WO2001075067A8 - Novel nucleic acids and polypeptides - Google Patents
Novel nucleic acids and polypeptidesInfo
- Publication number
- WO2001075067A8 WO2001075067A8 PCT/US2001/008631 US0108631W WO0175067A8 WO 2001075067 A8 WO2001075067 A8 WO 2001075067A8 US 0108631 W US0108631 W US 0108631W WO 0175067 A8 WO0175067 A8 WO 0175067A8
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- nucleic acids
- polypeptides
- novel nucleic
- novel
- present
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/450,763 US20050196754A1 (en) | 2000-03-31 | 2001-03-30 | Novel nucleic acids and polypeptides |
AU2001249251A AU2001249251A1 (en) | 2000-03-31 | 2001-03-30 | Novel nucleic acids and polypeptides |
US10/128,558 US20040219521A1 (en) | 2000-01-21 | 2002-04-22 | Novel nucleic acids and polypeptides |
US10/243,552 US20030224379A1 (en) | 2000-01-21 | 2002-09-12 | Novel nucleic acids and polypeptides |
US10/302,689 US20080050393A1 (en) | 1998-12-03 | 2002-11-22 | Novel nucleic acids and polypeptides |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US54021700A | 2000-03-31 | 2000-03-31 | |
US09/540,217 | 2000-03-31 | ||
US64916700A | 2000-08-23 | 2000-08-23 | |
US09/649,167 | 2000-08-23 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2001/008656 Continuation-In-Part WO2001079449A2 (en) | 1998-12-03 | 2001-04-16 | Novel nucleic acids and polypeptides |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2001/004941 Continuation-In-Part WO2002016439A2 (en) | 1998-12-03 | 2001-03-05 | Novel nucleic acids and polypeptides |
Publications (4)
Publication Number | Publication Date |
---|---|
WO2001075067A2 WO2001075067A2 (en) | 2001-10-11 |
WO2001075067A3 WO2001075067A3 (en) | 2002-04-04 |
WO2001075067A9 WO2001075067A9 (en) | 2002-10-31 |
WO2001075067A8 true WO2001075067A8 (en) | 2004-10-14 |
Family
ID=27066367
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2001/008631 WO2001075067A2 (en) | 1998-12-03 | 2001-03-30 | Novel nucleic acids and polypeptides |
Country Status (3)
Country | Link |
---|---|
US (7) | US6436703B1 (en) |
AU (1) | AU2001249251A1 (en) |
WO (1) | WO2001075067A2 (en) |
Families Citing this family (566)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5972697A (en) | 1995-11-13 | 1999-10-26 | The Salk Institute For Biological Studies | NIMA interacting proteins |
US7125677B2 (en) | 1995-11-13 | 2006-10-24 | The Salk Institute For Biological Studies | NIMA interacting proteins |
US7351421B2 (en) * | 1996-11-05 | 2008-04-01 | Hsing-Wen Sung | Drug-eluting stent having collagen drug carrier chemically treated with genipin |
US20050163818A1 (en) * | 1996-11-05 | 2005-07-28 | Hsing-Wen Sung | Drug-eluting device chemically treated with genipin |
JP2001512306A (en) | 1997-01-08 | 2001-08-21 | ライフ テクノロジーズ,インコーポレイテッド | Methods for producing proteins |
US20030082540A1 (en) * | 1997-09-17 | 2003-05-01 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US7417126B2 (en) * | 1997-10-17 | 2008-08-26 | Genentech, Inc. | PRO246 antibodies |
JP2002504331A (en) * | 1998-02-19 | 2002-02-12 | スミスクライン ビーチャム コーポレーション | G protein-coupled receptor AmMaid |
US6696247B2 (en) | 1998-03-18 | 2004-02-24 | Corixa Corporation | Compounds and methods for therapy and diagnosis of lung cancer |
US6960570B2 (en) | 1998-03-18 | 2005-11-01 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of lung cancer |
US7258860B2 (en) | 1998-03-18 | 2007-08-21 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of lung cancer |
US7579160B2 (en) | 1998-03-18 | 2009-08-25 | Corixa Corporation | Methods for the detection of cervical cancer |
EP1086223B1 (en) | 1998-06-01 | 2009-07-29 | Agensys, Inc. | Novel serpentine transmembrane antigens expressed in human cancers and uses thereof |
US20030149531A1 (en) | 2000-12-06 | 2003-08-07 | Hubert Rene S. | Serpentine transmembrane antigens expressed in human cancers and uses thereof |
US6833438B1 (en) | 1999-06-01 | 2004-12-21 | Agensys, Inc. | Serpentine transmembrane antigens expressed in human cancers and uses thereof |
