WO2001075067A3 - Novel nucleic acids and polypeptides - Google Patents

Novel nucleic acids and polypeptides Download PDF

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Publication number
WO2001075067A3
WO2001075067A3 PCT/US2001/008631 US0108631W WO0175067A3 WO 2001075067 A3 WO2001075067 A3 WO 2001075067A3 US 0108631 W US0108631 W US 0108631W WO 0175067 A3 WO0175067 A3 WO 0175067A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acids
polypeptides
novel nucleic
novel
present
Prior art date
Application number
PCT/US2001/008631
Other languages
French (fr)
Other versions
WO2001075067A2 (en
WO2001075067A9 (en
WO2001075067A8 (en
Inventor
Rodoje T Drmanac
Chenghua Liu
Y Tom Tang
Original Assignee
Hyseq Inc
Rodoje T Drmanac
Chenghua Liu
Y Tom Tang
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hyseq Inc, Rodoje T Drmanac, Chenghua Liu, Y Tom Tang filed Critical Hyseq Inc
Priority to US10/450,763 priority Critical patent/US20050196754A1/en
Priority to AU2001249251A priority patent/AU2001249251A1/en
Publication of WO2001075067A2 publication Critical patent/WO2001075067A2/en
Publication of WO2001075067A3 publication Critical patent/WO2001075067A3/en
Priority to US10/128,558 priority patent/US20040219521A1/en
Priority to US10/243,552 priority patent/US20030224379A1/en
Publication of WO2001075067A9 publication Critical patent/WO2001075067A9/en
Priority to US10/302,689 priority patent/US20080050393A1/en
Publication of WO2001075067A8 publication Critical patent/WO2001075067A8/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

The present invention provides novel nucleic acids, novel polypeptide sequences encoded by these nucleic acids and uses thereof.
PCT/US2001/008631 1998-12-03 2001-03-30 Novel nucleic acids and polypeptides WO2001075067A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
US10/450,763 US20050196754A1 (en) 2000-03-31 2001-03-30 Novel nucleic acids and polypeptides
AU2001249251A AU2001249251A1 (en) 2000-03-31 2001-03-30 Novel nucleic acids and polypeptides
US10/128,558 US20040219521A1 (en) 2000-01-21 2002-04-22 Novel nucleic acids and polypeptides
US10/243,552 US20030224379A1 (en) 2000-01-21 2002-09-12 Novel nucleic acids and polypeptides
US10/302,689 US20080050393A1 (en) 1998-12-03 2002-11-22 Novel nucleic acids and polypeptides

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US54021700A 2000-03-31 2000-03-31
US09/540,217 2000-03-31
US64916700A 2000-08-23 2000-08-23
US09/649,167 2000-08-23

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/008656 Continuation-In-Part WO2001079449A2 (en) 1998-12-03 2001-04-16 Novel nucleic acids and polypeptides

Related Child Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/004941 Continuation-In-Part WO2002016439A2 (en) 1998-12-03 2001-03-05 Novel nucleic acids and polypeptides

Publications (4)

Publication Number Publication Date
WO2001075067A2 WO2001075067A2 (en) 2001-10-11
WO2001075067A3 true WO2001075067A3 (en) 2002-04-04
WO2001075067A9 WO2001075067A9 (en) 2002-10-31
WO2001075067A8 WO2001075067A8 (en) 2004-10-14

Family

ID=27066367

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/008631 WO2001075067A2 (en) 1998-12-03 2001-03-30 Novel nucleic acids and polypeptides

Country Status (3)

Country Link
US (7) US6436703B1 (en)
AU (1) AU2001249251A1 (en)
WO (1) WO2001075067A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9409942B2 (en) 1997-01-08 2016-08-09 Life Technologies Corporation Methods for production of proteins

