WO2001010338A9 - Eye tracking and positioning system for a refractive laser system - Google Patents
Eye tracking and positioning system for a refractive laser systemInfo
- Publication number
- WO2001010338A9 WO2001010338A9 PCT/US2000/021882 US0021882W WO0110338A9 WO 2001010338 A9 WO2001010338 A9 WO 2001010338A9 US 0021882 W US0021882 W US 0021882W WO 0110338 A9 WO0110338 A9 WO 0110338A9
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- eye
- laser beam
- positioning system
- image
- eye tracking
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/008—Methods or devices for eye surgery using laser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/008—Methods or devices for eye surgery using laser
- A61F9/00802—Methods or devices for eye surgery using laser for photoablation
- A61F9/00804—Refractive treatments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/008—Methods or devices for eye surgery using laser
- A61F2009/00844—Feedback systems
- A61F2009/00846—Eyetracking
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/008—Methods or devices for eye surgery using laser
- A61F2009/00861—Methods or devices for eye surgery using laser adapted for treatment at a particular location
- A61F2009/00872—Cornea
Definitions
- This invention relates broadly to eye surgery. More particularly, this invention relates to refractive laser systems for eye surgery.
- the excimer laser refractive surgery field has exploded over the past few years with many new lasers systems to correct human vision.
- These systems use an ultraviolet excimer laser to change the shape of the cornea in a calculated pattern which makes it possible for the eye to focus properly.
- the laser is used to remove tissue from the cornea in order to flatten its shape.
- the correction of hyperopia is produced by steepening the cornea.
- the correction of astigmatism requires the laser to remove tissue in a more complex pattern. All of these procedures require precise shaping of the cornea which depends on accurate placement of the laser beam. Therefore, any eye movement can affect the placement of the laser beam.
- an eye tracking and positioning system for use with a refractive laser system which produces a laser for surgically reshaping the eye.
- the eye tracking and positioning system includes a means for capturing images of the eye, a computer, and a means for moving the patient relative to the laser beam.
- the computer preferably includes a video frame grabber which captures images from a camera of the laser system, and is programmed to perform an eye tracking algorithm with respect to the images .
- the eye tracking algorithm calculates the exact center of the eye pupil in the image, and compares the center with the desired location of the laser beam, as determined by a surgeon, with an image processing algorithm.
- the means for moving the patient is preferably a surgical bed, surgical chair, or headrest which is motorized to move the patient relative to the laser beam (as opposed to moving the laser beam relative to the patient) to make the necessary adjustment to the current position of the eye and thereby counter the movement of the eye.
- the eye tracking and positioning system of the invention may be retrofit to the existing broadbeam and scanning spot systems which do not already include eye tracking capability. Additionally, the eye tracking and positioning system may be provided as an integral part of new refractive laser surgery- systems .
- Figure 1 is a schematic view of a refractive laser system provided with the eye tracking and positioning system of the invention
- Figure 2 is a flow chart of the process of the invention.
- FIG. 3 is a schematic view of the patient positioning interface of the invention. DETAILED DESCRIPTION OF THE PREFERRED EMBODIMENTS
- a refractive laser system 10 is coupled to an eye tracking computer system 12 of the invention.
- the refractive laser system 10 includes a laser 14 coupled to a system processor 16, a joystick 18 coupled to the system processor 16 for positioning a surgical chair 42, and a surgical microscope 20 for viewing an eye of a patient seated in the surgical chair 42.
- the refractive laser system 10 also includes a video-out camera port 22 coupled to the microscope, and a footswitch port 24 and a surgical chair port 26.
- the eye tracking computer system 12 generally includes a video camera interface 30 which is coupled to the video-out port 22, a frame grabber 32, and an image tracking processor 34, preferably implementing a software algorithm described below.
- the computer system 12 also includes a footswitch interface 36 and a patient positioning interface 40.
- the footswitch interface 36 is coupled between the footswitch port 24 and a footswitch 38.
- the laser 14 is activated to emit a laser beam, as described in more detail below.
- the computer 12 also includes a patient positioning interface 40 which is coupled between the surgical chair port 26 and the surgical chair (or bed or headrest) 42.
- the surgical chair 42 is provided with motors capable of relatively rapidly repositioning the chair such that an eye of a patient in the chair is moved relative to a laser beam emitted by the laser 14.
