WO2000016818A9 - Functionalized derivatives of hyaluronic acid and formation of hydrogels in situ using same - Google Patents
Functionalized derivatives of hyaluronic acid and formation of hydrogels in situ using sameInfo
- Publication number
- WO2000016818A9 WO2000016818A9 PCT/EP1999/006913 EP9906913W WO0016818A9 WO 2000016818 A9 WO2000016818 A9 WO 2000016818A9 EP 9906913 W EP9906913 W EP 9906913W WO 0016818 A9 WO0016818 A9 WO 0016818A9
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- group
- hydrogel
- composition
- derivatives
- crosslinked
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0068—General culture methods using substrates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/08—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/14—Macromolecular materials
- A61L27/20—Polysaccharides
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
- C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan
- C08B37/0072—Hyaluronic acid, i.e. HA or hyaluronan; Derivatives thereof, e.g. crosslinked hyaluronic acid (hylan) or hyaluronates
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
- C08L5/08—Chitin; Chondroitin sulfate; Hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2533/00—Supports or coatings for cell culture, characterised by material
- C12N2533/70—Polysaccharides
- C12N2533/80—Hyaluronan
Abstract
Description
Claims
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99948783A EP1115433B1 (en) | 1998-09-18 | 1999-09-17 | Functionalized derivatives of hyaluronic acid, formation of hydrogels and in situ using same |
AU61922/99A AU6192299A (en) | 1998-09-18 | 1999-09-17 | Functionalized derivatives of hyaluronic acid and formation of hydrogels in situusing same |
AT99948783T ATE284229T1 (en) | 1998-09-18 | 1999-09-17 | FUNCTIONALIZED HYALURONIC ACID DERIVATIVES, FORMATION OF HYDROGELS AND THEIR USE IN SITU |
CA002344215A CA2344215A1 (en) | 1998-09-18 | 1999-09-17 | Functionalized derivatives of hyaluronic acid and formation of hydrogels in situ using same |
IL14206899A IL142068A0 (en) | 1998-09-18 | 1999-09-17 | Compositions containing a derivative of hyaluronic acid and methods for the preparation thereof |
DE69922522T DE69922522T2 (en) | 1998-09-18 | 1999-09-17 | FUNCTIONALIZED HYALURONIC ACID DERIVATIVES, FORMATION OF HYDROGELES AND THEIR USE IN SITU |
IL142068A IL142068A (en) | 1998-09-18 | 2001-03-18 | Compositions containing a derivative of hyaluronic acid and methods for the preparation thereof |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/156,829 | 1998-09-18 | ||
US09/156,829 US6630457B1 (en) | 1998-09-18 | 1998-09-18 | Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2000016818A1 WO2000016818A1 (en) | 2000-03-30 |
WO2000016818A9 true WO2000016818A9 (en) | 2000-08-24 |
Family
ID=22561268
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP1999/006913 WO2000016818A1 (en) | 1998-09-18 | 1999-09-17 | Functionalized derivatives of hyaluronic acid and formation of hydrogels in situ using same |
Country Status (8)
Country | Link |
---|---|
US (3) | US6630457B1 (en) |
EP (2) | EP1757314A1 (en) |
AT (1) | ATE284229T1 (en) |
AU (1) | AU6192299A (en) |
CA (1) | CA2344215A1 (en) |
DE (1) | DE69922522T2 (en) |
IL (2) | IL142068A0 (en) |
WO (1) | WO2000016818A1 (en) |
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US9242005B1 (en) | 2006-08-21 | 2016-01-26 | Abbott Cardiovascular Systems Inc. | Pro-healing agent formulation compositions, methods and treatments |
US9539410B2 (en) | 2005-04-19 | 2017-01-10 | Abbott Cardiovascular Systems Inc. | Methods and compositions for treating post-cardial infarction damage |
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CA2344215A1 (en) | 2000-03-30 |
ATE284229T1 (en) | 2004-12-15 |
EP1115433B1 (en) | 2004-12-08 |
AU6192299A (en) | 2000-04-10 |
DE69922522D1 (en) | 2005-01-13 |
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IL142068A0 (en) | 2002-03-10 |
EP1115433A1 (en) | 2001-07-18 |
WO2000016818A1 (en) | 2000-03-30 |
US6630457B1 (en) | 2003-10-07 |
DE69922522T2 (en) | 2005-12-15 |
IL142068A (en) | 2006-10-05 |
US20070149441A1 (en) | 2007-06-28 |
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