WO2000054745A3 - Devices and methods for pain management - Google Patents
Devices and methods for pain management Download PDFInfo
- Publication number
- WO2000054745A3 WO2000054745A3 PCT/US2000/007068 US0007068W WO0054745A3 WO 2000054745 A3 WO2000054745 A3 WO 2000054745A3 US 0007068 W US0007068 W US 0007068W WO 0054745 A3 WO0054745 A3 WO 0054745A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- drug
- site
- formulation
- drug formulation
- fentanyl
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0069—Devices for implanting pellets, e.g. markers or solid medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4468—Non condensed piperidines, e.g. piperocaine having a nitrogen directly attached in position 4, e.g. clebopride, fentanyl
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4535—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a heterocyclic ring having sulfur as a ring hetero atom, e.g. pizotifen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
- A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
Abstract
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU37561/00A AU769314B2 (en) | 1999-03-18 | 2000-03-16 | Devices and methods for pain management |
CA2363705A CA2363705C (en) | 1999-03-18 | 2000-03-16 | Devices and methods for pain management |
EP00916460A EP1162972A2 (en) | 1999-03-18 | 2000-03-16 | Devices and methods for pain management |
JP2000604823A JP4234908B2 (en) | 1999-03-18 | 2000-03-16 | Apparatus and method for pain treatment |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12558999P | 1999-03-18 | 1999-03-18 | |
US60/125,589 | 1999-03-18 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2000054745A2 WO2000054745A2 (en) | 2000-09-21 |
WO2000054745A3 true WO2000054745A3 (en) | 2000-11-30 |
Family
ID=22420446
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2000/007068 WO2000054745A2 (en) | 1999-03-18 | 2000-03-16 | Devices and methods for pain management |
Country Status (6)
Country | Link |
---|---|
US (6) | US6541021B1 (en) |
EP (1) | EP1162972A2 (en) |
JP (2) | JP4234908B2 (en) |
AU (1) | AU769314B2 (en) |
CA (1) | CA2363705C (en) |
WO (1) | WO2000054745A2 (en) |
Cited By (4)
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US8889174B1 (en) | 2001-06-22 | 2014-11-18 | Durect Corporation | Zero-order prolonged release coaxial implants |
US9526763B2 (en) | 2005-02-03 | 2016-12-27 | Intarcia Therapeutics Inc. | Solvent/polymer solutions as suspension vehicles |
US9539200B2 (en) | 2005-02-03 | 2017-01-10 | Intarcia Therapeutics Inc. | Two-piece, internal-channel osmotic delivery system flow modulator |
US9572889B2 (en) | 2008-02-13 | 2017-02-21 | Intarcia Therapeutics, Inc. | Devices, formulations, and methods for delivery of multiple beneficial agents |
Families Citing this family (91)
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GB9707934D0 (en) * | 1997-04-18 | 1997-06-04 | Danbiosyst Uk | Improved delivery of drugs to mucosal surfaces |
US7081133B2 (en) | 1999-01-19 | 2006-07-25 | Carbomedics Inc. | Antibiotic treated implantable medical devices |
US6541021B1 (en) * | 1999-03-18 | 2003-04-01 | Durect Corporation | Devices and methods for pain management |
US6835194B2 (en) * | 1999-03-18 | 2004-12-28 | Durect Corporation | Implantable devices and methods for treatment of pain by delivery of fentanyl and fentanyl congeners |
US6464688B1 (en) | 2000-02-15 | 2002-10-15 | Microsolutions, Inc. | Osmotic pump delivery system with flexible drug compartment |
US6471688B1 (en) | 2000-02-15 | 2002-10-29 | Microsolutions, Inc. | Osmotic pump drug delivery systems and methods |
US6616652B1 (en) | 2000-02-15 | 2003-09-09 | Microsolutions, Inc. | Osmotic pump delivery system with pre-hydrated membrane(s) and/or primable catheter |
CA2402865A1 (en) * | 2000-03-10 | 2001-09-20 | Durect Corporation | Opioid formulations |
US7074803B2 (en) | 2001-03-02 | 2006-07-11 | Durect Corporation | Opioid formulations |
ES2427976T5 (en) | 2000-07-31 | 2022-04-13 | Takeda Pharma As | Composition of fentanyl salt for nasal administration |
AU2001296770A1 (en) * | 2000-10-06 | 2002-04-15 | Durect Corporation | Devices and methods for management of inflammation |
US6632217B2 (en) | 2001-04-19 | 2003-10-14 | Microsolutions, Inc. | Implantable osmotic pump |
US20050101942A1 (en) * | 2001-09-17 | 2005-05-12 | Gillis Edward M. | Device and method for accurate delivery of an active agent |
