WO2001050983A1 - Implantable device - Google Patents
Implantable device Download PDFInfo
- Publication number
- WO2001050983A1 WO2001050983A1 PCT/IL2001/000031 IL0100031W WO0150983A1 WO 2001050983 A1 WO2001050983 A1 WO 2001050983A1 IL 0100031 W IL0100031 W IL 0100031W WO 0150983 A1 WO0150983 A1 WO 0150983A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- cells
- substance
- chamber
- oxygen
- functional
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/022—Artificial gland structures using bioreactors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14276—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body specially adapted for implantation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M2005/14204—Pressure infusion, e.g. using pumps with gas-producing electrochemical cell
Landscapes
- Health & Medical Sciences (AREA)
- Transplantation (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Cardiology (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Electrotherapy Devices (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- External Artificial Organs (AREA)
- Seal Device For Vehicle (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Description
Claims
Priority Applications (13)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AT01900607T ATE296589T1 (en) | 2000-01-12 | 2001-01-12 | IMPLANTABLE DEVICE CONTAINING LIVING CELLS |
ES01900607T ES2239662T3 (en) | 2000-01-12 | 2001-01-12 | IMPLANTABLE DEVICE CONTAINING LIVE CELLS. |
EP01900607A EP1351623B1 (en) | 2000-01-12 | 2001-01-12 | Implantable device containing living cells |
DK01900607T DK1351623T3 (en) | 2000-01-12 | 2001-01-12 | Implantable device containing living cells |
DK05011703T DK1645243T3 (en) | 2000-01-12 | 2001-01-12 | Implantable device |
AT05011703T ATE380526T1 (en) | 2000-01-12 | 2001-01-12 | IMPLANTABLE DEVICE |
US10/466,069 US7892222B2 (en) | 2000-01-12 | 2001-01-12 | Implantable device |
EP05011703A EP1645243B1 (en) | 2000-01-12 | 2001-01-12 | Implantable device |
AU25442/01A AU2544201A (en) | 2000-01-12 | 2001-01-12 | Implantable device |
DE60131913T DE60131913T2 (en) | 2000-01-12 | 2001-01-12 | Implantable device |
DE60111267T DE60111267T2 (en) | 2000-01-12 | 2001-01-12 | IMPLANTABLE DEVICE CONTAINING LIVING CELLS |
US11/001,556 US8012500B2 (en) | 2000-01-01 | 2004-11-30 | Implantable device |
US12/064,946 US8444630B2 (en) | 2000-01-12 | 2007-11-28 | Oxygen supply for cell transplant and vascularization |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL134009 | 2000-01-01 | ||
IL134009A IL134009A (en) | 2000-01-12 | 2000-01-12 | Implantable device |
Related Child Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10466069 A-371-Of-International | 2001-01-12 | ||
US11/001,556 Continuation-In-Part US8012500B2 (en) | 2000-01-01 | 2004-11-30 | Implantable device |
US12/064,946 Continuation-In-Part US8444630B2 (en) | 2000-01-12 | 2007-11-28 | Oxygen supply for cell transplant and vascularization |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2001050983A1 true WO2001050983A1 (en) | 2001-07-19 |
Family
ID=11073701
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IL2001/000031 WO2001050983A1 (en) | 2000-01-01 | 2001-01-12 | Implantable device |
Country Status (9)
Country | Link |
---|---|
US (1) | US7892222B2 (en) |
EP (2) | EP1351623B1 (en) |
AT (2) | ATE380526T1 (en) |
AU (1) | AU2544201A (en) |
DE (2) | DE60111267T2 (en) |
DK (2) | DK1351623T3 (en) |
ES (2) | ES2239662T3 (en) |
IL (1) | IL134009A (en) |
WO (1) | WO2001050983A1 (en) |
