WO2000018333A1 - Heart valve having tissue retention with anchors and an outer sheath - Google Patents
Heart valve having tissue retention with anchors and an outer sheath Download PDFInfo
- Publication number
- WO2000018333A1 WO2000018333A1 PCT/US1999/021997 US9921997W WO0018333A1 WO 2000018333 A1 WO2000018333 A1 WO 2000018333A1 US 9921997 W US9921997 W US 9921997W WO 0018333 A1 WO0018333 A1 WO 0018333A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- tissue
- leaflets
- heart valve
- frame
- mounting frame
- Prior art date
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2409—Support rings therefor, e.g. for connecting valves to tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
- A61F2/2412—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body with soft flexible valve members, e.g. tissue valves shaped like natural valves
- A61F2/2415—Manufacturing methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2220/00—Fixations or connections for prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2220/0025—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements
- A61F2220/0075—Connections or couplings between prosthetic parts, e.g. between modular parts; Connecting elements sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
Definitions
- This invention relates to improvements in heart valves using autologous tissue held in place by anchors and an outer sheath.
- the heart valve can be constructed intraoperatively within a short time, typically 10 minutes.
- Heart valves are presently available for use in replacing diseased or malfunctioning heart valves in humans.
- One form of heart valve is constructed from animal tissue, typically from bovine or porcine aortic valve tissue. These valves must typically be constructed in a laboratory well in advance of when they will be needed and then stored in an aldehyde solution. Skilled technicians are required to assemble these valves.
- the valves constructed from animal tissue have relatively short lifetimes. The short lifetimes are caused by two factors. First, there is an antigenic reaction by the body to the animal tissue which causes the tissue to calcify, making it inflexible and more susceptible to failure with time.
- the tissue is often stored in glutaraldehyde before implantation to try to decrease the antigenic reaction.
- the aldehyde tends to tan the tissue to a leather-like consistency, which makes it wear out from the repeated stress of opening and closing.
- these animal tissue valves are widely used, they have to be replaced after about five to ten years. Replacing the valves poses risks to the patient, because a second open heart operation is then needed, with the attendant possibility of problems during the operation.
- Mechanical heart valves are also available. These valves are made from hard, non- biological materials such as metals or ceramics. Although the mechanical heart valves are durable, the hard, non-biological surfaces on the valves tend to cause blood clots. The blood clots can cause heart attacks or strokes, and, as a result, patients with mechanical heart valves must take anticoagulant drugs. These drugs can lead to hemorrhagic complications. Also, patients on these drugs require frequent and life-long laboratory tests of their clotting time. Another type of heart valve, the autogenous tissue valve, is constructed with the patient's own tissue. A number of patents for autologous tissue heart valves and methods of making autologous tissue heart valves have issued to Autogenics, assignee of this application, including U.S.
- This invention provides an improved apparatus and method for constructing an autologous heart valve.
- a significant factor of the invention is that both the configuration of the autologous tissue and its means for attachment to the frame of the valve prevent deleterious stress on the tissue.
- pericardium tissue taken from the patient into three separate tissue leaflets, each generally semi-circular shape and having a plurality of tissue anchor holes located along a tissue cusp line. The location of these tissue anchor holes correspond to tissue anchor hooks permanently attached to a tissue mounting frame.
- tissue anchor hooks of the tissue mounting frame are placed sequentially on the tissue anchor hooks of the tissue mounting frame so as to be located completely around the circumference of the tissue mounting frame.
- An elastomeric sheath is stretched over the exterior of the tissue mounting frame. This sheath prevents the tissue from coming off the tissue anchor hooks and rests gently on the tissue around the cusp line such that the tissue forms a naturally closed valve.
- a significant feature of this invention is that the manner in which the autologous tissue is supported prevents deterioration stress on the tissue.
- the tissue is thus not clamped between two unyielding members, but rather supported and retained by the combination of anchors mated in tissue anchor holes and the elastomeric sheath engaging a peripheral portion of the tissue leaflets between the elastomeric sheath member and the inner tissue mounting frame.
- tissue leaflets are formed to include sufficient extra tissue area to provide a physiologically representative coaptation line angle to thereby reduce the stretch in the tissue held in place by the sheath and thus further reduce the stress in the tissue.
- Figure 1 is a perspective view of a preferred embodiment of an assembled autologous heart valve constructed in accordance with this invention
- Figure 2A is a front view during manufacture of the inner frame portion of the tissue mounting frame
- Figure 2B is a front view during manufacture of the outer frame portion of the tissue mounting frame
- Figure 3A is a perspective view of the outer frame after it has been rolled into a cylindrical configuration
- Figure 3B is a perspective view of the inner and outer frames concentrically joined together
- FIG. 3C is a perspective of the completed tissue mounting frame with tissue anchors before it is covered with cloth;
- Figure 3D is an enlarged perspective view showing one of the commissure post anchors;
- Figure 4 is an enlarged view of the commissure tissue anchors
- Figure 5 is an enlarged view of the cusp tissue anchor
- Figure 6 is a cross-sectional view taken along line 6-6 of Figure 3C
- Figure 7A is a front view of one of the autologous tissue leaflets
- Figure 7B is a front view of the autologous tissue leaflet of Figure 7A, showing the excess tissue for overlap of the tissue leaflets on the commissure hooks;
- Figure 8 is the cross-sectional view of Figure 6 with the addition of two overlapping autologous tissue leaflets;
- Figure 9 A is a perspective view of the elastomeric sheath;
- Figure 9B is a cross-sectional view taken along line 9B-9B of Figure 9A;
- Figure 10A is a perspective view of the elastomeric sheath attached to the tissue mounting frame;
- Figure 1 OB is a front view of the elastomeric sheath shown in Figure 10A;
- Figure IOC is a sectional view taken along line IOC- IOC of Figure 1;
- Figure 11 A is a sectional view taken along line 11 A-l 1 A of Figure 1 ;
- Figure 1 IB is a cross-sectional view of line 11B-1 IB of Figure 1;
- Figure 1 IC is a cross-sectional view of line 11C-11C of Figure 1 ;
- Figure 12A is a perspective view of the annular sewing ring before it is covered with cloth;
- Figure 12B is a cross-sectional view taken along line 12B-12B of Figure 12 A; and Figure 13 illustrates the reduced coaptation angle ⁇ of the preferred embodiment of this invention.
- FIG 1 illustrates the preferred embodiment of the assembled autologous tissue heart valve 9 of this invention.
- This valve uses the patient's own tissue and is constructed intraoperatively from several factory manufactured components.
- these components include a tissue mounting frame 40 ( Figure 3C) having a plurality of tissue anchor hooks 34 and 36.
- This tissue mounting frame 40 mounts three individual autologous tissue leaflets 50, one such leaflet being shown in Figure 7A.
- the final assembled configuration of the three leaflets is shown at 90 in Figure 1.
- An elastomeric outer sheath 42 covers the tissue mounting frame and assists in holding the tissue in place on the frame without placing undue stress on the tissue leaflets.
- An annular sewing ring 70 is mounted at the base of the tissue mounting frame and elastomeric sheath and used in the conventional manner to hold the assembled valve 9 in place within the patient's heart. As described below, this valve is designed to be intraoperatively assembled by the surgeon during the open heart procedure. Typical assembly times are of the order of 10 minutes.
- Tissue Mounting Frame 40 The components of tissue mounting frame 40 are shown in Figures 2A, 2B, 3 A, 3B,
- FIG. 2A Shown in Figure 2A is the inner frame 10 preferably manufactured with a base 12 having three commissure posts 14 extending from the base. In the constructed valve shown in Figure 1, these commissure posts 14 are located along the axis of the valve in the direction of blood flow through the valve. Preferably, the three commissure posts 14 are spaced uniformly along the inner frame so that when the inner frame is assembled, the three commissure posts are separated by 120 degrees.
- the posts are preferably connected with scalloped walls 16 and the ends 18 of the inner frame are preferably slanted at an angle rather than being perpendicular to the base 12.
- a plurality of inner frame holes 20 are located along the perimeter of the scalloped walls 16 and commissure posts 14.
- the inner frame 10 may be made of a variety of materials suitable for in vivo use, including certain metals and plastics. Metal is generally preferred over plastic as a material of construction, and ELGILOY is an especially preferred metal for fabricating the inner frame 10. DELRIN is an especially preferred plastic.
- FIG. 2B shows the outer frame 24 portion of the tissue mounting frame 40.
- the outer frame just as the inner frame, is constructed with a base 12a with a plurality of commissure posts 14a connected by a scalloped walls 16a.
- the ends 18a of the outer frame are also preferably slanted.
- a plurality of outer frame holes 26 are located along a cusp line 30, shown as a dashed line in Figure 2B. This cusp line 30 is located close to the perimeter of the scalloped walls 16a and commissure posts 14a.
- the number of inner outer frame holes depend on the size of the valve but are generally in the range of 21 to 24. As described below, the outer frame holes are formed to be juxtaposed with the corresponding inner frame holes when the inner and outer frames are assembled together.
- the outer frame can also be made of a variety of materials including certain metals and plastics. ELGILOY is especially preferred.
- the general location of a weld area 32 is shown on Figure 2B with cross hatching. This weld area generally defines the area on the inner surface of the outer frame 24 which is later welded to the outer surface of the inner frame 10 to permanently bind the two frames together.
- the inner frame 10 and outer frame 24 are rolled to form a cylindrical configuration.
- the appearance of the two cylindrically shaped members are quite similar so that only the outer frame 24 is shown in Figure 3 A.
- the two members 10 and 24 are then placed concentrically together and spot welded in the weld area 32 around the base 12 to form the structure shown in Figure 3B.
- the frame ends 18 and 18a are placed 120 degrees apart when the two frames are welded together.
- Commissure post anchors 34 ( Figure 4) and cusp line anchors 36 ( Figure 5) are fabricated from metal, preferably ELGILOY.
- These anchors 34, 36 each include hook portions and a tang portion (34a and 36a), the latter being used to permanently attach the anchors to the tissue mounting frame 40.
- the hook portions are inserted from within the cylinder of the joined inner and outer frames through the inner frame holes 20 and outer frame holes 26 so that the hook portion extends outside of the surface of the outer frame (as shown in Figure 3C and 3B).
- the tang portion 36 is spot welded to the inner surface of the outer frame 24 through the corresponding larger inner frame hole 20 located in the inner frame 10.
- the tang portion 34a abuts the inner surface of the outer frame 24 and resides within the corresponding larger inner frame hole 20.
- the commissure post anchors 34 are slightly longer than the cusp line anchors 36, because they hold two layers of tissue rather than one layer for the cusp line anchors.
- Figure 3D shows a more detailed view of the commissure post anchors 34 which extend through the outer frame hole 26 in the outer frame 24.
- the tang portion of the commissure post anchor 34 is spot welded to the inner wall of the outer frame 24 through the larger inner frame hole 20 (not shown) of the inner frame 10.
- the tissue mounting frame 40 is manufactured in several sizes to suit the particular needs of the patient after the surgeon has removed the patient's valve during open heart surgery. Typical sizes in current use include 19, 21, 23 and 25 mm valves.
- the number of cusp line anchors vary, depending on the size of the tissue mounting frame. Normally, there are 6 commissure post anchors (2 per post) and 15-18 cusp line anchors per valve. The number of cusp line anchors depends on the size of the valve.
- Figure 6 shows a cross-sectional view of one side of the assembled tissue mounting frame 40 showing the inner frame 10, outer frame 24, and commissure post anchors 34.
- the two commissure post anchors 34 are welded to the inner wall of the outer frame 24 through the inner frame holes 20.
- the cusp line anchors 34 are similarly welded to the lower part of the frame 40.
- DACRON is the trademarked name registered to DuPont for polyethylene terephthalate.
- FIG. 10C, 11B, 11C show DACRON cloth 38 as a broken line 38 over the mounting frame 40 as well as the sheath 42 and sewing ring 70, described below.
- the commissure post anchors 34 and cusp line anchors 36 extend through the DACRON.
- the spot welded anchors are nearly flush with and only slightly protrude (typically 0.003 inches) above the inner surface of the inner frame.
- the inside surface is smooth, except for the knitted surface of the DACRON. Covering the frame with DACRON isolates the non-biological material, such as the metal of the frame, from the body.
- DACRON cover for the frame can be prepared in a variety of ways, one advantageous method was described in U.S. Patent No. 5,163,955, herein incorporated by reference.
- a three-fingered DACRON sock or glove is described and shown in Figure 4A of the patent.
- the three- fingered sock is formed by heat seaming sections of DACRON fabric together utilizing either hot wire, hot soldering iron, or ultrasonic techniques.
- the entire glove can be woven or knitted as one piece.
- the glove is then turned inside out (to remove the seam from the blood stream) pulled over the tissue frame and secured with a heat seam at the base of the glove. Similar fabrication methods can be used for the other DACRON coverings described herein.
- the autologous tissue leaflets 50 have a roughly semicircular shape as shown in Figure 7A. Details of these leaflets, including the manner in which they are formed, is provided below. These tissue leaflets 50 are formed with a plurality of tissue anchoring holes 58 located along a tissue cusp line 62, shown as a dashed line on Figure 7A. A tissue leaflet chamfer 66 is preferably cut in one corner to identify which leaflet is to be placed on top and overlap a portion of the preceding leaflet. During the intraoperative construction of the valve, these tissue holes 58 are fitted over the commissure post anchors 34 and cusp line anchors 36 to properly position the tissue leaflets to the assembled tissue frame.
- tissue leaflets 50 The attachment of the tissue leaflets 50 to the commissure post anchors is shown in Figure 8. As shown, overlapping tissue leaflets 50a and 50b are attached to the tissue mounting frame 40 by having the tissue anchoring holes 58 inserted over the hook portions commissure post anchors 34. As a result, two layers of tissue leaflets 50 are attached to each of the commissure post anchors 34. However, only one tissue leaflet is present in the lower part of the frame where the leaflets do not overlap.
- the cusp line anchors 36 (not shown in its Figure 8) have a hook portion that does not extend as far out from the frame 40.
- the elastomeric sheath 42 is shown in Figure 9A.
- This elastomeric sheath has a generally similar shape to that of the tissue mounting frame 40, with an annular elastomeric sheath base 44 and three elastomeric sheath commissure posts 46 extending from the base.
- the elastomeric sheath commissure posts 46 are connected with elastomeric sheath scalloped walls 48.
- a plurality of elastomeric sheath holes 64 correspond in position and number to those of the commissure post anchors 34 and the cusp line anchors 36 on the frame 40.
- the elastomeric sheath 42 is preferably made from silicone rubber covered on both sides with DACRON cloth.
- FIGS 9 A, 10A, 10B, 10C, 11A and 11B Additional views of the elastomeric sheath 42 are shown in Figures 9 A, 10A, 10B, 10C, 11A and 11B.
- Figures 10A, 10B and 11A are for illustrative purposes only since the sheath is shown in these figures attached to the frame 40 without the autologous leaflets 50. Such would not occur during construction of the valve since these leaflets would be first attached to the tissue mounting frame 40 by the tissue anchors 34, 36 and only afterwards is the sheath 42 moved into position.
- the cross-section of the elastomeric sheath 42, shown best in Figure 9B, is somewhat like an inverted "J" with two rims adjacent to the elastomeric sheath base 44.
- the elastomeric sheath 42 is designed to be stretch-fit over the assembled frame structure having the three leaflets 50 attached.
- the tissue anchors 34 and 36 locate loosely within the Dacron covered elastomeric sheath holes 50, as best shown in Figure 1 IB.
- the top of the inverted "J" of the outer elastomeric sheath fits over the top of the commissure posts 14 of the frame 40.
- the tissue leaflets 50 attached to the commissure post anchors 34 and the cusp line hooks 36 are then held in place between the inner wall of the elastomeric sheath 42 and the tissue mounting frame 40.
- the elastomeric sheath holes 64 accommodate the hook section of the commissure post anchors 34 and cusp line anchors 36 which protrude beyond the tissue.
- Figure 10A shows the commissure post anchors 34 and cusp line anchors 36 fitted into the elastomeric sheath holes 64.
- the elastomeric sheath 42 is fixed by its DACRON cover to the base of the frame assembly by thermally welding, suturing, or sewing it to the DACRON cover of the frame assembly.
- the elastomeric sheath 42 is also held in position on the commissure posts 14 of the frame by a elastomeric sheath pocket 84 situated at the top of the inverted "J" of the outer sheath ( Figure 1 IB).
- Sewing Ring A DACRON covered sewing ring 70 shown in Figures 11 A, 1 IB, 1 IC and 12A, 12B, is located at the base of the assembled valve.
- the sewing ring advantageously has a wedge shaped cross-section and is preferably made of silicon rubber, though other materials can be used, provided that they are flexible, resilient, and durable.
