WO2001038873A3 - Devices and methods for detecting analytes using electrosensor having capture reagent - Google Patents

Devices and methods for detecting analytes using electrosensor having capture reagent Download PDF

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Publication number
WO2001038873A3
WO2001038873A3 PCT/US2000/029748 US0029748W WO0138873A3 WO 2001038873 A3 WO2001038873 A3 WO 2001038873A3 US 0029748 W US0029748 W US 0029748W WO 0138873 A3 WO0138873 A3 WO 0138873A3
Authority
WO
WIPO (PCT)
Prior art keywords
electrosensor
devices
methods
capture reagent
detecting analytes
Prior art date
Application number
PCT/US2000/029748
Other languages
French (fr)
Other versions
WO2001038873A2 (en
Inventor
Honghua Zhang
Original Assignee
Biotronic Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotronic Technologies Inc filed Critical Biotronic Technologies Inc
Priority to AU12419/01A priority Critical patent/AU1241901A/en
Publication of WO2001038873A2 publication Critical patent/WO2001038873A2/en
Publication of WO2001038873A3 publication Critical patent/WO2001038873A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/97—Test strip or test slide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Abstract

The present invention relates to devices comprising electrosensors containing capture reagents, their preparation thereof, and their use for detecting preferably, quantitative measurement, of analyte in a liquid sample. In particular, the invention relates to an enzyme electrosensor, e.g., electroimmunosensor, device for electrochemical detection and preferably, real-time measurement, which is suitable for use at point-of-care settings by unskilled personnel.
PCT/US2000/029748 1999-11-24 2000-10-27 Devices and methods for detecting analytes using electrosensor having capture reagent WO2001038873A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU12419/01A AU1241901A (en) 1999-11-24 2000-10-27 Devices and methods for detecting analytes using electrosensor having capture reagent

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16740999P 1999-11-24 1999-11-24
US60/167,409 1999-11-24

Publications (2)

Publication Number Publication Date
WO2001038873A2 WO2001038873A2 (en) 2001-05-31
WO2001038873A3 true WO2001038873A3 (en) 2002-07-11

Family

ID=22607271

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/029748 WO2001038873A2 (en) 1999-11-24 2000-10-27 Devices and methods for detecting analytes using electrosensor having capture reagent

Country Status (4)

Country Link
US (2) US6670115B1 (en)
AU (1) AU1241901A (en)
TW (1) TWI224673B (en)
WO (1) WO2001038873A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9399787B2 (en) 2002-12-20 2016-07-26 Acea Biosciences, Inc. Real-time electronic cell sensing system and applications for cytotoxicity profiling and compound assays