Families Citing this family (565)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7125677B2 (en) 1995-11-13 2006-10-24 The Salk Institute For Biological Studies NIMA interacting proteins
US5972697A (en) 1995-11-13 1999-10-26 The Salk Institute For Biological Studies NIMA interacting proteins
US7351421B2 (en) * 1996-11-05 2008-04-01 Hsing-Wen Sung Drug-eluting stent having collagen drug carrier chemically treated with genipin
US20050163818A1 (en) * 1996-11-05 2005-07-28 Hsing-Wen Sung Drug-eluting device chemically treated with genipin
US20030108983A1 (en) * 1997-09-17 2003-06-12 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US7417126B2 (en) * 1997-10-17 2008-08-26 Genentech, Inc. PRO246 antibodies
JP2002504331A (en) * 1998-02-19 2002-02-12 スミスクライン ビーチャム コーポレーション G protein-coupled receptor AmMaid
US6960570B2 (en) 1998-03-18 2005-11-01 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
US7258860B2 (en) 1998-03-18 2007-08-21 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
US7579160B2 (en) 1998-03-18 2009-08-25 Corixa Corporation Methods for the detection of cervical cancer
US6696247B2 (en) 1998-03-18 2004-02-24 Corixa Corporation Compounds and methods for therapy and diagnosis of lung cancer
US6833438B1 (en) 1999-06-01 2004-12-21 Agensys, Inc. Serpentine transmembrane antigens expressed in human cancers and uses thereof
US20030149531A1 (en) 2000-12-06 2003-08-07 Hubert Rene S. Serpentine transmembrane antigens expressed in human cancers and uses thereof
EP2080802B1 (en) 1998-06-01 2017-03-29 Agensys, Inc. Novel serpentine transmembrane antigens expressed in human cancers and uses thereof
US7339033B2 (en) * 1998-06-26 2008-03-04 Genentech, Inc. Pro1481
US7091315B1 (en) 1998-07-15 2006-08-15 Human Genome Sciences, Inc. Protein HDPBQ71
US20030229216A1 (en) * 1998-10-13 2003-12-11 Ruoping Chen Constitutively activated human G protein coupled receptors
US20070072248A1 (en) * 1998-10-13 2007-03-29 Arena Pharmaceuticals, Inc. Constitutively activated human G protein coupled receptors
US7041474B2 (en) 1998-12-30 2006-05-09 Millennium Pharmaceuticals, Inc. Nucleic acid encoding human tango 509
US20080213778A1 (en) 1998-12-30 2008-09-04 Millennium Pharmaceuticals, Inc. Novel genes encoding proteins having prognostic, diagnostic, preventive, therapeutic, and other uses
US7235642B1 (en) * 1999-01-12 2007-06-26 Genentech, Inc. Anti-PRO 1313 antibodies
US6303321B1 (en) 1999-02-11 2001-10-16 North Shore-Long Island Jewish Research Institute Methods for diagnosing sepsis
US7465785B2 (en) 1999-03-08 2008-12-16 Genentech, Inc. Polypeptide encoded by a nucleic acid over-expressed in melanoma
US6649342B1 (en) 1999-03-15 2003-11-18 Eos Biotechnology, Inc. Methods of diagnosing breast cancer, compositions, and methods of screening for breast cancer modulators
US6943235B1 (en) 1999-04-12 2005-09-13 Agensys, Inc. Transmembrane protein expressed in prostate cancer
EP1268506A4 (en) * 1999-07-30 2004-07-28 Millennium Pharm Inc Secreted proteins and uses thereof
EP1218411A4 (en) * 1999-09-20 2004-09-01 Millennium Pharm Inc Secreted proteins and uses thereof
US20030228640A1 (en) * 1999-10-15 2003-12-11 University Of Pittsburgh Nuclear matrix proteins, polynucleotide sequences encoding them, and their use
CA2496312A1 (en) * 1999-12-01 2001-06-07 Kevin P. Baker Colon tumour marker pro4799 polypeptides and nucleic acids encoding the same
AU2050501A (en) * 1999-12-01 2001-06-12 Human Genome Sciences, Inc. Four disulfide core domain-containing (fdcd) polynucleotides, polypeptides, and antibodies
AU3797301A (en) 2000-01-26 2001-08-07 Urogenesys Inc 84p2a9: a prostate and testis specific protein highly expressed in prostate cancer
AU2001236658A1 (en) * 2000-02-03 2001-08-14 Nuvelo, Inc. Methods and materials relating to neurotrimin-like polypeptides and polynucleotides
US6806254B2 (en) * 2000-02-03 2004-10-19 Nuvelo, Inc. Methods and materials relating to alpha-2-macroglobulin-like polypeptides and polynucleotides
US7700341B2 (en) 2000-02-03 2010-04-20 Dendreon Corporation Nucleic acid molecules encoding transmembrane serine proteases, the encoded proteins and methods based thereon
WO2001057214A2 (en) * 2000-02-03 2001-08-09 Lexicon Genetics Incorporated Human transporter proteins and polynucleotides encoding the same
DE60122488T2 (en) * 2000-03-22 2007-10-04 Bayer Healthcare Ag Use of the Human Latrophilin-like G Protein-coupled Receptor in Screening Procedures
WO2001075075A2 (en) * 2000-03-27 2001-10-11 Bayer Aktiengesellschaft Human tyrosine phosphatase-like enzymes
CA2404555A1 (en) * 2000-03-31 2001-10-11 Hyseq, Inc. Novel nucleic acids and polypeptides
WO2001075064A2 (en) * 2000-03-31 2001-10-11 Hyseq, Inc. Method and materials relating to insulin-like growth factor binding protein-like polypeptides and polynucleotides
US6436703B1 (en) * 2000-03-31 2002-08-20 Hyseq, Inc. Nucleic acids and polypeptides
GB0008305D0 (en) * 2000-04-06 2000-05-24 Neutec Pharma Plc Treatment of fungal infections
CA2405985A1 (en) * 2000-04-19 2001-11-01 Claudia Wilm Nk-2 homeobox transcription factor
US7371388B1 (en) 2000-05-04 2008-05-13 Human Genome Sciences, Inc. Treatment of Sjogren's syndrome by administration of TR18 polypeptides
AU6531101A (en) * 2000-06-02 2001-12-17 Genentech Inc Secreted and transmembrane polypeptides and nucleic acids encoding the same
US7078184B2 (en) 2000-06-06 2006-07-18 Millennium Pharmaceuticals, Inc. 52906 Potassium channel nucleic acids and uses therefor
WO2001094614A2 (en) * 2000-06-07 2001-12-13 Cyclacel Limited Methods for monitoring enzyme activity
WO2001096378A2 (en) * 2000-06-12 2001-12-20 Bayer Aktiengesellschaft Human epithin-like serine protease
WO2001098341A1 (en) * 2000-06-22 2001-12-27 Takeda Chemical Industries, Ltd. Novel polypeptide and its dna
DE60117155T2 (en) * 2000-06-23 2006-09-28 Bayer Healthcare Ag REGULATION OF HUMAN PROSTASINE-SENSE SERINE PROTEASE
WO2002000714A2 (en) * 2000-06-26 2002-01-03 Merck Patent Gmbh Receptor for phosphoinositides-1 associated scaffold protein
DK1325115T3 (en) * 2000-06-26 2016-11-21 Zymogenetics Inc CYTOKINRECEPTOR ZCYTOR17
EP1294882A2 (en) * 2000-06-28 2003-03-26 Amgen, Inc. B7-like molecules and uses thereof
US7355023B2 (en) * 2000-06-29 2008-04-08 Duke University Isolated nucleic acids and polypeptides associated with glucose homeostasis disorders and method of detecting the same
US20020064821A1 (en) * 2000-07-05 2002-05-30 Merkulov Gennady V. Isolated human ion channel proteins, nucleic acid molecules encoding human ion channel proteins, and uses thereof
JP2004504026A (en) * 2000-07-18 2004-02-12 バイエル　アクチェンゲゼルシャフト Regulation of human DESC1-like serine protease
WO2002008392A2 (en) * 2000-07-25 2002-01-31 Bayer Aktiengesellschaft Regulation of human matriptase-like serine protease
JP2004527210A (en) 2000-08-02 2004-09-09 ザ ジョンズ ホプキンス ユニバーシティー Evaluation method of endothelial cell expression pattern
WO2002012330A2 (en) * 2000-08-04 2002-02-14 Zymogenetics, Inc. Human secreted protein, zzp1
AU2001281197A1 (en) * 2000-08-09 2002-02-18 Millennium Pharmaceuticals, Inc. A human adenylate kinase family member and uses therefor
ATE397015T1 (en) * 2000-08-21 2008-06-15 Organon Nv COASTER, A HUMAN COACTIVATOR OF STEROID RECEPTORS
JPWO2002024738A1 (en) 2000-09-22 2004-01-29 協和醗酵工業株式会社 β-catenin nuclear localization protein
AU2001291235A1 (en) * 2000-09-25 2002-04-08 Millenium Pharmaceuticals, Inc. 22108 and 47916, novel human thioredoxin family members and uses thereof
AU2002210514A1 (en) * 2000-09-27 2002-04-08 Bayer Aktiengesellschaft Regulation of human phosphatidylinositol-specific phospholipase c-like enzyme
CA2424199A1 (en) * 2000-10-05 2002-04-11 Curagen Corporation Novel human proteins, polynucleotides encoding them and methods of using the same
AU2001293863A1 (en) * 2000-10-05 2002-04-15 Bayer Aktiengesellschaft Regulation of human sodium-dependent monoamine transporter
US20030124704A1 (en) * 2000-10-06 2003-07-03 Strittmatter Stephen M. Nogo receptor homologs
US20030190715A1 (en) * 2000-10-12 2003-10-09 Grosse William M. Novel proteins and nucleic acids encoding same
EP1326979A2 (en) * 2000-10-18 2003-07-16 ZymoGenetics, Inc. Human cyclic nucleotide binding protein
CA2464121C (en) * 2000-10-20 2013-08-13 Como Biotech Aps Pregnancy-associated plasma protein-a2 (papp-a2)
US20030068624A1 (en) * 2000-10-26 2003-04-10 Recipon Herve E. Compositions and methods relating to lung specific genes and proteins
AU2002243444A1 (en) 2000-10-31 2002-06-24 Diadexus, Inc. Compositions and methods relating to colon specific genes and proteins
WO2002050278A2 (en) * 2000-11-15 2002-06-27 Lexicon Genetics Incorporated Novel human secreted proteins and polynucleotides encoding the same
AU2001297770B2 (en) 2000-11-22 2007-04-05 University Of Maryland, Baltimore Use of CLyA hemolysin for excretion of fusion proteins
WO2002042435A2 (en) * 2000-11-27 2002-05-30 Bayer Aktiengesellschaft Regulation of human tyrosine phosphatase
US20020081653A1 (en) * 2000-11-28 2002-06-27 Chunhua Yan Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof
EP2336368A1 (en) * 2000-12-07 2011-06-22 Novartis Vaccines and Diagnostics, Inc. Endogenous retroviruses up-regulated in prostate cancer
WO2002055685A2 (en) * 2000-12-11 2002-07-18 Lexicon Genetics Incorporated Novel human kinase and polynucleotides encoding the same
DE10061931A1 (en) * 2000-12-13 2001-09-06 Marianne Kroepelin A new nucleic acid encoding M73791 HUMNOVGENE also known as HUMQM and human RPL10 is involved in tumor suppression and useful to diagnose and treat cancer
WO2002057460A2 (en) 2000-12-20 2002-07-25 Bristol-Myers Squibb Company Polynucleotides encoding human phosphatases
US6949363B2 (en) 2000-12-22 2005-09-27 Brilstol-Myers Squibb Polynucleotides encoding novel human leucine-rich repeat containing protein expressed predominately in bone marrow, HLRRBM1
EP1357186A4 (en) * 2000-12-28 2005-01-26 Takeda Pharmaceutical Novel proteins and dnas thereof
WO2002053748A1 (en) * 2001-01-02 2002-07-11 Bayer Aktiengesellschaft Regulation of human 3-ss-hydroxysteroid dehydrogenase-isomerase
GB0100750D0 (en) * 2001-01-11 2001-02-21 Inpharmatica Ltd Novel proteins
US6605710B2 (en) * 2001-01-11 2003-08-12 Board Of Trustees Of Michigan State University Gene whose expression promotes differentiation of myeloid progenitor cells into neutrophils and/or monocytes/macrophages
CA2434677A1 (en) * 2001-01-12 2002-10-10 Incyte Genomics, Inc. Molecules for diagnostics and therapeutics
AU2002245258A1 (en) * 2001-01-12 2002-07-24 Exelixis, Inc. Modulating insulin receptor signaling
GB2375110A (en) * 2001-01-30 2002-11-06 Aeomica Inc Human LCCL_domain containing peptides
US7041643B2 (en) 2001-01-31 2006-05-09 Millennium Pharmaceuticals, Inc. Molecules of the PYRIN/NBS/LRR protein family and uses thereof
