WO2001036965A3 - Electric substance detectors comprising cellular material - Google Patents

Electric substance detectors comprising cellular material Download PDF

Info

Publication number
WO2001036965A3
WO2001036965A3 PCT/IB2000/001685 IB0001685W WO0136965A3 WO 2001036965 A3 WO2001036965 A3 WO 2001036965A3 IB 0001685 W IB0001685 W IB 0001685W WO 0136965 A3 WO0136965 A3 WO 0136965A3
Authority
WO
WIPO (PCT)
Prior art keywords
cellular material
container
fluid
detected
detection region
Prior art date
Application number
PCT/IB2000/001685
Other languages
French (fr)
Other versions
WO2001036965A2 (en
Inventor
Spiridon Kintzios
Original Assignee
Spiridon Kintzios
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Spiridon Kintzios filed Critical Spiridon Kintzios
Priority to EP00979828A priority Critical patent/EP1366353A2/en
Priority to AU17210/01A priority patent/AU1721001A/en
Priority to JP2001538802A priority patent/JP2003514539A/en
Priority to IL14972800A priority patent/IL149728A0/en
Publication of WO2001036965A2 publication Critical patent/WO2001036965A2/en
Publication of WO2001036965A3 publication Critical patent/WO2001036965A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/48707—Physical analysis of biological material of liquid biological material by electrical means

Abstract

There is provided a method for indicating the presence of a material to be detected in a fluid comprising: bringing the fluid containing the material to be detected into contact with a detection region containing cellular material; monitoring an electrical property across the detection region; and detecting the presence of the material by sensing at least a predetermined change in the electrical property across the detection region. Also provided is an apparatus for indicating the presence of a material to be detected in a fluid, comprising: a container capable of holding cellular material located within a predetermined region of said container, said container being adapted to enable a fluid to be brought into contact with cellular material held in said container; and a detector capable of sensing at least a predetermined change in an electric property across said predetermined region.
PCT/IB2000/001685 1999-11-19 2000-11-16 Electric substance detectors comprising cellular material WO2001036965A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP00979828A EP1366353A2 (en) 1999-11-19 2000-11-16 Electric substance detectors comprising cellular material
AU17210/01A AU1721001A (en) 1999-11-19 2000-11-16 Method for identifying biochemical material
JP2001538802A JP2003514539A (en) 1999-11-19 2000-11-16 Biochemical identification methods
IL14972800A IL149728A0 (en) 1999-11-19 2000-11-16 Method for identifying biochemical material

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GR990100398 1999-11-19
GR99100398 1999-11-19

Publications (2)

Publication Number Publication Date
WO2001036965A2 WO2001036965A2 (en) 2001-05-25
WO2001036965A3 true WO2001036965A3 (en) 2002-01-17

Family

ID=10943975

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2000/001685 WO2001036965A2 (en) 1999-11-19 2000-11-16 Electric substance detectors comprising cellular material

Country Status (6)

Country Link
EP (1) EP1366353A2 (en)
JP (1) JP2003514539A (en)
AU (1) AU1721001A (en)
GR (1) GR1003489B (en)
IL (1) IL149728A0 (en)
WO (1) WO2001036965A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9291549B2 (en) 2001-02-07 2016-03-22 Massachusetts Institute Of Technology Pathogen detection biosensor

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6248542B1 (en) 1997-12-09 2001-06-19 Massachusetts Institute Of Technology Optoelectronic sensor
ATE506452T1 (en) 2001-02-07 2011-05-15 Massachusetts Inst Technology OPTOELECTRONIC DETECTION SYSTEM
US7422860B2 (en) 2001-02-07 2008-09-09 Massachusetts Institute Of Technology Optoelectronic detection system
GR1005420B (en) * 2006-01-20 2007-01-31 Σπυριδων Ευαγγελου Κιντζιος Molecular identification through membrane-engineered cells (mime cells)
ES2672201T3 (en) * 2008-07-16 2018-06-13 Children's Medical Center Corporation Imitation device of organs with microchannels and methods of use

Citations (7)