- the sewing ring is thin and flexible so that it can accurately conform to the scalloped shape of the aortic root when the valve is implanted into the patient.
- the sewing ring, tissue mounting frame, and elastomeric sheath are joined together by joining all six layers of DACRON together in a thermal weld point 110, shown in Figures 1 IB and l lC.
- the thermal weld 110 is formed with the sewing ring almost in line with the tissue mounting frame.
- the weld point is hidden between the sewing ring and the outer sheath. This prevents thromboembolisms from forming on the relatively smooth surface of the weld.
- the tissue mounting frame, tissue anchors, and elastomeric sheath comprise a kit which can be preassembled in the factory and shipped for use in an operating room.
- the kit can be fitted together and the elastomeric sheath aligned with the tissue mounting frame in the factory.
- the tissue mounting frame, and elastomeric sheath are covered with DACRON, and the layers of DACRON are welded together with the thermal weld point 110 shown in Figures 1 IB and 1 IC, as previously described.
- the kit can additionally comprise a sewing ring attached to the tissue mounting frame and elastomeric sheath.
- the sewing ring is also covered with DACRON and is attached to the tissue mounting frame and elastomeric sheath by welding the six DACRON layers together in a thermal weld point 110, as previously described.
- Preparation of the Autologous Tissue Leaflets 50 The general shape of each tissue leaflet 50 is shown in Figure 7A. The shape has been designed to form a cusp shape and to minimize tissue stress.
- the length of tissue along the tissue cusp line 94 is slightly greater than the cusp line length 30 of the tissue frame, as shown in Figure 2B, so that the extra tissue can form a cup shape, a process not dissimilar from that used to form the bust in ladies dresses. Although there is more tissue than required for the cusp length, it is not sufficient to cause folds or wrinkles in the tissue.
- tissue leaflets are typically cut with a tissue cutting die configured to both the size of the ultimate valve and also to provide for additional tissue on one side of the leaflet.
- cutting dies suitable for cutting predetermined shapes in autologous tissue are shown and described in U.S. Patent Nos. 5,163,955 and 5,425,741.
- disposable tissue cutting dies will be supplied and used in a housing which may be non-disposable.
- the cutting die is configured so that the tissue leaflets 50 are cut in a manner to take account of the extra tissue required for the overlap on the commissure posts 14 as shown in Figure 1 IB.
- the radius along the coaptation line of the leaflet whose tissue, at the commissure post, is on top of the adjacent leaflet (leaflet 50a in Figure 11B) is lengthened by the extra amount needed to overlay the inner leaflet.
- the tissue cutting die or other cutting device is configured to provide for this extra tissue on one side of the leaflet and also chamfer one corner of the cut leaflet to identify which leaflet is placed on top of the preceding leaflet.
- the tissue leaflet chamfer 66 is shown in Figure 7A.
- the radius along the coaptation line of the leaflet whose tissue is on top of the adjacent leaflet is lengthened by the extra amount needed to overlay the inner leaflet.
- the extra tissue, as measured from the centerline of the tissue leaflet, is shown as the crosshatched area 98 in Figure 7B.
- tissue cutting die In addition to the tissue cutting die, other intra-operative techniques can be employed to precisely cut the tissue leaflets, examples being water jet or laser cutting apparatus.
- a feature of the preferred embodiment of the invention is that it does not require a horizontal coaptation line. As shown in Figure 13, such a horizontal coaptation line 104 significantly increases the stress in the tissue at the commissure post 14. This is analogous to the tension required to hold a washing line very taut compared to a line which is allowed to have a degree of curvature.
- the outer elastomeric sheath 42 holds the tissue leaflets 50a and 50b around the commissure post 14 of the tissue mounting frame 40.
- the tissue length along the coaptation line is more than twice the radius of the valve. Taking account of tissue stretch, this extra tissue results in a coaptation to commissure post angle of approximately 65 degrees labeled as 102 in Figure 13. This reduced coaptation angle ⁇ greatly reduces the stress in the tissue leaflets at the commissure post 14.
- the tissue for constructing the tissue leaflets 50 is preferably autogenous tissue, such as pericardial tissue, but it may also be fascia lata, rectus fascia, or vein tissue. These tissue sources are all relatively flimsy and difficult to handle. This is because, once harvested, the tissue will have a thickness of about 10-12 mils. By comparison, bovine pericardium is about 15-20 mils thick. After the tissue is harvested, it is usually partially fixed by immersion in 0.625% glutaraldehyde solution for approximately 10 minutes. This both toughens the tissue and makes it easier to handle.
- tissue sources besides autogenous tissue are, of course, possible, such as bovine pericardium or other xenograft tissue or the like. Further, homograft tissue is possible. These tissues could be pre-cut by the valve builder or manufacturer outside the operating room and stored via conventional methods. If other tissue sources are used, however, the dimensions of the components would be adjusted to accommodate the tissue, which is generally thicker than the preferred tissue sources.
- the three separate leaflets 50 are cut, as described above.
- the three leaflets, the dimensions of which allow for overlap with the cropped corner 66 ( Figure 7A) are placed on top of the preceding leaflets.
- the leaflets are placed sequentially on the tissue anchor hooks 34, 36 in the cloth covered tissue mounting frame 40.
- the elastomeric sheath 42 is then folded or rolled-up over the frame 40 and the mounted tissue leaflets so that the concave pocket 84 situated at the top of each elastomeric sheath commissure post section 46 of the sheath 42 is hooked over a commissure post 14 of the tissue mounting frame 40.
- the DACRON covered elastomeric sheath rests gently on the tissue leaflets around the cusp line (see Figure 11C) such that the tissue leaflets form the naturally closed valve shown in Figure 1.
- Sheath 42 prevents the tissue leaflets 50 from coming off the tissue anchor hooks 34, 36, and the sheath substantially encloses and "hugs" the upper portion of the commissure posts 14 and the tissue leaflets attached thereto, as shown in Figure IOC, so that the adjacent leaflets touch each other in the coaptation line.
Abstract
Description
Claims
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP99949797A EP1117354A1 (en) | 1998-09-28 | 1999-09-22 | Heart valve having tissue retention with anchors and an outer sheath |
AU62594/99A AU6259499A (en) | 1998-09-28 | 1999-09-22 | Heart valve having tissue retention with anchors and an outer sheath |
JP2000571856A JP2002525169A (en) | 1998-09-28 | 1999-09-22 | Heart valve with tissue and outer sheath secured by anchor |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/161,809 US6334873B1 (en) | 1998-09-28 | 1998-09-28 | Heart valve having tissue retention with anchors and an outer sheath |
US09/161,809 | 1998-09-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2000018333A1 true WO2000018333A1 (en) | 2000-04-06 |
Family
ID=22582838
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1999/021997 WO2000018333A1 (en) | 1998-09-28 | 1999-09-22 | Heart valve having tissue retention with anchors and an outer sheath |
Country Status (6)
Country | Link |
---|---|
US (2) | US6334873B1 (en) |
EP (1) | EP1117354A1 (en) |
JP (1) | JP2002525169A (en) |
CN (1) | CN1328436A (en) |
AU (1) | AU6259499A (en) |
WO (1) | WO2000018333A1 (en) |
Cited By (165)
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WO2001064137A1 (en) * | 2000-02-28 | 2001-09-07 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Anchoring system for implantable heart valve prostheses |
JP2004531355A (en) * | 2001-07-03 | 2004-10-14 | アドヴァンスド バイオ プロスセティック サーフェシーズ リミテッド | Valve prosthesis having metal or pseudo-metal structure and method of manufacture |
WO2008133852A1 (en) * | 2007-04-26 | 2008-11-06 | St. Jude Medical, Inc. | Techniques for attaching flexible leaflets of prosthetic heart valves to supporting structures |
WO2009149462A3 (en) * | 2008-06-06 | 2010-02-04 | Edwards Lifesciences Corporation | Low profile transcatheter heart valve |
US8206438B2 (en) | 2001-03-23 | 2012-06-26 | Edwards Lifesciences Corporation | Prosthetic heart valve having flared outflow section |
US8206437B2 (en) | 2001-08-03 | 2012-06-26 | Philipp Bonhoeffer | Implant implantation unit and procedure for implanting the unit |
US8221493B2 (en) | 1999-12-31 | 2012-07-17 | Abps Venture One, Ltd. | Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof |
US8568475B2 (en) | 2010-10-05 | 2013-10-29 | Edwards Lifesciences Corporation | Spiraled commissure attachment for prosthetic valve |
EP2726024A1 (en) * | 2011-06-30 | 2014-05-07 | Edwards Lifesciences Corporation | Systems, dies, and methods for processing pericardial tissue |
US8795357B2 (en) | 2011-07-15 | 2014-08-05 | Edwards Lifesciences Corporation | Perivalvular sealing for transcatheter heart valve |
USRE45130E1 (en) | 2000-02-28 | 2014-09-09 | Jenavalve Technology Gmbh | Device for fastening and anchoring cardiac valve prostheses |
US8926691B2 (en) | 2009-12-04 | 2015-01-06 | Edwards Lifesciences Corporation | Apparatus for treating a mitral valve |
US9028545B2 (en) | 2005-06-13 | 2015-05-12 | Edwards Lifesciences Corporation | Method of delivering a prosthetic heart valve |
US9078749B2 (en) | 2007-09-13 | 2015-07-14 | Georg Lutter | Truncated cone heart valve stent |
US9095432B2 (en) | 1996-12-31 | 2015-08-04 | Edwards Lifesciences Pvt, Inc. | Collapsible prosthetic valve having an internal cover |
US9114008B2 (en) | 2006-12-22 | 2015-08-25 | Edwards Lifesciences Corporation | Implantable prosthetic valve assembly and method for making the same |
US9119716B2 (en) | 2011-07-27 | 2015-09-01 | Edwards Lifesciences Corporation | Delivery systems for prosthetic heart valve |
US9132006B2 (en) | 2001-10-11 | 2015-09-15 | Edwards Lifesciences Pvt, Inc. | Prosthetic heart valve and method |
US9155619B2 (en) | 2011-02-25 | 2015-10-13 | Edwards Lifesciences Corporation | Prosthetic heart valve delivery apparatus |
US9168131B2 (en) | 2011-12-09 | 2015-10-27 | Edwards Lifesciences Corporation | Prosthetic heart valve having improved commissure supports |
US9168129B2 (en) | 2013-02-12 | 2015-10-27 | Edwards Lifesciences Corporation | Artificial heart valve with scalloped frame design |
US9168136B2 (en) | 2001-09-13 | 2015-10-27 | Edwards Lifesciences Corporation | Methods for deploying self-expanding heart valves |
US9180005B1 (en) | 2014-07-17 | 2015-11-10 | Millipede, Inc. | Adjustable endolumenal mitral valve ring |
US9192471B2 (en) | 2007-01-08 | 2015-11-24 | Millipede, Inc. | Device for translumenal reshaping of a mitral valve annulus |
US9241792B2 (en) | 2008-02-29 | 2016-01-26 | Edwards Lifesciences Corporation | Two-step heart valve implantation |
US9241793B2 (en) | 2003-10-02 | 2016-01-26 | Edwards Lifesciences Corporation | Method of implanting a prosthetic aortic valve having non-laminar flow |
US9289282B2 (en) | 2011-05-31 | 2016-03-22 | Edwards Lifesciences Corporation | System and method for treating valve insufficiency or vessel dilatation |
US9301840B2 (en) | 2008-10-10 | 2016-04-05 | Edwards Lifesciences Corporation | Expandable introducer sheath |
US9326853B2 (en) | 2010-07-23 | 2016-05-03 | Edwards Lifesciences Corporation | Retaining mechanisms for prosthetic valves |
US9364325B2 (en) | 2008-08-22 | 2016-06-14 | Edwards Lifesciences Corporation | Prosthetic heart valve delivery system and method |
WO2016100913A1 (en) * | 2014-12-18 | 2016-06-23 | W.L. Gore & Associates, Inc. | Prosthetic valves with mechanically coupled leaflets |
US9375312B2 (en) | 2010-07-09 | 2016-06-28 | Highlife Sas | Transcatheter atrio-ventricular valve prosthesis |
US9393110B2 (en) | 2010-10-05 | 2016-07-19 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US9414918B2 (en) | 2012-09-06 | 2016-08-16 | Edwards Lifesciences Corporation | Heart valve sealing devices |
US9439763B2 (en) | 2013-02-04 | 2016-09-13 | Edwards Lifesciences Corporation | Prosthetic valve for replacing mitral valve |
US9480559B2 (en) | 2011-08-11 | 2016-11-01 | Tendyne Holdings, Inc. | Prosthetic valves and related inventions |
US9486306B2 (en) | 2013-04-02 | 2016-11-08 | Tendyne Holdings, Inc. | Inflatable annular sealing device for prosthetic mitral valve |
US9510947B2 (en) | 2011-10-21 | 2016-12-06 | Jenavalve Technology, Inc. | Catheter system for introducing an expandable heart valve stent into the body of a patient |
US9526611B2 (en) | 2013-10-29 | 2016-12-27 | Tendyne Holdings, Inc. | Apparatus and methods for delivery of transcatheter prosthetic valves |
US9532870B2 (en) | 2014-06-06 | 2017-01-03 | Edwards Lifesciences Corporation | Prosthetic valve for replacing a mitral valve |
US9561101B2 (en) | 2008-06-20 | 2017-02-07 | Edwards Lifesciences Corporation | Two-part prosthetic valve system |
US9597181B2 (en) | 2013-06-25 | 2017-03-21 | Tendyne Holdings, Inc. | Thrombus management and structural compliance features for prosthetic heart valves |
US9610159B2 (en) | 2013-05-30 | 2017-04-04 | Tendyne Holdings, Inc. | Structural members for prosthetic mitral valves |
US9622863B2 (en) | 2013-11-22 | 2017-04-18 | Edwards Lifesciences Corporation | Aortic insufficiency repair device and method |
US9636221B2 (en) | 2007-09-26 | 2017-05-02 | St. Jude Medical, Inc. | Collapsible prosthetic heart valves |
US9675449B2 (en) | 2008-07-15 | 2017-06-13 | St. Jude Medical, Llc | Collapsible and re-expandable prosthetic heart valve cuff designs and complementary technological applications |
US9675454B2 (en) | 2012-07-30 | 2017-06-13 | Tendyne Holdings, Inc. | Delivery systems and methods for transcatheter prosthetic valves |
US9795480B2 (en) | 2010-08-24 | 2017-10-24 | Millipede, Inc. | Reconfiguring tissue features of a heart annulus |
US9820851B2 (en) | 2007-09-28 | 2017-11-21 | St. Jude Medical, Llc | Collapsible-expandable prosthetic heart valves with structures for clamping native tissue |
US9827092B2 (en) | 2011-12-16 | 2017-11-28 | Tendyne Holdings, Inc. | Tethers for prosthetic mitral valve |