US7160695B2 (en) 2001-01-31 2007-01-09 Wyeth Molecules of the PYRIN/NBS/LRR protein family and uses thereof
WO2002063013A2 (en) * 2001-02-02 2002-08-15 Mount Sinai Hospital Human acid phosphatase gene
US20030166041A1 (en) * 2001-02-08 2003-09-04 Hillman Jennifer L. TIMM8b-related protein
US7601825B2 (en) 2001-03-05 2009-10-13 Agensys, Inc. Nucleic acid and corresponding protein entitled 121P1F1 useful in treatment and detection of cancer
US7081516B2 (en) 2002-08-26 2006-07-25 Case Western Reserve University Methods for categorizing patients
US7118912B2 (en) 2002-08-26 2006-10-10 Case Western Reserve University Methods and compositions for categorizing patients
US20060035237A1 (en) 2002-08-26 2006-02-16 Markowitz Sanford D Methods and compositions for categorizing patients
US6924358B2 (en) 2001-03-05 2005-08-02 Agensys, Inc. 121P1F1: a tissue specific protein highly expressed in various cancers
EP1370585A2 (en) * 2001-03-05 2003-12-17 Aventis Pharma S.A. Nucleic acids of the human abcc12 gene, vectors containing such nucleic acids and uses thereof
AU2002252266B2 (en) 2001-03-08 2007-03-29 Immunex Corporation Human serpin polypeptides
US8647826B2 (en) 2001-03-14 2014-02-11 Agensys, Inc. Nucleic acid and corresponding protein entitled 125P5C8 useful in treatment and detection of cancer
US7271240B2 (en) 2001-03-14 2007-09-18 Agensys, Inc. 125P5C8: a tissue specific protein highly expressed in various cancers
WO2002074906A2 (en) * 2001-03-16 2002-09-26 Eli Lilly And Company Lp mammalian proteins; related reagents
US6551809B2 (en) * 2001-03-20 2003-04-22 Applera Corporation Isolated human phosphatase proteins, nucleic acid molecules encoding human phophatase proteins, and uses thereof
WO2002074981A2 (en) 2001-03-21 2002-09-26 Isis Innovation Ltd. Assays, methods and means relating to hypoxia inducible factor (hif) hydroxylase
EP1370580A2 (en) * 2001-03-23 2003-12-17 Universität Zürich A new essential downstream component of the wingless signalling pathway
AU2002242729A1 (en) * 2001-03-23 2002-10-08 Bayer Aktiengesellschaft Human dual specificity protein phosphatase 7-like protein
NZ527971A (en) * 2001-03-27 2006-03-31 Dendreon Corp Nucleic acid molecules encoding a transmembrane serine protease 9, the encoded polypeptides and methods based thereon
JPWO2002081515A1 (en) * 2001-04-03 2004-07-29 協和醗酵工業株式会社 Insulin-like growth factor binding protein
WO2002088303A2 (en) 2001-04-03 2002-11-07 Bristol-Myers Squibb Company Polynucleotide encoding a novel cysteine protease of the calpain superfamily, can-12, and variants thereof
CA2443123A1 (en) 2001-04-10 2002-10-24 Agensys, Inc. Nuleic acids and corresponding proteins useful in the detection and treatment of various cancers
AU2002258626B2 (en) 2001-04-10 2007-01-18 Agensys, Inc. Nucleid acid and corresponding protein entitled 158P3D2 useful in treatment and detection of cancer
US20030191073A1 (en) 2001-11-07 2003-10-09 Challita-Eid Pia M. Nucleic acid and corresponding protein entitled 161P2F10B useful in treatment and detection of cancer
WO2002083919A2 (en) 2001-04-10 2002-10-24 Agensys, Inc. Nucleic acid and corresponding protein entitled 184p1e2 useful in treatment and detection of cancer
CA2443617C (en) * 2001-04-17 2013-12-10 The Board Of Trustees Of The University Of Arkansas Repeat sequences of the ca125 gene and their use for diagnostic and therapeutic interventions
US7309760B2 (en) * 2001-04-17 2007-12-18 The Board Of Trustees Of The University Of Arkansas Repeat sequences of the CA125 gene and their use for diagnostic and therapeutic interventions
CA2444504A1 (en) * 2001-04-26 2002-11-07 Pe Corporation (Ny) Isolated human secreted proteins, nucleic acid molecules encoding human secreted proteins, and uses thereof
US7682607B2 (en) 2001-05-01 2010-03-23 The Regents Of The University Of California Wnt and frizzled receptors as targets for immunotherapy in head and neck squamous cell carcinomas
US7713526B2 (en) 2001-05-01 2010-05-11 The Regents Of The University Of California Wnt and frizzled receptors as targets for immunotherapy in head and neck squamous cell carcinomas
MXPA03010069A (en) 2001-05-03 2004-04-02 Childrens Medical Center Sperm-specific cation channel, and uses therefor.
US7217785B2 (en) * 2001-05-09 2007-05-15 The Regents Of The University Of California Cysteine-containing peptides having antioxidant properties
WO2002092798A2 (en) * 2001-05-11 2002-11-21 Bayer Healthcare Ag Regulation of human phosphatidic acid phosphatase type 2c-like protein
US7304034B2 (en) 2001-05-15 2007-12-04 The Feinstein Institute For Medical Research Use of HMGB fragments as anti-inflammatory agents
WO2002092004A2 (en) * 2001-05-15 2002-11-21 North Shore-Long Island Jewish Research Institute Use of hmg fragment as anti-inflammatory agents
US7220723B2 (en) 2001-05-15 2007-05-22 The Feinstein Institute For Medical Research Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents
US7452705B2 (en) 2001-05-22 2008-11-18 The University Of Chicago N4 virion single-stranded DNA dependent RNA polymerase
US7157558B2 (en) 2001-06-01 2007-01-02 Genentech, Inc. Polypeptide encoded by a polynucleotide overexpresses in tumors
ES2282444T3 (en) * 2001-06-05 2007-10-16 Auckland Uniservices Limited METHOD AND COMPOSITIONS TO EVALUATE THE FUNCTION AND DISORDERS PULMO NARES.
EP1402051A4 (en) * 2001-06-05 2005-08-17 Exelixis Inc Lces as modifiers of the p53 pathway and methods of use
JPWO2003008450A1 (en) * 2001-06-12 2004-11-11 伊東　恭悟 Tumor antigen
US20030009024A1 (en) * 2001-06-13 2003-01-09 Millennium Pharmaceuticals, Inc. 46584, a human transporter family member and uses therefor
US20030027301A1 (en) * 2001-06-14 2003-02-06 Yi Hu Novel human transporter proteins and polynucleotides encoding the same
US20030143668A1 (en) * 2001-06-18 2003-07-31 National Institute Of Advanced Industrial Guanosine triphosphate-binding protein coupled receptors
ITMI20011465A1 (en) 2001-07-10 2003-01-10 Novuspharma Spa GENE WITH ONCOSUPPRESSIVE ACTIVITY
WO2003006688A2 (en) * 2001-07-13 2003-01-23 University Of Aarhus Methods for diagnosis and treatment of diseases associated with altered expression of gnas
US20040210042A1 (en) * 2001-07-19 2004-10-21 Tsuchida Jun-Ichi Polypeptides relating to signal transfer of advanced glycation end product receptor
JP2003024080A (en) * 2001-07-19 2003-01-28 Univ Tokyo Protein inducing p53-dependent apoptosis and method for screening apoptosis controlling agent
WO2003010198A1 (en) * 2001-07-26 2003-02-06 Kenton Srl Identification of specific tumour antigens by selection of cdna libraries with sera and use of said antigens in diagnostic techniques
US7125701B2 (en) 2001-07-27 2006-10-24 Wyeth Aggrecanase molecules
US6887687B2 (en) * 2001-07-30 2005-05-03 Immunex Corporation Nucleic acids encoding human ataxin-1-like polypeptide IMX97018
FR2828209A1 (en) * 2001-08-01 2003-02-07 Cytomics Systems New nucleic acid encoding HECT-domain polypeptides, useful e.g. for treatment of cancer or inflammation, also new proteins, antibodies and modulators
JP2003135063A (en) * 2001-08-24 2003-05-13 Chiba Prefecture New gene nedl-1
EP1428882A4 (en) * 2001-08-24 2005-05-25 Hisamitsu Pharmaceutical Co Nucleic acids showing difference in expression between hepatoblastoma anc normal liver
EP1499350A4 (en) 2001-08-31 2006-02-08 Agensys Inc Nucleic acid and corresponding protein entitled 205p1b5 useful in treatment and detection of cancer
AU2002336446B2 (en) 2001-09-06 2008-03-06 Agensys, Inc. Nucleic acid and corresponding protein entitled STEAP-1 useful in treatment and detection of cancer
US7494646B2 (en) 2001-09-06 2009-02-24 Agensys, Inc. Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
EP2325335A3 (en) * 2001-09-14 2012-01-25 Clinical Genomics Pty. Ltd Nucleic acid markers for use in determining predisposition to neoplasm and/or adenoma
US20050222070A1 (en) 2002-05-29 2005-10-06 Develogen Aktiengesellschaft Fuer Entwicklungsbiologische Forschung Pancreas-specific proteins
JP2005504534A (en) 2001-09-19 2005-02-17 アメリカ合衆国政府 Transductin-1 and transductin-2 and application to hereditary hearing impairment
JP2003093056A (en) * 2001-09-26 2003-04-02 Japan Science & Technology Corp ENZYME PHOSPHORYLATING Ser46 of p53
US20030108928A1 (en) * 2001-10-09 2003-06-12 Millennium Pharmaceuticals, Inc. MID 241 receptor, a novel G-protein coupled receptor
MXPA04003635A (en) * 2001-10-16 2004-07-30 Autogen Res Pty Ltd Differentially expressed genes associated with obesity and type 2 diabetes.
US20030100034A1 (en) * 2001-10-16 2003-05-29 Millennium Pharmaceuticals, Inc. 9136, a human aldehyde dehydrogenase family member and uses therefor
DE10152598A1 (en) * 2001-10-19 2003-05-22 Schering Ag ARL-2-for fertility control
US8729248B2 (en) 2001-10-22 2014-05-20 Children's Medical Center Corporation Sperm-specific cation channel, CATSPER2, and uses therefor
AU2002364939A1 (en) * 2001-10-22 2003-07-09 Board Of Regents, The University Of Texas System Sperm-specific cation channel, catsper2, and uses therefor
WO2003038130A2 (en) * 2001-10-31 2003-05-08 Pfizer Products Inc. Therapeutics and diagnostics for disorders of erythropoiesis
DE10153259A1 (en) * 2001-10-31 2003-05-22 Osram Opto Semiconductors Gmbh Optoelectronic component
AU2002359331A1 (en) * 2001-10-31 2003-06-10 Millennium Pharmaceuticals, Inc. Methods and compositions for the treatment and diagnosis of cellular proliferative disorders using 32222
WO2003040340A2 (en) 2001-11-07 2003-05-15 Agensys, Inc. Nucleic acid and corresponding protein entitled 161p2f10b useful in treatment and detection of cancer
JP2005508178A (en) * 2001-11-08 2005-03-31 デヴェロゲン アクチエンゲゼルシャフト フュア エントヴィックルングスビオローギッシェ フォルシュング Men protein, GST2, Rab-RP1, Csp, F-box protein Lilina / FBL7, ABC50, coronin, Sec61α, or VhaPPA1-1 or homologous protein involved in regulation of energy homeostasis
US7816087B2 (en) * 2001-11-14 2010-10-19 The United States Of America As Represented By The Department Of Health And Human Services Gene expressed in prostate cancer and methods of use
US20030100016A1 (en) * 2001-11-23 2003-05-29 George Jackowski Complement C3 precursor biopolymer markers predictive of Alzheimers disease
US7074576B2 (en) * 2001-11-23 2006-07-11 Syn X Pharma, Inc. Protein biopolymer markers indicative of alzheimer's disease
ES2605445T3 (en) 2001-11-26 2017-03-14 Hivih Protein-protein interactions in the human immunodeficiency virus
WO2003046165A1 (en) * 2001-11-26 2003-06-05 Bayer Healthcare Ag Regulation of human aldose reductase-like protein
AU2002360460A1 (en) * 2001-12-03 2003-06-17 Nuvelo, Inc. Methods and materials relating to novel polypeptides and polynucleotides
ATE309542T1 (en) * 2001-12-04 2005-11-15 Brahms Ag USE OF GLYCINE N-ACYL TRANSFERASE (GNAT) FOR THE DIAGNOSIS OF INFLAMMATORY DISEASES AND SEPSIS
US20070037147A1 (en) * 2001-12-07 2007-02-15 Pablo Garcia Endogenous retrovirus polypeptides linked to oncogenic transformation