Cited By (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2003190259A (en) * | 2001-12-28 | 2003-07-08 | Hisako Ogawara | Chamber for artificial organ |
WO2006006166A2 (en) | 2004-07-14 | 2006-01-19 | Glusense, Ltd. | Implantable power sources and sensors |
EP1827490A2 (en) * | 2004-11-30 | 2007-09-05 | Beta O 2 Technologies Ltd. | Implantable device |
WO2008065660A2 (en) | 2006-11-28 | 2008-06-05 | Beta O2 Technologies Ltd. | Oxygen supply for cell transplant and vascularization |
EP1935442A3 (en) * | 2003-10-06 | 2008-07-02 | Activeo, LLC | Implantable apparatus for administering a therapeutic agent |
WO2010061387A2 (en) | 2008-11-26 | 2010-06-03 | Beta O2 Technologies Ltd. | Apparatus for transportation of oxygen to implanted cells |
US8066659B2 (en) | 2004-06-15 | 2011-11-29 | Ceramatec, Inc. | Apparatus and method for treating and dispensing a material into tissue |
US8066695B2 (en) | 2003-10-06 | 2011-11-29 | Ceramatec, Inc. | Implantable apparatus for administering a therapeutic agent into tissue |
JP2012031070A (en) * | 2010-07-28 | 2012-02-16 | Otsuka Pharmaceut Factory Inc | Method and device for preserving tissue |
US8353906B2 (en) | 2005-08-01 | 2013-01-15 | Ceramatec, Inc. | Electrochemical probe and method for in situ treatment of a tissue |
US8541232B2 (en) | 2006-03-08 | 2013-09-24 | Kwalata Trading Limited | Composition comprising a progenitor/precursor cell population |
WO2014055989A1 (en) * | 2012-10-05 | 2014-04-10 | University Of Southern California | Implantable oxygenator with self-contained electrolyte |
US8777889B2 (en) | 2004-06-15 | 2014-07-15 | Ceramatec, Inc. | Apparatus and method for administering a therapeutic agent into tissue |
US8821431B2 (en) | 2007-09-07 | 2014-09-02 | Beta O2 Technologies Ltd. | Air gap for supporting cells |
US9037205B2 (en) | 2011-06-30 | 2015-05-19 | Glusense, Ltd | Implantable optical glucose sensing |
US9446168B2 (en) | 2010-06-07 | 2016-09-20 | Beta-O2 Technologies Ltd. | Multiple-layer immune barrier for donor cells |
US9540630B2 (en) | 2008-09-17 | 2017-01-10 | Beta O2 Technologies Ltd. | Optimization of alginate encapsulation of islets for transplantation |
US10091985B2 (en) | 2009-06-18 | 2018-10-09 | Giner, Inc. | Perfusing an organ with an in situ generated gas |
US10231817B2 (en) | 2013-09-24 | 2019-03-19 | Giner Life Sciences, Inc. | System for gas treatment of a cell implant |
WO2019157421A1 (en) * | 2018-02-09 | 2019-08-15 | W. L. Gore & Associates, Inc. | Implantable access chamber and associated methods of use |
US10557691B2 (en) | 2016-11-15 | 2020-02-11 | Giner Life Sciences, Inc. | Self-regulating electrolytic gas generator and implant system comprising the same |
US10575765B2 (en) | 2014-10-13 | 2020-03-03 | Glusense Ltd. | Analyte-sensing device |
US10871487B2 (en) | 2016-04-20 | 2020-12-22 | Glusense Ltd. | FRET-based glucose-detection molecules |
US11033666B2 (en) | 2016-11-15 | 2021-06-15 | Giner Life Sciences, Inc. | Percutaneous gas diffusion device suitable for use with a subcutaneous implant |
US11642501B2 (en) | 2017-05-04 | 2023-05-09 | Giner, Inc. | Robust, implantable gas delivery device and methods, systems and devices including same |
US11773496B2 (en) | 2018-05-17 | 2023-10-03 | Giner, Inc. | Combined electrical lead and gas port terminals and electrolytic gas generator comprising same |
Families Citing this family (35)
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---|---|---|---|---|