US9848983B2 (en) | 2015-02-13 | 2017-12-26 | Millipede, Inc. | Valve replacement using rotational anchors |
US9855141B2 (en) | 2014-12-18 | 2018-01-02 | W. L. Gore & Associates, Inc. | Prosthetic valves with mechanically coupled leaflets |
US9867700B2 (en) | 2013-05-20 | 2018-01-16 | Edwards Lifesciences Corporation | Prosthetic heart valve delivery apparatus |
US9867694B2 (en) | 2013-08-30 | 2018-01-16 | Jenavalve Technology Inc. | Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame |
US9878127B2 (en) | 2012-05-16 | 2018-01-30 | Jenavalve Technology, Inc. | Catheter delivery system for heart valve prosthesis |
US9895221B2 (en) | 2012-07-28 | 2018-02-20 | Tendyne Holdings, Inc. | Multi-component designs for heart valve retrieval device, sealing structures and stent assembly |
US9913715B2 (en) | 2013-11-06 | 2018-03-13 | St. Jude Medical, Cardiology Division, Inc. | Paravalvular leak sealing mechanism |
US9986993B2 (en) | 2014-02-11 | 2018-06-05 | Tendyne Holdings, Inc. | Adjustable tether and epicardial pad system for prosthetic heart valve |
US10010417B2 (en) | 2015-04-16 | 2018-07-03 | Edwards Lifesciences Corporation | Low-profile prosthetic heart valve for replacing a mitral valve |
US10016276B2 (en) | 2012-11-21 | 2018-07-10 | Edwards Lifesciences Corporation | Retaining mechanisms for prosthetic heart valves |
US10022220B2 (en) | 2000-04-06 | 2018-07-17 | Edwards Lifesciences Corporation | Methods of implanting minimally-invasive prosthetic heart valves |
US10058424B2 (en) | 2014-08-21 | 2018-08-28 | Edwards Lifesciences Corporation | Dual-flange prosthetic valve frame |
US10064718B2 (en) | 2015-04-16 | 2018-09-04 | Edwards Lifesciences Corporation | Low-profile prosthetic heart valve for replacing a mitral valve |
US10076412B2 (en) | 2008-02-29 | 2018-09-18 | Edwards Lifesciences Corporation | Expandable member for deploying a prosthetic device |
US10098734B2 (en) | 2013-12-05 | 2018-10-16 | Edwards Lifesciences Corporation | Prosthetic heart valve and delivery apparatus |
US10179043B2 (en) | 2016-02-12 | 2019-01-15 | Edwards Lifesciences Corporation | Prosthetic heart valve having multi-level sealing member |
US10195026B2 (en) | 2014-07-22 | 2019-02-05 | Edwards Lifesciences Corporation | Mitral valve anchoring |
US10201419B2 (en) | 2014-02-05 | 2019-02-12 | Tendyne Holdings, Inc. | Apparatus and methods for transfemoral delivery of prosthetic mitral valve |
US10238514B2 (en) | 2011-10-21 | 2019-03-26 | Edwards Lifesciences Cardiaq Llc | Actively controllable stent, stent graft, heart valve and method of controlling same |
WO2019089163A1 (en) * | 2017-10-31 | 2019-05-09 | W. L. Gore & Associates, Inc. | Jacket for surgical heart valve |
US10314697B2 (en) | 2014-08-18 | 2019-06-11 | W. L. Gore & Associates, Inc. | Frame with integral sewing cuff for prosthetic valves |
US10327894B2 (en) | 2015-09-18 | 2019-06-25 | Tendyne Holdings, Inc. | Methods for delivery of prosthetic mitral valves |
US10327896B2 (en) | 2015-04-10 | 2019-06-25 | Edwards Lifesciences Corporation | Expandable sheath with elastomeric cross sectional portions |
US10335275B2 (en) | 2015-09-29 | 2019-07-02 | Millipede, Inc. | Methods for delivery of heart valve devices using intravascular ultrasound imaging |
US10342659B2 (en) | 2014-09-15 | 2019-07-09 | W. L. Gore & Associates, Inc. | Prosthetic heart valve with retention elements |
US10368984B2 (en) | 2013-12-06 | 2019-08-06 | W. L. Gore & Associates, Inc. | Asymmetric opening and closing prosthetic valve leaflet |
US10376364B2 (en) | 2015-11-10 | 2019-08-13 | Edwards Lifesciences Corporation | Implant delivery capsule |
US10413406B2 (en) | 2007-12-14 | 2019-09-17 | Edwards Lifesciences Corporation | Leaflet attachment frame for a prosthetic valve |
US10463494B2 (en) | 2013-04-02 | 2019-11-05 | Tendyne Holdings, Inc. | Prosthetic heart valve and systems and methods for delivering the same |
US10463489B2 (en) | 2013-04-02 | 2019-11-05 | Tendyne Holdings, Inc. | Prosthetic heart valve and systems and methods for delivering the same |
US10463478B2 (en) | 2012-12-19 | 2019-11-05 | W. L. Gore & Associates, Inc. | Truncated leaflet for prosthetic heart valves |
US10463484B2 (en) | 2016-11-17 | 2019-11-05 | Edwards Lifesciences Corporation | Prosthetic heart valve having leaflet inflow below frame |
US10470877B2 (en) | 2016-05-03 | 2019-11-12 | Tendyne Holdings, Inc. | Apparatus and methods for anterior valve leaflet management |
US10470876B2 (en) | 2015-11-10 | 2019-11-12 | Edwards Lifesciences Corporation | Transcatheter heart valve for replacing natural mitral valve |
US10478293B2 (en) | 2013-04-04 | 2019-11-19 | Tendyne Holdings, Inc. | Retrieval and repositioning system for prosthetic heart valve |
US10478295B2 (en) | 2011-10-21 | 2019-11-19 | Edwards Lifesciences Cardiaq Llc | Actively controllable stent, stent graft, heart valve and method of controlling same |
US10507097B2 (en) | 2006-07-31 | 2019-12-17 | Edwards Lifesciences Cardiaq Llc | Surgical implant devices and methods for their manufacture and use |
US10517722B2 (en) | 2016-03-24 | 2019-12-31 | Edwards Lifesciences Corporation | Delivery system for prosthetic heart valve |
US10517728B2 (en) | 2014-03-10 | 2019-12-31 | Tendyne Holdings, Inc. | Devices and methods for positioning and monitoring tether load for prosthetic mitral valve |
US10543088B2 (en) | 2012-09-14 | 2020-01-28 | Boston Scientific Scimed, Inc. | Mitral valve inversion prostheses |
US10548731B2 (en) | 2017-02-10 | 2020-02-04 | Boston Scientific Scimed, Inc. | Implantable device and delivery system for reshaping a heart valve annulus |
US10555718B2 (en) | 2013-10-17 | 2020-02-11 | Tendyne Holdings, Inc. | Apparatus and methods for alignment and deployment of intracardiac devices |
US10555813B2 (en) | 2015-11-17 | 2020-02-11 | Boston Scientific Scimed, Inc. | Implantable device and delivery system for reshaping a heart valve annulus |
US10568732B2 (en) | 2009-07-02 | 2020-02-25 | Edwards Lifesciences Cardiaq Llc | Surgical implant devices and methods for their manufacture and use |
US10603165B2 (en) | 2016-12-06 | 2020-03-31 | Edwards Lifesciences Corporation | Mechanically expanding heart valve and delivery apparatus therefor |
US10610358B2 (en) | 2015-12-28 | 2020-04-07 | Tendyne Holdings, Inc. | Atrial pocket closures for prosthetic heart valves |
US10610356B2 (en) | 2015-02-05 | 2020-04-07 | Tendyne Holdings, Inc. | Expandable epicardial pads and devices and methods for delivery of same |
US10610354B2 (en) | 2013-08-01 | 2020-04-07 | Tendyne Holdings, Inc. | Epicardial anchor devices and methods |
US10617520B2 (en) | 2008-05-01 | 2020-04-14 | Edwards Lifesciences Corporation | Method of replacing mitral valve |
US10639144B2 (en) | 2012-12-19 | 2020-05-05 | W. L. Gore & Associates, Inc. | Vertical coaptation zone in a planar portion of prosthetic heart valve leaflet |
US10660745B2 (en) | 2012-12-19 | 2020-05-26 | W. L. Gore & Associates, Inc. | Methods for improved prosthetic heart valve with leaflet shelving |
US10667905B2 (en) | 2015-04-16 | 2020-06-02 | Tendyne Holdings, Inc. | Apparatus and methods for delivery, repositioning, and retrieval of transcatheter prosthetic valves |
US10687968B2 (en) | 2006-07-31 | 2020-06-23 | Edwards Lifesciences Cardiaq Llc | Sealable endovascular implants and methods for their use |
US10709555B2 (en) | 2015-05-01 | 2020-07-14 | Jenavalve Technology, Inc. | Device and method with reduced pacemaker rate in heart valve replacement |
US10722353B2 (en) | 2017-08-21 | 2020-07-28 | Edwards Lifesciences Corporation | Sealing member for prosthetic heart valve |
US10786351B2 (en) | 2015-01-07 | 2020-09-29 | Tendyne Holdings, Inc. | Prosthetic mitral valves and apparatus and methods for delivery of same |
US10792471B2 (en) | 2015-04-10 | 2020-10-06 | Edwards Lifesciences Corporation | Expandable sheath |
US10849755B2 (en) | 2012-09-14 | 2020-12-01 | Boston Scientific Scimed, Inc. | Mitral valve inversion prostheses |
US10869759B2 (en) | 2017-06-05 | 2020-12-22 | Edwards Lifesciences Corporation | Mechanically expandable heart valve |
US10874508B2 (en) | 2011-10-21 | 2020-12-29 | Edwards Lifesciences Cardiaq Llc | Actively controllable stent, stent graft, heart valve and method of controlling same |
US10881507B2 (en) | 2012-12-19 | 2021-01-05 | W. L. Gore & Associates, Inc. | Prosthetic valves, frames and leaflets and methods thereof |
US10898319B2 (en) | 2017-08-17 | 2021-01-26 | Edwards Lifesciences Corporation | Sealing member for prosthetic heart valve |
US10918473B2 (en) | 2017-07-18 | 2021-02-16 | Edwards Lifesciences Corporation | Transcatheter heart valve storage container and crimping mechanism |
US10932903B2 (en) | 2017-08-15 | 2021-03-02 | Edwards Lifesciences Corporation | Skirt assembly for implantable prosthetic valve |
US10959842B2 (en) | 2017-09-12 | 2021-03-30 | W. L. Gore & Associates, Inc. | Leaflet frame attachment for prosthetic valves |
US10966820B2 (en) | 2012-12-19 | 2021-04-06 | W. L. Gore & Associates, Inc. | Geometric control of bending character in prosthetic heart valve leaflets |
US10973631B2 (en) | 2016-11-17 | 2021-04-13 | Edwards Lifesciences Corporation | Crimping accessory device for a prosthetic valve |
US10973629B2 (en) | 2017-09-06 | 2021-04-13 | Edwards Lifesciences Corporation | Sealing member for prosthetic heart valve |
US10987218B2 (en) | 2017-10-31 | 2021-04-27 | W. L. Gore & Associates, Inc. | Transcatheter deployment systems and associated methods |
US10993805B2 (en) | 2008-02-26 | 2021-05-04 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US11013600B2 (en) | 2017-01-23 | 2021-05-25 | Edwards Lifesciences Corporation | Covered prosthetic heart valve |
US11013595B2 (en) | 2017-08-11 | 2021-05-25 | Edwards Lifesciences Corporation | Sealing element for prosthetic heart valve |
US11020221B2 (en) | 2017-09-27 | 2021-06-01 | W. L. Gore & Associates, Inc. | Prosthetic valve with expandable frame and associated systems and methods |
US11026781B2 (en) | 2017-05-22 | 2021-06-08 | Edwards Lifesciences Corporation | Valve anchor and installation method |
US11026785B2 (en) | 2017-06-05 | 2021-06-08 | Edwards Lifesciences Corporation | Mechanically expandable heart valve |
US11039921B2 (en) | 2016-06-13 | 2021-06-22 | Tendyne Holdings, Inc. | Sequential delivery of two-part prosthetic mitral valve |
US11039917B2 (en) | 2012-12-19 | 2021-06-22 | W. L. Gore & Associates, Inc. | Geometric prosthetic heart valves |
US11065138B2 (en) | 2016-05-13 | 2021-07-20 | Jenavalve Technology, Inc. | Heart valve prosthesis delivery system and method for delivery of heart valve prosthesis with introducer sheath and loading system |
US11065116B2 (en) | 2016-07-12 | 2021-07-20 | Tendyne Holdings, Inc. | Apparatus and methods for trans-septal retrieval of prosthetic heart valves |
USD926322S1 (en) | 2018-11-07 | 2021-07-27 | W. L. Gore & Associates, Inc. | Heart valve cover |
US11083575B2 (en) | 2017-08-14 | 2021-08-10 | Edwards Lifesciences Corporation | Heart valve frame design with non-uniform struts |
US11090153B2 (en) | 2017-10-13 | 2021-08-17 | W. L. Gore & Associates, Inc. | Telescoping prosthetic valve and delivery system |
US11090157B2 (en) | 2016-06-30 | 2021-08-17 | Tendyne Holdings, Inc. | Prosthetic heart valves and apparatus and methods for delivery of same |
US11096782B2 (en) | 2015-12-03 | 2021-08-24 | Tendyne Holdings, Inc. | Frame features for prosthetic mitral valves |
US11096781B2 (en) | 2016-08-01 | 2021-08-24 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US11109963B2 (en) | 2017-09-27 | 2021-09-07 | W. L. Gore & Associates, Inc. | Prosthetic valves with mechanically coupled leaflets |
US11123183B2 (en) | 2017-10-31 | 2021-09-21 | W. L. Gore & Associates, Inc. | Prosthetic heart valve |
US11135056B2 (en) | 2017-05-15 | 2021-10-05 | Edwards Lifesciences Corporation | Devices and methods of commissure formation for prosthetic heart valve |
US11147667B2 (en) | 2017-09-08 | 2021-10-19 | Edwards Lifesciences Corporation | Sealing member for prosthetic heart valve |
US11154399B2 (en) | 2017-07-13 | 2021-10-26 | Tendyne Holdings, Inc. | Prosthetic heart valves and apparatus and methods for delivery of same |
US11166809B2 (en) | 2012-07-25 | 2021-11-09 | W. L. Gore & Associates, Inc. | Everting transcatheter valve and methods |
US11179236B2 (en) | 2009-12-08 | 2021-11-23 | Colorado State University Research Foundation | Device and system for transcatheter mitral valve replacement |
US11185406B2 (en) | 2017-01-23 | 2021-11-30 | Edwards Lifesciences Corporation | Covered prosthetic heart valve |
US11191639B2 (en) | 2017-08-28 | 2021-12-07 | Tendyne Holdings, Inc. | Prosthetic heart valves with tether coupling features |
US11197754B2 (en) | 2017-01-27 | 2021-12-14 | Jenavalve Technology, Inc. | Heart valve mimicry |
US11224510B2 (en) | 2013-04-02 | 2022-01-18 | Tendyne Holdings, Inc. | Prosthetic heart valve and systems and methods for delivering the same |
US11318011B2 (en) | 2018-04-27 | 2022-05-03 | Edwards Lifesciences Corporation | Mechanically expandable heart valve with leaflet clamps |
US11357624B2 (en) | 2007-04-13 | 2022-06-14 | Jenavalve Technology, Inc. | Medical device for treating a heart valve insufficiency |
US11395751B2 (en) | 2013-11-11 | 2022-07-26 | Edwards Lifesciences Cardiaq Llc | Systems and methods for manufacturing a stent frame |
US11399932B2 (en) | 2019-03-26 | 2022-08-02 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US11406493B2 (en) | 2014-09-12 | 2022-08-09 | Mitral Valve Technologies Sarl | Mitral repair and replacement devices and methods |
US11439502B2 (en) | 2017-10-31 | 2022-09-13 | W. L. Gore & Associates, Inc. | Medical valve and leaflet promoting tissue ingrowth |
US11446141B2 (en) | 2018-10-19 | 2022-09-20 | Edwards Lifesciences Corporation | Prosthetic heart valve having non-cylindrical frame |
US11497601B2 (en) | 2019-03-01 | 2022-11-15 | W. L. Gore & Associates, Inc. | Telescoping prosthetic valve with retention element |
US11517431B2 (en) | 2005-01-20 | 2022-12-06 | Jenavalve Technology, Inc. | Catheter system for implantation of prosthetic heart valves |
US11564794B2 (en) | 2008-02-26 | 2023-01-31 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US11589981B2 (en) | 2010-05-25 | 2023-02-28 | Jenavalve Technology, Inc. | Prosthetic heart valve and transcatheter delivered endoprosthesis comprising a prosthetic heart valve and a stent |
US11648110B2 (en) | 2019-12-05 | 2023-05-16 | Tendyne Holdings, Inc. | Braided anchor for mitral valve |
US11648114B2 (en) | 2019-12-20 | 2023-05-16 | Tendyne Holdings, Inc. | Distally loaded sheath and loading funnel |