US20060275747A1 (en) * 2001-12-07 2006-12-07 Hardy Stephen F Endogenous retrovirus up-regulated in prostate cancer
EP1456381A1 (en) * 2001-12-10 2004-09-15 Amersham plc Human prostate cancer candidate protein 1
EP1463818A2 (en) * 2001-12-14 2004-10-06 Incyte Genomics, Inc. Transporters and ion channels
AU2002357850A1 (en) * 2001-12-14 2003-06-30 Incyte Genomics, Inc. Neurotransmission-associated proteins
JP2005527191A (en) * 2001-12-18 2005-09-15 アンドキューブ ソシエタ パー アクシオン シンプリフィー Novel cell death-related proteins and THAP1 and PAR4 pathways in controlling apoptosis
US7858297B2 (en) * 2001-12-18 2010-12-28 Centre National De La Recherche Scientifique Cnrs Chemokine-binding protein and methods of use
JP3837524B2 (en) 2001-12-19 2006-10-25 国立大学法人 長崎大学 Nucleic acid, probe comprising the nucleic acid, and screening method using the probe
JP2003245084A (en) 2001-12-20 2003-09-02 Morinaga Milk Ind Co Ltd New gene useful for diagnosis and treatment of aplasia of corpus callosum and aspermatogenesis and use thereof
AU2002357347A1 (en) * 2001-12-21 2003-07-30 Ramot At Tel Aviv University Ltd. Chromatin remodeling protein as a marker expressed by stromal progenitor cells
GB0130720D0 (en) * 2001-12-21 2002-02-06 Serono Internat S A Proteins
US20050112618A1 (en) * 2001-12-21 2005-05-26 Fagan Richard J. Secreted protein
AU2003235632A1 (en) * 2002-01-16 2003-07-30 Bayer Aktiengesellschaft Regulation of human fatty acid coa ligase-like amp-binding enzyme
WO2003060110A2 (en) * 2002-01-16 2003-07-24 Bayer Healthcare Ag Regulation of human fatty acid coa ligase-like amp-binding enzyme
WO2003062453A2 (en) * 2002-01-23 2003-07-31 Mayo Foundation For Medical Education And Research Polycystic kidney disease nucleic acids and proteins
JPWO2003062429A1 (en) * 2002-01-23 2005-05-26 山之内製薬株式会社 New serine protease
GB0202149D0 (en) * 2002-01-30 2002-03-20 Univ Edinburgh Pluripotency determining factors and uses thereof
AU2003215548A1 (en) * 2002-02-01 2003-09-02 Bayer Healthcare Ag Regulation of human hematopoietin receptor-like protein
CA2477159A1 (en) * 2002-02-20 2003-08-28 Invitrogen Corporation Highly homogeneous molecular markers for electrophoresis
EP1338606A1 (en) * 2002-02-22 2003-08-27 Magnus Von Knebel Doeberitz Nucleic Acid encoding an HERV-H polypeptide for diagnosing colorectal cancer
GB2388113A (en) * 2002-03-06 2003-11-05 Oxford Glycosciences B-cell malignancy-associated protein
JP2003259872A (en) * 2002-03-07 2003-09-16 Japan Science & Technology Corp Human esophageal carcinoma antigenic peptide and method for diagnosing esophageal carcinoma
EP1489180A1 (en) * 2002-03-07 2004-12-22 BF Research Institute, Inc. P18abeta rp gene and p18abeta rp protein, novel gene/protein (p60trp) interacting therewith to inhibit cell death and cell death promoter
WO2003076622A1 (en) * 2002-03-08 2003-09-18 Eisai Co., Ltd. PRESYNAPTIC PROTEIN p120
DE10211088A1 (en) * 2002-03-13 2003-09-25 Ugur Sahin Gene products differentially expressed in tumors and their use
AU2012216265B2 (en) * 2002-03-13 2015-01-22 Biontech Ag Genetic products differentially expressed in tumors and use thereof
AU2003220920B2 (en) * 2002-03-14 2008-11-06 National Institute Of Advanced Industrial Science And Technology Novel N-Acetylglucosamine transferase, nucleic acid encoding the same and use thereof in diagnosing cancer and / or tumor
US7202056B2 (en) 2002-03-28 2007-04-10 Bristol-Myers Squibb Company Polynucleotides encoding a human cell surface protein with immunoglobulin folds, BGS-19
US20040002593A1 (en) * 2002-04-04 2004-01-01 Reed John C. PAAD domain-containing polypeptides, encoding nucleic acids, and methods of use
US7544767B2 (en) * 2002-04-05 2009-06-09 Burnham Institute For Medical Research HMGN2 peptides and related molecules that selectively home to tumor blood vessels and tumor cells
WO2003087300A2 (en) * 2002-04-05 2003-10-23 Incyte Corporation Secreted proteins
US20060088835A1 (en) * 2002-04-05 2006-04-27 Pickard Benjamin S Schizophrenia associated genes
AU2003234717A1 (en) 2002-04-12 2003-10-27 Bristol-Myers Squibb Company Novel polynucleotides encoding the human citron kinase polypeptide, bmsnkc 0020/0021
EP1501533A4 (en) 2002-04-22 2007-10-31 Univ Leland Stanford Junior Peptide inhibitors of protein kinase c-gamma for pain management
WO2003091402A2 (en) * 2002-04-23 2003-11-06 University Of Georgia Research Foundation, Inc. N-ACETYLGLUCOSAMINYLTRANSFERASE Vb CODING SEQUENCE, RECOMBINANT CELLS AND METHODS
EP1497460A1 (en) * 2002-04-26 2005-01-19 EVOTEC Neurosciences GmbH Diagnostic and therapeutic use of ensadin-0138 gene and protein for neurodegenerative diseases
WO2004044125A2 (en) * 2002-05-15 2004-05-27 Incyte Corporation Vesicle-associated proteins
ATE414789T1 (en) * 2002-05-21 2008-12-15 Mtm Lab Ag MARKER FOR LUNG TUMORS
EP2275118A3 (en) * 2002-05-29 2011-10-19 DeveloGen Aktiengesellschaft Pancreas-specific proteins
DK1513934T3 (en) * 2002-06-06 2011-05-02 Oncotherapy Science Inc Genes and polypeptides related to human colon cancer diseases
US7339028B2 (en) * 2002-06-06 2008-03-04 The Trustees Of Columbia University In The City Of New York Mahoganoid polypeptides, and related compositions and methods
US20050164201A1 (en) * 2002-06-10 2005-07-28 Harvey Diane M. Isolated nucleic acid molecule encoding a novel centromere-associated motor protein, and uses therof
ATE545651T1 (en) * 2002-06-13 2012-03-15 Novartis Vaccines & Diagnostic VECTORS FOR EXPRESSING HML-2 POLYPEPTIDES
AU2003238032A1 (en) * 2002-06-24 2004-01-06 Bayer Healthcare Ag Regulation of human growth hormone-releasing hormone receptor
FR2841261B1 (en) * 2002-06-25 2004-08-27 Univ Pasteur COMPOSITIONS AND METHODS FOR DETECTING PATHOLOGIES AFFECTING NEUROMUSCULAR TRANSMISSION
WO2004001017A2 (en) * 2002-06-25 2003-12-31 Tao Biosciences, Llc Methods for identifying antimicrobial agents, the agents identified therewith and methods of using same
WO2004005541A1 (en) * 2002-07-09 2004-01-15 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw Diagnostic tests for the detection of peripheral neuropathy
AU2003253930A1 (en) * 2002-07-11 2004-02-02 Seattle Genetics, Inc. Sga-72m, a cancer associated antigen, and uses thereof
EP1382613A1 (en) 2002-07-16 2004-01-21 Sumitomo Chemical Company, Limited Novel G protein, polynucleotide encoding the same and utilization thereof
EP1556079A2 (en) 2002-07-16 2005-07-27 Emory University Regulatory protein for nox enzymes
GB0216661D0 (en) * 2002-07-17 2002-08-28 Ares Trading Sa Protein
US20040132058A1 (en) * 2002-07-19 2004-07-08 Schering Corporation NPC1L1 (NPC3) and methods of use thereof
US7135556B2 (en) 2002-07-19 2006-11-14 Schering Corporation NPC1L1 (NPC3) and methods of use thereof
US20050019404A1 (en) * 2003-06-30 2005-01-27 Hsing-Wen Sung Drug-eluting biodegradable stent
US20050163821A1 (en) * 2002-08-02 2005-07-28 Hsing-Wen Sung Drug-eluting Biodegradable Stent and Delivery Means
WO2004015066A2 (en) 2002-08-07 2004-02-19 Children's Medical Center Corporation Sperm-specific cation channel, catsper-4, and uses therefor
AU2003258056A1 (en) 2002-08-07 2004-02-25 Children's Medical Center Corporation Sperm-specific cation channel, catsper-3, and uses therefor
US7408048B2 (en) 2002-08-09 2008-08-05 Melbourne Health Mammalian grainyhead transcription factors
WO2004089282A2 (en) * 2002-08-09 2004-10-21 Curagen Corporation Therapeutic polypeptides, nucleic acids encoding same, and methods of use
US20040081653A1 (en) 2002-08-16 2004-04-29 Raitano Arthur B. Nucleic acids and corresponding proteins entitled 251P5G2 useful in treatment and detection of cancer
AU2003282785A1 (en) * 2002-08-26 2004-03-11 Case Western Reserve University Methods for treating patients and identifying therapeutics
DE10242146A1 (en) 2002-09-04 2004-03-18 Eberhard-Karls-Universität Tübingen Universitätsklinikum Antibodies for the identification and / or isolation of hematopoietic stem cells
CA2497337A1 (en) * 2002-09-11 2004-03-25 Genentech, Inc. Novel composition and methods for the treatment of psoriasis
WO2004024914A1 (en) * 2002-09-13 2004-03-25 Sankyo Company, Limited 2’,5’-oligoadenylate phosphodiesterase
EP1398372A1 (en) * 2002-09-13 2004-03-17 Universitätsklinikum Charité an der Humboldt- Universität zu Berlin Lipid phosphate phosphatases and uses thereof for treating neuronal diseases
US6892925B2 (en) * 2002-09-18 2005-05-17 International Business Machines Corporation Solder hierarchy for lead free solder joint
CA2497937A1 (en) * 2002-09-19 2004-04-01 Tanox, Inc. Nuclear factor of activated t cells receptor
JP2006500074A (en) * 2002-09-27 2006-01-05 オリディス・ビオメド・フォルシュングス−ウント・エントヴィックルングス・ゲーエムベーハー Polypeptides and nucleic acids encoding them and their use for prevention, diagnosis or treatment of liver damage and epithelial cancer
TW200413725A (en) * 2002-09-30 2004-08-01 Oncotherapy Science Inc Method for diagnosing non-small cell lung cancers
WO2004033636A2 (en) * 2002-10-04 2004-04-22 Incyte Corporation Protein modification and maintenance molecules
US20060057147A1 (en) * 2002-10-04 2006-03-16 Mitsubishi Pharma Corporation Antibody recognizing antibody
US7122361B2 (en) 2002-10-10 2006-10-17 Wyeth Compositions employing a novel human kinase
GB0224116D0 (en) * 2002-10-16 2002-11-27 Ares Trading Sa Proteins
AU2003279312A1 (en) * 2002-10-24 2004-05-13 Evotec Neurosciences Gmbh Diagnostic and therapeutic use of ensadin-0289 gene and protein for neurodegenerative diseases
WO2004038026A2 (en) * 2002-10-24 2004-05-06 Wyeth Calcineurin-like human phosphoesterase
AU2003275713A1 (en) * 2002-10-29 2004-05-25 Takeda Pharmaceutical Company Limited Use of sglt homolog
US7537914B1 (en) * 2002-11-04 2009-05-26 Florida State University Research Foundation, Inc. Nucleic acid and allergenic polypeptides encoded thereby in cashew nuts (Anacardium occidentale)
WO2004044205A1 (en) * 2002-11-11 2004-05-27 Korea Chungang Educational Foundation Plant seed-specific expression promoter derived from sesame and seed-specific expression vector comprising the promoter
US7405289B2 (en) * 2002-11-13 2008-07-29 Metabolex, Inc. Pancreatic islet transcription factor and uses thereof
WO2004043403A2 (en) * 2002-11-13 2004-05-27 The Uab Research Foundation Synthetic single domain polypeptides mimicking apolipoprotein e and methods of use
BR0316476A (en) * 2002-11-21 2005-10-11 Wyeth Corp Composition and process for treating lupus nephritis
DE10254601A1 (en) 2002-11-22 2004-06-03 Ganymed Pharmaceuticals Ag Gene products differentially expressed in tumors and their use
NZ540701A (en) 2002-11-26 2007-07-27 Univ Tennessee Res Foundation Streptococcus uberis adhesion molecule
AU2003290664A1 (en) 2002-11-27 2004-06-23 Wei Liu Compositions, organisms and methodologies employing a novel human kinase
US20070016967A1 (en) * 2002-12-04 2007-01-18 Applied Research Systems Ars Holding N.V. Novel IFNgamma-like polypeptides