Families Citing this family (203)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8527026B2 (en) 1997-03-04 2013-09-03 Dexcom, Inc. Device and method for determining analyte levels
US6001067A (en) 1997-03-04 1999-12-14 Shults; Mark C. Device and method for determining analyte levels
US6036924A (en) 1997-12-04 2000-03-14 Hewlett-Packard Company Cassette of lancet cartridges for sampling blood
US20020144905A1 (en) * 1997-12-17 2002-10-10 Christian Schmidt Sample positioning and analysis system
DE59801410D1 (en) * 1997-12-17 2001-10-11 Ecole Polytech POSITIONING AND ELECTROPHYSIOLOGICAL CHARACTERIZATION OF INDIVIDUAL CELLS AND RECONSTRUCTED MEMBRANE SYSTEMS ON MICROSTRUCTURED CARRIERS
US6391005B1 (en) 1998-03-30 2002-05-21 Agilent Technologies, Inc. Apparatus and method for penetration with shaft having a sensor for sensing penetration depth
US7270730B2 (en) * 2000-08-04 2007-09-18 Essen Instruments, Inc. High-throughput electrophysiological measurement system
US8641644B2 (en) 2000-11-21 2014-02-04 Sanofi-Aventis Deutschland Gmbh Blood testing apparatus having a rotatable cartridge with multiple lancing elements and testing means
DE60234598D1 (en) 2001-06-12 2010-01-14 Pelikan Technologies Inc SELF-OPTIMIZING LANZET DEVICE WITH ADAPTANT FOR TEMPORAL FLUCTUATIONS OF SKIN PROPERTIES
US8337419B2 (en) 2002-04-19 2012-12-25 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9795747B2 (en) 2010-06-02 2017-10-24 Sanofi-Aventis Deutschland Gmbh Methods and apparatus for lancet actuation
US7749174B2 (en) 2001-06-12 2010-07-06 Pelikan Technologies, Inc. Method and apparatus for lancet launching device intergrated onto a blood-sampling cartridge
EP1404234B1 (en) 2001-06-12 2011-02-09 Pelikan Technologies Inc. Apparatus for improving success rate of blood yield from a fingerstick
US7025774B2 (en) 2001-06-12 2006-04-11 Pelikan Technologies, Inc. Tissue penetration device
US7682318B2 (en) 2001-06-12 2010-03-23 Pelikan Technologies, Inc. Blood sampling apparatus and method
US7981056B2 (en) 2002-04-19 2011-07-19 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US9427532B2 (en) 2001-06-12 2016-08-30 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
US9226699B2 (en) 2002-04-19 2016-01-05 Sanofi-Aventis Deutschland Gmbh Body fluid sampling module with a continuous compression tissue interface surface
ATE485766T1 (en) 2001-06-12 2010-11-15 Pelikan Technologies Inc ELECTRICAL ACTUATING ELEMENT FOR A LANCET
US20030032874A1 (en) 2001-07-27 2003-02-13 Dexcom, Inc. Sensor head for use with implantable devices
JP4383860B2 (en) * 2001-08-09 2009-12-16 パナソニック株式会社 Biosensor and measurement method
US7767437B2 (en) * 2001-11-02 2010-08-03 Genefluidics, Inc. System for detection of a component in a liquid
US8367013B2 (en) 2001-12-24 2013-02-05 Kimberly-Clark Worldwide, Inc. Reading device, method, and system for conducting lateral flow assays
US20030119203A1 (en) 2001-12-24 2003-06-26 Kimberly-Clark Worldwide, Inc. Lateral flow assay devices and methods for conducting assays
US8364229B2 (en) 2003-07-25 2013-01-29 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US7613491B2 (en) 2002-05-22 2009-11-03 Dexcom, Inc. Silicone based membranes for use in implantable glucose sensors
US7828728B2 (en) * 2003-07-25 2010-11-09 Dexcom, Inc. Analyte sensor
US7419821B2 (en) * 2002-03-05 2008-09-02 I-Stat Corporation Apparatus and methods for analyte measurement and immunoassay
AR039102A1 (en) * 2002-03-26 2005-02-09 Lai Derhsing INTEGRATED CIRCUIT CHIP FOR BIOLOGICAL TESTS
US7892185B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US8702624B2 (en) 2006-09-29 2014-04-22 Sanofi-Aventis Deutschland Gmbh Analyte measurement device with a single shot actuator
US7229458B2 (en) 2002-04-19 2007-06-12 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7232451B2 (en) 2002-04-19 2007-06-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7892183B2 (en) 2002-04-19 2011-02-22 Pelikan Technologies, Inc. Method and apparatus for body fluid sampling and analyte sensing
US8267870B2 (en) 2002-04-19 2012-09-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for body fluid sampling with hybrid actuation