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Publication number Priority date Publication date Assignee Title
US4343782A (en) * 1978-04-20 1982-08-10 Shapiro Howard M Cytological assay procedure
DE19540098A1 (en) * 1995-10-27 1997-04-30 Inst Chemo Biosensorik Method and multi-channel bio-sensor for multi-component analysis of mixtures
WO1997017426A1 (en) * 1995-11-08 1997-05-15 Trustees Of Boston University Cellular physiology workstations for automated data acquisition and perfusion control
WO1997049987A1 (en) * 1996-06-27 1997-12-31 Cellstat Technologies, Inc. High-throughput screening method and apparatus
WO1998023948A1 (en) * 1996-11-29 1998-06-04 The Board Of Trustees Of The Leland Stanford Junior University Arrays of independently-addressable supported fluid bilayer membranes and methods of use thereof
WO1998054294A1 (en) * 1997-05-30 1998-12-03 Board Of Trustees, Leland Stanford, Jr. University Microelectronic biosensor and method of monitoring cultured cells
WO1998055870A1 (en) * 1997-06-04 1998-12-10 A+ Science Invest Ab Detection of biologically active molecules by use of pre-activated cell-based biosensors in liquid-based separation systems

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4343782A (en) * 1978-04-20 1982-08-10 Shapiro Howard M Cytological assay procedure
DE19540098A1 (en) * 1995-10-27 1997-04-30 Inst Chemo Biosensorik Method and multi-channel bio-sensor for multi-component analysis of mixtures
WO1997017426A1 (en) * 1995-11-08 1997-05-15 Trustees Of Boston University Cellular physiology workstations for automated data acquisition and perfusion control
WO1997049987A1 (en) * 1996-06-27 1997-12-31 Cellstat Technologies, Inc. High-throughput screening method and apparatus
WO1998023948A1 (en) * 1996-11-29 1998-06-04 The Board Of Trustees Of The Leland Stanford Junior University Arrays of independently-addressable supported fluid bilayer membranes and methods of use thereof
WO1998054294A1 (en) * 1997-05-30 1998-12-03 Board Of Trustees, Leland Stanford, Jr. University Microelectronic biosensor and method of monitoring cultured cells
WO1998055870A1 (en) * 1997-06-04 1998-12-10 A+ Science Invest Ab Detection of biologically active molecules by use of pre-activated cell-based biosensors in liquid-based separation systems

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
IWATA M; KOMORI S; UNNO T; MINAMOTO N; OHASHI H: "Modification of membrane currents in mouse neuroblastoma cells following infection with rabies virus", BRITISH JOURNAL OF PHARMACOLOGY, vol. 126, April 1999 (1999-04-01), pages 1691 - 1698, XP000934183 *
MARTY J -L; LECA B; NOGUER T: "Biosensors for the detection of pesticides", ANALUSIS, vol. 26, July 1998 (1998-07-01) - August 1998 (1998-08-01), pages M144 - M149, XP000934103 *
RAWSON D M; WILLMER A J; TURNER A P F: "WHOLE-CELL BIOSENSORS FOR ENVIRONMENTAL MONITORING", BIOSENSORS, vol. 4, 1989, pages 299 - 312, XP000934099 *
SCHROTH P; SCHOENING M J; KORDOS P; LUETH H; SCHUETZ S; WEISSBECKER B; HUMMEL H E: "Insect-based BioFETs with improved signal characteristics", BIOSENSORS & BIOELECTRONICS, vol. 14, 15 March 1999 (1999-03-15), pages 303 - 308, XP000934104 *
SCHUETZ S; WEISSBECKER B; KOCH U T; HUMMEL H E: "Detection of volatiles released by diseased potato tubers using a biosensor on the basis of intact insect antennae", BIOSENSORS & BIOELECTRONICS, vol. 14, 1 February 1999 (1999-02-01), pages 221 - 228, XP000934109 *
WANG C ET AL: "Direct measurement of the influenza A virus M2 protein ion channel activity in mammalian cells", VIROLOGY,US,ACADEMIC PRESS,ORLANDO, vol. 205, no. 1, 1994, pages 133 - 140, XP002085469, ISSN: 0042-6822 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9291549B2 (en) 2001-02-07 2016-03-22 Massachusetts Institute Of Technology Pathogen detection biosensor

Also Published As

Publication number Publication date
JP2003514539A (en) 2003-04-22
IL149728A0 (en) 2002-11-10
WO2001036965A2 (en) 2001-05-25
GR1003489B (en) 2000-11-30
AU1721001A (en) 2001-05-30
EP1366353A2 (en) 2003-12-03

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