US6854636B2 (en) * 2002-12-06 2005-02-15 International Business Machines Corporation Structure and method for lead free solder electronic package interconnections
AU2003290066A1 (en) * 2002-12-18 2004-07-09 Novartis Ag Anktm1, a cold-activated trp-like channel expressed in nociceptive neurons
US20050049214A1 (en) * 2003-01-15 2005-03-03 Chiron Corporation Inhibition of E3-ubiquitin ligase HAKAI for treatment of proliferative disorders
AU2007231823B2 (en) * 2003-01-24 2011-07-21 Agensys, Inc. Nucleic acids and corresponding proteins entitled 254P1D6B useful in treatment and detection of cancer
EP1590437A4 (en) 2003-01-24 2008-06-18 Agensys Inc Nucleic acids and corresponding proteins entitled 254p1d6b useful in treatment and detection of cancer
US7304036B2 (en) * 2003-01-28 2007-12-04 Microbia, Inc. Methods and compositions for the treatment of gastrointestinal disorders
US20060160087A1 (en) * 2003-01-31 2006-07-20 Mcgrath Michael Monitoring and treatment of amyotrophic lateral sclerosis
JP2008500009A (en) 2003-03-03 2008-01-10 ジェネンテック・インコーポレーテッド Compositions and methods for the treatment of systemic lupus erythematosus
EP1923400A1 (en) * 2003-03-03 2008-05-21 Genentech, Inc. Compositions and methods for the treatment of systemic lupus erythematosis
US7521534B1 (en) * 2003-03-03 2009-04-21 The University Board Of Regents Of Texas System IKK gamma gene products and methods for making and using same
JP2006521810A (en) * 2003-03-11 2006-09-28 ジェネンテック・インコーポレーテッド Novel compositions and methods for the treatment of immune related diseases
US20080081841A1 (en) * 2003-03-20 2008-04-03 Badache Ali Materials and Methods for Modulating Cell Motility
EP1464651A1 (en) * 2003-04-03 2004-10-06 Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts Dystrophin-related protein (Drop1), a marker for carcinomas
EP1651667B1 (en) * 2003-04-04 2012-03-28 Centre National De La Recherche Scientifique Protein with fusogenic activity, nucleic acid sequences encoding said protein and pharmaceutical compositions comprising the same
WO2004092213A1 (en) * 2003-04-08 2004-10-28 The Government Of The United States Of America As Represented By The Secretary, Department Of Healthand Human Services Gene expressed in prostate cancer, methods and use thereof
WO2004094651A2 (en) * 2003-04-18 2004-11-04 Five Prime Therapeutics, Inc. Novel human polypeptides encoded by polynucleotides
US20050032695A1 (en) * 2003-05-30 2005-02-10 Aventis Pharma Deutschland Gmbh Method for alleviating pain using protein associated with MYC and related compounds, and assays for identifying such compounds
US7696169B2 (en) 2003-06-06 2010-04-13 The Feinstein Institute For Medical Research Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents
FR2843753A1 (en) * 2003-06-20 2004-02-27 Gene Signal Antisense nucleic molecule useful as inhibitor of angiogenesis in the treatment of angiogenic disorders, e.g., rheumatoid arthritis, atherosclerosis and endometriosis
JP2007527699A (en) * 2003-06-26 2007-10-04 エグゾニ・テラピューティック・ソシエテ・アノニム Prostate specific genes and their use as targets for prostate cancer treatment and diagnosis
FR2857098B1 (en) * 2003-07-04 2006-05-05 Inst Nat Sante Rech Med METHOD FOR THE EVIDENCE OF A MOLECULAR EVENT IN A CELL USING FLUORESCENT MARKER PROTEINS
GB0315827D0 (en) * 2003-07-05 2003-08-13 Imp College Innovations Ltd Methods
WO2005049791A2 (en) * 2003-07-14 2005-06-02 The Uab Research Foundation Identification of reagents for the diagnosis and study of francisella
EP1507004A1 (en) * 2003-08-14 2005-02-16 DKFZ Deutsches Krebsforschungszentrum Method to inhibit the propagation of an undesired cell population
WO2005019255A1 (en) 2003-08-25 2005-03-03 Pieris Proteolab Ag Muteins of tear lipocalin
EP1660651A2 (en) * 2003-09-04 2006-05-31 Applied Research Systems ARS Holding N.V. Ubp8rp polypeptides and their use in the treatment of psoriasis
AU2004269927B2 (en) 2003-09-08 2009-09-17 Merck Serono Sa Treatment of fibrotic disease
DE10341812A1 (en) 2003-09-10 2005-04-07 Ganymed Pharmaceuticals Ag Differentially expressed in tumors gene products and their use
EP1668035A2 (en) 2003-09-11 2006-06-14 Critical Therapeutics, Inc. Monoclonal antibodies against hmgb1
JP4634302B2 (en) * 2003-09-30 2011-02-16 第一三共株式会社 Tetrahydrofolate synthase gene
US20050136451A1 (en) * 2003-10-06 2005-06-23 Li Yan Hypoxia responsive human CNGH 0002 genes and polypeptides
US7431915B2 (en) 2003-10-31 2008-10-07 The Regents Of The University Of California Peptides whose uptake by cells is controllable
US7985401B2 (en) 2003-10-31 2011-07-26 The Regents Of The University Of California Peptides whose uptake by cells is controllable
CN100434437C (en) * 2003-11-19 2008-11-19 康哲医药研究(深圳)有限公司 Biological active peptides comprising isoleucyl-valyl-threonyl-asparaginyl-threonyl-threonine
US20050255560A1 (en) * 2003-11-21 2005-11-17 Zeren Gao Ztnf11, a tumor necrosis factor
US8853363B2 (en) 2003-11-26 2014-10-07 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Substance binding human IgG Fc receptor IIb (FcγRIIb)
EP1711609A1 (en) * 2003-12-15 2006-10-18 Genesis Research & Development Corporation Limited Polynucleotides and polypeptides isolated from lactobacillus rhamnosus hn001 materials incorporating them and methods for using them
GB0329958D0 (en) * 2003-12-24 2004-01-28 Univ Manchester Treatment of viral infections
EP1723414A4 (en) 2004-01-16 2008-03-26 Merck & Co Inc Npc1l1 (npc3) and methods of identifying ligands thereof
WO2005073725A1 (en) 2004-01-28 2005-08-11 Exelixis, Inc Man2as as modifiers of the igfr pathway and methods of use
US7148192B2 (en) * 2004-01-29 2006-12-12 Ebwe Pharma Ges. M.H. Nfg.Kg Neuroprotective dietary supplement
US20050255530A1 (en) * 2004-02-06 2005-11-17 Keefer Carol L Identification and isolation of pluripotency determining factors
GB0403142D0 (en) * 2004-02-12 2004-03-17 Ares Trading Sa Protein
US20050186577A1 (en) 2004-02-20 2005-08-25 Yixin Wang Breast cancer prognostics
CA2560066A1 (en) 2004-03-01 2005-09-15 The Cbr Institute For Biomedical Research, Inc. Natural igm antibodies and inhibitors thereof
US7166433B2 (en) * 2004-03-03 2007-01-23 The United States Of America As Represented By The Department Of Health And Human Services Transductin-1 and transductin-2 and applications to hereditary deafness
WO2005086674A2 (en) * 2004-03-04 2005-09-22 Uab Research Foundation Brhf1 as a cancer diagnostic marker
WO2005090994A2 (en) * 2004-03-24 2005-09-29 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with protein kinase, cgmp-dependent, type i (prkg1)
WO2005098440A2 (en) * 2004-03-26 2005-10-20 Immusol, Inc. Methods for identifying agents useful for the treatment of neurodegenerative diseases
EP1733743A4 (en) 2004-04-09 2007-06-27 Takeda Pharmaceutical Preventives/remedies for cancer
WO2005108563A2 (en) * 2004-04-19 2005-11-17 University Of Chicago Peptidoglycan-hydrolyzing protein encoded by bacteriophage n4
EA014870B1 (en) 2004-04-22 2011-02-28 Эдженсис, Инк. Antibodies that bind to steap-1 proteins
CA2810292C (en) * 2004-05-14 2015-09-29 Euroscreen S.A. Ligand for g-protein coupled receptor fprl2 and uses thereof
DE102004024617A1 (en) 2004-05-18 2005-12-29 Ganymed Pharmaceuticals Ag Differentially expressed in tumors gene products and their use
JP4649575B2 (en) * 2004-05-19 2011-03-09 財団法人ヒューマンサイエンス振興財団 Diagnosis of novel mucin genes and mucosal-related diseases
WO2005114200A1 (en) * 2004-05-21 2005-12-01 Bayer Healthcare Ag Diagnostics and therapeutics for diseases associated with g protein-coupled receptor kinase 7 (grk7)
EP2031063B1 (en) 2004-06-18 2013-11-06 Duke University Modulators of odorant receptors
EP1765857A2 (en) * 2004-07-02 2007-03-28 Metanomics GmbH Process for the production of fine chemicals
US20070264277A1 (en) * 2004-07-22 2007-11-15 Dirk Behrens Compositions and Methods of Use for Mgd-Csf in Disease Treatment
WO2006022689A1 (en) * 2004-08-06 2006-03-02 Applera Corporation Method and compositions for treating diseases targeting cd51
WO2006023598A2 (en) 2004-08-19 2006-03-02 University Of Maryland, Baltimore Prostate-specific antigen-derived mhc class ii-restricted peptides and their use in vaccines to treat or prevent prostate cancer
US20110177079A1 (en) * 2004-09-08 2011-07-21 Ludwig Institute For Cancer Research Cancer-testis antigens
DE602005023329D1 (en) 2004-09-24 2010-10-14 Oncotherapy Science Inc METHOD FOR DIAGNOSIS OF NON-SMALL CELL LUNG CARCINOMAS USING URLC8'S TRNA DIHYDROURIDINE SYNTHASE ACTIVITY
US9944713B2 (en) * 2004-11-24 2018-04-17 Medicinal Bioconvergence Research Center Antibody specific to the AIMP2-DX2
EP1836216B1 (en) * 2004-12-10 2021-05-05 DendroCyte BioTech Pty Ltd Binding partners of antibodies specific for dendritic cell antigens
DE102004059781A1 (en) * 2004-12-10 2006-06-22 Sanofi-Aventis Deutschland Gmbh Use of serum / glucocorticoid-regulated kinase
AU2005319382B2 (en) 2004-12-21 2011-04-07 Astrazeneca Ab Antibodies directed to angiopoietin-2 and uses thereof
WO2006090389A2 (en) 2005-02-24 2006-08-31 Compugen Ltd. Novel diagnostic markers, especially for in vivo imaging, and assays and methods of use thereof
US8350009B2 (en) 2005-03-31 2013-01-08 Agensys, Inc. Antibodies and related molecules that bind to 161P2F10B proteins
AU2006230563B8 (en) 2005-03-31 2010-06-17 Agensys, Inc. Antibodies and related molecules that bind to 161P2F10B proteins
WO2006111586A2 (en) * 2005-04-20 2006-10-26 Proyecto De Biomedicina Cima, S.L. Method for the in vitro determination of the degree of methylation of the line-1 promoter
CA2608158A1 (en) * 2005-05-19 2006-11-23 Synergenz Bioscience Limited Methods and compositions for assessment of pulmonary function and disorders
KR20080011292A (en) * 2005-05-19 2008-02-01 시너젠즈 바이오사이언스 리미티드 Methods for the assessment of risk of developing lung cancer using analysis of genetic polymorphisms
WO2006123943A1 (en) * 2005-05-20 2006-11-23 Synergenz Bioscience Limited Methods of analysis of polymorphisms and uses thereof
US8080632B2 (en) 2005-09-01 2011-12-20 The Feinstein Institute For Medical Research Peptide mimics of melanocyte stimulating hormone
WO2007035474A2 (en) * 2005-09-15 2007-03-29 Novomed Technologies, Inc. (Shanghai) Transdermal delivery peptides and method of use thereof
US7659252B2 (en) 2005-09-15 2010-02-09 Novomed Technologies, Inc. (Shanghai) Transdermal delivery peptides and method of use thereof
WO2007053803A2 (en) * 2005-10-31 2007-05-10 Centocor, Inc. Antagonist of teb4 and methods of use
EP1790664A1 (en) 2005-11-24 2007-05-30 Ganymed Pharmaceuticals AG Monoclonal antibodies against claudin-18 for treatment of cancer
US20070186295A1 (en) * 2006-01-25 2007-08-09 Daniel Chelsky TAT-036 and methods of assessing and treating cancer
US8207300B2 (en) * 2006-01-30 2012-06-26 Ludwig Institute For Cancer Research Ltd. CTSP cancer-testis antigens