US7339033B2 (en) * | 1998-06-26 | 2008-03-04 | Genentech, Inc. | Pro1481 |
US7091315B1 (en) | 1998-07-15 | 2006-08-15 | Human Genome Sciences, Inc. | Protein HDPBQ71 |
US20070072248A1 (en) * | 1998-10-13 | 2007-03-29 | Arena Pharmaceuticals, Inc. | Constitutively activated human G protein coupled receptors |
US20030229216A1 (en) * | 1998-10-13 | 2003-12-11 | Ruoping Chen | Constitutively activated human G protein coupled receptors |
US20080213778A1 (en) | 1998-12-30 | 2008-09-04 | Millennium Pharmaceuticals, Inc. | Novel genes encoding proteins having prognostic, diagnostic, preventive, therapeutic, and other uses |
US20030190669A1 (en) | 1998-12-30 | 2003-10-09 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
US7041474B2 (en) | 1998-12-30 | 2006-05-09 | Millennium Pharmaceuticals, Inc. | Nucleic acid encoding human tango 509 |
US7235642B1 (en) * | 1999-01-12 | 2007-06-26 | Genentech, Inc. | Anti-PRO 1313 antibodies |
US6303321B1 (en) | 1999-02-11 | 2001-10-16 | North Shore-Long Island Jewish Research Institute | Methods for diagnosing sepsis |
US6649342B1 (en) | 1999-03-15 | 2003-11-18 | Eos Biotechnology, Inc. | Methods of diagnosing breast cancer, compositions, and methods of screening for breast cancer modulators |
US6943235B1 (en) | 1999-04-12 | 2005-09-13 | Agensys, Inc. | Transmembrane protein expressed in prostate cancer |
AU6394400A (en) * | 1999-07-30 | 2001-02-19 | Millennium Pharmaceuticals, Inc. | Secreted proteins and uses thereof |
EP1218411A4 (en) * | 1999-09-20 | 2004-09-01 | Millennium Pharm Inc | Secreted proteins and uses thereof |
US20030228640A1 (en) * | 1999-10-15 | 2003-12-11 | University Of Pittsburgh | Nuclear matrix proteins, polynucleotide sequences encoding them, and their use |
CA2490853A1 (en) * | 1999-12-01 | 2001-06-07 | Genentech, Inc. | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
JP2003515325A (en) * | 1999-12-01 | 2003-05-07 | ヒューマン ジノーム サイエンシーズ, インコーポレイテッド | Four disulfide core domain containing (FDCD) polynucleotides, polypeptides, and antibodies |
ES2360155T3 (en) | 2000-01-26 | 2011-06-01 | Agensys, Inc. | 84P2A9: A SPECIFIC PROTEIN OF PROSTATE AND TESTICLES HIGHLY EXPRESSED IN PROSTATE CANCER. |
AU2001236658A1 (en) * | 2000-02-03 | 2001-08-14 | Nuvelo, Inc. | Methods and materials relating to neurotrimin-like polypeptides and polynucleotides |
US6806254B2 (en) * | 2000-02-03 | 2004-10-19 | Nuvelo, Inc. | Methods and materials relating to alpha-2-macroglobulin-like polypeptides and polynucleotides |
US7700341B2 (en) | 2000-02-03 | 2010-04-20 | Dendreon Corporation | Nucleic acid molecules encoding transmembrane serine proteases, the encoded proteins and methods based thereon |
AU2001241446A1 (en) * | 2000-02-03 | 2001-08-14 | Lexicon Genetics Incorporated | Human transporter proteins and polynucleotides encoding the same |
WO2002026803A2 (en) * | 2000-09-25 | 2002-04-04 | Millenium Pharmaceuticals, Inc. | 22108 and 47916, novel human thioredoxin family members and uses thereof |
PT1276867E (en) * | 2000-03-22 | 2006-12-29 | Bayer Healthcare Ag | Use of human latrophilin-like g protein-coupled receptor in screening methods |
WO2001075075A2 (en) * | 2000-03-27 | 2001-10-11 | Bayer Aktiengesellschaft | Human tyrosine phosphatase-like enzymes |
AU5521401A (en) * | 2000-03-31 | 2001-10-15 | Hyseq Inc | Method and materials relating to insulin-like growth factor binding protein-likepolypeptides and polynucleotides |
US6436703B1 (en) * | 2000-03-31 | 2002-08-20 | Hyseq, Inc. | Nucleic acids and polypeptides |
EP1268762A4 (en) * | 2000-03-31 | 2003-08-27 | Nuvelo Inc | Novel nucleic acids and polypeptides |
GB0008305D0 (en) * | 2000-04-06 | 2000-05-24 | Neutec Pharma Plc | Treatment of fungal infections |
JP2003530873A (en) * | 2000-04-19 | 2003-10-21 | メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング | NK-2 homeobox transcription regulator |
US7371388B1 (en) | 2000-05-04 | 2008-05-13 | Human Genome Sciences, Inc. | Treatment of Sjogren's syndrome by administration of TR18 polypeptides |