US20050153309A1 (en) | 2003-12-22 | 2005-07-14 | David Hoon | Method and apparatus for in vivo surveillance of circulating biological components |
US8083710B2 (en) * | 2006-03-09 | 2011-12-27 | The Invention Science Fund I, Llc | Acoustically controlled substance delivery device |
US8936590B2 (en) * | 2005-11-09 | 2015-01-20 | The Invention Science Fund I, Llc | Acoustically controlled reaction device |
US8273071B2 (en) * | 2006-01-18 | 2012-09-25 | The Invention Science Fund I, Llc | Remote controller for substance delivery system |
US8992511B2 (en) | 2005-11-09 | 2015-03-31 | The Invention Science Fund I, Llc | Acoustically controlled substance delivery device |
US8585684B2 (en) * | 2005-11-09 | 2013-11-19 | The Invention Science Fund I, Llc | Reaction device controlled by magnetic control signal |
US9028467B2 (en) | 2005-11-09 | 2015-05-12 | The Invention Science Fund I, Llc | Osmotic pump with remotely controlled osmotic pressure generation |
US20070106271A1 (en) | 2005-11-09 | 2007-05-10 | Searete Llc, A Limited Liability Corporation | Remote control of substance delivery system |
US9067047B2 (en) | 2005-11-09 | 2015-06-30 | The Invention Science Fund I, Llc | Injectable controlled release fluid delivery system |
US20080140057A1 (en) * | 2006-03-09 | 2008-06-12 | Searete Llc, A Limited Liability Corporation Of State Of The Delaware | Injectable controlled release fluid delivery system |
US20100202966A1 (en) * | 2006-03-28 | 2010-08-12 | Yossi Gross | Implantable Sensor |
WO2008062417A2 (en) * | 2006-11-22 | 2008-05-29 | Beta O2 Technologies Ltd. | Protecting algae from body fluids |
US20100196439A1 (en) * | 2006-12-22 | 2010-08-05 | Medtronic, Inc. | Angiogenesis Mechanism and Method, and Implantable Device |
WO2008097498A1 (en) * | 2007-02-02 | 2008-08-14 | University Of Miami | Therapeutic hybrid implantable devices |
US20090182303A1 (en) * | 2008-01-14 | 2009-07-16 | Steven Walak | Targeted Therapeutic Agent Release for Weight Loss Therapy |
US20100160749A1 (en) * | 2008-12-24 | 2010-06-24 | Glusense Ltd. | Implantable optical glucose sensing |
WO2010091074A2 (en) * | 2009-02-03 | 2010-08-12 | Purdue Research Foundation | Method and apparatus for improving local hypoxicity for enhanced therapy |
US9357764B2 (en) | 2009-06-18 | 2016-06-07 | Giner, Inc. | System for fluid perfusion of biological matter comprising tissue |
US8784389B2 (en) * | 2009-08-31 | 2014-07-22 | Beta-O2 Technologies Ltd. | Oxygen supply for implantable medical device |
EP2389958A1 (en) * | 2010-03-22 | 2011-11-30 | Technische Universität Klinikum Rechts der Isar | Use of photosynthetic scaffolds in tissue engineering |
JP5783432B2 (en) * | 2011-07-29 | 2015-09-24 | トヨタ自動車株式会社 | Lithium ion secondary battery and manufacturing method thereof |
WO2014102743A1 (en) * | 2012-12-28 | 2014-07-03 | Glusense, Ltd. | Apparatus for facilitating cell growth in an implantable sensor |
US9950151B2 (en) * | 2014-03-27 | 2018-04-24 | Beta-O2 Technologies Ltd. | Implantable medical devices |
US11452740B2 (en) | 2014-09-03 | 2022-09-27 | Symbiox, Inc. | Photosynthetic cellular substances and methods of use thereof |
SG10202012275PA (en) | 2016-06-09 | 2021-01-28 | Haimachek Inc | Collector for detection and reversible capturing of cells from body fluids in vivo |
KR20230037059A (en) * | 2016-11-03 | 2023-03-15 | 아리조나 보드 오브 리전츠 온 비해프 오브 더 유니버시티 오브 아리조나 | Encapsulation device systems with oxygen sensors with or without exogenous oxygen delivery |
AU2017396754B2 (en) * | 2016-11-03 | 2021-08-05 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Methods and systems for real-time assessment of cells in encapsulation devices pre-and post-transplantation |