- the video-out camera port 22 to which the video camera interface 30 is coupled is typically a microscope beam splitter optical port which permits users to attach cameras thereto for recording the surgery and audience viewing of the surgery.
- the eye tracking system 12 takes advantage of one of these microscope beam splitter optical ports in order to monitor the eye via a provided video camera.
- a provided video camera For example, in the VISXTM laser, an electronic output signal port connector is provided which is attached to an internal CCD camera.
- an electronic signal splitter can be attached at the output of the camera so the signal may be captured by the video camera interface 30.
- a separate camera (not shown) may be provided with the eye tracking system of the invention and added to the microscope beam splitter optical port in order to capture the images . That is, any number of methods and systems may be utilized to capture the image of the eye from the surgical microscope 20 used in performing the refractive laser surgery.
- the frame grabber 32 takes the signal from the video camera interface 30 and converts it to a digital signal, preferably in real-time.
- the frame grabber 32 can be configured to capture color, monochrome or infrared images at varying speeds .
- the digitized signal is then converted to a digital image matrix for processing. This conversion occurs at the rate of the camera (from a typical 30 Hz for color cameras to as fast as 800-Hz for monochrome cameras) .
- the image tracking processor 34 receives the digitized image from the frame grabber 32 and generally (1) processes the digitized image for laser beam center, (2) processes the digitized image for pupil recognition, (3) determines the center of the pupil, and (4) calculates the offset of the current eye pupil center from a surgeon-desired offset and drives the appropriate surgical chair motors .
- Each of the functions of the image tracking processor 34 are preferably performed by an algorithm carried out by the image tracking processor 34, and will now be described in more detail.
- the current image in the camera is digitally captured at 50 by the frame grabber 32 for processing.
- the digitized image is processed at 52 to determine a laser beam center (reference location) preferably by one of two methods. Both methods begin by monitoring the footswitch 38 during continuous acquisition of the eye image signal entering from the video camera interface 30.
- the center of the pupil is used as the laser beam center. That is, the surgeon positions the eye with respect to an alignment marker (e.g., a reticle appearing in the microscope 20 or displayed on a video monitor) . Positioning is performed by adjustment of the surgical chair 42 via movement of the joystick 18. Once the eye is properly positioned, the surgeon presses the footswitch 38 and the image tracking processor 34 uses the current eye pupil center as the laser beam center. The image tracking processor 34 then continues to the next step of actively tracking the eye pupil center and directing the surgical chair motors so that the laser beam and eye are properly relatively positioned.
- an alignment marker e.g., a reticle appearing in the microscope 20 or displayed on a video monitor
- the surgeon or a surgical technician uses a laser system alignment marker (e.g., a reticle or a visible laser diode spot) to designate the laser beam center.
- a laser system alignment marker e.g., a reticle or a visible laser diode spot
- This second method permits the laser beam to be centered away from the pupil center.
- the surgeon presses the footswitch 38 and the image tracking processor 34 captures the current image.
- this image is preferably then processed to highlight the alignment marker, which appears brighter than the pupil in a monochrome image, or appears as a different color than the pupil in a color image.
- the alignment marker is determined and its center is found and recorded as the desired laser beam center.
- a PC mouse cursor is used by the technician to mark the position of the reticle or the alignment spot.
- the coordinates of the mouse cursor are recorded as the desired laser beam center.
- the image tracking processor 34 then continues to the next step of actively tracking the eye pupil center and directing the surgical chair motors .
- the image tracking processor 34 next determines at 58 the eye pupil center. That is, once the desired laser beam reference location is determined at 54 or 56, the image tracking processor 34 begins to track the eye pupil center. There are several image processing methods that can be used to find the pupil and pupil center. One preferred method implemented by the image tracking processor 34 uses the contrast between the pupil and the iris to determine the pupil and then the center of the pupil by the following seven steps .
- the alignment marker is removed at 60 from the image.
- the alignment marker is useful to help determine the desired laser center beam, it does interfere with detection of the pupil.
- alignment marker removal from a monochrome image is preferably performed with a high order low pass filter.
- the marker is removed by ignoring the color plane that corresponds to its color (usually red) .