US11654023B2 (en) | 2017-01-23 | 2023-05-23 | Edwards Lifesciences Corporation | Covered prosthetic heart valve |
US11678980B2 (en) | 2020-08-19 | 2023-06-20 | Tendyne Holdings, Inc. | Fully-transseptal apical pad with pulley for tensioning |
US11730589B2 (en) | 2010-03-05 | 2023-08-22 | Edwards Lifesciences Corporation | Prosthetic heart valve having an inner frame and an outer frame |
US11857411B2 (en) | 2017-08-18 | 2024-01-02 | Edwards Lifesciences Corporation | Pericardial sealing member for prosthetic heart valve |
US11883281B2 (en) | 2017-05-31 | 2024-01-30 | Edwards Lifesciences Corporation | Sealing member for prosthetic heart valve |
US11951003B2 (en) | 2021-06-04 | 2024-04-09 | Edwards Lifesciences Corporation | Mechanically expandable heart valve |
Families Citing this family (130)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6736845B2 (en) * | 1999-01-26 | 2004-05-18 | Edwards Lifesciences Corporation | Holder for flexible heart valve |
EP1173116A2 (en) * | 1999-04-28 | 2002-01-23 | St. Jude Medical, Inc. | Heart valve prostheses |
US6991643B2 (en) | 2000-12-20 | 2006-01-31 | Usgi Medical Inc. | Multi-barbed device for retaining tissue in apposition and methods of use |
US6626899B2 (en) * | 1999-06-25 | 2003-09-30 | Nidus Medical, Llc | Apparatus and methods for treating tissue |
US6709457B1 (en) * | 1999-11-24 | 2004-03-23 | St. Jude Medical, Inc. | Attachment of suture cuff to prosthetic heart valve |
US6872226B2 (en) * | 2001-01-29 | 2005-03-29 | 3F Therapeutics, Inc. | Method of cutting material for use in implantable medical device |
US8366769B2 (en) | 2000-06-01 | 2013-02-05 | Edwards Lifesciences Corporation | Low-profile, pivotable heart valve sewing ring |
US6409758B2 (en) * | 2000-07-27 | 2002-06-25 | Edwards Lifesciences Corporation | Heart valve holder for constricting the valve commissures and methods of use |
US7097659B2 (en) * | 2001-09-07 | 2006-08-29 | Medtronic, Inc. | Fixation band for affixing a prosthetic heart valve to tissue |
US7201771B2 (en) * | 2001-12-27 | 2007-04-10 | Arbor Surgical Technologies, Inc. | Bioprosthetic heart valve |
US8308797B2 (en) | 2002-01-04 | 2012-11-13 | Colibri Heart Valve, LLC | Percutaneously implantable replacement heart valve device and method of making same |
US6752828B2 (en) * | 2002-04-03 | 2004-06-22 | Scimed Life Systems, Inc. | Artificial valve |
AU2003234505A1 (en) * | 2002-05-03 | 2003-11-17 | The General Hospital Corporation | Involuted endovascular valve and method of construction |
US8348963B2 (en) * | 2002-07-03 | 2013-01-08 | Hlt, Inc. | Leaflet reinforcement for regurgitant valves |
US7959674B2 (en) * | 2002-07-16 | 2011-06-14 | Medtronic, Inc. | Suture locking assembly and method of use |
US7217287B2 (en) * | 2002-08-28 | 2007-05-15 | Heart Leaflet Technologies, Inc. | Method of treating diseased valve |
FR2846639B1 (en) * | 2002-11-06 | 2004-12-10 | Innovation Packaging | PACKAGING AND DISPENSING DEVICE FOR A LIQUID OR SEMI-LIQUID PRODUCT |
JP2006505363A (en) | 2002-11-07 | 2006-02-16 | アクシオム メディカル インク. | Epicardial heart wire, thorax tube integrated with epicardial heart wire, and method of use thereof |
US8551162B2 (en) | 2002-12-20 | 2013-10-08 | Medtronic, Inc. | Biologically implantable prosthesis |
US8021421B2 (en) | 2003-08-22 | 2011-09-20 | Medtronic, Inc. | Prosthesis heart valve fixturing device |
US7556647B2 (en) * | 2003-10-08 | 2009-07-07 | Arbor Surgical Technologies, Inc. | Attachment device and methods of using the same |
US8128681B2 (en) | 2003-12-19 | 2012-03-06 | Boston Scientific Scimed, Inc. | Venous valve apparatus, system, and method |
US7871435B2 (en) | 2004-01-23 | 2011-01-18 | Edwards Lifesciences Corporation | Anatomically approximate prosthetic mitral heart valve |
US7976539B2 (en) * | 2004-03-05 | 2011-07-12 | Hansen Medical, Inc. | System and method for denaturing and fixing collagenous tissue |
US20050228494A1 (en) * | 2004-03-29 | 2005-10-13 | Salvador Marquez | Controlled separation heart valve frame |
WO2005096988A1 (en) * | 2004-04-01 | 2005-10-20 | Cook Incorporated | A device for retracting the walls of a body vessel with remodelable material |
EP1737390A1 (en) * | 2004-04-08 | 2007-01-03 | Cook Incorporated | Implantable medical device with optimized shape |
US7850704B2 (en) * | 2004-09-27 | 2010-12-14 | Theranova, Llc | Method and apparatus for anchoring implants |
US20090030435A1 (en) * | 2004-09-27 | 2009-01-29 | Theranova, Llc | Method and apparatus for anchoring cardiovascular implants |
US7989157B2 (en) * | 2005-01-11 | 2011-08-02 | Medtronic, Inc. | Solution for storing bioprosthetic tissue used in a biological prosthesis |
US8574257B2 (en) * | 2005-02-10 | 2013-11-05 | Edwards Lifesciences Corporation | System, device, and method for providing access in a cardiovascular environment |
US7513909B2 (en) * | 2005-04-08 | 2009-04-07 | Arbor Surgical Technologies, Inc. | Two-piece prosthetic valves with snap-in connection and methods for use |
US7722666B2 (en) * | 2005-04-15 | 2010-05-25 | Boston Scientific Scimed, Inc. | Valve apparatus, system and method |
CN101180010B (en) | 2005-05-24 | 2010-12-01 | 爱德华兹生命科学公司 | Rapid deployment prosthetic heart valve |
WO2006130505A2 (en) * | 2005-05-27 | 2006-12-07 | Arbor Surgical Technologies, Inc. | Gasket with collar for prosthetic heart valves and methods for using them |
US7238200B2 (en) * | 2005-06-03 | 2007-07-03 | Arbor Surgical Technologies, Inc. | Apparatus and methods for making leaflets and valve prostheses including such leaflets |
US7776084B2 (en) | 2005-07-13 | 2010-08-17 | Edwards Lifesciences Corporation | Prosthetic mitral heart valve having a contoured sewing ring |
US7632308B2 (en) * | 2005-11-23 | 2009-12-15 | Didier Loulmet | Methods, devices, and kits for treating mitral valve prolapse |
GB0524087D0 (en) * | 2005-11-25 | 2006-01-04 | Symetis Ag | Biodegradable scaffold |
US20070168022A1 (en) * | 2006-01-17 | 2007-07-19 | Eldridge Charles J | Heart valve |
US7967857B2 (en) | 2006-01-27 | 2011-06-28 | Medtronic, Inc. | Gasket with spring collar for prosthetic heart valves and methods for making and using them |
JP5102279B2 (en) * | 2006-03-10 | 2012-12-19 | メドトロニック,インコーポレイテッド | Artificial valve introducer, method for producing the same and method for using the same |
US8075615B2 (en) | 2006-03-28 | 2011-12-13 | Medtronic, Inc. | Prosthetic cardiac valve formed from pericardium material and methods of making same |
WO2007130881A2 (en) * | 2006-04-29 | 2007-11-15 | Arbor Surgical Technologies, Inc. | Multiple component prosthetic heart valve assemblies and apparatus and methods for delivering them |
US8021161B2 (en) * | 2006-05-01 | 2011-09-20 | Edwards Lifesciences Corporation | Simulated heart valve root for training and testing |
US8918193B2 (en) * | 2006-08-16 | 2014-12-23 | Vahe S. Yacoubian | Heart wire |
CN101626682B (en) | 2006-10-27 | 2014-04-16 | 爱德华兹生命科学公司 | Biological tissue for surgical implantation |
US9101691B2 (en) | 2007-06-11 | 2015-08-11 | Edwards Lifesciences Corporation | Methods for pre-stressing and capping bioprosthetic tissue |
WO2009023818A1 (en) * | 2007-08-15 | 2009-02-19 | Theranova, Llc | Method and apparatus for automated active sterilization of fully implanted devices |
US8454686B2 (en) * | 2007-09-28 | 2013-06-04 | St. Jude Medical, Inc. | Two-stage collapsible/expandable prosthetic heart valves and anchoring systems |
EP2211779B1 (en) | 2007-10-15 | 2014-08-20 | Edwards Lifesciences Corporation | Transcatheter heart valve with micro-anchors |
US7846199B2 (en) * | 2007-11-19 | 2010-12-07 | Cook Incorporated | Remodelable prosthetic valve |
US8357387B2 (en) | 2007-12-21 | 2013-01-22 | Edwards Lifesciences Corporation | Capping bioprosthetic tissue to reduce calcification |
US9603558B2 (en) | 2008-08-15 | 2017-03-28 | Theranova, Llc | Methods and devices for the diagnosis and treatment of diabetes |
US8449625B2 (en) * | 2009-10-27 | 2013-05-28 | Edwards Lifesciences Corporation | Methods of measuring heart valve annuluses for valve replacement |
CN102223910B (en) | 2008-11-25 | 2014-05-07 | 爱德华兹生命科学公司 | Apparatus for in situ expansion of prosthetic device |
US8308798B2 (en) | 2008-12-19 | 2012-11-13 | Edwards Lifesciences Corporation | Quick-connect prosthetic heart valve and methods |
US20110011917A1 (en) * | 2008-12-31 | 2011-01-20 | Hansen Medical, Inc. | Methods, devices, and kits for treating valve prolapse |
CN102438552A (en) * | 2009-03-19 | 2012-05-02 | 米利佩德有限责任公司 | Reconfiguring heart features |
US9980818B2 (en) | 2009-03-31 | 2018-05-29 | Edwards Lifesciences Corporation | Prosthetic heart valve system with positioning markers |
US8348998B2 (en) | 2009-06-26 | 2013-01-08 | Edwards Lifesciences Corporation | Unitary quick connect prosthetic heart valve and deployment system and methods |
GR1007028B (en) * | 2009-11-11 | 2010-10-22 | Ευσταθιος-Ανδρεας Αγαθος | SUPPORT OF BIO-ADDITIONAL VALVES WITH DIAGNOSTIC HEART SHAPE |
US8870950B2 (en) | 2009-12-08 | 2014-10-28 | Mitral Tech Ltd. | Rotation-based anchoring of an implant |
WO2011111047A2 (en) | 2010-03-10 | 2011-09-15 | Mitraltech Ltd. | Prosthetic mitral valve with tissue anchors |
CN102811681B (en) | 2010-03-23 | 2016-10-12 | 爱德华兹生命科学公司 | The method of regulation lamellar bioprosthetic tissue |
WO2011143238A2 (en) | 2010-05-10 | 2011-11-17 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US9554901B2 (en) | 2010-05-12 | 2017-01-31 | Edwards Lifesciences Corporation | Low gradient prosthetic heart valve |
CN103153384B (en) | 2010-06-28 | 2016-03-09 | 科利柏心脏瓣膜有限责任公司 | For the device of device in the delivery of vascular of chamber |
US11653910B2 (en) | 2010-07-21 | 2023-05-23 | Cardiovalve Ltd. | Helical anchor implantation |
US9763657B2 (en) | 2010-07-21 | 2017-09-19 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
US9370418B2 (en) | 2010-09-10 | 2016-06-21 | Edwards Lifesciences Corporation | Rapidly deployable surgical heart valves |
US8641757B2 (en) | 2010-09-10 | 2014-02-04 | Edwards Lifesciences Corporation | Systems for rapidly deploying surgical heart valves |
US9125741B2 (en) | 2010-09-10 | 2015-09-08 | Edwards Lifesciences Corporation | Systems and methods for ensuring safe and rapid deployment of prosthetic heart valves |
US8845720B2 (en) | 2010-09-27 | 2014-09-30 | Edwards Lifesciences Corporation | Prosthetic heart valve frame with flexible commissures |
US9737400B2 (en) | 2010-12-14 | 2017-08-22 | Colibri Heart Valve Llc | Percutaneously deliverable heart valve including folded membrane cusps with integral leaflets |
GB2488530A (en) * | 2011-02-18 | 2012-09-05 | David J Wheatley | Heart valve |
US8945209B2 (en) | 2011-05-20 | 2015-02-03 | Edwards Lifesciences Corporation | Encapsulated heart valve |
CA2841952C (en) | 2011-07-20 | 2018-07-03 | Boston Scientific Scimed, Inc. | Heart valve replacement |
US20140324164A1 (en) | 2011-08-05 | 2014-10-30 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
EP3417813B1 (en) | 2011-08-05 | 2020-05-13 | Cardiovalve Ltd | Percutaneous mitral valve replacement |
WO2013021374A2 (en) | 2011-08-05 | 2013-02-14 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
US8852272B2 (en) | 2011-08-05 | 2014-10-07 | Mitraltech Ltd. | Techniques for percutaneous mitral valve replacement and sealing |
US9078747B2 (en) | 2011-12-21 | 2015-07-14 | Edwards Lifesciences Corporation | Anchoring device for replacing or repairing a heart valve |
US9750595B2 (en) | 2012-09-28 | 2017-09-05 | Covidien Lp | Implantable medical devices which include grip-members and methods of use thereof |
US10238771B2 (en) | 2012-11-08 | 2019-03-26 | Edwards Lifesciences Corporation | Methods for treating bioprosthetic tissue using a nucleophile/electrophile in a catalytic system |
US8628571B1 (en) | 2012-11-13 | 2014-01-14 | Mitraltech Ltd. | Percutaneously-deliverable mechanical valve |
US20150351906A1 (en) | 2013-01-24 | 2015-12-10 | Mitraltech Ltd. | Ventricularly-anchored prosthetic valves |
US11007058B2 (en) | 2013-03-15 | 2021-05-18 | Edwards Lifesciences Corporation | Valved aortic conduits |
CN105142574B (en) | 2013-03-15 | 2017-12-01 | 爱德华兹生命科学公司 | Band valve sustainer pipeline |
US9468527B2 (en) | 2013-06-12 | 2016-10-18 | Edwards Lifesciences Corporation | Cardiac implant with integrated suture fasteners |
US9919137B2 (en) | 2013-08-28 | 2018-03-20 | Edwards Lifesciences Corporation | Integrated balloon catheter inflation system |
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US9615922B2 (en) | 2013-09-30 | 2017-04-11 | Edwards Lifesciences Corporation | Method and apparatus for preparing a contoured biological tissue |
US10959839B2 (en) | 2013-10-08 | 2021-03-30 | Edwards Lifesciences Corporation | Method for directing cellular migration patterns on a biological tissue |
US20150122687A1 (en) | 2013-11-06 | 2015-05-07 | Edwards Lifesciences Corporation | Bioprosthetic heart valves having adaptive seals to minimize paravalvular leakage |
US9549816B2 (en) | 2014-04-03 | 2017-01-24 | Edwards Lifesciences Corporation | Method for manufacturing high durability heart valve |
US9585752B2 (en) | 2014-04-30 | 2017-03-07 | Edwards Lifesciences Corporation | Holder and deployment system for surgical heart valves |
AU2015256601B2 (en) | 2014-05-09 | 2020-01-23 | Foldax, Inc. | Replacement heart valves and their methods of use and manufacture |
CA2914094C (en) | 2014-06-20 | 2021-01-05 | Edwards Lifesciences Corporation | Surgical heart valves identifiable post-implant |
USD867594S1 (en) | 2015-06-19 | 2019-11-19 | Edwards Lifesciences Corporation | Prosthetic heart valve |
EP4066786A1 (en) | 2014-07-30 | 2022-10-05 | Cardiovalve Ltd. | Articulatable prosthetic valve |
WO2016125160A1 (en) | 2015-02-05 | 2016-08-11 | Mitraltech Ltd. | Prosthetic valve with axially-sliding frames |
US9974651B2 (en) | 2015-02-05 | 2018-05-22 | Mitral Tech Ltd. | Prosthetic valve with axially-sliding frames |
WO2017004374A1 (en) | 2015-07-02 | 2017-01-05 | Edwards Lifesciences Corporation | Integrated hybrid heart valves |
WO2017004369A1 (en) | 2015-07-02 | 2017-01-05 | Edwards Lifesciences Corporation | Hybrid heart valves adapted for post-implant expansion |
CA2995855C (en) | 2015-09-02 | 2024-01-30 | Edwards Lifesciences Corporation | Spacer for securing a transcatheter valve to a bioprosthetic cardiac structure |
US10080653B2 (en) | 2015-09-10 | 2018-09-25 | Edwards Lifesciences Corporation | Limited expansion heart valve |
US10531866B2 (en) | 2016-02-16 | 2020-01-14 | Cardiovalve Ltd. | Techniques for providing a replacement valve and transseptal communication |
