WO2001044284A3 - Chimeric natriuretic peptides - Google Patents
Chimeric natriuretic peptides Download PDFInfo
- Publication number
- WO2001044284A3 WO2001044284A3 PCT/US2000/034080 US0034080W WO0144284A3 WO 2001044284 A3 WO2001044284 A3 WO 2001044284A3 US 0034080 W US0034080 W US 0034080W WO 0144284 A3 WO0144284 A3 WO 0144284A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- natriuretic peptides
- chimeric natriuretic
- peptides
- chimeric
- natriuretics
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/58—Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Abstract
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU24339/01A AU2433901A (en) | 1999-12-17 | 2000-12-15 | Chimeric natriuretic peptides |
EP00988092A EP1242452B1 (en) | 1999-12-17 | 2000-12-15 | Chimeric natriuretic peptides |
CA2395585A CA2395585C (en) | 1999-12-17 | 2000-12-15 | Chimeric natriuretic peptides |
DE60033431T DE60033431T2 (en) | 1999-12-17 | 2000-12-15 | CHIMERIC NATRIURETIC PEPTIDES |
DK00988092T DK1242452T3 (en) | 1999-12-17 | 2000-12-15 | Chimeric natriuretic peptides |
JP2001544773A JP5031964B2 (en) | 1999-12-17 | 2000-12-15 | Chimeric natriuretic peptide |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/466,268 | 1999-12-17 | ||
US09/466,268 US6407211B1 (en) | 1999-12-17 | 1999-12-17 | Chimeric natriuretic peptides |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2001044284A2 WO2001044284A2 (en) | 2001-06-21 |
WO2001044284A3 true WO2001044284A3 (en) | 2002-01-31 |
Family
ID=23851133
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2000/034080 WO2001044284A2 (en) | 1999-12-17 | 2000-12-15 | Chimeric natriuretic peptides |
Country Status (11)
Country | Link |
---|---|
US (4) | US6407211B1 (en) |
EP (1) | EP1242452B1 (en) |
JP (1) | JP5031964B2 (en) |
AT (1) | ATE353916T1 (en) |
AU (1) | AU2433901A (en) |
CA (1) | CA2395585C (en) |
DE (1) | DE60033431T2 (en) |
DK (1) | DK1242452T3 (en) |
ES (1) | ES2282160T3 (en) |
PT (1) | PT1242452E (en) |
WO (1) | WO2001044284A2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9102707B2 (en) | 2011-08-30 | 2015-08-11 | Mayo Foundation For Medical Education And Research | Natriuretic polypeptides |
Families Citing this family (84)
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AU5043900A (en) * | 1999-05-24 | 2000-12-12 | Mayo Foundation For Medical Education And Research | Adenovirus vectors encoding brain natriuretic peptide |
US6407211B1 (en) * | 1999-12-17 | 2002-06-18 | Mayo Foundation For Medical Education And Research | Chimeric natriuretic peptides |
US20050113286A1 (en) * | 2002-03-18 | 2005-05-26 | Schreiner George F. | Methods for treating congestive heart failure |
US20040063630A1 (en) * | 2002-03-18 | 2004-04-01 | Scios, Inc. | Treatment of congestive heart failure with natriuretic peptide and a diuretic |
AU2003270427A1 (en) * | 2002-09-06 | 2004-03-29 | University Of South Florida | Cellular delivery of natriuretic peptides |
US20080214437A1 (en) * | 2002-09-06 | 2008-09-04 | Mohapatra Shyam S | Methods and compositions for reducing activity of the atrial natriuretic peptide receptor and for treatment of diseases |
US7655772B2 (en) | 2002-09-06 | 2010-02-02 | University Of South Florida | Materials and methods for treatment of allergic diseases |
SG159387A1 (en) | 2002-11-26 | 2010-03-30 | Biocon Ltd In | Modified natriuretic compounds, conjugates, and uses thereof |
WO2004097368A2 (en) * | 2003-04-28 | 2004-11-11 | Ciphergen Biosystems, Inc. | Improved immunoassays |
EP2308889B1 (en) | 2003-06-20 | 2018-05-23 | Mayo Foundation For Medical Education And Research | Isoforms of brain natriuretic peptide |
GB2403533A (en) | 2003-06-30 | 2005-01-05 | Orion Corp | Atrial natriuretic peptide and brain natriuretic peptide and assays and uses thereof |
US7445933B2 (en) * | 2003-07-16 | 2008-11-04 | Abbott Laboratories, Inc. | Stable calibrators or controls for measuring human natriuretic peptides |
US7291501B2 (en) * | 2003-07-16 | 2007-11-06 | Abbott Laboratories | Stable compositions for measuring human natriuretic peptides |
US8076288B2 (en) | 2004-02-11 | 2011-12-13 | Amylin Pharmaceuticals, Inc. | Hybrid polypeptides having glucose lowering activity |
