WO2001057238A3 - Electrochemical test strip for use in analyte determination - Google Patents

Electrochemical test strip for use in analyte determination Download PDF

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Publication number
WO2001057238A3
WO2001057238A3 PCT/US2001/002510 US0102510W WO0157238A3 WO 2001057238 A3 WO2001057238 A3 WO 2001057238A3 US 0102510 W US0102510 W US 0102510W WO 0157238 A3 WO0157238 A3 WO 0157238A3
Authority
WO
WIPO (PCT)
Prior art keywords
detection
electrochemical test
test strips
subject
end group
Prior art date
Application number
PCT/US2001/002510
Other languages
French (fr)
Other versions
WO2001057238A2 (en
Inventor
Yeung Siu Yu
Mahesh Shah
Original Assignee
Lifescan Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CA2388272A priority Critical patent/CA2388272C/en
Application filed by Lifescan Inc filed Critical Lifescan Inc
Priority to JP2001558050A priority patent/JP4070999B2/en
Priority to MXPA02005796A priority patent/MXPA02005796A/en
Priority to EP01906688A priority patent/EP1254365B1/en
Priority to DE60140600T priority patent/DE60140600D1/en
Priority to IL14966101A priority patent/IL149661A0/en
Priority to PL01358134A priority patent/PL358134A1/en
Priority to AU34569/01A priority patent/AU778966C/en
Priority to AT01906688T priority patent/ATE449961T1/en
Publication of WO2001057238A2 publication Critical patent/WO2001057238A2/en
Publication of WO2001057238A3 publication Critical patent/WO2001057238A3/en
Priority to HK03102011.8A priority patent/HK1050047B/en
Priority to AU2005201227A priority patent/AU2005201227B2/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y15/00—Nanotechnology for interacting, sensing or actuating, e.g. quantum dots as markers in protein assays or molecular motors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/001—Enzyme electrodes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • G01N33/5438—Electrodes

Abstract

Electrochemical test strips and methods for their use in the detection of an analyte in a physiological sample are provided. The subject test strips have a reaction zone defined by opposing metal electrodes separated by a thin spacer layer. The metal surface of at least one of the electrodes is modified by a homogenous surface modification layer made up of linear self-assembling molecules having a first sulfhydryl end group and a second sulfonate end group separated by a short chain alkyl linking group, where 2-mercaptoethane sulfonic acid or a salt thereof is preferred in certain embodiments. The subject electrochemical test strips find application in the detection of a wide variety of analytes, and are particularly suited for use the detection of glucose.
PCT/US2001/002510 2000-02-02 2001-01-25 Electrochemical test strip for use in analyte determination WO2001057238A2 (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
IL14966101A IL149661A0 (en) 2000-02-02 2001-01-25 Electrochemical test strip for use in analyte determination
JP2001558050A JP4070999B2 (en) 2000-02-02 2001-01-25 Electrochemical test strip for analyte measurement
MXPA02005796A MXPA02005796A (en) 2000-02-02 2001-01-25 Electrochemical test strip for use in analyte determination.
EP01906688A EP1254365B1 (en) 2000-02-02 2001-01-25 Electrochemical test strip for use in analyte determination
DE60140600T DE60140600D1 (en) 2000-02-02 2001-01-25 ELECTROCHEMICAL TEST STRIP FOR USE IN ANALYTE DETERMINATION
CA2388272A CA2388272C (en) 2000-02-02 2001-01-25 Electrochemical test strip for use in analyte determination
PL01358134A PL358134A1 (en) 2000-02-02 2001-01-25 Electrochemical test strip for use in analyte determination
AU34569/01A AU778966C (en) 2000-02-02 2001-01-25 Electrochemical test strip for use in analyte determination
AT01906688T ATE449961T1 (en) 2000-02-02 2001-01-25 ELECTROCHEMICAL TEST STRIP FOR USE IN ANALYTE DETERMINATION
HK03102011.8A HK1050047B (en) 2000-02-02 2003-03-18 Electrochemical test strip for use in analyte determination
AU2005201227A AU2005201227B2 (en) 2000-02-02 2005-03-22 Electrochemical test strip for use in analyte determination

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/497,269 US6716577B1 (en) 2000-02-02 2000-02-02 Electrochemical test strip for use in analyte determination
US09/497,269 2000-02-02

Publications (2)

Publication Number Publication Date
WO2001057238A2 WO2001057238A2 (en) 2001-08-09
WO2001057238A3 true WO2001057238A3 (en) 2002-04-18

Family

ID=23976142

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/002510 WO2001057238A2 (en) 2000-02-02 2001-01-25 Electrochemical test strip for use in analyte determination

Country Status (20)

Country Link
US (2) US6716577B1 (en)
EP (1) EP1254365B1 (en)
JP (1) JP4070999B2 (en)
KR (1) KR100856342B1 (en)
CN (1) CN1394278A (en)
AR (1) AR027347A1 (en)
AT (1) ATE449961T1 (en)
AU (2) AU778966C (en)
CA (1) CA2388272C (en)
CZ (1) CZ20022946A3 (en)
DE (1) DE60140600D1 (en)
ES (1) ES2334883T3 (en)
HK (1) HK1050047B (en)
IL (1) IL149661A0 (en)
MX (1) MXPA02005796A (en)
MY (1) MY133963A (en)
PL (1) PL358134A1 (en)
RU (1) RU2256171C2 (en)
TW (1) TW593680B (en)
WO (1) WO2001057238A2 (en)

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