US10667904B2 (en) | 2016-03-08 | 2020-06-02 | Edwards Lifesciences Corporation | Valve implant with integrated sensor and transmitter |
US10456245B2 (en) | 2016-05-16 | 2019-10-29 | Edwards Lifesciences Corporation | System and method for applying material to a stent |
WO2018029680A1 (en) | 2016-08-10 | 2018-02-15 | Mitraltech Ltd. | Prosthetic valve with concentric frames |
AU2017347839A1 (en) | 2016-10-28 | 2018-11-15 | Foldax, Inc. | Prosthetic heart valves with elastic support structures and related methods |
USD846122S1 (en) | 2016-12-16 | 2019-04-16 | Edwards Lifesciences Corporation | Heart valve sizer |
US10463485B2 (en) | 2017-04-06 | 2019-11-05 | Edwards Lifesciences Corporation | Prosthetic valve holders with automatic deploying mechanisms |
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CA3065329A1 (en) | 2017-06-21 | 2018-12-27 | Edwards Lifesciences Corporation | Dual-wireform limited expansion heart valves |
US10575948B2 (en) | 2017-08-03 | 2020-03-03 | Cardiovalve Ltd. | Prosthetic heart valve |
US11246704B2 (en) | 2017-08-03 | 2022-02-15 | Cardiovalve Ltd. | Prosthetic heart valve |
US10888421B2 (en) | 2017-09-19 | 2021-01-12 | Cardiovalve Ltd. | Prosthetic heart valve with pouch |
US10537426B2 (en) | 2017-08-03 | 2020-01-21 | Cardiovalve Ltd. | Prosthetic heart valve |
US11793633B2 (en) | 2017-08-03 | 2023-10-24 | Cardiovalve Ltd. | Prosthetic heart valve |
US11395726B2 (en) | 2017-09-11 | 2022-07-26 | Incubar Llc | Conduit vascular implant sealing device for reducing endoleaks |
WO2019118371A1 (en) | 2017-12-11 | 2019-06-20 | California Institute Of Technology | Systems, devices, and methods relating to the manufacture of intravascularly implantable prosthetic valves |
GB201720803D0 (en) | 2017-12-13 | 2018-01-24 | Mitraltech Ltd | Prosthetic Valve and delivery tool therefor |
GB201800399D0 (en) | 2018-01-10 | 2018-02-21 | Mitraltech Ltd | Temperature-control during crimping of an implant |
US11337805B2 (en) | 2018-01-23 | 2022-05-24 | Edwards Lifesciences Corporation | Prosthetic valve holders, systems, and methods |
USD908874S1 (en) | 2018-07-11 | 2021-01-26 | Edwards Lifesciences Corporation | Collapsible heart valve sizer |
US11517428B2 (en) | 2018-11-01 | 2022-12-06 | Edwards Lifesciences Corporation | Transcatheter pulmonic regenerative valve |
EP4076284A1 (en) | 2019-12-16 | 2022-10-26 | Edwards Lifesciences Corporation | Valve holder assembly with suture looping protection |
JP2023515342A (en) * | 2020-02-18 | 2023-04-13 | エルエスアイ ソルーションズ インコーポレーテッド | Cardiac repair structures and devices and methods therefore |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0179562A1 (en) * | 1984-09-28 | 1986-04-30 | The University of Glasgow, University Court | A heart valve prosthesis |
US5161955A (en) | 1991-08-20 | 1992-11-10 | Danielson Associates, Inc. | High vacuum pump using bulk getter material |
WO1994004099A1 (en) * | 1992-08-13 | 1994-03-03 | Autogenics | Tissue heart valve with concentric mating stents |
US5326371A (en) | 1991-01-24 | 1994-07-05 | Autogenics | Rapid assembly, concentric mating stent, tissue heart valve with enhanced clamping and tissue alignment |
US5425741A (en) | 1993-12-17 | 1995-06-20 | Autogenics | Tissue cutting die |
Family Cites Families (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2822819A (en) | 1953-08-07 | 1958-02-11 | Geeraert Corp | Cuspate check valve |
US3548418A (en) | 1968-05-03 | 1970-12-22 | Cutter Lab | Graft valve transplantation for human hearts and graft-support ring therefor |
US3570014A (en) | 1968-09-16 | 1971-03-16 | Warren D Hancock | Stent for heart valve |
US3714671A (en) | 1970-11-30 | 1973-02-06 | Cutter Lab | Tissue-type heart valve with a graft support ring or stent |
US3755823A (en) | 1971-04-23 | 1973-09-04 | Hancock Laboratories Inc | Flexible stent for heart valve |
US3744062A (en) | 1971-10-08 | 1973-07-10 | V Parsonnet | Heart valve construction having a collagen cover encapsulation thereon |
US4291420A (en) | 1973-11-09 | 1981-09-29 | Medac Gesellschaft Fur Klinische Spezialpraparate Mbh | Artificial heart valve |
US3983581A (en) | 1975-01-20 | 1976-10-05 | William W. Angell | Heart valve stent |
US4192020A (en) | 1975-05-07 | 1980-03-11 | Washington University | Heart valve prosthesis |
US4035849A (en) | 1975-11-17 | 1977-07-19 | William W. Angell | Heart valve stent and process for preparing a stented heart valve prosthesis |
AR206762A1 (en) | 1976-01-01 | 1976-08-13 | Pisanu A | LOW PROFILE BIOPROTHESIS DERIVED FROM PORCINE HETEROLOGICAL AORTIC VALVE |
CA1069652A (en) | 1976-01-09 | 1980-01-15 | Alain F. Carpentier | Supported bioprosthetic heart valve with compliant orifice ring |
US4084268A (en) | 1976-04-22 | 1978-04-18 | Shiley Laboratories, Incorporated | Prosthetic tissue heart valve |
US4297749A (en) | 1977-04-25 | 1981-11-03 | Albany International Corp. | Heart valve prosthesis |
US4172295A (en) | 1978-01-27 | 1979-10-30 | Shiley Scientific, Inc. | Tri-cuspid three-tissue prosthetic heart valve |
US4247292A (en) | 1979-06-06 | 1981-01-27 | Angell William W | Natural tissue heart valve fixation process |
EP0125393B1 (en) * | 1980-11-03 | 1987-12-09 | Shiley Incorporated | Prosthetic heart valve |
US4388735A (en) | 1980-11-03 | 1983-06-21 | Shiley Inc. | Low profile prosthetic xenograft heart valve |
US4470157A (en) | 1981-04-27 | 1984-09-11 | Love Jack W | Tricuspid prosthetic tissue heart valve |
US4501030A (en) | 1981-08-17 | 1985-02-26 | American Hospital Supply Corporation | Method of leaflet attachment for prosthetic heart valves |
DE3365190D1 (en) | 1982-01-20 | 1986-09-18 | Martin Morris Black | Artificial heart valves |
US4458570A (en) * | 1982-01-25 | 1984-07-10 | Marvin Glass & Associates | Sheet material dispenser |
GB8300636D0 (en) | 1983-01-11 | 1983-02-09 | Black M M | Heart valve replacements |
CH672247A5 (en) | 1986-03-06 | 1989-11-15 | Mo Vysshee Tekhnicheskoe Uchil | |
US4725274A (en) | 1986-10-24 | 1988-02-16 | Baxter Travenol Laboratories, Inc. | Prosthetic heart valve |
US4851000A (en) | 1987-07-31 | 1989-07-25 | Pacific Biomedical Holdings, Ltd. | Bioprosthetic valve stent |
US5037434A (en) | 1990-04-11 | 1991-08-06 | Carbomedics, Inc. | Bioprosthetic heart valve with elastic commissures |
US5147391A (en) | 1990-04-11 | 1992-09-15 | Carbomedics, Inc. | Bioprosthetic heart valve with semi-permeable commissure posts and deformable leaflets |
US5489298A (en) | 1991-01-24 | 1996-02-06 | Autogenics | Rapid assembly concentric mating stent, tissue heart valve with enhanced clamping and tissue exposure |
US5755782A (en) | 1991-01-24 | 1998-05-26 | Autogenics | Stents for autologous tissue heart valve |
GB9312666D0 (en) * | 1993-06-18 | 1993-08-04 | Vesely Ivan | Bioprostetic heart valve |
US5554673A (en) * | 1993-11-29 | 1996-09-10 | Polygenex International, Inc. | Dip molded polyurethane film compositions |
US5595571A (en) * | 1994-04-18 | 1997-01-21 | Hancock Jaffe Laboratories | Biological material pre-fixation treatment |
US5855601A (en) * | 1996-06-21 | 1999-01-05 | The Trustees Of Columbia University In The City Of New York | Artificial heart valve and method and device for implanting the same |
EP1014895B1 (en) * | 1996-12-10 | 2006-03-08 | Purdue Research Foundation | Artificial vascular valves |
US5928281A (en) * | 1997-03-27 | 1999-07-27 | Baxter International Inc. | Tissue heart valves |
US5935163A (en) * | 1998-03-31 | 1999-08-10 | Shelhigh, Inc. | Natural tissue heart valve prosthesis |
US6095968A (en) * | 1998-04-10 | 2000-08-01 | Cardio Technologies, Inc. | Reinforcement device |
US6254636B1 (en) * | 1998-06-26 | 2001-07-03 | St. Jude Medical, Inc. | Single suture biological tissue aortic stentless valve |
-
1998
- 1998-09-28 US US09/161,809 patent/US6334873B1/en not_active Expired - Lifetime
-
1999
- 1999-09-22 JP JP2000571856A patent/JP2002525169A/en active Pending
- 1999-09-22 CN CN99811423A patent/CN1328436A/en active Pending
- 1999-09-22 AU AU62594/99A patent/AU6259499A/en not_active Abandoned
- 1999-09-22 WO PCT/US1999/021997 patent/WO2000018333A1/en not_active Application Discontinuation
- 1999-09-22 EP EP99949797A patent/EP1117354A1/en not_active Withdrawn
-
2001
- 2001-10-16 US US09/982,609 patent/US20020026238A1/en not_active Abandoned
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0179562A1 (en) * | 1984-09-28 | 1986-04-30 | The University of Glasgow, University Court | A heart valve prosthesis |
US5326371A (en) | 1991-01-24 | 1994-07-05 | Autogenics | Rapid assembly, concentric mating stent, tissue heart valve with enhanced clamping and tissue alignment |
US5161955A (en) | 1991-08-20 | 1992-11-10 | Danielson Associates, Inc. | High vacuum pump using bulk getter material |
WO1994004099A1 (en) * | 1992-08-13 | 1994-03-03 | Autogenics | Tissue heart valve with concentric mating stents |
US5425741A (en) | 1993-12-17 | 1995-06-20 | Autogenics | Tissue cutting die |
Cited By (382)
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---|---|---|---|---|
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US9486312B2 (en) | 1996-12-31 | 2016-11-08 | Edwards Lifesciences Pvt, Inc. | Method of manufacturing a prosthetic valve |
US9629714B2 (en) | 1996-12-31 | 2017-04-25 | Edwards Lifesciences Pvt, Inc. | Collapsible prosthetic valve |
US9421100B2 (en) | 1999-12-31 | 2016-08-23 | ABPS Venture One, Ltd., a wholly owned subsidiary of Palmaz Scientific, Inc. | Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof |
US8992597B2 (en) | 1999-12-31 | 2015-03-31 | Abps Venture One, Ltd. | Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof |
US8221493B2 (en) | 1999-12-31 | 2012-07-17 | Abps Venture One, Ltd. | Endoluminal cardiac and venous valve prostheses and methods of manufacture and delivery thereof |
WO2001064137A1 (en) * | 2000-02-28 | 2001-09-07 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Anchoring system for implantable heart valve prostheses |
USRE45130E1 (en) | 2000-02-28 | 2014-09-09 | Jenavalve Technology Gmbh | Device for fastening and anchoring cardiac valve prostheses |
US10022220B2 (en) | 2000-04-06 | 2018-07-17 | Edwards Lifesciences Corporation | Methods of implanting minimally-invasive prosthetic heart valves |
US9707074B2 (en) | 2001-03-23 | 2017-07-18 | Edwards Lifesciences Corporation | Method for treating an aortic valve |
US9241788B2 (en) | 2001-03-23 | 2016-01-26 | Edwards Lifesciences Corporation | Method for treating an aortic valve |
US8206438B2 (en) | 2001-03-23 | 2012-06-26 | Edwards Lifesciences Corporation | Prosthetic heart valve having flared outflow section |
JP2004531355A (en) * | 2001-07-03 | 2004-10-14 | アドヴァンスド バイオ プロスセティック サーフェシーズ リミテッド | Valve prosthesis having metal or pseudo-metal structure and method of manufacture |
US8585756B2 (en) | 2001-08-03 | 2013-11-19 | Jenavalve Technology, Inc. | Methods of treating valves |
US8579965B2 (en) | 2001-08-03 | 2013-11-12 | Jenavalve Technology, Inc. | Methods of implanting an implantation device |
US9949824B2 (en) | 2001-08-03 | 2018-04-24 | Jenavalve Technology, Inc. | Devices useful for implantation at a heart valve |
US11007052B2 (en) | 2001-08-03 | 2021-05-18 | Jenavalve Technology, Inc. | Devices useful for implantation at a heart valve |
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US8303653B2 (en) | 2001-08-03 | 2012-11-06 | Philipp Bonhoeffer | Implant implantation unit and procedure for implanting the unit |
US9889002B2 (en) | 2001-08-03 | 2018-02-13 | Jenavalve Technology, Inc. | Devices useful for implantation at a heart valve |
US8216301B2 (en) | 2001-08-03 | 2012-07-10 | Philipp Bonhoeffer | Implant implantation unit |
US9539091B2 (en) | 2001-09-13 | 2017-01-10 | Edwards Lifesciences Corporation | Methods and apparatuses for deploying minimally-invasive heart valves |
US9572664B2 (en) | 2001-09-13 | 2017-02-21 | Edwards Lifesciences Corporation | Methods and apparatuses for deploying minimally-invasive heart valves |
US9452046B2 (en) | 2001-09-13 | 2016-09-27 | Edwards Lifesciences Corporation | Methods and apparatuses for deploying minimally-invasive heart valves |
US9848985B2 (en) | 2001-09-13 | 2017-12-26 | Edwards Lifesciences Corporation | Methods and apparatuses for deploying minimally-invasive heart valves |
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US10052203B2 (en) | 2001-10-11 | 2018-08-21 | Edwards Lifesciences Pvt, Inc. | Prosthetic heart valve and method |
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US11123182B2 (en) | 2001-10-11 | 2021-09-21 | Edwards Lifesciences Pvt, Inc. | Prosthetic heart valve and method |
US9937039B2 (en) | 2001-10-11 | 2018-04-10 | Edwards Lifesciences Pvt, Inc. | Prosthetic heart valve and method |
US9339383B2 (en) | 2001-10-11 | 2016-05-17 | Edwards Lifesciences Pvt, Inc. | Prosthetic heart valve and method |
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US9629717B2 (en) | 2001-10-11 | 2017-04-25 | Edwards Lifesciences Pvt, Inc. | Prosthetic heart valve and method |
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US9241793B2 (en) | 2003-10-02 | 2016-01-26 | Edwards Lifesciences Corporation | Method of implanting a prosthetic aortic valve having non-laminar flow |
US11076955B2 (en) | 2003-10-02 | 2021-08-03 | Edwards Lifesciences Corporation | Implantable prosthetic heart valve |
US11517431B2 (en) | 2005-01-20 | 2022-12-06 | Jenavalve Technology, Inc. | Catheter system for implantation of prosthetic heart valves |
US9028545B2 (en) | 2005-06-13 | 2015-05-12 | Edwards Lifesciences Corporation | Method of delivering a prosthetic heart valve |
US10507097B2 (en) | 2006-07-31 | 2019-12-17 | Edwards Lifesciences Cardiaq Llc | Surgical implant devices and methods for their manufacture and use |
US10925760B2 (en) | 2006-07-31 | 2021-02-23 | Edwards Lifesciences Cardiaq Llc | Sealable endovascular implants and methods for their use |
US10687968B2 (en) | 2006-07-31 | 2020-06-23 | Edwards Lifesciences Cardiaq Llc | Sealable endovascular implants and methods for their use |
US11877941B2 (en) | 2006-07-31 | 2024-01-23 | Edwards Lifesciences Cardiaq Llc | Sealable endovascular implants and methods for their use |
US9114008B2 (en) | 2006-12-22 | 2015-08-25 | Edwards Lifesciences Corporation | Implantable prosthetic valve assembly and method for making the same |
US9192471B2 (en) | 2007-01-08 | 2015-11-24 | Millipede, Inc. | Device for translumenal reshaping of a mitral valve annulus |
US11357624B2 (en) | 2007-04-13 | 2022-06-14 | Jenavalve Technology, Inc. | Medical device for treating a heart valve insufficiency |