JP2009525055A (en) * 2006-02-01 2009-07-09 ザ バーナム インスティテュート フォー メディカル リサーチ Zip code of lymphatic vessels in tumors and precancerous lesions
EP1991246B1 (en) * 2006-02-22 2013-09-11 Zhenglun Zhu Treatment of development-related disorders
US7910698B2 (en) 2006-02-24 2011-03-22 Schering Corporation NPC1L1 orthologues
AU2007224704B2 (en) * 2006-03-13 2012-12-06 Novovacs Holding B.V. Cancer vaccine
US7811787B2 (en) * 2006-04-25 2010-10-12 Bristol-Myers Squibb Company Polynucleotides encoding human SLAP-2 variant, hSLAP-2v3
JP5564249B2 (en) * 2006-06-23 2014-07-30 アレシア・バイオセラピューティクス・インコーポレーテッド Polynucleotide and polypeptide sequences involved in cancer
JP5339291B2 (en) 2006-08-10 2013-11-13 オンコセラピー・サイエンス株式会社 Breast cancer-related genes and polypeptides
CA3163418A1 (en) 2006-10-06 2008-05-22 Jeffrey S. Isenberg Prevention of tissue ischemia, related methods and compositions
RS53942B1 (en) 2006-10-27 2015-08-31 Genentech Inc. Antibodies and immunoconjugates and uses therefor
CN101611152B (en) * 2006-12-21 2013-10-16 克格诺西有限公司 Methods for modulating SET and uses thereof
WO2008114672A1 (en) * 2007-03-15 2008-09-25 Reverse Proteomics Research Institute Co., Ltd. Cancer-specific biomarker
WO2008121007A1 (en) * 2007-03-29 2008-10-09 Auckland Uniservices Limited Novel saratan polypeptides and polynucleotides and methods of use thereof
JP5219146B2 (en) * 2007-03-30 2013-06-26 国立大学法人 岡山大学 Novel SLC17 type transporter protein and its use in mammals
US20100249038A1 (en) * 2007-06-12 2010-09-30 Board Of Regents, University Of Texas System Antagonists of the receptor for advanced glycation end-products (rage)
FR2919616A1 (en) * 2007-08-02 2009-02-06 Ecole Norm Superieure Lyon INSULATORY POLYNUCLEOTIDES DERIVED FROM THE D4Z4 ELEMENT AND THEIR USES IN TRANSGENESIS
US8163874B2 (en) * 2007-08-06 2012-04-24 The United States Of America, As Represented By The Secretary Of The Navy Beta helical peptide structures stable in aqueous and non-aqueous media and methods for preparing same
WO2009019289A1 (en) * 2007-08-09 2009-02-12 Novartis Ag Thiopeptide precursor protein, gene encoding it and uses thereof
AU2008289441A1 (en) 2007-08-22 2009-02-26 Cytomx Therapeutics, Inc. Activatable binding polypeptides and methods of identification and use thereof
KR20100063719A (en) * 2007-08-24 2010-06-11 라모트 앳 텔-아비브 유니버시티 리미티드 Neuroprotection using nap-like and sal-like peptide mimetics
DK2682400T5 (en) 2007-08-28 2017-11-27 Uab Research Foundation Synthetic apolipoprotein E mimic polypeptides and methods of use
DE102007041657A1 (en) * 2007-09-03 2009-03-05 Protagen Ag Marker sequences for multiple sclerosis and their use
US8450279B2 (en) * 2007-09-04 2013-05-28 Procell Therapeutics Inc. Cell permeable Nm23 recombinant proteins, polynucleotides encoding the same, and anti-metastatic composition comprising the same
US9134314B2 (en) 2007-09-06 2015-09-15 Case Western Reserve University Methods for diagnosing and treating cancers
US8802631B2 (en) * 2007-09-17 2014-08-12 Ludwig Institute For Cancer Research Ltd. Peptides and methods for the treatment of gliomas and other cancers
CN101969987A (en) * 2007-09-20 2011-02-09 J·大卫格莱斯顿学会 Long interspersed nuclear element polypeptide compositions and methods of use thereof
GB0719367D0 (en) 2007-10-03 2007-11-14 Procarta Biosystems Ltd Transcription factor decoys, compositions and methods
AU2009242486B2 (en) * 2008-05-02 2013-10-10 Cellscript, Inc. RNA polyphosphatase compositions, kits, and uses thereof
WO2009140418A2 (en) * 2008-05-14 2009-11-19 Five Prime Therapeutics, Inc. Compositions and methods for treating arthritis and/or diseases involving cartilage degeneration
US9051574B2 (en) * 2008-06-03 2015-06-09 University Of Maryland, Baltimore Non-hemolytic ClyA for excretion of proteins
WO2009154573A1 (en) * 2008-06-19 2009-12-23 Agency For Science, Technology And Research Modulators of stat3 signalling
EP2324048A2 (en) * 2008-07-30 2011-05-25 Cosmix Therapeutics Llc Peptide therapeutics that bind vegf and methods of use thereof
EP2172477A1 (en) * 2008-10-06 2010-04-07 Atlas Antibodies AB Epitopes derived from SATB2 and uses thereof
US8326829B2 (en) * 2008-10-17 2012-12-04 Centurylink Intellectual Property Llc System and method for displaying publication dates for search results
US8874564B2 (en) * 2008-10-17 2014-10-28 Centurylink Intellectual Property Llc System and method for communicating search results to one or more other parties
US8156130B2 (en) 2008-10-17 2012-04-10 Embarq Holdings Company Llc System and method for collapsing search results
WO2010048125A2 (en) * 2008-10-22 2010-04-29 Trustees Of Dartmouth College Compositions and methods for inhibiting the interaction between cftr and cal
US8999919B2 (en) 2008-10-22 2015-04-07 Trustees Of Dartmouth College Compositions and methods for inhibiting the interaction between CFTR and CAL
US9333235B2 (en) 2008-10-22 2016-05-10 Trustees Of Dartmouth College Combination therapy and kit for the prevention and treatment of cystic fibrosis
US9421239B2 (en) 2008-10-22 2016-08-23 Trustees Of Dartmouth College Therapy and kit for the prevention and treatment of cystic fibrosis
EP2722400A3 (en) * 2008-10-29 2014-07-09 William Beaumont Hospital Methods of using biomarkers
US20110207667A1 (en) * 2008-10-30 2011-08-25 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Efficient expression of truncated human rnaset2 in e. coli
WO2010060186A1 (en) 2008-11-03 2010-06-03 Alethia Biotherapeutics Inc. Antibodies that specifically block the biological activity of a tumor antigen
US20110286924A1 (en) * 2008-12-09 2011-11-24 Alethia Biotherapeutics Inc Novel human endogenous retroviral erv3 variant and uses thereof in the diagnosing ovarian cancer
US20100189651A1 (en) 2009-01-12 2010-07-29 Cytomx Therapeutics, Llc Modified antibody compositions, methods of making and using thereof
RU2011138951A (en) * 2009-02-23 2013-03-27 Сайтомкс Терапьютикс, Инк. PROTEINS AND WAYS OF THEIR APPLICATION
JP5704722B2 (en) * 2009-02-24 2015-04-22 国立大学法人 宮崎大学 Cell adhesion inhibitor and use thereof
EP2403864B1 (en) 2009-02-27 2015-08-12 Atyr Pharma, Inc. Polypeptide structural motifs associated with cell signaling activity
ES2742251T3 (en) 2009-03-16 2020-02-13 Pangu Biopharma Ltd Compositions and methods comprising variants of histidyl tarn synthetase splicing that have non-canonical biological activities
CN105601725B (en) 2009-03-18 2019-08-09 肿瘤疗法科学股份有限公司 NEIL3 peptide and vaccine comprising it
CA2757289A1 (en) * 2009-03-31 2010-10-21 Atyr Pharma, Inc. Compositions and methods comprising aspartyl-trna synthetases having non-canonical biological activities
WO2010118324A2 (en) 2009-04-09 2010-10-14 Nuclea Biotechnologies, LLC Antibodies against fatty acid synthase
CA2767570C (en) 2009-07-13 2018-05-01 Universite De Montreal Mutated sumo isoforms and uses thereof
JP2012533560A (en) 2009-07-15 2012-12-27 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア Peptides that can control uptake in cells
US8685891B2 (en) 2009-08-27 2014-04-01 Nuclea Biotechnologies, Inc. Method and assay for determining FAS expression
WO2011038066A2 (en) * 2009-09-25 2011-03-31 Alcon Research, Ltd. Novel npr-b agonists
JP5893561B2 (en) 2009-09-25 2016-03-23 シャイア・オーファン・セラピーズ・ゲーエムベーハーＳｈｉｒｅ Ｏｒｐｈａｎ Ｔｈｅｒａｐｉｅｓ ＧｍｂＨ Novel NPR-B agonist
US20120180150A1 (en) * 2009-09-29 2012-07-12 Takahiro Fujimoto Inositol 1,4,5-triphosphate receptor-binding protein and its non-human transgenic mammalian animals
US8828395B2 (en) 2009-12-11 2014-09-09 Atyr Pharma, Inc. Antibodies that bind tyrosyl-tRNA synthetases
EP2939689B1 (en) 2009-12-11 2017-09-13 aTyr Pharma, Inc. Glutaminyl tRNA synthetases for use in the treatment of inflammatory disorders
US20110150885A1 (en) * 2009-12-11 2011-06-23 Atyr Pharma, Inc. Aminoacyl trna synthetases for modulating hematopoiesis
US9023802B2 (en) * 2009-12-14 2015-05-05 Immatics Biotechnologies Gmbh HLA-binding peptides derived from prostate-associated antigenic molecules and methods of use thereof
AR078446A1 (en) 2009-12-18 2011-11-09 Alcon Res Ltd NPR-B AGONISTS. USE.
PL3342786T3 (en) 2010-01-29 2021-12-20 Chugai Seiyaku Kabushiki Kaisha Anti-dll3 antibody
US8609092B2 (en) 2010-02-08 2013-12-17 Agensys, Inc. Antibody drug conjugates (ADC) that bind to 161P2F10B proteins
GB201002413D0 (en) 2010-02-12 2010-03-31 Procarta Biosystems Ltd Nucleic acid complexes
JP5655254B2 (en) * 2010-02-16 2015-01-21 国立大学法人京都工芸繊維大学 Polycarbonate and / or polymethyl methacrylate affinity peptide and use thereof
GB201005545D0 (en) * 2010-04-01 2010-05-19 Procarta Biosystems Ltd Transcription factor decoys
WO2011139714A2 (en) 2010-04-26 2011-11-10 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of cysteinyl-trna synthetase
ES2638311T3 (en) 2010-04-27 2017-10-19 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic and antibody compositions related to threonyl protein fragments tRNA synthetases
CN103096911B (en) 2010-04-27 2018-05-29 Atyr 医药公司 Treatment relevant with the protein fragments of Isoleucyl-tRNA synthetase, diagnosis and the innovation of antibody compositions are found
WO2011139853A2 (en) 2010-04-28 2011-11-10 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of alanyl trna synthetases
WO2011150279A2 (en) 2010-05-27 2011-12-01 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glutaminyl-trna synthetases
AU2011248457B2 (en) 2010-04-29 2017-02-16 Pangu Biopharma Limited Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of valyl tRNA synthetases
CN103097523B (en) 2010-04-29 2016-09-28 Atyr医药公司 The innovation for the treatment of, diagnosis and the antibody compositions relevant to the protein fragments of Asparaginyl-tRNA synthetase finds
US8961961B2 (en) 2010-05-03 2015-02-24 a Tyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related protein fragments of arginyl-tRNA synthetases
US8981045B2 (en) 2010-05-03 2015-03-17 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of methionyl-tRNA synthetases
CN103108655B (en) 2010-05-03 2017-04-05 Atyr 医药公司 Treatment, diagnosis and the innovation of antibody compositions related to the protein fragments of seryl tRNA synzyme finds
CN105820252B (en) 2010-05-03 2020-07-21 Atyr 医药公司 Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl- α -tRNA synthetases
EP2566492B1 (en) 2010-05-04 2016-10-26 aTyr Pharma, Inc. Innovative discovery of therapeutic compositions related to protein fragments of glutamyl-prolyl-trna synthetases
CA2798139C (en) 2010-05-04 2019-09-24 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of p38 multi-trna synthetase complex
CN103200953B (en) 2010-05-14 2017-02-15 Atyr 医药公司 Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-beta-trna synthetases
AU2011256366C1 (en) 2010-05-17 2017-06-15 Pangu Biopharma Limited Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of leucyl-tRNA synthetases