US7976476B2 (en) 2002-04-19 2011-07-12 Pelikan Technologies, Inc. Device and method for variable speed lancet
US7297122B2 (en) 2002-04-19 2007-11-20 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7717863B2 (en) 2002-04-19 2010-05-18 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8784335B2 (en) 2002-04-19 2014-07-22 Sanofi-Aventis Deutschland Gmbh Body fluid sampling device with a capacitive sensor
US8221334B2 (en) 2002-04-19 2012-07-17 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US9248267B2 (en) 2002-04-19 2016-02-02 Sanofi-Aventis Deustchland Gmbh Tissue penetration device
US7901362B2 (en) 2002-04-19 2011-03-08 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7674232B2 (en) 2002-04-19 2010-03-09 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7491178B2 (en) 2002-04-19 2009-02-17 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US8360992B2 (en) 2002-04-19 2013-01-29 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7371247B2 (en) 2002-04-19 2008-05-13 Pelikan Technologies, Inc Method and apparatus for penetrating tissue
US7648468B2 (en) 2002-04-19 2010-01-19 Pelikon Technologies, Inc. Method and apparatus for penetrating tissue
US7331931B2 (en) 2002-04-19 2008-02-19 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7175642B2 (en) 2002-04-19 2007-02-13 Pelikan Technologies, Inc. Methods and apparatus for lancet actuation
US8579831B2 (en) 2002-04-19 2013-11-12 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7226461B2 (en) 2002-04-19 2007-06-05 Pelikan Technologies, Inc. Method and apparatus for a multi-use body fluid sampling device with sterility barrier release
US7291117B2 (en) 2002-04-19 2007-11-06 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US7547287B2 (en) 2002-04-19 2009-06-16 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9795334B2 (en) 2002-04-19 2017-10-24 Sanofi-Aventis Deutschland Gmbh Method and apparatus for penetrating tissue
US7909778B2 (en) * 2002-04-19 2011-03-22 Pelikan Technologies, Inc. Method and apparatus for penetrating tissue
US9314194B2 (en) 2002-04-19 2016-04-19 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
AT500427B1 (en) * 2002-05-29 2009-02-15 Anagnostics Bioanalysis Gmbh DEVICE FOR ANALYZING INGREDIENTS OF A SAMPLE
GB2391068A (en) * 2002-07-18 2004-01-28 Sensor Tech Ltd A lateral flow through device comprising an electrochemical sesor
US7470533B2 (en) 2002-12-20 2008-12-30 Acea Biosciences Impedance based devices and methods for use in assays
US7732127B2 (en) 2002-12-20 2010-06-08 Acea Biosciences, Inc. Dynamic monitoring of cell adhesion and spreading using the RT-CES system
CA2493108C (en) * 2002-07-20 2011-08-30 Xiaobo Wang Impedance based devices and methods for use in assays
US7468255B2 (en) 2002-12-20 2008-12-23 Acea Biosciences Method for assaying for natural killer, cytotoxic T-lymphocyte and neutrophil-mediated killing of target cells using real-time microelectronic cell sensing technology
US8263375B2 (en) 2002-12-20 2012-09-11 Acea Biosciences Dynamic monitoring of activation of G-protein coupled receptor (GPCR) and receptor tyrosine kinase (RTK) in living cells using real-time microelectronic cell sensing technology
US7192752B2 (en) 2002-12-20 2007-03-20 Acea Biosciences Real time electronic cell sensing systems and applications for cell-based assays
US8206903B2 (en) 2002-12-20 2012-06-26 Acea Biosciences Device and method for electroporation-based delivery of molecules into cells and dynamic monitoring of cell responses
US7285424B2 (en) 2002-08-27 2007-10-23 Kimberly-Clark Worldwide, Inc. Membrane-based assay devices
US7781172B2 (en) 2003-11-21 2010-08-24 Kimberly-Clark Worldwide, Inc. Method for extending the dynamic detection range of assay devices
US7247500B2 (en) 2002-12-19 2007-07-24 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in membrane-based assay devices
US11346797B2 (en) 2002-12-20 2022-05-31 Agilent Technologies, Inc. System and method for monitoring cardiomyocyte beating, viability, morphology and electrophysiological properties