US8409274B2 (en) | 2007-04-26 | 2013-04-02 | St. Jude Medical, Inc. | Techniques for attaching flexible leaflets of prosthetic heart valves to supporting structures |
WO2008133852A1 (en) * | 2007-04-26 | 2008-11-06 | St. Jude Medical, Inc. | Techniques for attaching flexible leaflets of prosthetic heart valves to supporting structures |
US9078749B2 (en) | 2007-09-13 | 2015-07-14 | Georg Lutter | Truncated cone heart valve stent |
US9730792B2 (en) | 2007-09-13 | 2017-08-15 | Georg Lutter | Truncated cone heart valve stent |
US9095433B2 (en) | 2007-09-13 | 2015-08-04 | Georg Lutter | Truncated cone heart valve stent |
US11213387B2 (en) | 2007-09-13 | 2022-01-04 | Georg Lutter | Truncated cone heart valve stent |
US10456248B2 (en) | 2007-09-13 | 2019-10-29 | Georg Lutter | Truncated cone heart valve stent |
US9254192B2 (en) | 2007-09-13 | 2016-02-09 | Georg Lutter | Truncated cone heart valve stent |
US11007053B2 (en) | 2007-09-26 | 2021-05-18 | St. Jude Medical, Llc | Collapsible prosthetic heart valves |
US10292813B2 (en) | 2007-09-26 | 2019-05-21 | St. Jude Medical, Llc | Collapsible prosthetic heart valves |
US9693859B2 (en) | 2007-09-26 | 2017-07-04 | St. Jude Medical, Llc | Collapsible prosthetic heart valves |
US11903823B2 (en) | 2007-09-26 | 2024-02-20 | St. Jude Medical, Llc | Collapsible prosthetic heart valves |
US9636221B2 (en) | 2007-09-26 | 2017-05-02 | St. Jude Medical, Inc. | Collapsible prosthetic heart valves |
US10426604B2 (en) | 2007-09-28 | 2019-10-01 | St. Jude Medical, Llc | Collapsible-expandable prosthetic heart valves with structures for clamping native tissue |
US11382740B2 (en) | 2007-09-28 | 2022-07-12 | St. Jude Medical, Llc | Collapsible-expandable prosthetic heart valves with structures for clamping native tissue |
US11534294B2 (en) | 2007-09-28 | 2022-12-27 | St. Jude Medical, Llc | Collapsible-expandable prosthetic heart valves with structures for clamping native tissue |
US9820851B2 (en) | 2007-09-28 | 2017-11-21 | St. Jude Medical, Llc | Collapsible-expandable prosthetic heart valves with structures for clamping native tissue |
US11660187B2 (en) | 2007-09-28 | 2023-05-30 | St. Jude Medical, Llc | Collapsible-expandable prosthetic heart valves with structures for clamping native tissue |
US10413406B2 (en) | 2007-12-14 | 2019-09-17 | Edwards Lifesciences Corporation | Leaflet attachment frame for a prosthetic valve |
US10413404B2 (en) | 2007-12-14 | 2019-09-17 | Edwards Lifesciences Corporation | Leaflet attachment frame for a prosthetic valve |
US10413405B2 (en) | 2007-12-14 | 2019-09-17 | Edwards Lifesciences Corporation | Leaflet attachment frame for a prosthetic valve |
US11154398B2 (en) | 2008-02-26 | 2021-10-26 | JenaValve Technology. Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US11564794B2 (en) | 2008-02-26 | 2023-01-31 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US10993805B2 (en) | 2008-02-26 | 2021-05-04 | Jenavalve Technology, Inc. | Stent for the positioning and anchoring of a valvular prosthesis in an implantation site in the heart of a patient |
US10076412B2 (en) | 2008-02-29 | 2018-09-18 | Edwards Lifesciences Corporation | Expandable member for deploying a prosthetic device |
US11103346B2 (en) | 2008-02-29 | 2021-08-31 | Edwards Lifesciences Corporation | Expandable member for deploying a prosthetic device |
US9241792B2 (en) | 2008-02-29 | 2016-01-26 | Edwards Lifesciences Corporation | Two-step heart valve implantation |
US10952846B2 (en) | 2008-05-01 | 2021-03-23 | Edwards Lifesciences Corporation | Method of replacing mitral valve |
US10617520B2 (en) | 2008-05-01 | 2020-04-14 | Edwards Lifesciences Corporation | Method of replacing mitral valve |
US11717401B2 (en) | 2008-05-01 | 2023-08-08 | Edwards Lifesciences Corporation | Prosthetic heart valve assembly |
US10426611B2 (en) | 2008-06-06 | 2019-10-01 | Edwards Lifesciences Corporation | Low profile transcatheter heart valve |
US11744701B2 (en) | 2008-06-06 | 2023-09-05 | Edwards Lifesciences Corporation | Low profile transcatheter heart valve |
US10413407B2 (en) | 2008-06-06 | 2019-09-17 | Edwards Lifesciences Corporation | Low profile transcatheter heart valve |
WO2009149462A3 (en) * | 2008-06-06 | 2010-02-04 | Edwards Lifesciences Corporation | Low profile transcatheter heart valve |
US10492905B2 (en) | 2008-06-06 | 2019-12-03 | Edwards Lifesciences Corporation | Low profile transcatheter heart valve |
US11648111B2 (en) | 2008-06-06 | 2023-05-16 | Edwards Lifesciences Corporation | Low profile transcatheter heart valve |
US11213388B2 (en) | 2008-06-06 | 2022-01-04 | Edwards Lifesciences Corporation | Low profile transcatheter heart valve |
US10292817B2 (en) | 2008-06-06 | 2019-05-21 | Edwards Lifesciences Corporation | Low profile transcatheter heart valve |
US11696826B2 (en) | 2008-06-06 | 2023-07-11 | Edwards Lifesciences Corporation | Low profile transcatheter heart valve |
US9662204B2 (en) | 2008-06-06 | 2017-05-30 | Edwards Lifesciences Corporation | Low profile transcatheter heart valve |
US9561101B2 (en) | 2008-06-20 | 2017-02-07 | Edwards Lifesciences Corporation | Two-part prosthetic valve system |
US9675449B2 (en) | 2008-07-15 | 2017-06-13 | St. Jude Medical, Llc | Collapsible and re-expandable prosthetic heart valve cuff designs and complementary technological applications |
US11504228B2 (en) | 2008-07-15 | 2022-11-22 | St. Jude Medical, Llc | Collapsible and re-expandable prosthetic heart valve cuff designs and complementary technological applications |
US9681949B2 (en) | 2008-07-15 | 2017-06-20 | St. Jude Medical, Llc | Collapsible and re-expandable prosthetic heart valve cuff designs and complementary technological applications |
US10010410B2 (en) | 2008-07-15 | 2018-07-03 | St. Jude Medical, Llc | Collapsible and re-expandable prosthetic heart valve cuff designs and complementary technological applications |
US10314694B2 (en) | 2008-07-15 | 2019-06-11 | St. Jude Medical, Llc | Collapsible and re-expandable prosthetic heart valve cuff designs and complementary technological applications |
US11141270B2 (en) | 2008-08-22 | 2021-10-12 | Edwards Lifesciences Corporation | Prosthetic heart valve and delivery apparatus |
US10238487B2 (en) | 2008-08-22 | 2019-03-26 | Edwards Lifesciences Corporation | Prosthetic heart valve and delivery apparatus |
US10952848B2 (en) | 2008-08-22 | 2021-03-23 | Edwards Lifesciences Corporation | Methods of loading a prosthetic valve in a delivery apparatus |
US11109970B2 (en) | 2008-08-22 | 2021-09-07 | Edwards Lifesciences Corporation | Prosthetic heart valve and delivery apparatus |
US11540918B2 (en) | 2008-08-22 | 2023-01-03 | Edwards Lifesciences Corporation | Prosthetic heart valve and delivery apparatus |
US10945839B2 (en) | 2008-08-22 | 2021-03-16 | Edwards Lifesciences Corporation | Prosthetic heart valve and delivery apparatus |
US9364325B2 (en) | 2008-08-22 | 2016-06-14 | Edwards Lifesciences Corporation | Prosthetic heart valve delivery system and method |
US11116631B2 (en) | 2008-08-22 | 2021-09-14 | Edwards Lifesciences Corporation | Prosthetic heart valve delivery methods |
US10932906B2 (en) | 2008-08-22 | 2021-03-02 | Edwards Lifesciences Corporation | Prosthetic heart valve and delivery apparatus |
US11730597B2 (en) | 2008-08-22 | 2023-08-22 | Edwards Lifesciences Corporation | Prosthetic heart valve and delivery apparatus |
US11116632B2 (en) | 2008-08-22 | 2021-09-14 | Edwards Lifesciences Corporation | Transvascular delivery systems |
US10820994B2 (en) | 2008-08-22 | 2020-11-03 | Edwards Lifesciences Corporation | Methods for delivering a prosthetic valve |
US11690718B2 (en) | 2008-08-22 | 2023-07-04 | Edwards Lifesciences Corporation | Prosthetic heart valve and delivery apparatus |
US9301840B2 (en) | 2008-10-10 | 2016-04-05 | Edwards Lifesciences Corporation | Expandable introducer sheath |
US10568732B2 (en) | 2009-07-02 | 2020-02-25 | Edwards Lifesciences Cardiaq Llc | Surgical implant devices and methods for their manufacture and use |
US11766323B2 (en) | 2009-07-02 | 2023-09-26 | Edwards Lifesciences Cardiaq Llc | Surgical implant devices and methods for their manufacture and use |
US8986373B2 (en) | 2009-12-04 | 2015-03-24 | Edwards Lifesciences Corporation | Method for implanting a prosthetic mitral valve |
US9084676B2 (en) | 2009-12-04 | 2015-07-21 | Edwards Lifesciences Corporation | Apparatus for treating a mitral valve |
US9717591B2 (en) | 2009-12-04 | 2017-08-01 | Edwards Lifesciences Corporation | Prosthetic valve for replacing mitral valve |
US9433500B2 (en) | 2009-12-04 | 2016-09-06 | Edwards Lifesciences Corporation | Prosthetic valve for replacing mitral valve |
US8926691B2 (en) | 2009-12-04 | 2015-01-06 | Edwards Lifesciences Corporation | Apparatus for treating a mitral valve |
US11179236B2 (en) | 2009-12-08 | 2021-11-23 | Colorado State University Research Foundation | Device and system for transcatheter mitral valve replacement |
US11730589B2 (en) | 2010-03-05 | 2023-08-22 | Edwards Lifesciences Corporation | Prosthetic heart valve having an inner frame and an outer frame |
US11589981B2 (en) | 2010-05-25 | 2023-02-28 | Jenavalve Technology, Inc. | Prosthetic heart valve and transcatheter delivered endoprosthesis comprising a prosthetic heart valve and a stent |
US11446140B2 (en) | 2010-07-09 | 2022-09-20 | Highlife Sas | Transcatheter atrio-ventricular valve prosthesis |
US11259921B2 (en) | 2010-07-09 | 2022-03-01 | Highlife Sas | Transcatheter atrio-ventricular valve prosthesis |
US11259922B2 (en) | 2010-07-09 | 2022-03-01 | Highlife Sas | Transcatheter atrio-ventricular valve prosthesis |
US9375312B2 (en) | 2010-07-09 | 2016-06-28 | Highlife Sas | Transcatheter atrio-ventricular valve prosthesis |
US11311377B2 (en) | 2010-07-09 | 2022-04-26 | Highlife Sas | Transcatheter atrio-ventricular valve prosthesis |
US11883283B2 (en) | 2010-07-09 | 2024-01-30 | Highlife Sas | Transcatheter atrio-ventricular valve prosthesis |
US9931206B2 (en) | 2010-07-09 | 2018-04-03 | Highlife Sas | Transcatheter atrio-ventricular valve prosthesis |
US9326853B2 (en) | 2010-07-23 | 2016-05-03 | Edwards Lifesciences Corporation | Retaining mechanisms for prosthetic valves |
US9795480B2 (en) | 2010-08-24 | 2017-10-24 | Millipede, Inc. | Reconfiguring tissue features of a heart annulus |
US10729543B2 (en) | 2010-10-05 | 2020-08-04 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US11793632B2 (en) | 2010-10-05 | 2023-10-24 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US10828155B2 (en) | 2010-10-05 | 2020-11-10 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US8568475B2 (en) | 2010-10-05 | 2013-10-29 | Edwards Lifesciences Corporation | Spiraled commissure attachment for prosthetic valve |
US10842622B2 (en) | 2010-10-05 | 2020-11-24 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US10537423B2 (en) | 2010-10-05 | 2020-01-21 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US10478292B2 (en) | 2010-10-05 | 2019-11-19 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US11628062B2 (en) | 2010-10-05 | 2023-04-18 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US11759320B2 (en) | 2010-10-05 | 2023-09-19 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US10849743B2 (en) | 2010-10-05 | 2020-12-01 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US9393110B2 (en) | 2010-10-05 | 2016-07-19 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US11123184B2 (en) | 2010-10-05 | 2021-09-21 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US10433959B2 (en) | 2010-10-05 | 2019-10-08 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US10433958B2 (en) | 2010-10-05 | 2019-10-08 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US10849741B2 (en) | 2010-10-05 | 2020-12-01 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US10849742B2 (en) | 2010-10-05 | 2020-12-01 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US10856976B2 (en) | 2010-10-05 | 2020-12-08 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US11540911B2 (en) | 2010-12-29 | 2023-01-03 | Edwards Lifesciences Cardiaq Llc | Surgical implant devices and methods for their manufacture and use |
US11801132B2 (en) | 2011-02-25 | 2023-10-31 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US10561494B2 (en) | 2011-02-25 | 2020-02-18 | Edwards Lifesciences Corporation | Prosthetic heart valve delivery apparatus |
US11129713B2 (en) | 2011-02-25 | 2021-09-28 | Edwards Lifesciences Corporation | Prosthetic heart valve delivery apparatus |
US11737868B2 (en) | 2011-02-25 | 2023-08-29 | Edwards Lifesciences Corporation | Prosthetic heart valve delivery apparatus |
US11399934B2 (en) | 2011-02-25 | 2022-08-02 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US9155619B2 (en) | 2011-02-25 | 2015-10-13 | Edwards Lifesciences Corporation | Prosthetic heart valve delivery apparatus |
US11737871B2 (en) | 2011-02-25 | 2023-08-29 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US9289282B2 (en) | 2011-05-31 | 2016-03-22 | Edwards Lifesciences Corporation | System and method for treating valve insufficiency or vessel dilatation |
US9999506B2 (en) | 2011-05-31 | 2018-06-19 | Edwards Lifesciences Corporation | System and method for treating valve insufficiency or vessel dilatation |
EP2726024A4 (en) * | 2011-06-30 | 2015-03-11 | Edwards Lifesciences Corp | Systems, dies, and methods for processing pericardial tissue |
EP2726024A1 (en) * | 2011-06-30 | 2014-05-07 | Edwards Lifesciences Corporation | Systems, dies, and methods for processing pericardial tissue |
US8795357B2 (en) | 2011-07-15 | 2014-08-05 | Edwards Lifesciences Corporation | Perivalvular sealing for transcatheter heart valve |
US9339384B2 (en) | 2011-07-27 | 2016-05-17 | Edwards Lifesciences Corporation | Delivery systems for prosthetic heart valve |
US11877929B2 (en) | 2011-07-27 | 2024-01-23 | Edwards Lifesciences Corporation | Delivery systems for prosthetic heart valve |
US11554013B2 (en) | 2011-07-27 | 2023-01-17 | Edwards Lifesciences Corporation | Delivery systems for prosthetic heart valve |
US11291542B2 (en) | 2011-07-27 | 2022-04-05 | Edwards Lifesciences Corporation | Delivery systems for prosthetic heart valve |
US10856977B2 (en) | 2011-07-27 | 2020-12-08 | Edwards Lifesciences Corporation | Delivery systems for prosthetic heart valve |
US10179047B2 (en) | 2011-07-27 | 2019-01-15 | Edwards Lifesciences Corporation | Delivery systems for prosthetic heart valve |
US11864997B2 (en) | 2011-07-27 | 2024-01-09 | Edwards Lifesciences Corporation | Delivery systems for prosthetic heart valve |
US9119716B2 (en) | 2011-07-27 | 2015-09-01 | Edwards Lifesciences Corporation | Delivery systems for prosthetic heart valve |