AU6531101A (en) * | 2000-06-02 | 2001-12-17 | Genentech Inc | Secreted and transmembrane polypeptides and nucleic acids encoding the same |
EP1395655A2 (en) | 2000-06-06 | 2004-03-10 | Millennium Pharmaceuticals, Inc. | 52906, 33408, and 12189, potassium channel family members and uses thereof |
WO2001094614A2 (en) * | 2000-06-07 | 2001-12-13 | Cyclacel Limited | Methods for monitoring enzyme activity |
EP1309676A2 (en) * | 2000-06-12 | 2003-05-14 | Bayer Aktiengesellschaft | Human epithin-like serine protease |
EP1293510A4 (en) * | 2000-06-22 | 2005-02-09 | Takeda Pharmaceutical | Novel polypeptide and its dna |
PT1297006E (en) | 2000-06-23 | 2006-05-31 | Bayer Healthcare Ag | REGULATION OF SERENIAL PROTEASE SIMILAR TO HUMAN PROSTASIN |
AU2001272493A1 (en) * | 2000-06-26 | 2002-01-08 | Merck Patent G.M.B.H | Receptor for phosphoinositides-1 associated scaffold protein |
DK1325115T3 (en) * | 2000-06-26 | 2016-11-21 | Zymogenetics Inc | CYTOKINRECEPTOR ZCYTOR17 |
EP1294882A2 (en) * | 2000-06-28 | 2003-03-26 | Amgen, Inc. | B7-like molecules and uses thereof |
US7355023B2 (en) * | 2000-06-29 | 2008-04-08 | Duke University | Isolated nucleic acids and polypeptides associated with glucose homeostasis disorders and method of detecting the same |
US20020064821A1 (en) * | 2000-07-05 | 2002-05-30 | Merkulov Gennady V. | Isolated human ion channel proteins, nucleic acid molecules encoding human ion channel proteins, and uses thereof |
US20030171324A1 (en) * | 2000-07-18 | 2003-09-11 | Shyam Ramakrishnan | Regulation of human desc1-like serine protease |
AU2001278488A1 (en) * | 2000-07-25 | 2002-02-05 | Bayer Aktiengesellschaft | Regulation of human matriptase-like serine protease |
US7402660B2 (en) | 2000-08-02 | 2008-07-22 | The Johns Hopkins University | Endothelial cell expression patterns |
US6924364B2 (en) | 2000-08-04 | 2005-08-02 | Zymogenetics, Inc. | Human secreted protein, Zzp1 |
WO2002012469A2 (en) * | 2000-08-09 | 2002-02-14 | Millennium Pharmaceuticals, Inc. | A human adenylate kinase family member and uses therefor |
DK1313766T3 (en) * | 2000-08-21 | 2008-10-27 | Organon Nv | Coaster, a human coactivator for steroid receptors |
ATE328899T1 (en) | 2000-09-22 | 2006-06-15 | Kyowa Hakko Kogyo Kk | CELL NUCLEAR LOCALIZING PROTEIN FOR BETA-CATENIN |
AU2002210514A1 (en) * | 2000-09-27 | 2002-04-08 | Bayer Aktiengesellschaft | Regulation of human phosphatidylinositol-specific phospholipase c-like enzyme |
WO2002029058A2 (en) * | 2000-10-05 | 2002-04-11 | Curagen Corporation | Human proteins, polynucleotides encoding them and methods of using the same |
WO2002029049A2 (en) * | 2000-10-05 | 2002-04-11 | Bayer Aktiengesellschaft | Regulation of human sodium-dependent monoamine transporter |
US20030124704A1 (en) * | 2000-10-06 | 2003-07-03 | Strittmatter Stephen M. | Nogo receptor homologs |
WO2002030974A2 (en) * | 2000-10-12 | 2002-04-18 | Curagen Corporation | Proteins and nucleic acids encoding same |
EP1326979A2 (en) * | 2000-10-18 | 2003-07-16 | ZymoGenetics, Inc. | Human cyclic nucleotide binding protein |
JP4460829B2 (en) * | 2000-10-20 | 2010-05-12 | コモ・バイオテック・アンパルトセルスカブ | Pregnancy-related plasma protein-A2 (PAPP-A2) |
US20030068624A1 (en) * | 2000-10-26 | 2003-04-10 | Recipon Herve E. | Compositions and methods relating to lung specific genes and proteins |
AU2002243444A1 (en) | 2000-10-31 | 2002-06-24 | Diadexus, Inc. | Compositions and methods relating to colon specific genes and proteins |
WO2002050278A2 (en) * | 2000-11-15 | 2002-06-27 | Lexicon Genetics Incorporated | Novel human secreted proteins and polynucleotides encoding the same |
ES2349114T3 (en) * | 2000-11-22 | 2010-12-28 | University Of Maryland, Baltimore | USE OF CLYA HEMOLISIN FOR THE EXCRETION OF FUSION PROTEINS. |
AU2002233201A1 (en) * | 2000-11-27 | 2002-06-03 | Bayer Aktiengesellschaft | Regulation of human tyrosine phosphatase |
US20020081653A1 (en) * | 2000-11-28 | 2002-06-27 | Chunhua Yan | Isolated human transporter proteins, nucleic acid molecules encoding human transporter proteins, and uses thereof |
