WO2001057264A3 - Electron-deficient nitrogen heterocycle-substituted fluorescein dyes - Google Patents
Electron-deficient nitrogen heterocycle-substituted fluorescein dyes Download PDFInfo
- Publication number
- WO2001057264A3 WO2001057264A3 PCT/US2001/003772 US0103772W WO0157264A3 WO 2001057264 A3 WO2001057264 A3 WO 2001057264A3 US 0103772 W US0103772 W US 0103772W WO 0157264 A3 WO0157264 A3 WO 0157264A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- electron
- deficient nitrogen
- nitrogen heterocycle
- fluorescein dyes
- substituted fluorescein
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B11/00—Diaryl- or thriarylmethane dyes
- C09B11/04—Diaryl- or thriarylmethane dyes derived from triarylmethanes, i.e. central C-atom is substituted by amino, cyano, alkyl
- C09B11/06—Hydroxy derivatives of triarylmethanes in which at least one OH group is bound to an aryl nucleus and their ethers or esters
- C09B11/08—Phthaleins; Phenolphthaleins; Fluorescein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/80—Fluorescent dyes, e.g. rhodamine
Abstract
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002368495A CA2368495C (en) | 2000-02-07 | 2001-02-05 | Electron-deficient nitrogen heterocycle-substituted fluorescein dyes |
AU34839/01A AU772739B2 (en) | 2000-02-07 | 2001-02-05 | Electron-deficient nitrogen heterocycle-substituted fluorescein dyes |
JP2001555887A JP2003521571A (en) | 2000-02-07 | 2001-02-05 | Fluorescein dye substituted with electron-deficient nitrogen heterocycle |
DE60101939T DE60101939T2 (en) | 2000-02-07 | 2001-02-05 | NITROGEN HETEROCYCLES SUBSTITUTED ELECTRON SHORT FLUORESCEIN DYES |
EP01907003A EP1196640B1 (en) | 2000-02-07 | 2001-02-05 | Electron-deficient nitrogen heterocycle-substituted fluorescein dyes |
AT01907003T ATE258992T1 (en) | 2000-02-07 | 2001-02-05 | ELECTRON DEFICIENCY FLUORESCEIN DYES SUBSTITUTED WITH NITROGEN HETEROCYCLES |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/498,702 US6221604B1 (en) | 2000-02-07 | 2000-02-07 | Electron-deficient nitrogen heterocycle-substituted fluorescein dyes |
US09/498,702 | 2000-02-07 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2001057264A2 WO2001057264A2 (en) | 2001-08-09 |
WO2001057264A3 true WO2001057264A3 (en) | 2002-02-21 |
Family
ID=23982139
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2001/003772 WO2001057264A2 (en) | 2000-02-07 | 2001-02-05 | Electron-deficient nitrogen heterocycle-substituted fluorescein dyes |
Country Status (9)
Country | Link |
---|---|
US (2) | US6221604B1 (en) |
EP (1) | EP1196640B1 (en) |
JP (5) | JP2003521571A (en) |
AT (1) | ATE258992T1 (en) |
AU (1) | AU772739B2 (en) |
CA (1) | CA2368495C (en) |
DE (1) | DE60101939T2 (en) |
ES (1) | ES2211768T3 (en) |
WO (1) | WO2001057264A2 (en) |
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US20050255485A1 (en) * | 2004-05-14 | 2005-11-17 | Livak Kenneth J | Detection of gene duplications |
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Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
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WO1994005688A1 (en) * | 1992-09-03 | 1994-03-17 | Applied Biosystems, Inc. | 4,7-dichlorofluorescein dyes as molecular probes |
WO1997036960A1 (en) * | 1996-04-01 | 1997-10-09 | The Perkin-Elmer Corporation | Asymmetric benzoxanthene dyes |
US5800996A (en) * | 1996-05-03 | 1998-09-01 | The Perkin Elmer Corporation | Energy transfer dyes with enchanced fluorescence |
US5885778A (en) * | 1989-11-14 | 1999-03-23 | The Perkin-Elmer Corporation | 4, 7-dichlorofluorescein dyes as molecular probes |
WO1999015517A1 (en) * | 1997-09-23 | 1999-04-01 | Molecular Probes, Inc. | Sulfonated xanthene derivatives |