US10617519B2 (en) | 2011-08-11 | 2020-04-14 | Tendyne Holdings, Inc. | Prosthetic valves and related inventions |
US11311374B2 (en) | 2011-08-11 | 2022-04-26 | Tendyne Holdings, Inc. | Prosthetic valves and related inventions |
US9480559B2 (en) | 2011-08-11 | 2016-11-01 | Tendyne Holdings, Inc. | Prosthetic valves and related inventions |
US11135055B2 (en) | 2011-08-11 | 2021-10-05 | Tendyne Holdings, Inc. | Prosthetic valves and related inventions |
US11484404B2 (en) | 2011-08-11 | 2022-11-01 | Tendyne Holdings, Inc. | Prosthetic valves and related inventions |
US11123181B2 (en) | 2011-08-11 | 2021-09-21 | Tendyne Holdings, Inc. | Prosthetic valves and related inventions |
US10639145B2 (en) | 2011-08-11 | 2020-05-05 | Tendyne Holdings, Inc. | Prosthetic valves and related inventions |
US11123180B2 (en) | 2011-08-11 | 2021-09-21 | Tendyne Holdings, Inc. | Prosthetic valves and related inventions |
US11382737B2 (en) | 2011-08-11 | 2022-07-12 | Tendyne Holdings, Inc. | Prosthetic valves and related inventions |
US11364116B2 (en) | 2011-08-11 | 2022-06-21 | Tendyne Holdings, Inc. | Prosthetic valves and related inventions |
US9833315B2 (en) | 2011-08-11 | 2017-12-05 | Tendyne Holdings, Inc. | Prosthetic valves and related inventions |
US10874508B2 (en) | 2011-10-21 | 2020-12-29 | Edwards Lifesciences Cardiaq Llc | Actively controllable stent, stent graft, heart valve and method of controlling same |
US11707356B2 (en) | 2011-10-21 | 2023-07-25 | Edwards Lifesciences Cardiaq Llc | Actively controllable stent, stent graft, heart valve and method of controlling same |
US9510947B2 (en) | 2011-10-21 | 2016-12-06 | Jenavalve Technology, Inc. | Catheter system for introducing an expandable heart valve stent into the body of a patient |
US10478295B2 (en) | 2011-10-21 | 2019-11-19 | Edwards Lifesciences Cardiaq Llc | Actively controllable stent, stent graft, heart valve and method of controlling same |
US10238514B2 (en) | 2011-10-21 | 2019-03-26 | Edwards Lifesciences Cardiaq Llc | Actively controllable stent, stent graft, heart valve and method of controlling same |
US10980650B2 (en) | 2011-10-21 | 2021-04-20 | Edwards Lifesciences Cardiaq Llc | Actively controllable stent, stent graft, heart valve and method of controlling same |
US11129710B2 (en) | 2011-12-09 | 2021-09-28 | Edwards Lifesciences Corporation | Prosthetic heart valve having improved commissure supports |
US9168131B2 (en) | 2011-12-09 | 2015-10-27 | Edwards Lifesciences Corporation | Prosthetic heart valve having improved commissure supports |
US11690710B2 (en) | 2011-12-09 | 2023-07-04 | Edwards Lifesciences Corporation | Prosthetic heart valve having improved commissure supports |
US11666434B2 (en) | 2011-12-09 | 2023-06-06 | Edwards Lifesciences Corporation | Prosthetic heart valve having improved commissure supports |
US9757229B2 (en) | 2011-12-09 | 2017-09-12 | Edwards Lifesciences Corporation | Prosthetic heart valve having improved commissure supports |
US10363132B2 (en) | 2011-12-09 | 2019-07-30 | Edwards Lifesciences Corporation | Prosthetic heart valve having improved commissure supports |
US11207175B2 (en) | 2011-12-09 | 2021-12-28 | Edwards Lifesciences Corporation | Prosthetic heart valve having improved commissure supports |
US9827092B2 (en) | 2011-12-16 | 2017-11-28 | Tendyne Holdings, Inc. | Tethers for prosthetic mitral valve |
US10952844B2 (en) | 2011-12-16 | 2021-03-23 | Tendyne Holdings, Inc. | Tethers for prosthetic mitral valve |
US9878127B2 (en) | 2012-05-16 | 2018-01-30 | Jenavalve Technology, Inc. | Catheter delivery system for heart valve prosthesis |
US11166809B2 (en) | 2012-07-25 | 2021-11-09 | W. L. Gore & Associates, Inc. | Everting transcatheter valve and methods |
US11759318B2 (en) | 2012-07-28 | 2023-09-19 | Tendyne Holdings, Inc. | Multi-component designs for heart valve retrieval device, sealing structures and stent assembly |
US9895221B2 (en) | 2012-07-28 | 2018-02-20 | Tendyne Holdings, Inc. | Multi-component designs for heart valve retrieval device, sealing structures and stent assembly |
US9675454B2 (en) | 2012-07-30 | 2017-06-13 | Tendyne Holdings, Inc. | Delivery systems and methods for transcatheter prosthetic valves |
US10219900B2 (en) | 2012-07-30 | 2019-03-05 | Tendyne Holdings, Inc. | Delivery systems and methods for transcatheter prosthetic valves |
US11090155B2 (en) | 2012-07-30 | 2021-08-17 | Tendyne Holdings, Inc. | Delivery systems and methods for transcatheter prosthetic valves |
US9907652B2 (en) | 2012-09-06 | 2018-03-06 | Edwards Lifesciences Corporation | Heart valve sealing devices |
US9510946B2 (en) | 2012-09-06 | 2016-12-06 | Edwards Lifesciences Corporation | Heart valve sealing devices |
US9414918B2 (en) | 2012-09-06 | 2016-08-16 | Edwards Lifesciences Corporation | Heart valve sealing devices |
US10849755B2 (en) | 2012-09-14 | 2020-12-01 | Boston Scientific Scimed, Inc. | Mitral valve inversion prostheses |
US10543088B2 (en) | 2012-09-14 | 2020-01-28 | Boston Scientific Scimed, Inc. | Mitral valve inversion prostheses |
US10016276B2 (en) | 2012-11-21 | 2018-07-10 | Edwards Lifesciences Corporation | Retaining mechanisms for prosthetic heart valves |
US11234819B2 (en) | 2012-11-21 | 2022-02-01 | Edwards Lifesciences Corporation | Retaining mechanisms for prosthetic heart valves |
US10660745B2 (en) | 2012-12-19 | 2020-05-26 | W. L. Gore & Associates, Inc. | Methods for improved prosthetic heart valve with leaflet shelving |
US10639144B2 (en) | 2012-12-19 | 2020-05-05 | W. L. Gore & Associates, Inc. | Vertical coaptation zone in a planar portion of prosthetic heart valve leaflet |
US11826248B2 (en) | 2012-12-19 | 2023-11-28 | Edwards Lifesciences Corporation | Vertical coaptation zone in a planar portion of prosthetic heart valve leaflet |
US10881507B2 (en) | 2012-12-19 | 2021-01-05 | W. L. Gore & Associates, Inc. | Prosthetic valves, frames and leaflets and methods thereof |
US11896481B2 (en) | 2012-12-19 | 2024-02-13 | Edwards Lifesciences Corporation | Truncated leaflet for prosthetic heart valves |
US11039917B2 (en) | 2012-12-19 | 2021-06-22 | W. L. Gore & Associates, Inc. | Geometric prosthetic heart valves |
US11872122B2 (en) | 2012-12-19 | 2024-01-16 | Edwards Lifesciences Corporation | Methods for improved prosthetic heart valve with leaflet shelving |
US10463478B2 (en) | 2012-12-19 | 2019-11-05 | W. L. Gore & Associates, Inc. | Truncated leaflet for prosthetic heart valves |
US10966820B2 (en) | 2012-12-19 | 2021-04-06 | W. L. Gore & Associates, Inc. | Geometric control of bending character in prosthetic heart valve leaflets |
US10463481B2 (en) | 2013-02-04 | 2019-11-05 | Edwards Lifesciences Corporation | Prosthetic valve for replacing mitral valve |
US9439763B2 (en) | 2013-02-04 | 2016-09-13 | Edwards Lifesciences Corporation | Prosthetic valve for replacing mitral valve |
US10799347B1 (en) | 2013-02-04 | 2020-10-13 | Edwards Lifesciences Corporation | Prosthetic heart valve with atrial sealing member |
US9168129B2 (en) | 2013-02-12 | 2015-10-27 | Edwards Lifesciences Corporation | Artificial heart valve with scalloped frame design |
US9675452B2 (en) | 2013-02-12 | 2017-06-13 | Edwards Lifesciences Corporation | Artificial heart valve with scalloped frame design |
US11311379B2 (en) | 2013-04-02 | 2022-04-26 | Tendyne Holdings, Inc. | Prosthetic heart valve and systems and methods for delivering the same |
US10463494B2 (en) | 2013-04-02 | 2019-11-05 | Tendyne Holdings, Inc. | Prosthetic heart valve and systems and methods for delivering the same |
US9486306B2 (en) | 2013-04-02 | 2016-11-08 | Tendyne Holdings, Inc. | Inflatable annular sealing device for prosthetic mitral valve |
US10463489B2 (en) | 2013-04-02 | 2019-11-05 | Tendyne Holdings, Inc. | Prosthetic heart valve and systems and methods for delivering the same |
US11224510B2 (en) | 2013-04-02 | 2022-01-18 | Tendyne Holdings, Inc. | Prosthetic heart valve and systems and methods for delivering the same |
US10478293B2 (en) | 2013-04-04 | 2019-11-19 | Tendyne Holdings, Inc. | Retrieval and repositioning system for prosthetic heart valve |
US11364119B2 (en) | 2013-04-04 | 2022-06-21 | Tendyne Holdings, Inc. | Retrieval and repositioning system for prosthetic heart valve |
US9867700B2 (en) | 2013-05-20 | 2018-01-16 | Edwards Lifesciences Corporation | Prosthetic heart valve delivery apparatus |
US9610159B2 (en) | 2013-05-30 | 2017-04-04 | Tendyne Holdings, Inc. | Structural members for prosthetic mitral valves |
US11617645B2 (en) | 2013-05-30 | 2023-04-04 | Tendyne Holdings, Inc. | Structural members for prosthetic mitral valves |
US10405976B2 (en) | 2013-05-30 | 2019-09-10 | Tendyne Holdings, Inc. | Structural members for prosthetic mitral valves |
US10595996B2 (en) | 2013-06-25 | 2020-03-24 | Tendyne Holdings, Inc. | Thrombus management and structural compliance features for prosthetic heart valves |
US9597181B2 (en) | 2013-06-25 | 2017-03-21 | Tendyne Holdings, Inc. | Thrombus management and structural compliance features for prosthetic heart valves |
US11471281B2 (en) | 2013-06-25 | 2022-10-18 | Tendyne Holdings, Inc. | Thrombus management and structural compliance features for prosthetic heart valves |
US10610354B2 (en) | 2013-08-01 | 2020-04-07 | Tendyne Holdings, Inc. | Epicardial anchor devices and methods |
US11612480B2 (en) | 2013-08-01 | 2023-03-28 | Tendyne Holdings, Inc. | Epicardial anchor devices and methods |
US11185405B2 (en) | 2013-08-30 | 2021-11-30 | Jenavalve Technology, Inc. | Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame |
US9867694B2 (en) | 2013-08-30 | 2018-01-16 | Jenavalve Technology Inc. | Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame |
US10433954B2 (en) | 2013-08-30 | 2019-10-08 | Jenavalve Technology, Inc. | Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame |
US11246562B2 (en) | 2013-10-17 | 2022-02-15 | Tendyne Holdings, Inc. | Apparatus and methods for alignment and deployment of intracardiac devices |
US10555718B2 (en) | 2013-10-17 | 2020-02-11 | Tendyne Holdings, Inc. | Apparatus and methods for alignment and deployment of intracardiac devices |
US9526611B2 (en) | 2013-10-29 | 2016-12-27 | Tendyne Holdings, Inc. | Apparatus and methods for delivery of transcatheter prosthetic valves |
US10363135B2 (en) | 2013-10-29 | 2019-07-30 | Tendyne Holdings, Inc. | Apparatus and methods for delivery of transcatheter prosthetic valves |
US11096783B2 (en) | 2013-10-29 | 2021-08-24 | Tendyne Holdings, Inc. | Apparatus and methods for delivery of transcatheter prosthetic valves |
US10849740B2 (en) | 2013-11-06 | 2020-12-01 | St. Jude Medical, Cardiology Division, Inc. | Paravalvular leak sealing mechanism |
US11446143B2 (en) | 2013-11-06 | 2022-09-20 | St. Jude Medical, Cardiology Division, Inc. | Paravalvular leak sealing mechanism |
US9913715B2 (en) | 2013-11-06 | 2018-03-13 | St. Jude Medical, Cardiology Division, Inc. | Paravalvular leak sealing mechanism |
US11395751B2 (en) | 2013-11-11 | 2022-07-26 | Edwards Lifesciences Cardiaq Llc | Systems and methods for manufacturing a stent frame |
US9622863B2 (en) | 2013-11-22 | 2017-04-18 | Edwards Lifesciences Corporation | Aortic insufficiency repair device and method |
US11589988B2 (en) | 2013-11-22 | 2023-02-28 | Edwards Lifesciences Corporation | Valvular insufficiency repair device and method |
US11337810B2 (en) | 2013-11-22 | 2022-05-24 | Edwards Lifesciences Corporation | Valvular insufficiency repair device and method |
US10507106B2 (en) | 2013-11-22 | 2019-12-17 | Edwards Lifesciences Corporation | Aortic insufficiency repair device and method |
US10595993B2 (en) | 2013-12-05 | 2020-03-24 | Edwards Lifesciences Corporation | Method of making an introducer sheath with an inner liner |
US10098734B2 (en) | 2013-12-05 | 2018-10-16 | Edwards Lifesciences Corporation | Prosthetic heart valve and delivery apparatus |
US10368984B2 (en) | 2013-12-06 | 2019-08-06 | W. L. Gore & Associates, Inc. | Asymmetric opening and closing prosthetic valve leaflet |
US10201419B2 (en) | 2014-02-05 | 2019-02-12 | Tendyne Holdings, Inc. | Apparatus and methods for transfemoral delivery of prosthetic mitral valve |
US11589985B2 (en) | 2014-02-05 | 2023-02-28 | Tendyne Holdings, Inc. | Apparatus and methods for transfemoral delivery of prosthetic mitral valve |
US11464628B2 (en) | 2014-02-05 | 2022-10-11 | Tendyne Holdings, Inc. | Expandable epicardial pads and devices and methods for delivery of same |
US11045183B2 (en) | 2014-02-11 | 2021-06-29 | Tendyne Holdings, Inc. | Adjustable tether and epicardial pad system for prosthetic heart valve |
US9986993B2 (en) | 2014-02-11 | 2018-06-05 | Tendyne Holdings, Inc. | Adjustable tether and epicardial pad system for prosthetic heart valve |
US10517728B2 (en) | 2014-03-10 | 2019-12-31 | Tendyne Holdings, Inc. | Devices and methods for positioning and monitoring tether load for prosthetic mitral valve |
US11382753B2 (en) | 2014-03-10 | 2022-07-12 | Tendyne Holdings, Inc. | Devices and methods for positioning and monitoring tether load for prosthetic mitral valve |
US9532870B2 (en) | 2014-06-06 | 2017-01-03 | Edwards Lifesciences Corporation | Prosthetic valve for replacing a mitral valve |
US9622862B2 (en) | 2014-07-17 | 2017-04-18 | Millipede, Inc. | Prosthetic mitral valve with adjustable support |
US9913706B2 (en) | 2014-07-17 | 2018-03-13 | Millipede, Inc. | Adjustable endolumenal implant for reshaping the mitral valve annulus |
US10136985B2 (en) | 2014-07-17 | 2018-11-27 | Millipede, Inc. | Method of reconfiguring a mitral valve annulus |
US9180005B1 (en) | 2014-07-17 | 2015-11-10 | Millipede, Inc. | Adjustable endolumenal mitral valve ring |
US10695160B2 (en) | 2014-07-17 | 2020-06-30 | Boston Scientific Scimed, Inc. | Adjustable endolumenal implant for reshaping the mitral valve annulus |
US9615926B2 (en) | 2014-07-17 | 2017-04-11 | Millipede, Inc. | Adjustable endolumenal implant for reshaping the mitral valve annulus |
US10195026B2 (en) | 2014-07-22 | 2019-02-05 | Edwards Lifesciences Corporation | Mitral valve anchoring |
US11065112B2 (en) | 2014-08-18 | 2021-07-20 | W. L. Gore & Associates, Inc. | Frame with integral sewing cuff for prosthetic valves |
US10314697B2 (en) | 2014-08-18 | 2019-06-11 | W. L. Gore & Associates, Inc. | Frame with integral sewing cuff for prosthetic valves |
US10058424B2 (en) | 2014-08-21 | 2018-08-28 | Edwards Lifesciences Corporation | Dual-flange prosthetic valve frame |
US11826252B2 (en) | 2014-08-21 | 2023-11-28 | Edwards Lifesciences Corporation | Dual-flange prosthetic valve frame |
US20210128300A1 (en) | 2014-08-21 | 2021-05-06 | Edwards Lifesciences Corporation | Dual-flange prosthetic valve frame |