WO2002046477A2 (en) * | 2000-12-07 | 2002-06-13 | Chiron Corporation | Endogenous retroviruses up-regulated in prostate cancer |
CA2431007A1 (en) | 2000-12-11 | 2002-07-18 | Lexicon Genetics Incorporated | Novel human kinase and polynucleotides encoding the same |
DE10061931A1 (en) * | 2000-12-13 | 2001-09-06 | Marianne Kroepelin | A new nucleic acid encoding M73791 HUMNOVGENE also known as HUMQM and human RPL10 is involved in tumor suppression and useful to diagnose and treat cancer |
WO2002057460A2 (en) | 2000-12-20 | 2002-07-25 | Bristol-Myers Squibb Company | Polynucleotides encoding human phosphatases |
US6949363B2 (en) | 2000-12-22 | 2005-09-27 | Brilstol-Myers Squibb | Polynucleotides encoding novel human leucine-rich repeat containing protein expressed predominately in bone marrow, HLRRBM1 |
US7247705B2 (en) * | 2000-12-28 | 2007-07-24 | Takeda Pharmaceutical Company Limited | Proteins having glucose transporter activity |
WO2002053748A1 (en) * | 2001-01-02 | 2002-07-11 | Bayer Aktiengesellschaft | Regulation of human 3-ss-hydroxysteroid dehydrogenase-isomerase |
GB0100750D0 (en) * | 2001-01-11 | 2001-02-21 | Inpharmatica Ltd | Novel proteins |
US6605710B2 (en) * | 2001-01-11 | 2003-08-12 | Board Of Trustees Of Michigan State University | Gene whose expression promotes differentiation of myeloid progenitor cells into neutrophils and/or monocytes/macrophages |
WO2002079473A2 (en) * | 2001-01-12 | 2002-10-10 | Incyte Genomics, Inc. | Molecules for diagnostics and therapeutics |
EP1490509A4 (en) * | 2001-01-12 | 2005-06-01 | Exelixis Inc | Modulating insulin receptor signaling |
GB2375110A (en) * | 2001-01-30 | 2002-11-06 | Aeomica Inc | Human LCCL_domain containing peptides |
WO2002061049A2 (en) * | 2001-01-31 | 2002-08-08 | Millennium Pharmaceuticals, Inc. | Novel molecules of the pyrin/nbs/lrr protein family and uses thereof |
US7041643B2 (en) | 2001-01-31 | 2006-05-09 | Millennium Pharmaceuticals, Inc. | Molecules of the PYRIN/NBS/LRR protein family and uses thereof |
AU2002229440A1 (en) * | 2001-02-02 | 2002-08-19 | Mount Sinai Hospital | Human acid phosphatase gene |
US20030166041A1 (en) * | 2001-02-08 | 2003-09-04 | Hillman Jennifer L. | TIMM8b-related protein |
US7601825B2 (en) | 2001-03-05 | 2009-10-13 | Agensys, Inc. | Nucleic acid and corresponding protein entitled 121P1F1 useful in treatment and detection of cancer |
US20060035237A1 (en) | 2002-08-26 | 2006-02-16 | Markowitz Sanford D | Methods and compositions for categorizing patients |
US7081516B2 (en) | 2002-08-26 | 2006-07-25 | Case Western Reserve University | Methods for categorizing patients |
US7118912B2 (en) * | 2002-08-26 | 2006-10-10 | Case Western Reserve University | Methods and compositions for categorizing patients |
CA2439693A1 (en) * | 2001-03-05 | 2002-10-31 | Aventis Pharma S.A. | Nucleic acids of the human abcc12 gene, vectors containing such nucleic acids and uses thereof |
US6924358B2 (en) | 2001-03-05 | 2005-08-02 | Agensys, Inc. | 121P1F1: a tissue specific protein highly expressed in various cancers |
MXPA03008039A (en) | 2001-03-08 | 2004-05-24 | Immunex Corp | Human serpin polypeptides. |
US8647826B2 (en) | 2001-03-14 | 2014-02-11 | Agensys, Inc. | Nucleic acid and corresponding protein entitled 125P5C8 useful in treatment and detection of cancer |
US7271240B2 (en) | 2001-03-14 | 2007-09-18 | Agensys, Inc. | 125P5C8: a tissue specific protein highly expressed in various cancers |
AU2002250143A1 (en) * | 2001-03-16 | 2002-10-03 | Eli Lilly And Company | Lp mammalian proteins; related reagents |
US6551809B2 (en) * | 2001-03-20 | 2003-04-22 | Applera Corporation | Isolated human phosphatase proteins, nucleic acid molecules encoding human phophatase proteins, and uses thereof |
JP4590157B2 (en) | 2001-03-21 | 2010-12-01 | アイシス イノヴェイション リミテッド | Assays, methods and means |
US20040209264A1 (en) * | 2001-03-23 | 2004-10-21 | Thomas Kramps | New essential downstream component of the wingless signalling pathway |
JP2004529639A (en) * | 2001-03-23 | 2004-09-30 | バイエル アクチェンゲゼルシャフト | Regulation of human bispecific protein phosphatase 7-like protein |