US10551371B2 (en) 2003-11-10 2020-02-04 Acea Biosciences, Inc. System and method for monitoring cardiomyocyte beating, viability and morphology and for screening for pharmacological agents which may induce cardiotoxicity or modulate cardiomyocyte function
US10215748B2 (en) 2002-12-20 2019-02-26 Acea Biosciences, Inc. Using impedance-based cell response profiling to identify putative inhibitors for oncogene addicted targets or pathways
US10539523B2 (en) 2002-12-20 2020-01-21 Acea Biosciences, Inc. System and method for monitoring cardiomyocyte beating, viability, morphology, and electrophysiological properties
US8574895B2 (en) 2002-12-30 2013-11-05 Sanofi-Aventis Deutschland Gmbh Method and apparatus using optical techniques to measure analyte levels
US7851209B2 (en) 2003-04-03 2010-12-14 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in assay devices
US20040197819A1 (en) 2003-04-03 2004-10-07 Kimberly-Clark Worldwide, Inc. Assay devices that utilize hollow particles
EP1628567B1 (en) 2003-05-30 2010-08-04 Pelikan Technologies Inc. Method and apparatus for fluid injection
DK1633235T3 (en) 2003-06-06 2014-08-18 Sanofi Aventis Deutschland Apparatus for sampling body fluid and detecting analyte
WO2006001797A1 (en) 2004-06-14 2006-01-05 Pelikan Technologies, Inc. Low pain penetrating
JP4708342B2 (en) 2003-07-25 2011-06-22 デックスコム・インコーポレーテッド Oxygen augmentation membrane system for use in implantable devices
US9763609B2 (en) 2003-07-25 2017-09-19 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US7723099B2 (en) 2003-09-10 2010-05-25 Abbott Point Of Care Inc. Immunoassay device with immuno-reference electrode
JP2007506946A (en) * 2003-09-23 2007-03-22 エピネックス・ダイアグノスティクス・インコーポレーテッド Rapid examination of glycoalbumin
US8282576B2 (en) 2003-09-29 2012-10-09 Sanofi-Aventis Deutschland Gmbh Method and apparatus for an improved sample capture device
US7399400B2 (en) 2003-09-30 2008-07-15 Nano-Proprietary, Inc. Nanobiosensor and carbon nanotube thin film transistors
EP1680014A4 (en) 2003-10-14 2009-01-21 Pelikan Technologies Inc Method and apparatus for a variable user interface
US20080245664A1 (en) * 2003-11-12 2008-10-09 Yu-Hong Chang Biosensor test strips for multiple tests
US20050100880A1 (en) * 2003-11-12 2005-05-12 Yu-Hong Chang Biosensor test strips of multiple function for multiple uses
US7943395B2 (en) 2003-11-21 2011-05-17 Kimberly-Clark Worldwide, Inc. Extension of the dynamic detection range of assay devices
US20050112703A1 (en) 2003-11-21 2005-05-26 Kimberly-Clark Worldwide, Inc. Membrane-based lateral flow assay devices that utilize phosphorescent detection
US7713748B2 (en) 2003-11-21 2010-05-11 Kimberly-Clark Worldwide, Inc. Method of reducing the sensitivity of assay devices
US7476360B2 (en) 2003-12-09 2009-01-13 Genefluidics, Inc. Cartridge for use with electrochemical sensor
US20050136500A1 (en) * 2003-12-19 2005-06-23 Kimberly-Clark Worldwide; Inc. Flow-through assay devices
US7943089B2 (en) 2003-12-19 2011-05-17 Kimberly-Clark Worldwide, Inc. Laminated assay devices
US7822454B1 (en) 2005-01-03 2010-10-26 Pelikan Technologies, Inc. Fluid sampling device with improved analyte detecting member configuration
EP1706026B1 (en) 2003-12-31 2017-03-01 Sanofi-Aventis Deutschland GmbH Method and apparatus for improving fluidic flow and sample capture
DE102004005711A1 (en) * 2004-02-05 2006-05-11 Siemens Ag Biosensor for the determination of an allergen with operating procedures
US7781226B2 (en) * 2004-02-27 2010-08-24 The Board Of Regents Of The University Of Texas System Particle on membrane assay system
US8101431B2 (en) 2004-02-27 2012-01-24 Board Of Regents, The University Of Texas System Integration of fluids and reagents into self-contained cartridges containing sensor elements and reagent delivery systems
US20050191704A1 (en) * 2004-03-01 2005-09-01 Kimberly-Clark Worldwide, Inc. Assay devices utilizing chemichromic dyes
US8277713B2 (en) 2004-05-03 2012-10-02 Dexcom, Inc. Implantable analyte sensor
US8828203B2 (en) 2004-05-20 2014-09-09 Sanofi-Aventis Deutschland Gmbh Printable hydrogels for biosensors