CA3042709A1 (en) * | 2016-11-03 | 2018-08-09 | Arizona Board Of Regents On Behalf Of The University Of Arizona | Stacked tissue encapsulation device systems with or without oxygen delivery |
AR111512A1 (en) * | 2017-02-23 | 2019-07-24 | Japan Vam & Poval Co Ltd | CELLULAR OR TISSULAR INTEGRATION DEVICE |
JP7406213B2 (en) * | 2018-01-24 | 2023-12-27 | トーマス・ジェファーソン・ユニバーシティ | Biodiffusion chamber and its manufacturing method |
WO2019222273A1 (en) * | 2018-05-14 | 2019-11-21 | Giner Life Sciences, Inc. | System and method for controlling oxygen delivery to implanted cells |
CN112492873A (en) * | 2018-05-15 | 2021-03-12 | 输出实验室公司 | Implantable devices and methods of use thereof |
CA3196876A1 (en) * | 2020-10-30 | 2022-05-05 | Klearchos Papas | Methods and systems for encapsulation devices for housing cells and agents |
WO2022125795A1 (en) * | 2020-12-09 | 2022-06-16 | Cornell University | Methods and devices for providing oxygen to encapsulated cells |
CN115025037A (en) * | 2022-06-10 | 2022-09-09 | 河北大学 | Separable microneedle loaded with active chlorella and preparation method thereof |
Citations (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4352883A (en) | 1979-03-28 | 1982-10-05 | Damon Corporation | Encapsulation of biological material |
US4402694A (en) * | 1981-07-16 | 1983-09-06 | Biotek, Inc. | Body cavity access device containing a hormone source |
US5011472A (en) * | 1988-09-06 | 1991-04-30 | Brown University Research Foundation | Implantable delivery system for biological factors |
US5101814A (en) | 1989-08-11 | 1992-04-07 | Palti Yoram Prof | System for monitoring and controlling blood glucose |
US5116494A (en) * | 1989-08-25 | 1992-05-26 | W. R. Grace & Co.-Conn. | Artificial pancreatic perfusion device with temperature sensitive matrix |
US5427935A (en) | 1987-07-24 | 1995-06-27 | The Regents Of The University Of Michigan | Hybrid membrane bead and process for encapsulating materials in semi-permeable hybrid membranes |
US5741334A (en) * | 1995-06-07 | 1998-04-21 | Circe Biomedical, Inc. | Artificial pancreatic perfusion device |
US5834005A (en) | 1992-02-24 | 1998-11-10 | Encelle, Inc. | Bioartificial devices and cellular matrices therefor |
US5855613A (en) | 1995-10-13 | 1999-01-05 | Islet Sheet Medical, Inc. | Retrievable bioartificial implants having dimensions allowing rapid diffusion of oxygen and rapid biological response to physiological change |
US5879709A (en) | 1991-11-25 | 1999-03-09 | Vivorx, Inc. | Method of treating patients with diabetes |
US5902745A (en) | 1995-09-22 | 1999-05-11 | Gore Hybrid Technologies, Inc. | Cell encapsulation device |
US5912005A (en) | 1994-04-15 | 1999-06-15 | Biohybrid Technologies, Inc. | Methods of use of uncoated gel particles |
US6091974A (en) * | 1994-06-27 | 2000-07-18 | Carmel Biosensors Ltd | Implantable capsule for enhancing cell electric signals |
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US4631053A (en) * | 1984-03-19 | 1986-12-23 | Taheri Syde A | Oxygenator |
US4680268A (en) | 1985-09-18 | 1987-07-14 | Children's Hospital Medical Center | Implantable gas-containing biosensor and method for measuring an analyte such as glucose |
US5614378A (en) * | 1990-06-28 | 1997-03-25 | The Regents Of The University Of Michigan | Photobioreactors and closed ecological life support systems and artifificial lungs containing the same |