NZ527971A (en) * | 2001-03-27 | 2006-03-31 | Dendreon Corp | Nucleic acid molecules encoding a transmembrane serine protease 9, the encoded polypeptides and methods based thereon |
WO2002081515A1 (en) * | 2001-04-03 | 2002-10-17 | Kyowa Hakko Kogyo Co., Ltd. | Insulin-like growth factor-binding protein |
WO2002088303A2 (en) | 2001-04-03 | 2002-11-07 | Bristol-Myers Squibb Company | Polynucleotide encoding a novel cysteine protease of the calpain superfamily, can-12, and variants thereof |
AU2002258626B2 (en) | 2001-04-10 | 2007-01-18 | Agensys, Inc. | Nucleid acid and corresponding protein entitled 158P3D2 useful in treatment and detection of cancer |
WO2002083921A2 (en) | 2001-04-10 | 2002-10-24 | Agensys, Inc. | Nuleic acids and corresponding proteins useful in the detection and treatment of various cancers |
AU2002303340A1 (en) | 2001-04-10 | 2002-10-28 | Agensys, Inc. | Nucleic acid and corresponding protein entitled 184p1e2 useful in treatment and detection of cancer |
US20030191073A1 (en) | 2001-11-07 | 2003-10-09 | Challita-Eid Pia M. | Nucleic acid and corresponding protein entitled 161P2F10B useful in treatment and detection of cancer |
WO2002083866A2 (en) * | 2001-04-17 | 2002-10-24 | The Board Of Trustees Of The University Of Arkansas | Repeat sequences of the ca125 gene and their use for diagnostic and therapeutic interventions |
US7309760B2 (en) * | 2001-04-17 | 2007-12-18 | The Board Of Trustees Of The University Of Arkansas | Repeat sequences of the CA125 gene and their use for diagnostic and therapeutic interventions |
CA2444504A1 (en) * | 2001-04-26 | 2002-11-07 | Pe Corporation (Ny) | Isolated human secreted proteins, nucleic acid molecules encoding human secreted proteins, and uses thereof |
US7713526B2 (en) | 2001-05-01 | 2010-05-11 | The Regents Of The University Of California | Wnt and frizzled receptors as targets for immunotherapy in head and neck squamous cell carcinomas |
AU2002308557A1 (en) | 2001-05-01 | 2002-11-11 | The Regents Of The University Of California | Wnt and frizzled receptors as targets for immunotherapy in head and neck squamous cell carcinomas |
JP2004535794A (en) | 2001-05-03 | 2004-12-02 | チルドレンズ・メディカル・センター・コーポレイション | Sperm-specific cation channels and uses thereof |
US7217785B2 (en) * | 2001-05-09 | 2007-05-15 | The Regents Of The University Of California | Cysteine-containing peptides having antioxidant properties |
US20040152092A1 (en) * | 2001-05-11 | 2004-08-05 | Alex Smolyar | Regulation of human phosphatidic acid phosphatase type 2c-like protein |
US7304034B2 (en) | 2001-05-15 | 2007-12-04 | The Feinstein Institute For Medical Research | Use of HMGB fragments as anti-inflammatory agents |
US7220723B2 (en) | 2001-05-15 | 2007-05-22 | The Feinstein Institute For Medical Research | Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents |
CN100447154C (en) * | 2001-05-15 | 2008-12-31 | 费因斯坦医学研究学院 | Use of HMG fragments as anti-inflammatory agents |
WO2002095002A2 (en) * | 2001-05-22 | 2002-11-28 | University Of Chicago | N4 virion single-stranded dna dependent rna polymerase |
WO2002099134A1 (en) * | 2001-06-05 | 2002-12-12 | Auckland Uniservices Limited | Methods and compositions for assessment of pulmonary function and disorders |
WO2002098889A2 (en) * | 2001-06-05 | 2002-12-12 | Exelixis Inc. | MAP3Ks AS MODIFIER OF THE p53 PATHWAY AND METHODS OF USE |
WO2003008450A1 (en) * | 2001-06-12 | 2003-01-30 | Kyogo Itoh | Tumor antigen |
EP1266906A1 (en) * | 2001-06-13 | 2002-12-18 | Millennium Pharmaceuticals, Inc. | 46584, a human transporter family member and uses therefor |
JP2004531268A (en) * | 2001-06-14 | 2004-10-14 | レキシコン・ジェネティクス・インコーポレーテッド | Novel human transporter protein and polynucleotide encoding the same |
US20030143668A1 (en) * | 2001-06-18 | 2003-07-31 | National Institute Of Advanced Industrial | Guanosine triphosphate-binding protein coupled receptors |
US20030120040A1 (en) | 2001-06-29 | 2003-06-26 | Genentech, Inc. | Secreted and Transmembrane polypeptides and nucleic acids encoding the same |