EP1765194A4 (en) 2004-06-03 2010-09-29 Pelikan Technologies Inc Method and apparatus for a fluid sampling device
US9775553B2 (en) 2004-06-03 2017-10-03 Sanofi-Aventis Deutschland Gmbh Method and apparatus for a fluid sampling device
US7601299B2 (en) * 2004-06-18 2009-10-13 Roche Diagnostics Operations, Inc. System and method for coding information on a biosensor test strip
US7521226B2 (en) 2004-06-30 2009-04-21 Kimberly-Clark Worldwide, Inc. One-step enzymatic and amine detection technique
ATE369562T1 (en) * 2004-09-09 2007-08-15 Analyticon Biotechnologies Ag LATERAL FLOW MEASURING DEVICE AND MEASURING METHOD FOR ANALYTES
US20060063162A1 (en) * 2004-09-23 2006-03-23 Deng David X Biological marker for inflammation
US8652831B2 (en) 2004-12-30 2014-02-18 Sanofi-Aventis Deutschland Gmbh Method and apparatus for analyte measurement test time
US8744546B2 (en) 2005-05-05 2014-06-03 Dexcom, Inc. Cellulosic-based resistance domain for an analyte sensor
EP1910824A4 (en) 2005-05-31 2012-11-21 Labnow Inc Methods and compositions related to determination and use of white blood cell counts
EP2508867A1 (en) * 2005-06-24 2012-10-10 Board Of Regents, The University Of Texas System Systems and methods including self-contained cartridges with detection systems and fluid delivery systems
US20070015291A1 (en) * 2005-07-18 2007-01-18 Smith Henry J Rapid test for glycated albumin in blood
US8475715B2 (en) * 2005-08-12 2013-07-02 Bioscale, Inc. Resonant sensor systems and methods with reduced gas interference
AT502549B1 (en) * 2005-10-07 2007-06-15 Anagnostics Bioanalysis Gmbh DEVICE FOR THE ANALYSIS OF LIQUID SAMPLES
EP1965212B1 (en) * 2005-10-31 2012-01-18 National University Corporation Hokkaido University Non-liquid phase type chemiluminescent enzyme immunoassay method and assay kit
US8105244B2 (en) * 2005-11-30 2012-01-31 Abbott Diabetes Care Inc. Integrated sensor for analyzing biological samples
US8815175B2 (en) * 2005-11-30 2014-08-26 Abbott Diabetes Care Inc. Integrated meter for analyzing biological samples
US7922971B2 (en) * 2005-11-30 2011-04-12 Abbott Diabetes Care Inc. Integrated meter for analyzing biological samples
US20070202561A1 (en) * 2006-02-10 2007-08-30 Becton Dickinson And Company Electronic Detection Immunoassays that Utilize a Binder Support Medium
US20100021940A1 (en) * 2006-04-12 2010-01-28 Astrazeneca Ab Method for Determining the Activity of a Protease in a Sample
US20070281321A1 (en) * 2006-05-31 2007-12-06 Esa Biosciences, Inc. Biosensor for measurement of species in a body fluid
WO2008020813A1 (en) * 2006-08-16 2008-02-21 Agency For Science, Technology And Research Method of electrically detecting a biological analyte molecule
US8041515B2 (en) 2006-09-20 2011-10-18 Acea Biosciences, Inc. Use of impedance-based cytological profiling to classify cellular response profiles upon exposure to biologically active agents
US8431087B2 (en) * 2006-09-25 2013-04-30 Covidien Lp Carbon dioxide detector having borosilicate substrate
US8449834B2 (en) * 2006-09-25 2013-05-28 Covidien Lp Carbon dioxide detector having borosilicate substrate
US8420405B2 (en) 2006-09-25 2013-04-16 Covidien Lp Carbon dioxide detector having borosilicate substrate
US8431088B2 (en) * 2006-09-25 2013-04-30 Covidien Lp Carbon dioxide detector having borosilicate substrate
US20080305512A1 (en) * 2006-10-26 2008-12-11 Mattingly Phillip G Assay for cardiac troponin autoantibodies
US7776605B2 (en) * 2006-10-26 2010-08-17 Abbott Laboratories Assay for cardiac troponin autoantibodies
WO2008051762A2 (en) * 2006-10-26 2008-05-02 Abbott Laboratories Immunoassay of analytes in samples containing endogenous anti-analyte antibodies
CA2673314C (en) 2006-12-29 2014-03-11 Abbott Laboratories Non-denaturing lysis reagent for use with capture-in-solution immunoassay
US20080177166A1 (en) * 2007-01-18 2008-07-24 Provex Technologies, Llc Ultrasensitive amperometric saliva glucose sensor strip
US20200037874A1 (en) 2007-05-18 2020-02-06 Dexcom, Inc. Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise
US20090042237A1 (en) * 2007-08-06 2009-02-12 Henry John Smith Aptamer based point-of-care test for glycated albumin