WO2011146942A1 (en) * 2010-05-21 2011-11-24 The Translational Genomics Research Institute Methods and kits to analyze microrna by nucleic acid sequencing
EP3168226A3 (en) 2010-05-31 2017-07-26 London Health Sciences Centre Research Inc. Rhamm binding peptides
EP2575857B1 (en) 2010-06-01 2018-01-24 aTyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of lysyl-trna synthetases
US20130202576A1 (en) 2010-07-12 2013-08-08 Pangu Biopharma Limited Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of histidyl-trna synthetases
AU2011289831C1 (en) 2010-07-12 2017-06-15 Pangu Biopharma Limited Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-tRNA synthetases
CN103124561B (en) 2010-07-12 2017-05-03 Atyr 医药公司 Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of aspartyl-trna synthetases
US8999321B2 (en) 2010-07-12 2015-04-07 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-tRNA synthetases
EP2606152B1 (en) * 2010-08-18 2016-10-05 Fred Hutchinson Cancer Research Center Methods for determining the presence or risk of developing facioscapulohumeral dystrophy (fshd)
CN103108650A (en) 2010-08-25 2013-05-15 Atyr医药公司 Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of tyrosyl-trna synthetases
KR20140016240A (en) 2010-09-27 2014-02-07 제스타겐, 에스.아. Compositions and methods for treating neoplasia
KR20130130709A (en) 2010-09-29 2013-12-02 어젠시스 인코포레이티드 Antibody drug conjugates (adc) that bind to 191p4d12 proteins
WO2012048125A2 (en) 2010-10-06 2012-04-12 Atyr Pharma, Inc. Innovative discovery of therapeutic, diagnostic, and antibody compositions related protein fragments of tryptophanyl trna synthetases
CA2821582A1 (en) * 2010-12-14 2012-06-21 Immatics Biotechnologies Gmbh Hla-binding peptides derived from prostate-associated antigenic molecules and methods of use thereof
WO2012112842A2 (en) 2011-02-17 2012-08-23 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health & Human Services Compositions and methods for treating poliovirus
US10370417B2 (en) 2011-03-01 2019-08-06 Rutgers, The State University Of New Jersey Methods for the diagnosis of cancer through detection of human endogenous retrovirus WL (HERV-WL) envelope expression
WO2012118974A2 (en) * 2011-03-01 2012-09-07 University Of Medicine And Dentistry Of New Jersey Detection of human endogenous retrovirus expression in cancer and normal cells
SI3173427T1 (en) 2011-03-31 2019-08-30 ADC Therapeutics SA, Antibodies against kidney associated antigen 1 and antigen binding fragments thereof
EP2511295A1 (en) * 2011-04-15 2012-10-17 Institut National De La Sante Et De La Recherche Medicale Compositions for preventing and/or treating an infection by an HIV-1 virus
US10654916B2 (en) 2011-04-21 2020-05-19 The Regents Of The University Of California, A California Corporation Compositions and methods for the treatment of neuromyelitis optica
EP3473273A1 (en) 2011-07-29 2019-04-24 Avelas Biosciences, Inc. Selective delivery molecules and methods of use
US9714419B2 (en) 2011-08-09 2017-07-25 Atyr Pharma, Inc. PEGylated tyrosyl-tRNA synthetase polypeptides
SG10201601840RA (en) 2011-09-09 2016-04-28 Agency Science Tech & Res P53 activating peptides
US20130084582A1 (en) 2011-10-04 2013-04-04 Err-Cheng Chan Serological markers for detecting colorectal cancer and their application for inhibiting colorectal cancer cells
WO2013063010A1 (en) * 2011-10-26 2013-05-02 Nuclea Biotechnologies, Inc. Usp2a peptides and antibodies
US9816084B2 (en) 2011-12-06 2017-11-14 Atyr Pharma, Inc. Aspartyl-tRNA synthetases
US9822353B2 (en) 2011-12-06 2017-11-21 Atyr Pharma, Inc. PEGylated aspartyl-tRNA synthetase polypeptides
US9688978B2 (en) 2011-12-29 2017-06-27 Atyr Pharma, Inc. Aspartyl-tRNA synthetase-Fc conjugates
CN111298119A (en) 2012-01-09 2020-06-19 Adc治疗股份有限公司 Methods for treating triple negative breast cancer and basal-like breast cancer by using inhibitors of kidney associated antigen 1(KAAG1)
EP3311847A1 (en) 2012-02-16 2018-04-25 Atyr Pharma, Inc. Histidyl-trna synthetases for treating autoimmune and inflammatory diseases
WO2013167153A1 (en) 2012-05-09 2013-11-14 Ganymed Pharmaceuticals Ag Antibodies useful in cancer diagnosis
WO2013174404A1 (en) 2012-05-23 2013-11-28 Ganymed Pharmaceuticals Ag Combination therapy involving antibodies against claudin 18.2 for treatment of cancer
EP2856172A4 (en) 2012-05-25 2016-03-02 Univ Vermont Compositions and methods for assaying platelet reactivity and treatment selection
EP2861622A4 (en) 2012-06-15 2016-06-01 Sinomab Bioscience Ltd Anti-cd22 anti-idiotypic antibodies and uses thereof
US9957557B2 (en) * 2012-08-13 2018-05-01 Life Genetics Lab, Llc Development of a highly sensitive quantification system for assessing DNA degradation and quality in forensic samples
US10093736B2 (en) 2012-11-13 2018-10-09 Biontech Ag Agents for treatment of claudin expressing cancer diseases
WO2014120837A2 (en) 2013-01-29 2014-08-07 The Regents Of The University Of California Pretargeted activatable cell penetrating peptide with intracellulary releaseable prodrug
CA3128911C (en) 2013-01-30 2023-10-17 Avelas Biosciences, Inc. Selective delivery molecules and methods of use
WO2014127785A1 (en) 2013-02-20 2014-08-28 Ganymed Pharmaceuticals Ag Combination therapy involving antibodies against claudin 18.2 for treatment of cancer
EP2961831B1 (en) 2013-02-26 2020-06-10 Memorial Sloan Kettering Cancer Center Compositions and methods for immunotherapy
US9243059B2 (en) 2013-03-12 2016-01-26 Decimmune Therapeutics, Inc. Humanized anti-N2 antibodies and methods of treating ischemia-reperfusion injury
EP2970884A4 (en) 2013-03-14 2016-11-02 Univ Florida Di-amino acid repeat-containing proteins associated with als
EP3460054B1 (en) 2013-03-15 2020-10-21 aTyr Pharma, Inc. Histidyl-trna synthetase-fc conjugates
EP2968492B1 (en) 2013-03-15 2021-12-15 Memorial Sloan-Kettering Cancer Center Compositions and methods for immunotherapy
WO2014146672A1 (en) 2013-03-18 2014-09-25 Ganymed Pharmaceuticals Ag Therapy involving antibodies against claudin 18.2 for treatment of cancer
DK2981607T3 (en) 2013-04-03 2020-11-16 Memorial Sloan Kettering Cancer Center EFFICIENT GENERATION OF TUMOR-TARGETED T-CELLS DERIVED FROM PLURIPOTENT STEM CELLS
WO2014189468A1 (en) 2013-05-20 2014-11-27 Nanyang Technological University Peptides binding to parallel-stranded g-quadruplexes
KR101841211B1 (en) * 2014-03-10 2018-03-22 한양대학교 산학협력단 Cell penetrating peptide and method for delivery of biologically active materials using it
WO2015176010A1 (en) 2014-05-15 2015-11-19 The United States Of America, As Represented By The Secretary, Departmentof Health & Human Services Treatment or prevention of an intestinal disease or disorder
AU2015269219B2 (en) 2014-06-06 2020-12-24 Memorial Sloan-Kettering Cancer Center Mesothelin-targeted chimeric antigen receptors and uses thereof
BR112017001860A2 (en) 2014-07-31 2018-02-27 Uab Research Foundation synthetic peptide, pharmaceutical composition, methods, dosage regimen, and monoclonal antibody
US10925980B2 (en) 2014-08-04 2021-02-23 Case Western Reserve University Molecular probes and methods of use
EP3677285B1 (en) 2014-08-04 2023-12-13 Case Western Reserve University Targeting peptides for detecting prostate cancer
EP3186368B1 (en) 2014-08-25 2020-01-15 Geneweave Biosciences Inc. Non-replicative transduction particles and transduction particle-based reporter systems
US10385380B2 (en) 2014-10-02 2019-08-20 The Regents Of The University Of California Personalized protease assay to measure protease activity in neoplasms
KR101693431B1 (en) 2014-11-18 2017-01-06 울산대학교 산학협력단 Targeting Peptides for Gastric Cancer and Medical Use Thereof
DK3227432T3 (en) 2014-12-05 2023-10-23 Memorial Sloan Kettering Cancer Center Chimeric antigen receptors targeting b-cell maturation antigen and uses thereof
CN107206076B (en) 2014-12-05 2021-07-09 纪念斯隆-凯特琳癌症中心 Antibodies targeting B-cell maturation antigens and uses thereof
SG10201913937QA (en) 2014-12-05 2020-03-30 Memorial Sloan Kettering Cancer Center Antibodies targeting g-protein coupled receptor and methods of use
EP3227436A4 (en) 2014-12-05 2018-06-20 Memorial Sloan Kettering Cancer Center Chimeric antigen receptors targeting fc receptor-like 5 and uses thereof
PL3227339T3 (en) 2014-12-05 2022-02-21 Memorial Sloan-Kettering Cancer Center Chimeric antigen receptors targeting g-protein coupled receptor and uses thereof
WO2016122865A1 (en) 2015-01-30 2016-08-04 Salk Institute For Biological Studies Compositions and methods for treating age-related diabetes and related disorders
IL284985B2 (en) 2015-02-18 2023-03-01 Enlivex Therapeutics R& D Ltd Combination immune therapy and cytokine control therapy for cancer treatment
US11000548B2 (en) 2015-02-18 2021-05-11 Enlivex Therapeutics Ltd Combination immune therapy and cytokine control therapy for cancer treatment
US11318163B2 (en) 2015-02-18 2022-05-03 Enlivex Therapeutics Ltd Combination immune therapy and cytokine control therapy for cancer treatment
US11497767B2 (en) 2015-02-18 2022-11-15 Enlivex Therapeutics R&D Ltd Combination immune therapy and cytokine control therapy for cancer treatment
US11596652B2 (en) 2015-02-18 2023-03-07 Enlivex Therapeutics R&D Ltd Early apoptotic cells for use in treating sepsis
US11304976B2 (en) 2015-02-18 2022-04-19 Enlivex Therapeutics Ltd Combination immune therapy and cytokine control therapy for cancer treatment
EP4140492A1 (en) 2015-04-21 2023-03-01 Enlivex Therapeutics Rdo Ltd Therapeutic pooled blood apoptotic cell preparations and uses thereof
US10596259B2 (en) 2015-05-20 2020-03-24 The Regents Of The University Of California Tumor radiosensitization with monomethyl auristatin E (MMAE) and derivatives thereof
WO2016191246A2 (en) 2015-05-22 2016-12-01 Memorial Sloan-Kettering Cancer Center T cell receptor-like antibodies specific for a prame peptide
WO2016191263A1 (en) 2015-05-22 2016-12-01 Trustees Of Dartmouth College Therapy and kit for the prevention and treatment of cystic fibrosis
US10509045B2 (en) 2015-05-29 2019-12-17 University Of Florida Research Foundation, Incorporated Methods for diagnosing Huntington's disease
GB201511546D0 (en) 2015-07-01 2015-08-12 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers
EP3919507A3 (en) 2015-07-01 2022-01-12 Immatics Biotechnologies GmbH Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers
WO2017023859A1 (en) 2015-07-31 2017-02-09 Memorial Sloan-Kettering Cancer Center Antigen-binding proteins targeting cd56 and uses thereof
MX2018001040A (en) * 2015-08-28 2018-06-15 Curevac Ag Artificial nucleic acid molecules.
GB201515321D0 (en) 2015-08-28 2015-10-14 Immatics Biotechnologies Gmbh Novel peptides, combination of peptides and scaffolds for use in immunotherapeutic treatment of various cancers
UA125817C2 (en) 2015-08-28 2022-06-15 Імматікс Біотекнолоджіс Гмбх Peptides and combination of peptides for use in immunotherapy against small cell lung cancer and other cancers