WO1999016832A1 (en) * | 1997-10-01 | 1999-04-08 | The Perkin-Elmer Corporation | Aromatic-substituted xanthene dyes |
Family Cites Families (12)
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US4318846A (en) | 1979-09-07 | 1982-03-09 | Syva Company | Novel ether substituted fluorescein polyamino acid compounds as fluorescers and quenchers |
US5047519A (en) | 1986-07-02 | 1991-09-10 | E. I. Du Pont De Nemours And Company | Alkynylamino-nucleotides |
CA1340806C (en) | 1986-07-02 | 1999-11-02 | James Merrill Prober | Method, system and reagents for dna sequencing |
US5188934A (en) | 1989-11-14 | 1993-02-23 | Applied Biosystems, Inc. | 4,7-dichlorofluorescein dyes as molecular probes |
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US6221604B1 (en) * | 2000-02-07 | 2001-04-24 | Pe Corporation | Electron-deficient nitrogen heterocycle-substituted fluorescein dyes |
-
2000
- 2000-02-07 US US09/498,702 patent/US6221604B1/en not_active Ceased
-
2001
- 2001-02-05 DE DE60101939T patent/DE60101939T2/en not_active Expired - Lifetime
- 2001-02-05 CA CA002368495A patent/CA2368495C/en not_active Expired - Lifetime
- 2001-02-05 AT AT01907003T patent/ATE258992T1/en not_active IP Right Cessation
- 2001-02-05 ES ES01907003T patent/ES2211768T3/en not_active Expired - Lifetime
- 2001-02-05 WO PCT/US2001/003772 patent/WO2001057264A2/en active IP Right Grant
- 2001-02-05 JP JP2001555887A patent/JP2003521571A/en active Pending
- 2001-02-05 AU AU34839/01A patent/AU772739B2/en not_active Expired
- 2001-02-05 EP EP01907003A patent/EP1196640B1/en not_active Expired - Lifetime
-
2004
- 2004-04-06 US US10/819,078 patent/USRE39663E1/en not_active Expired - Lifetime
-
2005
- 2005-09-02 JP JP2005255770A patent/JP2006070270A/en not_active Withdrawn
-
2006
- 2006-03-20 JP JP2006077798A patent/JP4942150B2/en not_active Expired - Lifetime
-
2007
- 2007-05-08 JP JP2007124005A patent/JP2007277565A/en active Pending
- 2007-05-08 JP JP2007124004A patent/JP2007277564A/en active Pending
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
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US5885778A (en) * | 1989-11-14 | 1999-03-23 | The Perkin-Elmer Corporation | 4, 7-dichlorofluorescein dyes as molecular probes |
WO1994005688A1 (en) * | 1992-09-03 | 1994-03-17 | Applied Biosystems, Inc. | 4,7-dichlorofluorescein dyes as molecular probes |
WO1997036960A1 (en) * | 1996-04-01 | 1997-10-09 | The Perkin-Elmer Corporation | Asymmetric benzoxanthene dyes |
US5840999A (en) * | 1996-04-01 | 1998-11-24 | The Perkin-Elmer Corporation | Asymmetric benzoxanthene dyes |
US5800996A (en) * | 1996-05-03 | 1998-09-01 | The Perkin Elmer Corporation | Energy transfer dyes with enchanced fluorescence |
EP0940450A1 (en) * | 1996-05-03 | 1999-09-08 | Perkin-Elmer Corporation | Energy transfer dyes with enhanced fluorescence |
WO1999015517A1 (en) * | 1997-09-23 | 1999-04-01 | Molecular Probes, Inc. | Sulfonated xanthene derivatives |
WO1999016832A1 (en) * | 1997-10-01 | 1999-04-08 | The Perkin-Elmer Corporation | Aromatic-substituted xanthene dyes |
Also Published As
Publication number | Publication date |
---|---|
USRE39663E1 (en) | 2007-05-29 |
ATE258992T1 (en) | 2004-02-15 |
JP2003521571A (en) | 2003-07-15 |
US6221604B1 (en) | 2001-04-24 |
JP2006070270A (en) | 2006-03-16 |
EP1196640A2 (en) | 2002-04-17 |
JP4942150B2 (en) | 2012-05-30 |
CA2368495C (en) | 2009-09-29 |
AU3483901A (en) | 2001-08-14 |
ES2211768T3 (en) | 2004-07-16 |
DE60101939D1 (en) | 2004-03-11 |
AU772739B2 (en) | 2004-05-06 |
WO2001057264A2 (en) | 2001-08-09 |
DE60101939T2 (en) | 2005-01-05 |
JP2007277565A (en) | 2007-10-25 |
JP2007277564A (en) | 2007-10-25 |
CA2368495A1 (en) | 2001-08-09 |
JP2006257427A (en) | 2006-09-28 |
EP1196640B1 (en) | 2004-02-04 |
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