgery Ag | Resorbable thin membranes |
EP2368521A1 (en) * | 2010-03-24 | 2011-09-28 | Tyco Healthcare Group LP | Therapeutic implant |
US8048444B2 (en) | 2002-07-31 | 2011-11-01 | Mast Biosurgery Ag | Apparatus and method for preventing adhesions between an implant and surrounding tissues |
US8182545B2 (en) | 2000-09-14 | 2012-05-22 | C.R. Bard, Inc. | Implantable prosthesis |
RU2460494C2 (en) * | 2010-06-15 | 2012-09-10 | Общество с ограниченной ответственностью предприятие "Репер НН" | Endoprosthesis for sutureless intraabdominal plasty in case of ventral hernias |
US8317808B2 (en) | 2008-02-18 | 2012-11-27 | Covidien Lp | Device and method for rolling and inserting a prosthetic patch into a body cavity |
US8709023B2 (en) | 2007-07-17 | 2014-04-29 | Poly-Med, Inc. | Absorbable / biodegradable composite yarn constructs and applications thereof |
US8758799B2 (en) | 2010-03-24 | 2014-06-24 | Covidien Lp | Therapeutic implant |
US8758798B2 (en) | 2010-03-24 | 2014-06-24 | Covidien Lp | Therapeutic implant |
US8758373B2 (en) | 2008-02-18 | 2014-06-24 | Covidien Lp | Means and method for reversibly connecting a patch to a patch deployment device |
RU2524196C1 (en) * | 2013-03-20 | 2014-07-27 | Общество с ограниченной ответственностью "Линтекс" | Reinforced warp mesh endoprosthesis for ventral hernia repair (versions) and method for using it |
US8808314B2 (en) | 2008-02-18 | 2014-08-19 | Covidien Lp | Device and method for deploying and attaching an implant to a biological tissue |
US8814887B2 (en) | 2005-03-01 | 2014-08-26 | Ethicon, Inc. | Surgical implant |
US8888811B2 (en) | 2008-10-20 | 2014-11-18 | Covidien Lp | Device and method for attaching an implant to biological tissue |
US8906045B2 (en) | 2009-08-17 | 2014-12-09 | Covidien Lp | Articulating patch deployment device and method of use |
US8932621B2 (en) | 2011-10-25 | 2015-01-13 | Covidien Lp | Implantable film/mesh composite |
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US9005308B2 (en) | 2011-10-25 | 2015-04-14 | Covidien Lp | Implantable film/mesh composite for passage of tissue therebetween |
US9034002B2 (en) | 2008-02-18 | 2015-05-19 | Covidien Lp | Lock bar spring and clip for implant deployment device |
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Also Published As
Publication number | Publication date |
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AU3811899A (en) | 1999-10-25 |
JP2002510523A (en) | 2002-04-09 |
EP1079762A1 (en) | 2001-03-07 |
CA2326668A1 (en) | 1999-10-14 |
US6319264B1 (en) | 2001-11-20 |
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