- the contrast between the pupil and the iris is enhanced. This is preferably done by applying a transfer function to the intensity values in the image to produce a bimodal histogram of intensity values.
- the transfer function increases the brightness and contrast in dark regions (the pupil) and decreases the contrast in brighter regions (iris) .
- the intensity values are preferably then reversed to produce a photometric negative of the image.
- the photometric image is used in the image processing steps which follow.
- a threshold function is applied to the photometric image at 64 to create a binary representation of the image which permits faster image processing.
- the threshold function replaces the image intensity values below some threshold value to black (a value of zero) while placing the intensity values above the threshold value to all white (a value of 256 in an 8- bit image representation); i.e., a binary representation of the image is created.
- the image of the pupil is now totally white against a black background.
- the binary representation is preferably further processed at 66 by a technique known as dilation.
- Dilation ensures that the pupil is a solid circular object. This step is preferred as sometimes the alignment marker, especially the reticle, will leave black holes or lines in the pupil area.
- the binary image undergoes a characterization process to determine a set of parametric values from the image. Since all pupils are nearly the same diameter (for recognition purposes) , the search of binary objects can be limited to a range defined by pupil diameters. This range is typically 2-3 millimeters. A search is then performed on the binary image for objects matching the criterion. Those objects found in this range are returned with several pieces of information. By limiting the field-of-view to the eye image, only one object, the pupil, will be detected. The information returned from this function include object area, width and height, and object center. The object center is used for the pupil center. The object width and height are used to apply a bounding circle around the displayed pupil during the tracking procedure.
- an offset calculation is made at 70 in which the object (pupil) center is compared against the previously defined laser beam center and differences are recorded. If, at 72, the difference is less than or equal to a surgeon preset value, i.e., a predetermined tracking zone, the surgical chair is not adjusted, the laser is permitted to operate, and the image tracking system 34 continues to receive, at 50, and process, at 52, 54 (or 56), 58, 60, 62, 64, 66, 68 and 70, images of the eye.
- a surgeon preset value i.e., a predetermined tracking zone
- the image tracking processor 34 sends a command to interrupt one stage (FSl in Fig. 3) of the footswitch 38, thus pausing the laser surgery procedure, and also repositions the patient at 76 by adjusting the surgical chair 42 in the proper direction, as described below. Then, once repositioned, the laser is again permitted to operate (i.e., the footswitch is reset) , and, at 50, the image tracking system 34 continues to receive and process images of the eye.
- the patient positioning interface 40 performs two functions: (1) adjustment of the chair 42 and patient to counter the eye motion and, if the eye center is outside the safety zone at 74, (2) interruption at 78 of the signal from the footswitch 38, as a safety measure. Each of these functions will now be described in more detail.
- an adjustment signal determined by the image tracking processor 34 is sent at 76 to the patient positioning interface 40 for adjustment of the surgical chair 42.
- the patient positioning interface 40 provides the appropriate signal to direct the chair motors.
- a DextaTM surgical chair well-known in the field of eye refractive surgery, utilizes relays to provide fixed voltages to positioning motors in the chair.
- four relays provide +X, -X, +Y, and -Y directional movement.
- Z directional control voltages may also be used.
- the relays are turned OFF or ON depending on the tracking adjustment required. Additionally or alternatively, variable control voltages may be supplied to the chair controller.
- the patient positioning interface 40 provides these variable voltages to the appropriate motors to adjust the eye position of the patient.
- Other beds or chairs used in this field have similar controls and may likewise be coupled to the patient positioning interface 40.
- the invention may be used with a headrest which includes motor control to appropriately adjust the eye position of the patient.
- interruption at 78 of a stage of the footswitch 38 pauses the laser procedure when the eye drifts outside the safety zone at 74. That FSl stage of the footswitch is re- enabled once the eye is returned to the safety zone by adjustment of the surgical chair.
- an eye tracking and positioning system for a refractive laser system and a method of tracking an eye and repositioning the eye relative to a laser beam. While particular embodiments of the invention have been described, it is not intended that the invention be limited thereto, as it is intended that the invention be as broad in scope as the art will allow and that the specification be read likewise. Thus, while particular functional systems have been disclosed, it will be appreciated that other functional systems may be used as well . That is, the image tracking processor and patient positioning interface may be combined in a single system or further divided to perform the required tasks of the invention. Furthermore, while a particular preferred method has been disclosed for tracking the pupil of the eye, it will be appreciated that other algorithms may be used.