WO2009021908A2 (en) * 2007-08-10 2009-02-19 Unilever Plc Disposable enzymatic sensor for liquid samples
WO2009097174A2 (en) * 2008-01-07 2009-08-06 Stc.Unm Electrochemical biosensor
USD612279S1 (en) 2008-01-18 2010-03-23 Lifescan Scotland Limited User interface in an analyte meter
IL197532A0 (en) 2008-03-21 2009-12-24 Lifescan Scotland Ltd Analyte testing method and system
USD615431S1 (en) 2008-03-21 2010-05-11 Lifescan Scotland Limited Analyte test meter
USD611853S1 (en) 2008-03-21 2010-03-16 Lifescan Scotland Limited Analyte test meter
USD612275S1 (en) 2008-03-21 2010-03-23 Lifescan Scotland, Ltd. Analyte test meter
US11730407B2 (en) 2008-03-28 2023-08-22 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US8682408B2 (en) 2008-03-28 2014-03-25 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US8583204B2 (en) 2008-03-28 2013-11-12 Dexcom, Inc. Polymer membranes for continuous analyte sensors
WO2009126900A1 (en) 2008-04-11 2009-10-15 Pelikan Technologies, Inc. Method and apparatus for analyte detecting device
EP2291645B1 (en) 2008-05-05 2015-09-09 Acea Biosciences, Inc. Label-free monitoring of excitation-contraction coupling and excitable cells using impedance based systems with millisecond time resolution
USD611151S1 (en) 2008-06-10 2010-03-02 Lifescan Scotland, Ltd. Test meter
USD611489S1 (en) 2008-07-25 2010-03-09 Lifescan, Inc. User interface display for a glucose meter
USD611372S1 (en) 2008-09-19 2010-03-09 Lifescan Scotland Limited Analyte test meter
EP2326944B1 (en) 2008-09-19 2020-08-19 Dexcom, Inc. Particle-containing membrane and particulate electrode for analyte sensors
EP2348316B1 (en) * 2008-10-09 2013-08-28 Actherm Inc. A method for testing a liquid
AU2008362975B2 (en) * 2008-10-17 2013-03-28 Actherm Inc. A fluid test strip and method thereof
US7964370B2 (en) * 2008-10-17 2011-06-21 Actherm Inc Analytical strip and detecting method using the same
US20100167306A1 (en) * 2008-12-26 2010-07-01 Henry John Smith Rapid test for glycated albumin in saliva
US9375169B2 (en) 2009-01-30 2016-06-28 Sanofi-Aventis Deutschland Gmbh Cam drive for managing disposable penetrating member actions with a single motor and motor and control system
CN102395884A (en) * 2009-03-23 2012-03-28 红电医学科技股份有限公司 Fluid test chip and method to make it
US9046518B2 (en) 2009-04-09 2015-06-02 Hitachi Chemical Company, Ltd. Detector and detection method
TWI497074B (en) * 2009-04-13 2015-08-21 Hitachi Chemical Co Ltd Detecting device and detecting method thereof
US9506919B2 (en) * 2009-04-13 2016-11-29 The Board Of Trustees Of The Leland Stanford Junior University Methods and devices for detecting the presence of an analyte in a sample
KR101058420B1 (en) 2009-10-08 2011-08-24 경원대학교 산학협력단 Electrochemical sensor for detecting toxic bacteria and method for detecting toxic bacteria using same
US8652788B2 (en) * 2009-12-02 2014-02-18 Abbott Laboratories Assay for diagnosis of cardiac myocyte damage
US8835120B2 (en) * 2009-12-02 2014-09-16 Abbott Laboratories Assay for cardiac troponin-T (cTnT)
US20110136141A1 (en) 2009-12-03 2011-06-09 Abbott Laboratories Peptide reagents and method for inhibiting autoantibody antigen binding
US8183002B2 (en) 2009-12-03 2012-05-22 Abbott Laboratories Autoantibody enhanced immunoassays and kits
IL209760A (en) 2009-12-11 2015-05-31 Lifescan Scotland Ltd Fill sufficiency method and system
EP2545367B1 (en) * 2010-03-12 2022-02-09 The Board of Trustees of the Leland Stanford Junior University Magnetic sensor based quantitative binding kinetics analysis
EP2550362B1 (en) 2010-03-25 2017-01-04 Oregon Health&Science University Cmv glycoproteins and recombinant vectors
US8965476B2 (en) 2010-04-16 2015-02-24 Sanofi-Aventis Deutschland Gmbh Tissue penetration device
WO2011146531A1 (en) 2010-05-18 2011-11-24 Acea Biosciences, Inc Data analysis of impedance-based cardiomyocyte-beating signals as detected on real-time cell analysis (rtca) cardio instruments
US9918656B2 (en) * 2010-06-25 2018-03-20 Massachusetts Institute Of Technology Implantable magnetic relaxation sensors and methods of measuring a sensor's cumulative exposure to a biomarker