ITMI20011465A1 (en) * | 2001-07-10 | 2003-01-10 | Novuspharma Spa | GENE WITH ONCOSUPPRESSIVE ACTIVITY |
WO2003006688A2 (en) * | 2001-07-13 | 2003-01-23 | University Of Aarhus | Methods for diagnosis and treatment of diseases associated with altered expression of gnas |
JP2003024080A (en) * | 2001-07-19 | 2003-01-28 | Univ Tokyo | Protein inducing p53-dependent apoptosis and method for screening apoptosis controlling agent |
US20040210042A1 (en) * | 2001-07-19 | 2004-10-21 | Tsuchida Jun-Ichi | Polypeptides relating to signal transfer of advanced glycation end product receptor |
WO2003010198A1 (en) * | 2001-07-26 | 2003-02-06 | Kenton Srl | Identification of specific tumour antigens by selection of cdna libraries with sera and use of said antigens in diagnostic techniques |
WO2003012038A2 (en) | 2001-07-27 | 2003-02-13 | Wyeth | Aggrecanase molecules |
WO2003024389A2 (en) | 2001-07-30 | 2003-03-27 | Immunex Corporation | T. reesei phytase enyzmes, polynucleides encoding the enzymes, vectors and host cells thereof, and methods of using |
FR2828209A1 (en) * | 2001-08-01 | 2003-02-07 | Cytomics Systems | New nucleic acid encoding HECT-domain polypeptides, useful e.g. for treatment of cancer or inflammation, also new proteins, antibodies and modulators |
JP2003135063A (en) * | 2001-08-24 | 2003-05-13 | Chiba Prefecture | New gene nedl-1 |
EP1757693A3 (en) * | 2001-08-24 | 2007-05-09 | Hisamitsu Pharmaceutical Co. Inc. | Nucleic acids showing difference in expression between hepatoblastoma and normal liver |
IL160651A0 (en) | 2001-08-31 | 2004-07-25 | Agensys Inc | Nucleic acid and correspondidng protein entitled 205pib5 and pharmaceutical compositions containing the same |
ES2537074T3 (en) | 2001-09-06 | 2015-06-02 | Agensys, Inc. | Nucleic acid and corresponding protein called STEAP-1 useful in the treatment and detection of cancer |
US7494646B2 (en) | 2001-09-06 | 2009-02-24 | Agensys, Inc. | Antibodies and molecules derived therefrom that bind to STEAP-1 proteins |
EP2339029B1 (en) * | 2001-09-14 | 2016-03-09 | Clinical Genomics Pty. Ltd | Nucleic acid markers for use in determining predisposition to neoplasm and/or adenoma |
WO2003099318A2 (en) * | 2002-05-29 | 2003-12-04 | DeveloGen Aktiengesellschaft für entwicklungsbiologische Forschung | Pancreas-specific proteins |
US20050222070A1 (en) | 2002-05-29 | 2005-10-06 | Develogen Aktiengesellschaft Fuer Entwicklungsbiologische Forschung | Pancreas-specific proteins |
AU2002326957B2 (en) * | 2001-09-19 | 2006-08-10 | The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Transductin-1 and transductin-2 and applications to hereditary deafness |
JP2003093056A (en) * | 2001-09-26 | 2003-04-02 | Japan Science & Technology Corp | ENZYME PHOSPHORYLATING Ser46 of p53 |
US20030108928A1 (en) * | 2001-10-09 | 2003-06-12 | Millennium Pharmaceuticals, Inc. | MID 241 receptor, a novel G-protein coupled receptor |
CA2463578A1 (en) * | 2001-10-16 | 2003-04-24 | Autogen Research Pty Ltd | Differentially expressed genes associated with obesity and type 2 diabetes |
US20030100034A1 (en) * | 2001-10-16 | 2003-05-29 | Millennium Pharmaceuticals, Inc. | 9136, a human aldehyde dehydrogenase family member and uses therefor |
DE10152598A1 (en) * | 2001-10-19 | 2003-05-22 | Schering Ag | ARL-2-for fertility control |
US8729248B2 (en) | 2001-10-22 | 2014-05-20 | Children's Medical Center Corporation | Sperm-specific cation channel, CATSPER2, and uses therefor |
AU2002364939A1 (en) | 2001-10-22 | 2003-07-09 | Board Of Regents, The University Of Texas System | Sperm-specific cation channel, catsper2, and uses therefor |
DE10153259A1 (en) * | 2001-10-31 | 2003-05-22 | Osram Opto Semiconductors Gmbh | Optoelectronic component |
AU2002359331A1 (en) * | 2001-10-31 | 2003-06-10 | Millennium Pharmaceuticals, Inc. | Methods and compositions for the treatment and diagnosis of cellular proliferative disorders using 32222 |
EP1446507A2 (en) * | 2001-10-31 | 2004-08-18 | Pfizer Products Inc. | Therapeutics and diagnostics for disorders of erythropoiesis |
