WO2001008714A1 - Cartilage or bone matrix as a nucleic acid delivery vehicle - Google Patents
Cartilage or bone matrix as a nucleic acid delivery vehicle Download PDFInfo
- Publication number
- WO2001008714A1 WO2001008714A1 PCT/US2000/020630 US0020630W WO0108714A1 WO 2001008714 A1 WO2001008714 A1 WO 2001008714A1 US 0020630 W US0020630 W US 0020630W WO 0108714 A1 WO0108714 A1 WO 0108714A1
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- WO
- WIPO (PCT)
- Prior art keywords
- bone
- graft
- composition
- cartilage
- nucleic acid
- Prior art date
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
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- A61L27/3683—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
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-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2230/0063—Three-dimensional shapes
- A61F2230/0069—Three-dimensional shapes cylindrical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/258—Genetic materials, DNA, RNA, genes, vectors, e.g. plasmids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2430/00—Materials or treatment for tissue regeneration
- A61L2430/40—Preparation and treatment of biological tissue for implantation, e.g. decellularisation, cross-linking
Abstract
Description
Claims
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002379663A CA2379663A1 (en) | 1999-07-28 | 2000-07-28 | Cartilage or bone matrix as a nucleic acid delivery vehicle |
EP00952271A EP1202755A1 (en) | 1999-07-28 | 2000-07-28 | Cartilage or bone matrix as a nucleic acid delivery vehicle |
AU64998/00A AU6499800A (en) | 1999-07-28 | 2000-07-28 | Cartilage or bone matrix as a nucleic acid delivery vehicle |
JP2001513444A JP2003505205A (en) | 1999-07-28 | 2000-07-28 | Cartilage or bone matrix as a nucleic acid delivery vehicle |
MXPA02000877A MXPA02000877A (en) | 1999-07-28 | 2000-07-28 | Cartilage or bone matrix as a nucleic acid delivery vehicle. |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36320899A | 1999-07-28 | 1999-07-28 | |
US09/363,208 | 1999-07-28 | ||
US58599700A | 2000-06-02 | 2000-06-02 | |
US09/585,997 | 2000-06-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2001008714A1 true WO2001008714A1 (en) | 2001-02-08 |
Family
ID=27001962
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2000/020630 WO2001008714A1 (en) | 1999-07-28 | 2000-07-28 | Cartilage or bone matrix as a nucleic acid delivery vehicle |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1202755A1 (en) |
JP (1) | JP2003505205A (en) |
AU (1) | AU6499800A (en) |
CA (1) | CA2379663A1 (en) |
MX (1) | MXPA02000877A (en) |
WO (1) | WO2001008714A1 (en) |
Cited By (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002009644A2 (en) * | 2000-07-31 | 2002-02-07 | Cornell Research Foundation, Inc. | Angiogenic and osteogenic proteins for use in enhancing bone density and formation |
FR2812553A1 (en) * | 2000-07-19 | 2002-02-08 | Geistlich Soehne Ag | Bone mineral product and collagen combination for repair of injured joints has porous bone mineral particles derived from natural bone having a crystal structure that of natural bone and being free from all endogenous organic material |
WO2002098329A1 (en) * | 2001-05-31 | 2002-12-12 | Bioteck Srl | Biomedical graft for skeletal structures |
WO2002098332A1 (en) * | 2001-02-16 | 2002-12-12 | Sulzer Spine-Tech Inc. | Bone implants and methods |
EP1283063A1 (en) * | 2001-08-10 | 2003-02-12 | Ed. Geistlich Söhne Ag Für Chemische Industrie | Collagen matrix for tissue regeneration containing therapeutic genetic material |