- the eye center can be determined from a marker in a manner other than described above.
- an active infrared diode system places one or more small, collimated spots on the cornea, and an infrared detector system is then used to monitor the one or more spots. For example, three spots can be monitored to triangulate the center of the eye during eye movement.
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002381158A CA2381158A1 (en) | 1999-08-10 | 2000-08-10 | Eye tracking and positioning system for a refractive laser system |
AU68999/00A AU767927B2 (en) | 1999-08-10 | 2000-08-10 | Eye tracking and positioning system for a refractive laser system |
JP2001514867A JP2003506139A (en) | 1999-08-10 | 2000-08-10 | Eye tracking / positioning system for refractive laser systems |
EP00957367A EP1418856A4 (en) | 1999-08-10 | 2000-08-10 | Eye tracking and positioning system for a refractive laser system |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/371,195 US6280436B1 (en) | 1999-08-10 | 1999-08-10 | Eye tracking and positioning system for a refractive laser system |
US09/371,195 | 1999-08-10 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2001010338A2 WO2001010338A2 (en) | 2001-02-15 |
WO2001010338A3 WO2001010338A3 (en) | 2001-07-12 |
WO2001010338A9 true WO2001010338A9 (en) | 2002-09-06 |
Family
ID=23462914
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2000/021882 WO2001010338A2 (en) | 1999-08-10 | 2000-08-10 | Eye tracking and positioning system for a refractive laser system |
Country Status (6)
Country | Link |
---|---|
US (1) | US6280436B1 (en) |
EP (1) | EP1418856A4 (en) |
JP (1) | JP2003506139A (en) |
AU (1) | AU767927B2 (en) |
CA (1) | CA2381158A1 (en) |
WO (1) | WO2001010338A2 (en) |
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JP3828626B2 (en) * | 1996-12-27 | 2006-10-04 | 株式会社ニデック | Ophthalmic surgery equipment |
US5899857A (en) * | 1997-01-07 | 1999-05-04 | Wilk; Peter J. | Medical treatment method with scanner input |
US5947955A (en) * | 1997-09-12 | 1999-09-07 | Lasersight Technologies, Inc. | Active eye movement and positioning control device |
US5928221A (en) * | 1997-11-17 | 1999-07-27 | Coherent, Inc. | Fluence monitoring method for laser treatment of biological tissue |
US5982555A (en) * | 1998-01-20 | 1999-11-09 | University Of Washington | Virtual retinal display with eye tracking |
US6045227A (en) * | 1998-09-03 | 2000-04-04 | Visionrx.Com, Inc. | Multi-functional visual testing instrument |
US6149643A (en) * | 1998-09-04 | 2000-11-21 | Sunrise Technologies International, Inc. | Method and apparatus for exposing a human eye to a controlled pattern of radiation |
US6152599A (en) * | 1998-10-21 | 2000-11-28 | The University Of Texas Systems | Tomotherapy treatment table positioning device |
US6146375A (en) * | 1998-12-02 | 2000-11-14 | The University Of Michigan | Device and method for internal surface sclerostomy |
-
1999
- 1999-08-10 US US09/371,195 patent/US6280436B1/en not_active Expired - Fee Related
-
2000
- 2000-08-10 CA CA002381158A patent/CA2381158A1/en not_active Abandoned
- 2000-08-10 JP JP2001514867A patent/JP2003506139A/en active Pending
- 2000-08-10 AU AU68999/00A patent/AU767927B2/en not_active Ceased
- 2000-08-10 EP EP00957367A patent/EP1418856A4/en not_active Withdrawn
- 2000-08-10 WO PCT/US2000/021882 patent/WO2001010338A2/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
JP2003506139A (en) | 2003-02-18 |
EP1418856A2 (en) | 2004-05-19 |
US6280436B1 (en) | 2001-08-28 |
CA2381158A1 (en) | 2001-02-15 |
AU767927B2 (en) | 2003-11-27 |
WO2001010338A3 (en) | 2001-07-12 |
AU6899900A (en) | 2001-03-05 |
EP1418856A4 (en) | 2005-08-03 |
WO2001010338A2 (en) | 2001-02-15 |
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