AU2005227870A1 (en) * | 2004-02-17 | 2005-10-13 | University Of South Florida | Materials and methods for treatment of inflammatory and cell proliferation disorders |
PT1759001E (en) | 2004-04-21 | 2011-07-12 | Enobia Pharma Inc | Bone delivery conjugates and method of using same to target proteins to bone |
DE602005026014D1 (en) * | 2004-07-15 | 2011-03-03 | Univ Queensland | PROTEIN-type compounds and applications thereof |
AT500800B1 (en) * | 2004-09-08 | 2008-07-15 | Biomedica Medizinprodukte Gmbh | PROCESS FOR DETERMINING PROBNP |
WO2006076471A2 (en) * | 2005-01-12 | 2006-07-20 | Nobex Corporation | Bnp conjugates and methods of use |
CA2597649A1 (en) | 2005-02-11 | 2006-08-17 | Amylin Pharmaceuticals, Inc. | Gip analog and hybrid polypeptides with selectable properties |
US8263545B2 (en) | 2005-02-11 | 2012-09-11 | Amylin Pharmaceuticals, Inc. | GIP analog and hybrid polypeptides with selectable properties |
SI2510942T1 (en) | 2005-04-07 | 2016-01-29 | Cardiorentis Ag | Use of natriuretic peptide for treating heart failure |
EP1922336B1 (en) * | 2005-08-11 | 2012-11-21 | Amylin Pharmaceuticals, LLC | Hybrid polypeptides with selectable properties |
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JP2009532385A (en) * | 2006-03-30 | 2009-09-10 | パラティン・テクノロジーズ・インコーポレーテッド | Linear natriuretic peptide construct |
CA2647143A1 (en) * | 2006-03-30 | 2007-10-11 | Palatin Technologies, Inc. | Cyclic natriuretic peptide constructs |
US8580746B2 (en) * | 2006-03-30 | 2013-11-12 | Palatin Technologies, Inc. | Amide linkage cyclic natriuretic peptide constructs |
CA2656990A1 (en) * | 2006-04-28 | 2007-11-08 | University Of South Florida | Materials and methods for reducing inflammation by inhibition of the atrial natriuretic peptide receptor |
BRPI0716416A2 (en) * | 2006-08-08 | 2016-10-11 | Mayo Foundation | substantially pure polypeptide between 37 and 47 amino acid in length, isolated nucleic acid, vector: host cell and pharmaceutical composition |
US8497240B2 (en) | 2006-08-17 | 2013-07-30 | Amylin Pharmaceuticals, Llc | DPP-IV resistant GIP hybrid polypeptides with selectable properties |
CN101600731A (en) * | 2006-09-08 | 2009-12-09 | 梅约医学教育与研究基金会 | The decorporation water and the natriuretic polypeptides that do not possess vasodilator activity |
US20100062984A1 (en) * | 2007-01-25 | 2010-03-11 | Rajiv Kumar | Fgf-23 polypeptides |
PT2765139T (en) * | 2007-07-20 | 2017-07-14 | Mayo Foundation | Natriuretic polypeptides |
US8357656B2 (en) | 2007-09-15 | 2013-01-22 | Mayo Foundation For Medical Education And Research | Natriuretic peptide receptor-C agonists |
WO2009055644A2 (en) * | 2007-10-24 | 2009-04-30 | California Institute Of Technology | Methods using the grueneberg ganglion chemosensory system |
EP2217620A2 (en) * | 2007-11-21 | 2010-08-18 | BioMarin Pharmaceutical Inc. | Variants of c-type natriuretic peptide |
WO2009086126A2 (en) * | 2007-12-21 | 2009-07-09 | Mayo Foundation For Medical Education And Research | Natriuretic polypeptides |
US9482677B2 (en) | 2008-02-27 | 2016-11-01 | Scios Inc. | Method, composition and device for sampling natriuretic peptides in a biological fluid |
CN102143757A (en) * | 2008-06-06 | 2011-08-03 | 梅约医学教育与研究基金会 | Chimeric natriuretic polypeptides and methods for inhibiting cardiac remodeling |
EP2334335A1 (en) * | 2008-09-19 | 2011-06-22 | Nektar Therapeutics | Polymer conjugates of cd-np peptides |
US8680263B2 (en) * | 2008-09-19 | 2014-03-25 | Nektar Therapeutics | Carbohydrate-based drug delivery polymers and conjugates thereof |
US8642550B2 (en) * | 2008-10-24 | 2014-02-04 | Mayo Foundation For Medical Education And Research | Chimeric natriuretic peptides without hypotensive inducing capability |
WO2010078325A2 (en) * | 2008-12-29 | 2010-07-08 | Mayo Foundation For Medical Education And Research | Natriuretic polypeptides for reducing or preventing restenosis |
US20120053123A1 (en) * | 2009-05-05 | 2012-03-01 | Mayo Foundation For Medical Education And Research | Natriuretic polypeptides having mutations within their disulfide rings |
PT2432489T (en) * | 2009-05-20 | 2016-12-07 | Biomarin Pharm Inc | Variants of c-type natriuretic peptide |
US20120108514A1 (en) | 2009-07-09 | 2012-05-03 | University Of Iowa Research Foundation | Long acting atrial natriuretic peptide (la-anp) and methods for use thereof |