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US5262055A (en) | 1992-10-19 | 1993-11-16 | The University Of Utah | Implantable and refillable biohybrid artificial pancreas |
US6368592B1 (en) | 1998-07-17 | 2002-04-09 | Massachusetts Institute Of Technology | Method of delivering oxygen to cells by electrolyzing water |
US6562616B1 (en) * | 1999-06-21 | 2003-05-13 | The General Hospital Corporation | Methods and devices for cell culturing and organ assist systems |
US8012500B2 (en) | 2000-01-01 | 2011-09-06 | Beta-O2 Technologies Ltd. | Implantable device |
WO2008065660A2 (en) | 2006-11-28 | 2008-06-05 | Beta O2 Technologies Ltd. | Oxygen supply for cell transplant and vascularization |
US7332330B2 (en) | 2001-09-11 | 2008-02-19 | Renamed Biologics, Inc. | Device for maintaining vascularization near an implant |
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US8821431B2 (en) | 2007-09-07 | 2014-09-02 | Beta O2 Technologies Ltd. | Air gap for supporting cells |
-
2000
- 2000-01-12 IL IL134009A patent/IL134009A/en not_active IP Right Cessation
-
2001
- 2001-01-12 DE DE60111267T patent/DE60111267T2/en not_active Expired - Lifetime
- 2001-01-12 EP EP01900607A patent/EP1351623B1/en not_active Expired - Lifetime
- 2001-01-12 DK DK01900607T patent/DK1351623T3/en active
- 2001-01-12 WO PCT/IL2001/000031 patent/WO2001050983A1/en active IP Right Grant
- 2001-01-12 ES ES01900607T patent/ES2239662T3/en not_active Expired - Lifetime
- 2001-01-12 AT AT05011703T patent/ATE380526T1/en not_active IP Right Cessation
- 2001-01-12 AU AU25442/01A patent/AU2544201A/en not_active Abandoned
- 2001-01-12 DE DE60131913T patent/DE60131913T2/en not_active Expired - Lifetime
- 2001-01-12 EP EP05011703A patent/EP1645243B1/en not_active Expired - Lifetime
- 2001-01-12 ES ES05011703T patent/ES2299916T3/en not_active Expired - Lifetime
- 2001-01-12 US US10/466,069 patent/US7892222B2/en active Active
- 2001-01-12 AT AT01900607T patent/ATE296589T1/en not_active IP Right Cessation
- 2001-01-12 DK DK05011703T patent/DK1645243T3/en active
Patent Citations (13)
Publication number | Priority date | Publication date | Assignee | Title |
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US4352883A (en) | 1979-03-28 | 1982-10-05 | Damon Corporation | Encapsulation of biological material |
US4402694A (en) * | 1981-07-16 | 1983-09-06 | Biotek, Inc. | Body cavity access device containing a hormone source |
US5427935A (en) | 1987-07-24 | 1995-06-27 | The Regents Of The University Of Michigan | Hybrid membrane bead and process for encapsulating materials in semi-permeable hybrid membranes |
US5011472A (en) * | 1988-09-06 | 1991-04-30 | Brown University Research Foundation | Implantable delivery system for biological factors |
US5101814A (en) | 1989-08-11 | 1992-04-07 | Palti Yoram Prof | System for monitoring and controlling blood glucose |
US5116494A (en) * | 1989-08-25 | 1992-05-26 | W. R. Grace & Co.-Conn. | Artificial pancreatic perfusion device with temperature sensitive matrix |
US5879709A (en) | 1991-11-25 | 1999-03-09 | Vivorx, Inc. | Method of treating patients with diabetes |
US5834005A (en) | 1992-02-24 | 1998-11-10 | Encelle, Inc. | Bioartificial devices and cellular matrices therefor |
US5912005A (en) | 1994-04-15 | 1999-06-15 | Biohybrid Technologies, Inc. | Methods of use of uncoated gel particles |
US6091974A (en) * | 1994-06-27 | 2000-07-18 | Carmel Biosensors Ltd | Implantable capsule for enhancing cell electric signals |
US5741334A (en) * | 1995-06-07 | 1998-04-21 | Circe Biomedical, Inc. | Artificial pancreatic perfusion device |