US8512950B2 (en) 2010-07-21 2013-08-20 Saint Louis University Biolayer interferometry measurement of biological targets
WO2012116233A2 (en) * 2011-02-23 2012-08-30 Pure Imagination Llc Interactive play set with capacitive sensors
AU2012229156A1 (en) 2011-03-11 2013-10-31 Board Of Regents Of The University Of Nebraska Biomarker for coronary artery disease
WO2012151465A1 (en) * 2011-05-04 2012-11-08 Pop Test, Llc Diagnostic device
JP2012242366A (en) * 2011-05-24 2012-12-10 Sharp Corp Biosensor and analytic method using the same
EP2691530B1 (en) 2011-06-10 2018-03-07 Oregon Health & Science University Cmv glycoproteins and recombinant vectors
US20110241650A1 (en) * 2011-06-20 2011-10-06 Ying Zhang Electrochemical sensor for disinfectants
EP2568289A3 (en) 2011-09-12 2013-04-03 International AIDS Vaccine Initiative Immunoselection of recombinant vesicular stomatitis virus expressing hiv-1 proteins by broadly neutralizing antibodies
US9402894B2 (en) 2011-10-27 2016-08-02 International Aids Vaccine Initiative Viral particles derived from an enveloped virus
JP6019415B2 (en) * 2012-03-05 2016-11-02 パナソニックＩｐマネジメント株式会社 Sensor device
TWM441450U (en) * 2012-04-19 2012-11-21 Bioptik Tech Inc Filtering type test strip
EP2679596B1 (en) 2012-06-27 2017-04-12 International Aids Vaccine Initiative HIV-1 env glycoprotein variant
AU2013280268B2 (en) * 2012-06-28 2015-02-26 Siemens Healthcare Diagnostics Inc. Reader device and method of signal amplification
EP2811301B1 (en) * 2012-11-15 2017-05-10 Ortho-Clinical Diagnostics, Inc. Quality/process control of a lateral flow assay device based on flow monitoring
KR102435654B1 (en) * 2013-03-11 2022-08-25 큐 헬스 인코퍼레이티드 Systems and methods for detection and quantification of analytes
EP2796876A1 (en) * 2013-04-25 2014-10-29 Hasenkam ApS Strip for monitoring analyte concentrations
US20150065381A1 (en) 2013-09-05 2015-03-05 International Aids Vaccine Initiative Methods of identifying novel hiv-1 immunogens
US10058604B2 (en) 2013-10-07 2018-08-28 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
AU2015238448B2 (en) * 2014-03-24 2019-04-18 Dolby International Ab Method and device for applying Dynamic Range Compression to a Higher Order Ambisonics signal
USD745423S1 (en) 2014-05-12 2015-12-15 Cue Inc. Automated analyzer test cartridge and sample collection device for analyte detection
EP3069730A3 (en) 2015-03-20 2017-03-15 International Aids Vaccine Initiative Soluble hiv-1 envelope glycoprotein trimers
US9931394B2 (en) 2015-03-23 2018-04-03 International Aids Vaccine Initiative Soluble HIV-1 envelope glycoprotein trimers
JP6116080B1 (en) * 2016-04-26 2017-04-19 日本航空電子工業株式会社 Electrochemical measurement method, electrochemical measurement apparatus and transducer
US10012645B2 (en) * 2016-08-24 2018-07-03 The Florida International University Board Of Trustees Rapid zika virus detection using nano-enabled electrochemical sensing system
US10705081B2 (en) * 2016-09-04 2020-07-07 Sympano, Inc. Nano-field electrical sensor
JP6218199B1 (en) * 2016-10-06 2017-10-25 日本航空電子工業株式会社 Electrochemical measuring device and transducer
WO2018093680A1 (en) 2016-11-15 2018-05-24 University Of Virginia Patent Foundation Electrochemical device for identifying electroactive analyte and related methods thereof
KR101877365B1 (en) * 2017-02-16 2018-07-13 광주과학기술원 A kit based on the paper for collecting dust particles in air
CN110582569B (en) 2017-03-03 2024-04-02 安捷伦科技有限公司 Methods and systems for functional maturation of iPSC and ESC-derived cardiomyocytes
EP3821056B1 (en) * 2018-07-13 2024-03-13 Siemens Healthcare Diagnostics, Inc. Microalbumin creatinine assay detection flag and methods of production and use related thereto
AU2021237737A1 (en) * 2020-03-20 2022-11-24 Orbis Diagnostics Limited Multi-chambered assay devices and associated methods, systems and apparatuses thereof for detection of analytes
CN113702468A (en) * 2020-05-20 2021-11-26 无锡锦帛诚医疗器械科技有限公司 Chloride ion quantitative detection dry sheet for in vitro diagnosis
WO2022207693A1 (en) * 2021-03-31 2022-10-06 Dsm Ip Assets B.V. Sensor for measuring amounts of vitamin c and d