US6703398B2 (en) * | 2001-11-26 | 2004-03-09 | Oliver Yoa-Pu Hu | Orally administered analgesic compositions containing nalbuphine |
US20030098661A1 (en) * | 2001-11-29 | 2003-05-29 | Ken Stewart-Smith | Control system for vehicle seats |
US20030159702A1 (en) * | 2002-01-21 | 2003-08-28 | Lindell Katarina E.A. | Formulation and use manufacture thereof |
AU2003214171A1 (en) | 2002-03-12 | 2003-09-29 | Harold Brem | Method for treating diabetic ulcers |
US7666876B2 (en) * | 2002-03-19 | 2010-02-23 | Vernalis (R&D) Limited | Buprenorphine formulations for intranasal delivery |
JP4668611B2 (en) * | 2002-05-31 | 2011-04-13 | タイタン ファーマシューティカルズ インコーポレイテッド | Implantable polymer device for sustained release of buprenorphine |
US7588564B2 (en) * | 2002-07-03 | 2009-09-15 | Pharmaco Kinesis Corporation | Apparatus for piezoelectric layer-wise pump and valve for use in local administration of biological response modifiers and therapeutic agents |
US7235164B2 (en) * | 2002-10-18 | 2007-06-26 | Eksigent Technologies, Llc | Electrokinetic pump having capacitive electrodes |
US7517440B2 (en) | 2002-07-17 | 2009-04-14 | Eksigent Technologies Llc | Electrokinetic delivery systems, devices and methods |
US20060264262A1 (en) * | 2002-07-17 | 2006-11-23 | Robert Toth | Bowling tournament method |
AU2003301406A1 (en) * | 2002-10-16 | 2004-05-04 | Durect Corporation | Apparatus and methods for activating a delivery device |
US20040102476A1 (en) * | 2002-11-25 | 2004-05-27 | Chan Tai Wah | High concentration formulations of opioids and opioid derivatives |
US7731947B2 (en) | 2003-11-17 | 2010-06-08 | Intarcia Therapeutics, Inc. | Composition and dosage form comprising an interferon particle formulation and suspending vehicle |
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CN1777426A (en) | 2003-03-31 | 2006-05-24 | 泰坦医药品公司 | Implantable polymeric device for sustained release of dopamine agonist |
CL2004000696A1 (en) | 2003-03-31 | 2005-05-20 | Alza Corp | OSMOTIC PUMP, IS FORMED BY A CYLINDER COVER WITH A CAMERA THAT RECEIVES THE OSMOTIC AGENT, AN OPEN END THAT RECEIVES A SEMIPERMEABLE PLUG AND A VENTILATION HOLE IN THE SIDE WALL LOCATED NEXT TO THE OPEN END, FOR DISI |
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US7231839B2 (en) * | 2003-08-11 | 2007-06-19 | The Board Of Trustees Of The Leland Stanford Junior University | Electroosmotic micropumps with applications to fluid dispensing and field sampling |
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- 2000-03-16 EP EP00916460A patent/EP1162972A2/en not_active Withdrawn
- 2000-03-16 AU AU37561/00A patent/AU769314B2/en not_active Ceased
- 2000-03-16 WO PCT/US2000/007068 patent/WO2000054745A2/en active IP Right Grant
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-
2002
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2003
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-
2005
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2006
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2007
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Cited By (4)
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US8889174B1 (en) | 2001-06-22 | 2014-11-18 | Durect Corporation | Zero-order prolonged release coaxial implants |
US9526763B2 (en) | 2005-02-03 | 2016-12-27 | Intarcia Therapeutics Inc. | Solvent/polymer solutions as suspension vehicles |
US9539200B2 (en) | 2005-02-03 | 2017-01-10 | Intarcia Therapeutics Inc. | Two-piece, internal-channel osmotic delivery system flow modulator |
US9572889B2 (en) | 2008-02-13 | 2017-02-21 | Intarcia Therapeutics, Inc. | Devices, formulations, and methods for delivery of multiple beneficial agents |
Also Published As
Publication number | Publication date |
---|---|
AU769314B2 (en) | 2004-01-22 |
JP2006231070A (en) | 2006-09-07 |
US20040157884A1 (en) | 2004-08-12 |
US20080161356A1 (en) | 2008-07-03 |
JP4234908B2 (en) | 2009-03-04 |
CA2363705A1 (en) | 2000-09-21 |
US20050129737A1 (en) | 2005-06-16 |
JP5105760B2 (en) | 2012-12-26 |
US20080161357A1 (en) | 2008-07-03 |
US20030171401A1 (en) | 2003-09-11 |
AU3756100A (en) | 2000-10-04 |
EP1162972A2 (en) | 2001-12-19 |
WO2000054745A2 (en) | 2000-09-21 |
CA2363705C (en) | 2013-06-11 |
JP2002538895A (en) | 2002-11-19 |
US6541021B1 (en) | 2003-04-01 |
US6689373B2 (en) | 2004-02-10 |
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