US10881512B2 (en) | 2014-08-21 | 2021-01-05 | Edwards Lifesciences Corporation | Dual-flange prosthetic valve frame |
US11406493B2 (en) | 2014-09-12 | 2022-08-09 | Mitral Valve Technologies Sarl | Mitral repair and replacement devices and methods |
US11471276B2 (en) | 2014-09-15 | 2022-10-18 | W. L. Gore & Associates, Inc. | Prosthetic heart valve with retention elements |
US10342659B2 (en) | 2014-09-15 | 2019-07-09 | W. L. Gore & Associates, Inc. | Prosthetic heart valve with retention elements |
AU2020210253B2 (en) * | 2014-12-18 | 2022-01-27 | Edwards Lifesciences Corporation | Prosthetic valves with mechanically coupled leaflets |
EP3718510A1 (en) * | 2014-12-18 | 2020-10-07 | W. L. Gore & Associates, Inc. | Prosthetic valves with mechanically coupled leaflets |
WO2016100913A1 (en) * | 2014-12-18 | 2016-06-23 | W.L. Gore & Associates, Inc. | Prosthetic valves with mechanically coupled leaflets |
US10653521B2 (en) | 2014-12-18 | 2020-05-19 | W. L. Gore & Associates, Inc. | Prosthetic valves with mechanically coupled leaflets |
AU2015364334B2 (en) * | 2014-12-18 | 2018-11-01 | Edwards Lifesciences Corporation | Prosthetic valves with mechanically coupled leaflets |
US9937037B2 (en) | 2014-12-18 | 2018-04-10 | W. L. Gore & Associates, Inc. | Prosthetic valved conduits with mechanically coupled leaflets |
CN109758266A (en) * | 2014-12-18 | 2019-05-17 | W.L.戈尔及同仁股份有限公司 | The prosthetic valve of leaflet with mechanical attachment |
CN107106294A (en) * | 2014-12-18 | 2017-08-29 | W.L.戈尔及同仁股份有限公司 | The prosthetic valve of leaflet with mechanical attachment |
US9855141B2 (en) | 2014-12-18 | 2018-01-02 | W. L. Gore & Associates, Inc. | Prosthetic valves with mechanically coupled leaflets |
US10980633B2 (en) | 2014-12-18 | 2021-04-20 | W. L. Gore & Associates, Inc. | Prosthetic valved conduits with mechanically coupled leaflets |
US10786351B2 (en) | 2015-01-07 | 2020-09-29 | Tendyne Holdings, Inc. | Prosthetic mitral valves and apparatus and methods for delivery of same |
US10610356B2 (en) | 2015-02-05 | 2020-04-07 | Tendyne Holdings, Inc. | Expandable epicardial pads and devices and methods for delivery of same |
US11918462B2 (en) | 2015-02-13 | 2024-03-05 | Boston Scientific Scimed, Inc. | Valve replacement using moveable restraints and angled struts |
US9848983B2 (en) | 2015-02-13 | 2017-12-26 | Millipede, Inc. | Valve replacement using rotational anchors |
US10258466B2 (en) | 2015-02-13 | 2019-04-16 | Millipede, Inc. | Valve replacement using moveable restrains and angled struts |
US10792471B2 (en) | 2015-04-10 | 2020-10-06 | Edwards Lifesciences Corporation | Expandable sheath |
US11406796B2 (en) | 2015-04-10 | 2022-08-09 | Edwards Lifesciences Corporation | Expandable sheath |
US10327896B2 (en) | 2015-04-10 | 2019-06-25 | Edwards Lifesciences Corporation | Expandable sheath with elastomeric cross sectional portions |
US11420026B2 (en) | 2015-04-10 | 2022-08-23 | Edwards Lifesciences Corporation | Expandable sheath |
US10667905B2 (en) | 2015-04-16 | 2020-06-02 | Tendyne Holdings, Inc. | Apparatus and methods for delivery, repositioning, and retrieval of transcatheter prosthetic valves |
US10064718B2 (en) | 2015-04-16 | 2018-09-04 | Edwards Lifesciences Corporation | Low-profile prosthetic heart valve for replacing a mitral valve |
US10010417B2 (en) | 2015-04-16 | 2018-07-03 | Edwards Lifesciences Corporation | Low-profile prosthetic heart valve for replacing a mitral valve |
US10624736B2 (en) | 2015-04-16 | 2020-04-21 | Edwards Lifesciences Corporation | Low-profile prosthetic heart valve for replacing a mitral valve |
US11523902B2 (en) | 2015-04-16 | 2022-12-13 | Tendyne Holdings, Inc. | Apparatus and methods for delivery, repositioning, and retrieval of transcatheter prosthetic valves |
US10709555B2 (en) | 2015-05-01 | 2020-07-14 | Jenavalve Technology, Inc. | Device and method with reduced pacemaker rate in heart valve replacement |
US11337800B2 (en) | 2015-05-01 | 2022-05-24 | Jenavalve Technology, Inc. | Device and method with reduced pacemaker rate in heart valve replacement |
US11318012B2 (en) | 2015-09-18 | 2022-05-03 | Tendyne Holdings, Inc. | Apparatus and methods for delivery of prosthetic mitral valve |
US10327894B2 (en) | 2015-09-18 | 2019-06-25 | Tendyne Holdings, Inc. | Methods for delivery of prosthetic mitral valves |
US10335275B2 (en) | 2015-09-29 | 2019-07-02 | Millipede, Inc. | Methods for delivery of heart valve devices using intravascular ultrasound imaging |
US10470876B2 (en) | 2015-11-10 | 2019-11-12 | Edwards Lifesciences Corporation | Transcatheter heart valve for replacing natural mitral valve |
US10376364B2 (en) | 2015-11-10 | 2019-08-13 | Edwards Lifesciences Corporation | Implant delivery capsule |
US10555813B2 (en) | 2015-11-17 | 2020-02-11 | Boston Scientific Scimed, Inc. | Implantable device and delivery system for reshaping a heart valve annulus |
US11096782B2 (en) | 2015-12-03 | 2021-08-24 | Tendyne Holdings, Inc. | Frame features for prosthetic mitral valves |
US10610358B2 (en) | 2015-12-28 | 2020-04-07 | Tendyne Holdings, Inc. | Atrial pocket closures for prosthetic heart valves |
US11464629B2 (en) | 2015-12-28 | 2022-10-11 | Tendyne Holdings, Inc. | Atrial pocket closures for prosthetic heart valves |
US10722354B2 (en) | 2016-02-12 | 2020-07-28 | Edwards Lifesciences Corporation | Prosthetic heart valve having multi-level sealing member |
US11744700B2 (en) | 2016-02-12 | 2023-09-05 | Edwards Lifesciences Corporation | Prosthetic heart valve having multi-level sealing member |
US10179043B2 (en) | 2016-02-12 | 2019-01-15 | Edwards Lifesciences Corporation | Prosthetic heart valve having multi-level sealing member |
US10517722B2 (en) | 2016-03-24 | 2019-12-31 | Edwards Lifesciences Corporation | Delivery system for prosthetic heart valve |
US11116629B2 (en) | 2016-03-24 | 2021-09-14 | Edwards Lifesciences Corporation | Delivery system for prosthetic heart valve |
US11253354B2 (en) | 2016-05-03 | 2022-02-22 | Tendyne Holdings, Inc. | Apparatus and methods for anterior valve leaflet management |
US10470877B2 (en) | 2016-05-03 | 2019-11-12 | Tendyne Holdings, Inc. | Apparatus and methods for anterior valve leaflet management |
US11065138B2 (en) | 2016-05-13 | 2021-07-20 | Jenavalve Technology, Inc. | Heart valve prosthesis delivery system and method for delivery of heart valve prosthesis with introducer sheath and loading system |
US11039921B2 (en) | 2016-06-13 | 2021-06-22 | Tendyne Holdings, Inc. | Sequential delivery of two-part prosthetic mitral valve |
US11701226B2 (en) | 2016-06-30 | 2023-07-18 | Tendyne Holdings, Inc. | Prosthetic heart valves and apparatus and methods for delivery of same |
US11090157B2 (en) | 2016-06-30 | 2021-08-17 | Tendyne Holdings, Inc. | Prosthetic heart valves and apparatus and methods for delivery of same |
US11065116B2 (en) | 2016-07-12 | 2021-07-20 | Tendyne Holdings, Inc. | Apparatus and methods for trans-septal retrieval of prosthetic heart valves |
US11096781B2 (en) | 2016-08-01 | 2021-08-24 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US11872125B2 (en) | 2016-08-01 | 2024-01-16 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US11806234B2 (en) | 2016-08-01 | 2023-11-07 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US10463484B2 (en) | 2016-11-17 | 2019-11-05 | Edwards Lifesciences Corporation | Prosthetic heart valve having leaflet inflow below frame |
US11484406B2 (en) | 2016-11-17 | 2022-11-01 | Edwards Lifesciences Corporation | Prosthetic heart valve having leaflet inflow below frame |
US10973631B2 (en) | 2016-11-17 | 2021-04-13 | Edwards Lifesciences Corporation | Crimping accessory device for a prosthetic valve |
US11344408B2 (en) | 2016-12-06 | 2022-05-31 | Edwards Lifesciences Corporation | Mechanically expanding heart valve and delivery apparatus therefor |
US10603165B2 (en) | 2016-12-06 | 2020-03-31 | Edwards Lifesciences Corporation | Mechanically expanding heart valve and delivery apparatus therefor |
US11654023B2 (en) | 2017-01-23 | 2023-05-23 | Edwards Lifesciences Corporation | Covered prosthetic heart valve |
US11185406B2 (en) | 2017-01-23 | 2021-11-30 | Edwards Lifesciences Corporation | Covered prosthetic heart valve |
US11938021B2 (en) | 2017-01-23 | 2024-03-26 | Edwards Lifesciences Corporation | Covered prosthetic heart valve |
US11013600B2 (en) | 2017-01-23 | 2021-05-25 | Edwards Lifesciences Corporation | Covered prosthetic heart valve |
US11197754B2 (en) | 2017-01-27 | 2021-12-14 | Jenavalve Technology, Inc. | Heart valve mimicry |
US10548731B2 (en) | 2017-02-10 | 2020-02-04 | Boston Scientific Scimed, Inc. | Implantable device and delivery system for reshaping a heart valve annulus |
US11135056B2 (en) | 2017-05-15 | 2021-10-05 | Edwards Lifesciences Corporation | Devices and methods of commissure formation for prosthetic heart valve |
US11026781B2 (en) | 2017-05-22 | 2021-06-08 | Edwards Lifesciences Corporation | Valve anchor and installation method |
US11883281B2 (en) | 2017-05-31 | 2024-01-30 | Edwards Lifesciences Corporation | Sealing member for prosthetic heart valve |
US10869759B2 (en) | 2017-06-05 | 2020-12-22 | Edwards Lifesciences Corporation | Mechanically expandable heart valve |
US11026785B2 (en) | 2017-06-05 | 2021-06-08 | Edwards Lifesciences Corporation | Mechanically expandable heart valve |
US11717400B2 (en) | 2017-06-05 | 2023-08-08 | Edwards Lifesciences Corporation | Mechanically expandable heart valve |
US11154399B2 (en) | 2017-07-13 | 2021-10-26 | Tendyne Holdings, Inc. | Prosthetic heart valves and apparatus and methods for delivery of same |
US11547544B2 (en) | 2017-07-18 | 2023-01-10 | Edwards Lifesciences Corporation | Transcatheter heart valve storage container and crimping mechanism |
US10918473B2 (en) | 2017-07-18 | 2021-02-16 | Edwards Lifesciences Corporation | Transcatheter heart valve storage container and crimping mechanism |
US11013595B2 (en) | 2017-08-11 | 2021-05-25 | Edwards Lifesciences Corporation | Sealing element for prosthetic heart valve |
US11083575B2 (en) | 2017-08-14 | 2021-08-10 | Edwards Lifesciences Corporation | Heart valve frame design with non-uniform struts |
US10932903B2 (en) | 2017-08-15 | 2021-03-02 | Edwards Lifesciences Corporation | Skirt assembly for implantable prosthetic valve |
US10898319B2 (en) | 2017-08-17 | 2021-01-26 | Edwards Lifesciences Corporation | Sealing member for prosthetic heart valve |
US11857411B2 (en) | 2017-08-18 | 2024-01-02 | Edwards Lifesciences Corporation | Pericardial sealing member for prosthetic heart valve |
US10722353B2 (en) | 2017-08-21 | 2020-07-28 | Edwards Lifesciences Corporation | Sealing member for prosthetic heart valve |
US11850148B2 (en) | 2017-08-21 | 2023-12-26 | Edwards Lifesciences Corporation | Sealing member for prosthetic heart valve |
US11191639B2 (en) | 2017-08-28 | 2021-12-07 | Tendyne Holdings, Inc. | Prosthetic heart valves with tether coupling features |
US10973629B2 (en) | 2017-09-06 | 2021-04-13 | Edwards Lifesciences Corporation | Sealing member for prosthetic heart valve |
US11147667B2 (en) | 2017-09-08 | 2021-10-19 | Edwards Lifesciences Corporation | Sealing member for prosthetic heart valve |
US10959842B2 (en) | 2017-09-12 | 2021-03-30 | W. L. Gore & Associates, Inc. | Leaflet frame attachment for prosthetic valves |
US11020221B2 (en) | 2017-09-27 | 2021-06-01 | W. L. Gore & Associates, Inc. | Prosthetic valve with expandable frame and associated systems and methods |
US11857412B2 (en) | 2017-09-27 | 2024-01-02 | Edwards Lifesciences Corporation | Prosthetic valve with expandable frame and associated systems and methods |
US11109963B2 (en) | 2017-09-27 | 2021-09-07 | W. L. Gore & Associates, Inc. | Prosthetic valves with mechanically coupled leaflets |
US11090153B2 (en) | 2017-10-13 | 2021-08-17 | W. L. Gore & Associates, Inc. | Telescoping prosthetic valve and delivery system |
US11123183B2 (en) | 2017-10-31 | 2021-09-21 | W. L. Gore & Associates, Inc. | Prosthetic heart valve |
US10987218B2 (en) | 2017-10-31 | 2021-04-27 | W. L. Gore & Associates, Inc. | Transcatheter deployment systems and associated methods |
US11439502B2 (en) | 2017-10-31 | 2022-09-13 | W. L. Gore & Associates, Inc. | Medical valve and leaflet promoting tissue ingrowth |
US11154397B2 (en) | 2017-10-31 | 2021-10-26 | W. L. Gore & Associates, Inc. | Jacket for surgical heart valve |
WO2019089163A1 (en) * | 2017-10-31 | 2019-05-09 | W. L. Gore & Associates, Inc. | Jacket for surgical heart valve |
CN111278388A (en) * | 2017-10-31 | 2020-06-12 | W.L.戈尔及同仁股份有限公司 | Surgical heart valve sheath |
US11318011B2 (en) | 2018-04-27 | 2022-05-03 | Edwards Lifesciences Corporation | Mechanically expandable heart valve with leaflet clamps |
US11446141B2 (en) | 2018-10-19 | 2022-09-20 | Edwards Lifesciences Corporation | Prosthetic heart valve having non-cylindrical frame |
USD926322S1 (en) | 2018-11-07 | 2021-07-27 | W. L. Gore & Associates, Inc. | Heart valve cover |
US11497601B2 (en) | 2019-03-01 | 2022-11-15 | W. L. Gore & Associates, Inc. | Telescoping prosthetic valve with retention element |
US11399932B2 (en) | 2019-03-26 | 2022-08-02 | Edwards Lifesciences Corporation | Prosthetic heart valve |
US11648110B2 (en) | 2019-12-05 | 2023-05-16 | Tendyne Holdings, Inc. | Braided anchor for mitral valve |
US11648114B2 (en) | 2019-12-20 | 2023-05-16 | Tendyne Holdings, Inc. | Distally loaded sheath and loading funnel |
US11678980B2 (en) | 2020-08-19 | 2023-06-20 | Tendyne Holdings, Inc. | Fully-transseptal apical pad with pulley for tensioning |
US11957576B2 (en) | 2020-10-05 | 2024-04-16 | Edwards Lifesciences Corporation | Expandable sheath for introducing an endovascular delivery device into a body |
US11951002B2 (en) | 2021-03-23 | 2024-04-09 | Tendyne Holdings, Inc. | Apparatus and methods for valve and tether fixation |
US11951003B2 (en) | 2021-06-04 | 2024-04-09 | Edwards Lifesciences Corporation | Mechanically expandable heart valve |
US11957582B2 (en) | 2021-09-07 | 2024-04-16 | Edwards Lifesciences Corporation | Prosthetic heart valve and delivery apparatus |
US11950999B2 (en) | 2021-10-06 | 2024-04-09 | Edwards Lifesciences Corporation | Everting transcatheter valve and methods |
US11951000B2 (en) | 2022-08-04 | 2024-04-09 | Mitral Valve Technologies Sarl | Mitral repair and replacement devices and methods |
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EP1117354A1 (en) | 2001-07-25 |
JP2002525169A (en) | 2002-08-13 |
US6334873B1 (en) | 2002-01-01 |
CN1328436A (en) | 2001-12-26 |
US20020026238A1 (en) | 2002-02-28 |
AU6259499A (en) | 2000-04-17 |
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