WO2002065957A3 (en) * | 2001-02-16 | 2003-04-17 | David A Hanson | Bone implants and methods |
FR2866237A1 (en) * | 2004-02-13 | 2005-08-19 | Biobank | Treating bone tissue, to form lipid- and virus-free implantable biomaterial, by treating successively with supercritical carbon dioxide, aqueous hydrogen peroxide, aqueous sodium hydroxide and ethanol |
WO2008064840A1 (en) | 2006-11-30 | 2008-06-05 | Markus Schlee | Method for producing an implant |
US8501396B2 (en) | 2001-11-05 | 2013-08-06 | Medgenics Medical Israel Ltd. | Dermal micro-organs, methods and apparatuses for producing and using the same |
US8530149B2 (en) | 2001-11-05 | 2013-09-10 | Medgenics Medical Israel Ltd | Dermal micro-organs, methods and apparatuses for producing and using the same |
US8685635B2 (en) | 2002-11-05 | 2014-04-01 | Medgenics Medical Israel Ltd. | Dermal micro-organs, methods and apparatuses for producing and using the same |
US8858981B2 (en) | 1997-10-10 | 2014-10-14 | Ed. Geistlich Soehne Fuer Chemistrie Industrie | Bone healing material comprising matrix carrying bone-forming cells |
US8877175B2 (en) | 2006-09-14 | 2014-11-04 | Medgenics Medical Israel Ltd. | Long lasting drug formulations |
US8911763B2 (en) | 1997-10-10 | 2014-12-16 | Ed. Geistlich Soehne Ag Fuer Chemistrie Industrie | Collagen carrier of therapeutic genetic material and method |
US9034315B2 (en) | 1997-10-10 | 2015-05-19 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Cell-charged multi-layer collagen membrane |
US9107896B2 (en) | 2001-11-05 | 2015-08-18 | Medgenics Medical Israel Ltd. | Dermal micro-organs, methods and apparatuses for producing and using the same |
US9127084B2 (en) | 2006-09-14 | 2015-09-08 | Medgenics Medical Israel Ltd. | Long lasting drug formulations |
US9155749B2 (en) | 2006-09-14 | 2015-10-13 | Medgenics Medical Israel Ltd. | Long lasting drug formulations |
US9265609B2 (en) | 2013-01-08 | 2016-02-23 | Warsaw Orthopedic, Inc. | Osteograft implant |
US9757330B2 (en) | 2013-10-18 | 2017-09-12 | Industrial Technology Research Institute | Recipe for in-situ gel, and implant, drug delivery system formed thereby |
US10172651B2 (en) | 2012-10-25 | 2019-01-08 | Warsaw Orthopedic, Inc. | Cortical bone implant |
CN111492223A (en) * | 2017-12-29 | 2020-08-04 | 豪夫迈·罗氏有限公司 | Tissue sample preparation system |
US11369473B2 (en) | 2019-04-08 | 2022-06-28 | Loubert S. Suddaby | Extended release immunomodulatory implant to facilitate bone morphogenesis |
US11779683B2 (en) | 2019-04-08 | 2023-10-10 | Loubert S. Suddaby | Extended release immunomodulatory implant to facilitate bone morphogenesis |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060111779A1 (en) * | 2004-11-22 | 2006-05-25 | Orthopedic Development Corporation, A Florida Corporation | Minimally invasive facet joint fusion |
US20100023129A1 (en) * | 2008-07-22 | 2010-01-28 | Guo-Feng Xu | Jawbone prosthesis and method of manufacture |
DE102010048710B4 (en) * | 2010-03-30 | 2013-05-23 | 3T Textiltechnologietransfer Gmbh | Implant with a sandwich structure |
WO2014019672A1 (en) * | 2012-07-31 | 2014-02-06 | Geistlich Pharma Ag | Hydrophilic phosphate group containing dehydrated partially purified bone replacement material |
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-
2000
- 2000-07-28 JP JP2001513444A patent/JP2003505205A/en active Pending
- 2000-07-28 WO PCT/US2000/020630 patent/WO2001008714A1/en not_active Application Discontinuation
- 2000-07-28 MX MXPA02000877A patent/MXPA02000877A/en unknown
- 2000-07-28 EP EP00952271A patent/EP1202755A1/en not_active Withdrawn
- 2000-07-28 CA CA002379663A patent/CA2379663A1/en not_active Abandoned