IL161268A0 (en) | 2001-11-07 | 2004-09-27 | Agensys Inc | Nucleic acid and corresponding protein entitled 161p2f10b and pharmaceutical and diagnostic compositions containing the same |
EP1442118A2 (en) * | 2001-11-08 | 2004-08-04 | DeveloGen Aktiengesellschaft für entwicklungsbiologische Forschung | Men protein, gst2, rab-rp1, csp, f-box protein lilina/fbl7, abc50, coronin, sec61 alpha, or vhappa1-1, or homologous proteins involved in the regulation of energy homeostasis |
WO2003042370A2 (en) * | 2001-11-14 | 2003-05-22 | The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | New gene expressed in prostate cancer and methods of use |
US7074576B2 (en) * | 2001-11-23 | 2006-07-11 | Syn X Pharma, Inc. | Protein biopolymer markers indicative of alzheimer's disease |
US20030100016A1 (en) * | 2001-11-23 | 2003-05-29 | George Jackowski | Complement C3 precursor biopolymer markers predictive of Alzheimers disease |
CA2468326C (en) * | 2001-11-26 | 2015-11-17 | Pierre Legrain | Protein-protein interactions in human immunodeficiency virus |
WO2003046165A1 (en) * | 2001-11-26 | 2003-06-05 | Bayer Healthcare Ag | Regulation of human aldose reductase-like protein |
AU2002360460A1 (en) * | 2001-12-03 | 2003-06-17 | Nuvelo, Inc. | Methods and materials relating to novel polypeptides and polynucleotides |
EP1318406B1 (en) * | 2001-12-04 | 2005-11-09 | B.R.A.H.M.S Aktiengesellschaft | Use of Glycine-N-Acyl-Transferase (GNAT) for diagnosis of inflammatory diseases and sepsis |
US20060275747A1 (en) * | 2001-12-07 | 2006-12-07 | Hardy Stephen F | Endogenous retrovirus up-regulated in prostate cancer |
AU2002351332A1 (en) * | 2001-12-07 | 2003-06-23 | Chiron Corporation | Endogenous retrovirus polypeptides linked to oncogenic transformation |
GB2398786A (en) * | 2001-12-10 | 2004-09-01 | Amersham Plc | Human prostate cancer candidate protein 1 |
WO2003052119A2 (en) * | 2001-12-14 | 2003-06-26 | Incyte Genomics, Inc. | Transporters and ion channels |
AU2002357850A1 (en) * | 2001-12-14 | 2003-06-30 | Incyte Genomics, Inc. | Neurotransmission-associated proteins |
ES2337989T3 (en) * | 2001-12-18 | 2010-05-03 | Endocube Sas | NEW PROTEINS ASSOCIATED WITH THE DEATH OF THE THAP FAMILY AND RELATED PAR4 ROUTES INVOLVED IN THE CONTROL OF APOPTOSIS. |
US7858297B2 (en) * | 2001-12-18 | 2010-12-28 | Centre National De La Recherche Scientifique Cnrs | Chemokine-binding protein and methods of use |
JP3837524B2 (en) | 2001-12-19 | 2006-10-25 | 国立大学法人 長崎大学 | Nucleic acid, probe comprising the nucleic acid, and screening method using the probe |
JP2003245084A (en) | 2001-12-20 | 2003-09-02 | Morinaga Milk Ind Co Ltd | New gene useful for diagnosis and treatment of aplasia of corpus callosum and aspermatogenesis and use thereof |
US20050112618A1 (en) * | 2001-12-21 | 2005-05-26 | Fagan Richard J. | Secreted protein |
GB0130720D0 (en) * | 2001-12-21 | 2002-02-06 | Serono Internat S A | Proteins |
WO2003059938A1 (en) * | 2001-12-21 | 2003-07-24 | Ramot At Tel Aviv University Ltd. | Chromatin remodeling protein as a marker expressed by stromal progenitor cells |
WO2003060129A1 (en) * | 2002-01-16 | 2003-07-24 | Bayer Healthcare Ag | Regulation of human fatty acid coa ligase-like amp-binding enzyme |
WO2003060110A2 (en) * | 2002-01-16 | 2003-07-24 | Bayer Healthcare Ag | Regulation of human fatty acid coa ligase-like amp-binding enzyme |
US20060088828A1 (en) * | 2002-01-23 | 2006-04-27 | Harris Peter C | Polycystic kidney disease nucleic acids and proteins |
WO2003062429A1 (en) * | 2002-01-23 | 2003-07-31 | Yamanouchi Pharmaceutical Co., Ltd. | Novel serine protease |
GB0202149D0 (en) * | 2002-01-30 | 2002-03-20 | Univ Edinburgh | Pluripotency determining factors and uses thereof |
EP1474515A2 (en) * | 2002-02-01 | 2004-11-10 | Bayer HealthCare AG | Regulation of human hematopoietin receptor-like protein |
EP1485406A4 (en) * | 2002-02-20 | 2006-02-01 | Invitrogen Corp | Highly homogeneous molecular markers for electrophoresis |
