WO2001040278A3 - Human semaphorin zsmf-16 - Google Patents

Human semaphorin zsmf-16 Download PDF

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Publication number
WO2001040278A3
WO2001040278A3 PCT/US2000/033116 US0033116W WO0140278A3 WO 2001040278 A3 WO2001040278 A3 WO 2001040278A3 US 0033116 W US0033116 W US 0033116W WO 0140278 A3 WO0140278 A3 WO 0140278A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptides
zsmf
methods
polynucleotides encoding
semaphorin
Prior art date
Application number
PCT/US2000/033116
Other languages
French (fr)
Other versions
WO2001040278A2 (en
Inventor
James L Holloway
Kevin P Foley
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Priority to AU20655/01A priority Critical patent/AU2065501A/en
Publication of WO2001040278A2 publication Critical patent/WO2001040278A2/en
Publication of WO2001040278A3 publication Critical patent/WO2001040278A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease

Abstract

Semaphorin polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed. The polypeptide is expressed in breast cancer, and neuronal tissues. The polypeptides, and polynucleotides encoding them, may be used for detecting human chromosomal abnormalities and cancers. The polypeptides may be used within methods for detecting receptors that mediate neurite outgrowth, modulate cellular proliferation and/or differentiation, and immune response. The present invention also includes antibodies to the ZSMF-16 polypeptides and uses therefor.
PCT/US2000/033116 1999-12-06 2000-12-06 Human semaphorin zsmf-16 WO2001040278A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU20655/01A AU2065501A (en) 1999-12-06 2000-12-06 Human semaphorin zsmf-16

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45556099A 1999-12-06 1999-12-06
US09/455,560 1999-12-06

Publications (2)

Publication Number Publication Date
WO2001040278A2 WO2001040278A2 (en) 2001-06-07
WO2001040278A3 true WO2001040278A3 (en) 2001-11-29

Family

ID=23809325

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/033116 WO2001040278A2 (en) 1999-12-06 2000-12-06 Human semaphorin zsmf-16

Country Status (2)

Country Link
AU (1) AU2065501A (en)
WO (1) WO2001040278A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3582797A1 (en) * 2017-02-14 2019-12-25 Yissum Research Development Company of The Hebrew University of Jerusalem Ltd. Naf-1 derived peptides and uses thereof

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5416197A (en) * 1993-10-15 1995-05-16 Trustees Of The University Of Pennsylvania Antibodies which bind human collapsin
WO1999032622A2 (en) * 1997-12-19 1999-07-01 Zymogenetics, Inc. Semaphorin zsmf-3
WO1999045114A2 (en) * 1998-03-03 1999-09-10 Zymogenetics, Inc. Human semaphorin zsmf-7
WO1999047671A2 (en) * 1998-03-13 1999-09-23 Lukanidin Eugene M Dna sequences encoding semaphorin-h and diagnosis of metastatic cancer
US5981222A (en) * 1996-08-23 1999-11-09 Genetics Institute, Inc. Human semaphorin E, secreted proteins and polynucleotides encoding them
EP0960937A1 (en) * 1996-09-11 1999-12-01 Sumitomo Pharmaceuticals Company, Limited Novel semaphorin gene: semaphorin y

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5416197A (en) * 1993-10-15 1995-05-16 Trustees Of The University Of Pennsylvania Antibodies which bind human collapsin
US5981222A (en) * 1996-08-23 1999-11-09 Genetics Institute, Inc. Human semaphorin E, secreted proteins and polynucleotides encoding them
EP0960937A1 (en) * 1996-09-11 1999-12-01 Sumitomo Pharmaceuticals Company, Limited Novel semaphorin gene: semaphorin y
WO1999032622A2 (en) * 1997-12-19 1999-07-01 Zymogenetics, Inc. Semaphorin zsmf-3
WO1999045114A2 (en) * 1998-03-03 1999-09-10 Zymogenetics, Inc. Human semaphorin zsmf-7
WO1999047671A2 (en) * 1998-03-13 1999-09-23 Lukanidin Eugene M Dna sequences encoding semaphorin-h and diagnosis of metastatic cancer

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE GENESEQ [online] XP002167127, retrieved from GENESEQ Database accession no. r74175 *
HALL ET AL: "Human CD100, a novel leukocyte semaphorin that promotes B-cell aggregation and differentiation", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA,US,NATIONAL ACADEMY OF SCIENCE. WASHINGTON, vol. 93, October 1996 (1996-10-01), pages 11780 - 11785, XP002134057, ISSN: 0027-8424 *
KOLODKIN ET AL: "Semaphorins: Mediators of repulsive growth cone guidance", TRENDS IN CELL BIOLOGY,XX,ELSEVIER SCIENCE LTD, vol. 6, no. 1, 1996, pages 15 - 22, XP002084499, ISSN: 0962-8924 *
YAMADA ET AL.: "Identification of semaphorin E as a non-MDR drug resistance gene of human cancers", PROC. NATL. ACAD. SCI. USA, vol. 94, December 1997 (1997-12-01), pages 14713 - 14718, XP002076549 *

Also Published As

Publication number Publication date
WO2001040278A2 (en) 2001-06-07
AU2065501A (en) 2001-06-12

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