- 2000-07-28 AU AU64998/00A patent/AU6499800A/en not_active Abandoned
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US4820305A (en) | 1986-11-03 | 1989-04-11 | Harms Juergen | Place holder, in particular for a vertebra body |
US4878915A (en) | 1987-01-22 | 1989-11-07 | Brantigan John W | Surgical prosthetic implant facilitating vertebral interbody fusion |
US5670336A (en) * | 1988-04-08 | 1997-09-23 | Stryker Corporation | Method for recombinant production of osteogenic protein |
US5015247A (en) | 1988-06-13 | 1991-05-14 | Michelson Gary K | Threaded spinal implant |
US4961740B1 (en) | 1988-10-17 | 1997-01-14 | Surgical Dynamics Inc | V-thread fusion cage and method of fusing a bone joint |
US4961740A (en) | 1988-10-17 | 1990-10-09 | Surgical Dynamics, Inc. | V-thread fusion cage and method of fusing a bone joint |
US5026373A (en) | 1988-10-17 | 1991-06-25 | Surgical Dynamics, Inc. | Surgical method and apparatus for fusing adjacent bone structures |
US5044104A (en) | 1989-04-13 | 1991-09-03 | Rehau Ag & Co. | Label mounting apparatus |
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US5147402A (en) | 1990-12-05 | 1992-09-15 | Sulzer Brothers Limited | Implant for ingrowth of osseous tissue |
US5192327A (en) | 1991-03-22 | 1993-03-09 | Brantigan John W | Surgical prosthetic implant for vertebrae |
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WO1998056433A1 (en) * | 1997-06-11 | 1998-12-17 | Sdgi Holdings, Inc. | Bone graft composites and spacers |
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Cited By (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8911763B2 (en) | 1997-10-10 | 2014-12-16 | Ed. Geistlich Soehne Ag Fuer Chemistrie Industrie | Collagen carrier of therapeutic genetic material and method |
US8858981B2 (en) | 1997-10-10 | 2014-10-14 | Ed. Geistlich Soehne Fuer Chemistrie Industrie | Bone healing material comprising matrix carrying bone-forming cells |
US9034315B2 (en) | 1997-10-10 | 2015-05-19 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Cell-charged multi-layer collagen membrane |
NL1018560C2 (en) * | 2000-07-19 | 2003-08-19 | Geistlich Soehne Ag | Combination of bone material and collagen for repairing damaged joints. |
FR2812553A1 (en) * | 2000-07-19 | 2002-02-08 | Geistlich Soehne Ag | Bone mineral product and collagen combination for repair of injured joints has porous bone mineral particles derived from natural bone having a crystal structure that of natural bone and being free from all endogenous organic material |
ES2195731A1 (en) * | 2000-07-19 | 2003-12-01 | Geistlich Soehne Ag | Bone material and collagen combination for repair of injured joints |
US6939540B1 (en) | 2000-07-31 | 2005-09-06 | Cornell Research Foundation, Inc. | Method of enhancing bone density |
WO2002009644A3 (en) * | 2000-07-31 | 2003-02-27 | Cornell Res Foundation Inc | Angiogenic and osteogenic proteins for use in enhancing bone density and formation |
WO2002009644A2 (en) * | 2000-07-31 | 2002-02-07 | Cornell Research Foundation, Inc. | Angiogenic and osteogenic proteins for use in enhancing bone density and formation |
WO2002098332A1 (en) * | 2001-02-16 | 2002-12-12 | Sulzer Spine-Tech Inc. | Bone implants and methods |
WO2002065957A3 (en) * | 2001-02-16 | 2003-04-17 | David A Hanson | Bone implants and methods |
WO2002098329A1 (en) * | 2001-05-31 | 2002-12-12 | Bioteck Srl | Biomedical graft for skeletal structures |
EP1283063A1 (en) * | 2001-08-10 | 2003-02-12 | Ed. Geistlich Söhne Ag Für Chemische Industrie | Collagen matrix for tissue regeneration containing therapeutic genetic material |