ES2456502T3 (en) * | 2009-07-23 | 2014-04-22 | Igisu Co., Ltd. | Composition comprising PNC or GNP for an external skin preparation for the treatment of dermatitis |
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WO2012013597A1 (en) | 2010-07-28 | 2012-02-02 | Justus-Liebig-Universität Giessen | Substances and the use thereof for influencing natriuretic peptide receptors |
DE102010032482A1 (en) | 2010-07-28 | 2012-02-02 | Justus-Liebig-Universität Giessen | New receptor agonist having renin-suppressing activity, antihypertrophic activity and influence of second messenger cyclic guanosine monophosphate during vasodilation, natriuresis and diuresis, useful to treat e.g. nephrotic syndrome |
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US9314507B2 (en) | 2010-10-29 | 2016-04-19 | Capricor Therapeutics, Inc. | Methods of treatment of heart failure with natriuretic peptides |
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US10184942B2 (en) | 2011-03-17 | 2019-01-22 | University Of South Florida | Natriuretic peptide receptor as a biomarker for diagnosis and prognosis of cancer |
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JP2019528067A (en) * | 2016-08-18 | 2019-10-10 | ナショナル ユニヴァーシティー オブ シンガポール | Peptide having vasodilatory action and / or diuretic action |
US11224637B2 (en) | 2017-03-31 | 2022-01-18 | Alexion Pharmaceuticals, Inc. | Methods for treating hypophosphatasia (HPP) in adults and adolescents |
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WO1999012576A2 (en) * | 1997-09-11 | 1999-03-18 | Musc Foundation For Research Development | Methods and compositions for treating cardiac and renal disorders with atrial natriuretic peptide and tissue kallikrein gene therapy |
WO2000071576A2 (en) * | 1999-05-24 | 2000-11-30 | Mayo Foundation For Medical Education And Research | Adenovirus vectors encoding brain natriuretic peptide |
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-
1999
- 1999-12-17 US US09/466,268 patent/US6407211B1/en not_active Expired - Lifetime
-
2000
- 2000-12-15 ES ES00988092T patent/ES2282160T3/en not_active Expired - Lifetime
- 2000-12-15 EP EP00988092A patent/EP1242452B1/en not_active Expired - Lifetime
- 2000-12-15 AU AU24339/01A patent/AU2433901A/en not_active Abandoned
- 2000-12-15 DK DK00988092T patent/DK1242452T3/en active
- 2000-12-15 CA CA2395585A patent/CA2395585C/en not_active Expired - Fee Related
- 2000-12-15 AT AT00988092T patent/ATE353916T1/en active
- 2000-12-15 JP JP2001544773A patent/JP5031964B2/en not_active Expired - Fee Related
- 2000-12-15 PT PT00988092T patent/PT1242452E/en unknown
- 2000-12-15 WO PCT/US2000/034080 patent/WO2001044284A2/en active IP Right Grant
- 2000-12-15 DE DE60033431T patent/DE60033431T2/en not_active Expired - Lifetime
-
2002
- 2002-03-26 US US10/106,806 patent/US6818619B2/en not_active Expired - Lifetime
-
2004
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-
2008
- 2008-05-15 US US12/120,842 patent/US7964564B2/en not_active Expired - Fee Related
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9102707B2 (en) | 2011-08-30 | 2015-08-11 | Mayo Foundation For Medical Education And Research | Natriuretic polypeptides |
US9441027B2 (en) | 2011-08-30 | 2016-09-13 | Mayo Foundation For Medical Education And Research | Natriuretic polypeptides |
US9587004B2 (en) | 2011-08-30 | 2017-03-07 | Mayo Foundation For Medical Education And Research | Natriuretic polypeptides |
Also Published As
Publication number | Publication date |
---|---|
US7964564B2 (en) | 2011-06-21 |
PT1242452E (en) | 2007-05-31 |
AU2433901A (en) | 2001-06-25 |
US20050059600A1 (en) | 2005-03-17 |
US6407211B1 (en) | 2002-06-18 |
JP2003517005A (en) | 2003-05-20 |
WO2001044284A2 (en) | 2001-06-21 |
JP5031964B2 (en) | 2012-09-26 |
US20090170756A1 (en) | 2009-07-02 |
EP1242452B1 (en) | 2007-02-14 |
DK1242452T3 (en) | 2007-06-11 |
ATE353916T1 (en) | 2007-03-15 |
US20020082219A1 (en) | 2002-06-27 |
US20030069186A1 (en) | 2003-04-10 |
ES2282160T3 (en) | 2007-10-16 |
DE60033431D1 (en) | 2007-03-29 |
CA2395585A1 (en) | 2001-06-21 |
US7384917B2 (en) | 2008-06-10 |
US6818619B2 (en) | 2004-11-16 |
CA2395585C (en) | 2014-09-09 |
EP1242452A2 (en) | 2002-09-25 |
DE60033431T2 (en) | 2007-11-29 |
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