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0153875A2 (en) * 1984-03-01 1985-09-04 The State Of Victoria Enzyme-linked immunosorbent assay method and test kit
US5830680A (en) * 1994-04-26 1998-11-03 The Regents Of The University Of Michigan Unitary sandwhich enzyme immunoassay cassette device and method of use
WO1998052042A1 (en) * 1997-05-14 1998-11-19 Keensense, Inc. Molecular wire injection sensors

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5622871A (en) 1987-04-27 1997-04-22 Unilever Patent Holdings B.V. Capillary immunoassay and device therefor comprising mobilizable particulate labelled reagents
SE343949B (en) * 1966-06-02 1972-03-20 Pharmacia Ab
GB8402058D0 (en) 1984-01-26 1984-02-29 Serono Diagnostics Ltd Methods of assay
US4703017C1 (en) 1984-02-14 2001-12-04 Becton Dickinson Co Solid phase assay with visual readout
US5039607A (en) 1988-05-17 1991-08-13 Syntex (U.S.A.) Inc. Method for immunochromatographic analysis
US5215899A (en) 1989-11-09 1993-06-01 Miles Inc. Nucleic acid amplification employing ligatable hairpin probe and transcription
US5286362A (en) * 1990-02-03 1994-02-15 Boehringer Mannheim Gmbh Method and sensor electrode system for the electrochemical determination of an analyte or an oxidoreductase as well as the use of suitable compounds therefor
US5271895A (en) * 1991-02-27 1993-12-21 Boehringer Mannheim Corporation Test strip
US5726010A (en) * 1991-07-31 1998-03-10 Idexx Laboratories, Inc. Reversible flow chromatographic binding assay
US5391272A (en) 1992-03-06 1995-02-21 Andcare, Inc. Electrochemical immunoassay methods
GB9309797D0 (en) * 1993-05-12 1993-06-23 Medisense Inc Electrochemical sensors
US5413690A (en) * 1993-07-23 1995-05-09 Boehringer Mannheim Corporation Potentiometric biosensor and the method of its use
CA2170402C (en) * 1993-08-24 2000-07-18 Michael P. Allen Novel disposable electronic assay device
US5756362A (en) 1993-10-12 1998-05-26 Cornell Research Foundation, Inc. Liposome-enhanced immunoaggregation assay and test device
US5789154A (en) * 1993-10-12 1998-08-04 Cornell Research Foundation, Inc. Liposome-enhanced immunoassay and test device
EP0752099A1 (en) * 1994-02-09 1997-01-08 Abbott Laboratories Diagnostic flow cell device
US5762770A (en) * 1994-02-21 1998-06-09 Boehringer Mannheim Corporation Electrochemical biosensor test strip
GB9415499D0 (en) * 1994-08-01 1994-09-21 Bartlett Philip N Electrodes and their use in analysis
US5972199A (en) * 1995-10-11 1999-10-26 E. Heller & Company Electrochemical analyte sensors using thermostable peroxidase
US5753517A (en) 1996-03-29 1998-05-19 University Of British Columbia Quantitative immunochromatographic assays
DE19622458C2 (en) * 1996-05-24 1998-03-26 Senslab Ges Zur Entwicklung Un Enzymatic-electrochemical one-step affinity sensor for the quantitative determination of analytes in aqueous media and affinity assay
US5798273A (en) 1996-09-25 1998-08-25 Becton Dickinson And Company Direct read lateral flow assay for small analytes
US6358752B1 (en) * 1996-09-27 2002-03-19 Cornell Research Foundation, Inc. Liposome-enhanced test device and method
US5958791A (en) * 1996-09-27 1999-09-28 Innovative Biotechnologies, Inc. Interdigitated electrode arrays for liposome-enhanced immunoassay and test device
US6100045A (en) * 1997-02-10 2000-08-08 Dsm N.V. Detection of analytes using electrochemistry
US6391558B1 (en) 1997-03-18 2002-05-21 Andcare, Inc. Electrochemical detection of nucleic acid sequences
EP1010014B1 (en) 1997-05-13 2003-10-01 Vacuumschmelze GmbH Magnet core
JP4433100B2 (en) * 1997-06-20 2010-03-17 ニューヨーク ユニヴァーシティ Electrostatic spraying of substance solutions in mass production of chips and libraries
US6174734B1 (en) * 1997-10-24 2001-01-16 Abbott Laboratories Measurement of glycated hemoglobin
US6587705B1 (en) * 1998-03-13 2003-07-01 Lynn Kim Biosensor, iontophoretic sampling system, and methods of use thereof
RU2161653C2 (en) * 1998-08-24 2001-01-10 ФАРМАКОВСКИЙ Дмитрий Александрович Method of quantitative electrochemical analysis of biological molecules
DE19841803A1 (en) * 1998-09-12 2000-03-16 Bayer Ag Organic electroluminescent device, i.e. light-emitting diode, has hole-injecting layer of polymeric organic conductor formed by coating from solution or from sub-micron dispersion
US6338790B1 (en) * 1998-10-08 2002-01-15 Therasense, Inc. Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator
TW369411B (en) * 1998-11-09 1999-09-11 Apex Biotechnology Co Ltd Disposal electrode test block for current-type non-enzymatic uric acid test, its process and application
US6305214B1 (en) * 1999-08-26 2001-10-23 Sensor Tek, Llc Gas sensor and methods of forming a gas sensor assembly

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0153875A2 (en) * 1984-03-01 1985-09-04 The State Of Victoria Enzyme-linked immunosorbent assay method and test kit
US5830680A (en) * 1994-04-26 1998-11-03 The Regents Of The University Of Michigan Unitary sandwhich enzyme immunoassay cassette device and method of use
WO1998052042A1 (en) * 1997-05-14 1998-11-19 Keensense, Inc. Molecular wire injection sensors

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9399787B2 (en) 2002-12-20 2016-07-26 Acea Biosciences, Inc. Real-time electronic cell sensing system and applications for cytotoxicity profiling and compound assays

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US6670115B1 (en) 2003-12-30

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