AU2002300450B2 (en) * | 2001-08-10 | 2007-04-05 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Collagen Carrier of Therapeutic Genetic Material, and Method |
US9468667B2 (en) | 2001-11-05 | 2016-10-18 | Medgenics Medical Israel Ltd. | Dermal micro-organs, methods and apparatuses for producing and using the same |
US8501396B2 (en) | 2001-11-05 | 2013-08-06 | Medgenics Medical Israel Ltd. | Dermal micro-organs, methods and apparatuses for producing and using the same |
US8530149B2 (en) | 2001-11-05 | 2013-09-10 | Medgenics Medical Israel Ltd | Dermal micro-organs, methods and apparatuses for producing and using the same |
US9107896B2 (en) | 2001-11-05 | 2015-08-18 | Medgenics Medical Israel Ltd. | Dermal micro-organs, methods and apparatuses for producing and using the same |
US8685635B2 (en) | 2002-11-05 | 2014-04-01 | Medgenics Medical Israel Ltd. | Dermal micro-organs, methods and apparatuses for producing and using the same |
US8771291B2 (en) | 2002-11-05 | 2014-07-08 | Medgenics Medical Israel Ltd. | Dermal micro-organs, methods and apparatuses for producing and using the same |
US9101595B2 (en) | 2002-11-05 | 2015-08-11 | Medgenics Medical Israel Ltd. | Dermal micro-organs, methods and apparatuses for producing and using the same |
US9572593B2 (en) | 2003-05-01 | 2017-02-21 | Medgenics Medical Israel Ltd. | Dermal micro-organs, methods and apparatuses for producing and using the same |
FR2866237A1 (en) * | 2004-02-13 | 2005-08-19 | Biobank | Treating bone tissue, to form lipid- and virus-free implantable biomaterial, by treating successively with supercritical carbon dioxide, aqueous hydrogen peroxide, aqueous sodium hydroxide and ethanol |
WO2005082432A1 (en) * | 2004-02-13 | 2005-09-09 | Biobank | Method for treating bone tissue and implantable biomaterials |
US9155749B2 (en) | 2006-09-14 | 2015-10-13 | Medgenics Medical Israel Ltd. | Long lasting drug formulations |
US8877175B2 (en) | 2006-09-14 | 2014-11-04 | Medgenics Medical Israel Ltd. | Long lasting drug formulations |
US9687564B2 (en) | 2006-09-14 | 2017-06-27 | Medgenics Medical Israel Ltd. | Long lasting drug formulations |
US9127084B2 (en) | 2006-09-14 | 2015-09-08 | Medgenics Medical Israel Ltd. | Long lasting drug formulations |
WO2008064840A1 (en) | 2006-11-30 | 2008-06-05 | Markus Schlee | Method for producing an implant |
EP2097046B1 (en) * | 2006-11-30 | 2013-04-24 | SCHLEE, Markus | Method for producing an implant |
US10172651B2 (en) | 2012-10-25 | 2019-01-08 | Warsaw Orthopedic, Inc. | Cortical bone implant |
US10820999B2 (en) | 2013-01-08 | 2020-11-03 | Warsaw Orthopedic, Inc. | Osteograft implant |
US9265609B2 (en) | 2013-01-08 | 2016-02-23 | Warsaw Orthopedic, Inc. | Osteograft implant |
US9949832B2 (en) | 2013-01-08 | 2018-04-24 | Warsaw Orthopedic, Inc. | Osteograft implant |
US9757330B2 (en) | 2013-10-18 | 2017-09-12 | Industrial Technology Research Institute | Recipe for in-situ gel, and implant, drug delivery system formed thereby |
CN111492223A (en) * | 2017-12-29 | 2020-08-04 | 豪夫迈·罗氏有限公司 | Tissue sample preparation system |
US11369473B2 (en) | 2019-04-08 | 2022-06-28 | Loubert S. Suddaby | Extended release immunomodulatory implant to facilitate bone morphogenesis |
US11779683B2 (en) | 2019-04-08 | 2023-10-10 | Loubert S. Suddaby | Extended release immunomodulatory implant to facilitate bone morphogenesis |
Also Published As
Publication number | Publication date |
---|---|
AU6499800A (en) | 2001-02-19 |
EP1202755A1 (en) | 2002-05-08 |
JP2003505205A (en) | 2003-02-12 |
CA2379663A1 (en) | 2001-02-08 |
MXPA02000877A (en) | 2002-08-06 |
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