WO2017040526A2 (en) * 2015-09-01 2017-03-09 Eisai R&D Management Co., Ltd. Splice variants associated with neomorphic sf3b1 mutants
CA2997551A1 (en) 2015-09-04 2017-03-09 Memorial Sloan Kettering Cancer Center Immune cell compositions and methods of use
KR101841241B1 (en) * 2015-09-10 2018-03-22 한양대학교 산학협력단 fusion peptides associated with inflammatory skin disease and phamaceutical composition comprising the same
EP3383913A4 (en) 2015-12-04 2019-10-30 Memorial Sloan-Kettering Cancer Center Antibodies targeting fc receptor-like 5 and methods of use
WO2017100428A1 (en) 2015-12-09 2017-06-15 Memorial Sloan Kettering Cancer Center Immune cell compositions and methods of using same
WO2017124001A2 (en) 2016-01-14 2017-07-20 Memorial Sloan-Kettering Cancer Center T cell receptor-like antibodies specific for foxp3-derived peptides
JP6884155B2 (en) 2016-02-18 2021-06-09 エンリヴェックス セラピューティクス リミテッド Combination immunotherapy and cytokine control therapy for cancer treatment
GB201604490D0 (en) 2016-03-16 2016-04-27 Immatics Biotechnologies Gmbh Peptides combination of peptides for use in immunotherapy against cancers
JP2019515894A (en) 2016-04-04 2019-06-13 ユニバーシティ オブ フロリダ リサーチ ファンデーション インコーポレーティッド Manipulation of EIF3 to regulate repeat-related non-ATG (RAN) translation
KR102437015B1 (en) 2016-04-15 2022-08-29 메모리얼 슬로안 케터링 캔서 센터 Transgenic T Cells and Chimeric Antigen Receptor T Cell Compositions and Related Methods
WO2017218949A2 (en) * 2016-06-17 2017-12-21 Aileron Therapeutics, Inc. Peptidomimetic macrocycles and uses thereof
US20180052169A1 (en) * 2016-08-22 2018-02-22 The Board Of Regents Of The University Of Texas System Tsp1 as a marker for cancer
JP2019528699A (en) 2016-08-30 2019-10-17 メモリアル スローン ケタリング キャンサー センター Immune cell compositions and methods of use for treating viruses and other infections
AU2017342555A1 (en) 2016-10-14 2019-05-30 Children's Medical Center Corporation Compositions and methods for treating diseases and disorders of the central nervous system
NZ752941A (en) 2016-11-09 2023-04-28 Intrexon Corp Frataxin expression constructs
BR112019009511A2 (en) * 2016-11-13 2019-07-30 Imagine Pharma isolated polypeptide, formulation, medicament, use of at least one polypeptide, and method of treatment.
GB201621737D0 (en) * 2016-12-20 2017-02-01 Aberystwyth Univ Compositions and methods of treatment
AU2018205888B2 (en) 2017-01-05 2021-09-02 Kahr Medical Ltd. A PD1-41BBL fusion protein and methods of use thereof
ES2916217T3 (en) 2017-01-05 2022-06-29 Kahr Medical Ltd A SIRP1 ALPHA-41BBL fusion protein and methods of using the same
WO2018127918A1 (en) 2017-01-05 2018-07-12 Kahr Medical Ltd. A sirp alpha-cd70 fusion protein and methods of use thereof
US11566060B2 (en) 2017-01-05 2023-01-31 Kahr Medical Ltd. PD1-CD70 fusion protein and methods of use thereof
EP3570670B1 (en) 2017-01-17 2024-03-06 Children's Medical Center Corporation Compositions and methods for treating lysosomal storage diseases and disorders
EP3576781B9 (en) 2017-01-18 2024-03-06 Icahn School of Medicine at Mount Sinai Neoantigens and uses thereof for treating cancer
US11260101B2 (en) * 2017-02-28 2022-03-01 Jinan University Repair peptide for use in promoting post-traumatic tissue repair and regeneration, and application thereof
AU2018231190B2 (en) 2017-03-08 2023-05-25 Memorial Sloan Kettering Cancer Center Immune cell compositions and methods of use
JP7247101B2 (en) 2017-04-03 2023-03-28 エフ・ホフマン－ラ・ロシュ・アクチェンゲゼルシャフト Antibody that binds to STEAP-1
WO2018195110A1 (en) 2017-04-17 2018-10-25 University Of Florida Research Foundation, Incorporated Regolation of ran translation by pkr and eif2a-p pathways
WO2018195338A1 (en) 2017-04-20 2018-10-25 Atyr Pharma, Inc. Compositions and methods for treating lung inflammation
TW201907937A (en) 2017-05-08 2019-03-01 美商葛利史東腫瘤科技公司 Alpha virus new antigen vector
CA3063464A1 (en) * 2017-05-19 2018-11-22 Encoded Therapeutics, Inc. High activity regulatory elements
WO2019067587A1 (en) 2017-09-26 2019-04-04 University Of Florida Research Foundation, Incorporated Use of metformin and analogs thereof to reduce ran protein levels in the treatment of neurological disorders
EP3687629A4 (en) 2017-09-27 2021-10-06 University of Georgia Research Foundation Treatment and detection of infection and disease associated with different fungal pathogens
CN111655270A (en) 2017-11-14 2020-09-11 纪念斯隆-凯特琳癌症中心 IL-36 secreting immunoresponsive cells and uses thereof
US11008602B2 (en) 2017-12-20 2021-05-18 Roche Molecular Systems, Inc. Non-replicative transduction particles and transduction particle-based reporter systems
JP7314146B2 (en) 2017-12-28 2023-07-25 中外製薬株式会社 Cytotoxicity-inducing therapeutic agent
KR20200106051A (en) 2017-12-29 2020-09-10 메모리얼 슬로안 케터링 캔서 센터 Improved chimeric antigen receptor and uses thereof
KR20200118029A (en) 2018-01-04 2020-10-14 아이코닉 테라퓨틱스, 인코포레이티드 Anti-tissue factor antibodies, antibody-drug conjugates, and related methods
JP7438953B2 (en) 2018-02-01 2024-02-27 イノベント バイオロジックス （スウツォウ） カンパニー，リミテッド Fully humanized anti-B cell maturation antigen (BCMA) single chain antibody and its applications
SG11202007622SA (en) 2018-02-11 2020-09-29 Memorial Sloan Kettering Cancer Center Non-hla restricted t cell receptors and uses thereof
WO2019161133A1 (en) 2018-02-15 2019-08-22 Memorial Sloan Kettering Cancer Center Foxp3 targeting agent compositions and methods of use for adoptive cell therapy
CN112055598A (en) 2018-03-02 2020-12-08 迪克纳制药公司 Compositions and methods for inhibiting GYS2 expression
CN112543773A (en) 2018-07-11 2021-03-23 卡尔医学有限公司 SIRP alpha-4-1 BBL variant fusion proteins and methods of use thereof
MX2021005751A (en) 2018-11-16 2021-10-01 Memorial Sloan Kettering Cancer Center Antibodies to mucin-16 and methods of use thereof.
WO2020198413A1 (en) 2019-03-27 2020-10-01 The Trustees Of The University Of Pennsylvania Tn-muc1 chimeric antigen receptor (car) t cell therapy
CN110256574B (en) * 2019-05-21 2020-12-04 山东大学 Fusion polypeptide and application thereof in preparing medicament for resisting depression and neurodegenerative diseases
CN114072516A (en) 2019-05-30 2022-02-18 磨石生物公司 Modified adenoviruses
EP4041745A4 (en) * 2019-10-08 2024-02-07 Univ North Carolina State Immunoglobulin purification peptides and their use
IL292542A (en) 2019-10-28 2022-06-01 Noile Immune Biotech Inc Drug for treating cancer, combination drug, drug composition, immune responsive cell, nucleic acid delivery vehicle, and product
WO2021092223A1 (en) * 2019-11-05 2021-05-14 Board Of Regents, The University Of Texas System Hla restricted hormad1 t cell receptors and uses thereof
WO2021158818A1 (en) * 2020-02-05 2021-08-12 Synthetic Genomics, Inc. Regulatory sequences for expression of transgenes
CN115916963A (en) 2020-03-27 2023-04-04 门德斯有限公司 Ex vivo use of modified cells of leukemia origin for enhancing the efficacy of adoptive cell therapy
EP4125943A1 (en) 2020-03-27 2023-02-08 Mendus B.V. In vivo use of modified cells of leukemic origin for enhancing the efficacy of adoptive cell therapy
CR20220541A (en) 2020-03-31 2022-11-28 Chugai Pharmaceutical Co Ltd Dll3-targeting multispecific antigen-binding molecules and uses thereof
US20230242666A1 (en) 2020-06-29 2023-08-03 Cell Medica, Inc. Methods and Compositions for the Reduction of Chimeric Antigen Receptor Tonic Signaling
CN116438308A (en) 2020-08-06 2023-07-14 磨石生物公司 Multi-epitope vaccine box
EP4192875A1 (en) 2020-08-10 2023-06-14 Precision BioSciences, Inc. Antibodies and fragments specific for b-cell maturation antigen and uses thereof
JP2023544337A (en) 2020-09-30 2023-10-23 ブイオーアール バイオファーマ インコーポレーテッド Chimeric antigen receptor expression system
JP2023547520A (en) 2020-11-05 2023-11-10 メンドゥス・ベスローテン・フェンノートシャップ Use of tumor-independent antigens in immunotherapy
KR20230107610A (en) 2020-11-13 2023-07-17 보르 바이오파마 인크. Methods and compositions involving genetically engineered cells expressing chimeric antigen receptors
KR20230172630A (en) 2021-03-11 2023-12-22 므네모 테라퓨틱스 Tumor Neoantigenic Peptide
WO2022189620A1 (en) 2021-03-11 2022-09-15 Institut Curie Transmembrane neoantigenic peptides
IL305809A (en) 2021-03-11 2023-11-01 Mnemo Therapeutics Tumor neoantigenic peptides and uses thereof
JP2024511941A (en) * 2021-03-11 2024-03-18 テンザ、インク． Synthetic signal peptides to direct secretion of heterologous proteins in yeast
EP4323013A2 (en) * 2021-04-13 2024-02-21 Capsida, Inc. Selected aav compositions having preferred brain enrichment
US20220348930A1 (en) 2021-04-23 2022-11-03 Baylor College Of Medicine CAR NKTs Expressing Artificial Micro RNA-Embedded shRNA for Downregulation of MHC Class I & II Expression
WO2022235832A1 (en) 2021-05-06 2022-11-10 Ludwig Institute For Cancer Research Ltd Compositions and methods for immunotherapy
EP4337763A1 (en) 2021-05-10 2024-03-20 Institut Curie Methods for the treatment of cancer, inflammatory diseases and autoimmune diseases
WO2022248602A1 (en) 2021-05-25 2022-12-01 Institut Curie Myeloid cells overexpressing bcl2
WO2023288203A2 (en) 2021-07-12 2023-01-19 Ludwig Institute For Cancer Research Ltd T cell receptors specific for tumor-associated antigens and methods of use thereof
WO2023022788A1 (en) * 2021-08-18 2023-02-23 The Regents Of The University Of California Methods and compositions for determining risk of autism spectrum disorders
WO2023064872A1 (en) 2021-10-14 2023-04-20 Precision Biosciences, Inc. Combinations of anti-bcma car t cells and gamma secretase inhibitors
WO2023192626A1 (en) * 2022-04-01 2023-10-05 The Regents Of The University Of California Methods and compositions for treating gliomas
US20240002800A1 (en) 2022-05-16 2024-01-04 Mendus B.V. Use of leukemia-derived cells for enhancing natural killer (nk) cell therapy

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6287801B1 (en) * 1996-07-22 2001-09-11 Smithkline Beecham Corporation Nucleic acids encoding the G-protein coupled receptor HNFDS78
US6555339B1 (en) * 1997-04-14 2003-04-29 Arena Pharmaceuticals, Inc. Non-endogenous, constitutively activated human protein-coupled receptors
US20030235883A1 (en) * 2000-03-31 2003-12-25 Tang Y. Tom Novel nucleic acids and polypeptides
US6436703B1 (en) * 2000-03-31 2002-08-20 Hyseq, Inc. Nucleic acids and polypeptides

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE GENBANK [online] HILLIER ET AL.: "Generation and analysis of 280,000 human expressed sequence tags", XP002905740, Database accession no. AA004350 *
DATABASE GENBANK [online] XP002905739, Database accession no. AL135937 *
GENOME RES., vol. 6, no. 9, 7 May 1997 (1997-05-07), pages 807 - 828 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9409942B2 (en) 1997-01-08 2016-08-09 Life Technologies Corporation Methods for production of proteins

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