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Cited By (44)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8012500B2 (en) | 2000-01-01 | 2011-09-06 | Beta-O2 Technologies Ltd. | Implantable device |
US8444630B2 (en) | 2000-01-12 | 2013-05-21 | Beta-O2 Technologies Ltd. | Oxygen supply for cell transplant and vascularization |
JP2003190259A (en) * | 2001-12-28 | 2003-07-08 | Hisako Ogawara | Chamber for artificial organ |
US8162873B2 (en) | 2003-10-06 | 2012-04-24 | Ceramatec, Inc. | Apparatus for administering a therapeutic agent into tissue |
US8066695B2 (en) | 2003-10-06 | 2011-11-29 | Ceramatec, Inc. | Implantable apparatus for administering a therapeutic agent into tissue |
EP1935442A3 (en) * | 2003-10-06 | 2008-07-02 | Activeo, LLC | Implantable apparatus for administering a therapeutic agent |
US8777889B2 (en) | 2004-06-15 | 2014-07-15 | Ceramatec, Inc. | Apparatus and method for administering a therapeutic agent into tissue |
US8066659B2 (en) | 2004-06-15 | 2011-11-29 | Ceramatec, Inc. | Apparatus and method for treating and dispensing a material into tissue |
US8986520B2 (en) | 2004-06-15 | 2015-03-24 | Ceramatec, Inc. | Apparatus administering a therapeutic agent into tissue |
US8591472B2 (en) | 2004-06-15 | 2013-11-26 | Ceramatec, Inc. | Apparatus for administering a therapeutic agent into tissue using a needle as the material treatment module |
EP2532356A1 (en) | 2004-07-14 | 2012-12-12 | Glusense Ltd. | Implantable power sources and sensors |
US7951357B2 (en) | 2004-07-14 | 2011-05-31 | Glusense Ltd. | Implantable power sources and sensors |
WO2006006166A2 (en) | 2004-07-14 | 2006-01-19 | Glusense, Ltd. | Implantable power sources and sensors |
JP2008521538A (en) * | 2004-11-30 | 2008-06-26 | ベタ オー2 テクノロジーズ リミティド | Implantable device |
EP1827490A4 (en) * | 2004-11-30 | 2012-08-01 | Beta O 2 Technologies Ltd | Implantable device |
EP1827490A2 (en) * | 2004-11-30 | 2007-09-05 | Beta O 2 Technologies Ltd. | Implantable device |
US8353906B2 (en) | 2005-08-01 | 2013-01-15 | Ceramatec, Inc. | Electrochemical probe and method for in situ treatment of a tissue |
US10358629B2 (en) | 2006-03-08 | 2019-07-23 | Kwalata Trading Limited | Regulating stem cells |
US8541232B2 (en) | 2006-03-08 | 2013-09-24 | Kwalata Trading Limited | Composition comprising a progenitor/precursor cell population |
US9234173B2 (en) | 2006-03-08 | 2016-01-12 | Kwalata Trading Ltd. | Regulating stem cells |
EP2104492A4 (en) * | 2006-11-28 | 2014-10-22 | Beta O2 Technologies Ltd | Oxygen supply for cell transplant and vascularization |
WO2008065660A2 (en) | 2006-11-28 | 2008-06-05 | Beta O2 Technologies Ltd. | Oxygen supply for cell transplant and vascularization |
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Also Published As
Publication number | Publication date |
---|---|
IL134009A0 (en) | 2001-04-30 |
DE60131913T2 (en) | 2008-12-04 |
ATE380526T1 (en) | 2007-12-15 |
DE60131913D1 (en) | 2008-01-24 |
AU2544201A (en) | 2001-07-24 |
US7892222B2 (en) | 2011-02-22 |
IL134009A (en) | 2011-07-31 |
DK1645243T3 (en) | 2008-04-21 |
EP1351623A1 (en) | 2003-10-15 |
DK1351623T3 (en) | 2005-09-19 |
DE60111267T2 (en) | 2005-10-27 |
EP1645243A3 (en) | 2006-05-17 |
ES2299916T3 (en) | 2008-06-01 |
EP1645243B1 (en) | 2007-12-12 |
ATE296589T1 (en) | 2005-06-15 |
DE60111267D1 (en) | 2005-07-07 |
US20040133188A1 (en) | 2004-07-08 |
ES2239662T3 (en) | 2005-10-01 |
EP1351623B1 (en) | 2005-06-01 |
EP1645243A2 (en) | 2006-04-12 |
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