EP1338606A1 (en) * | 2002-02-22 | 2003-08-27 | Magnus Von Knebel Doeberitz | Nucleic Acid encoding an HERV-H polypeptide for diagnosing colorectal cancer |
GB2388113A (en) * | 2002-03-06 | 2003-11-05 | Oxford Glycosciences | B-cell malignancy-associated protein |
JP2003259872A (en) * | 2002-03-07 | 2003-09-16 | Japan Science & Technology Corp | Human esophageal carcinoma antigenic peptide and method for diagnosing esophageal carcinoma |
JPWO2003074701A1 (en) * | 2002-03-07 | 2005-06-30 | 株式会社 ビーエフ研究所 | p18AβrP gene and p18AβrP protein, a novel gene / protein (p60TRP) that interacts with these to suppress cell death, and a substance that promotes cell death |
IL163733A0 (en) | 2002-03-08 | 2005-12-18 | Eisai Co Ltd | Presynaptic protein p120 |
DE10211088A1 (en) * | 2002-03-13 | 2003-09-25 | Ugur Sahin | Gene products differentially expressed in tumors and their use |
AU2012216265B2 (en) * | 2002-03-13 | 2015-01-22 | Biontech Ag | Genetic products differentially expressed in tumors and use thereof |
EP1491630B1 (en) * | 2002-03-14 | 2009-11-11 | National Institute of Advanced Industrial Science and Technology | N-acetylglucosamine transferase, nucleic acid encoding the same and use thereof in diagnosing cancer and/or tumor |
WO2003083078A2 (en) | 2002-03-28 | 2003-10-09 | Bristol-Myers Squibb Company | Novel human cell surface protein with immunoglobulin folds, bgs-19 |
US20040002593A1 (en) * | 2002-04-04 | 2004-01-01 | Reed John C. | PAAD domain-containing polypeptides, encoding nucleic acids, and methods of use |
AU2003222189A1 (en) * | 2002-04-05 | 2003-10-27 | Incyte Corporation | Secreted proteins |
AU2003222965A1 (en) * | 2002-04-05 | 2003-10-27 | University Court Of The University Of Edinburgh | Schizophrenia associated genes |
US7544767B2 (en) * | 2002-04-05 | 2009-06-09 | Burnham Institute For Medical Research | HMGN2 peptides and related molecules that selectively home to tumor blood vessels and tumor cells |
EP1576099A4 (en) | 2002-04-12 | 2007-07-11 | Bristol Myers Squibb Co | Novel polynucleotides encoding the human citron kinase polypeptide, bmsnkc 0020/0021 |
US7459424B2 (en) | 2002-04-22 | 2008-12-02 | The Borad Of Trustees Of The Leland Stanford Junior University | Peptide inhibitors of protein kinase C γ for pain management |
EP1576096A4 (en) * | 2002-04-23 | 2007-05-23 | Univ Georgia Res Found | N-ACETYLGLUCOSAMINYLTRANSFERASE Vb CODING SEQUENCE, RECOMBINANT CELLS AND METHODS |
US20060160728A1 (en) * | 2002-04-26 | 2006-07-20 | Heinz Von Der Kammer | Diagnostic and therapeutic use of ensandin-0138 gene and protein for neurodegenerative diseases |
AU2003301984A1 (en) * | 2002-05-15 | 2004-06-03 | Incyte Corporation | Vesicle-associated proteins |
ATE414789T1 (en) * | 2002-05-21 | 2008-12-15 | Mtm Lab Ag | MARKER FOR LUNG TUMORS |
US7339028B2 (en) * | 2002-06-06 | 2008-03-04 | The Trustees Of Columbia University In The City Of New York | Mahoganoid polypeptides, and related compositions and methods |
SG145559A1 (en) | 2002-06-06 | 2008-09-29 | Oncotherapy Science Inc | Genes and polypeptides relating to human colon cancers |
JP2005528913A (en) * | 2002-06-10 | 2005-09-29 | メルク エンド カムパニー インコーポレーテッド | Isolated nucleic acid molecules encoding novel centromere-related motor proteins and uses thereof |
AU2003276679A1 (en) * | 2002-06-13 | 2003-12-31 | Chiron Corporation | Vectors for expression of hml-2 polypeptides |
AU2003238032A1 (en) * | 2002-06-24 | 2004-01-06 | Bayer Healthcare Ag | Regulation of human growth hormone-releasing hormone receptor |
FR2841261B1 (en) * | 2002-06-25 | 2004-08-27 | Univ Pasteur | COMPOSITIONS AND METHODS FOR DETECTING PATHOLOGIES AFFECTING NEUROMUSCULAR TRANSMISSION |
WO2004001017A2 (en) * | 2002-06-25 | 2003-12-31 | Tao Biosciences, Llc | Methods for identifying antimicrobial agents, the agents identified therewith and methods of using same |
AU2003251008A1 (en) * | 2002-07-09 | 2004-01-23 | Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw | Diagnostic tests for the detection of peripheral neuropathy |
AU2003253930A1 (en) * | 2002-07-11 | 2004-02-02 | Seattle Genetics, Inc. | Sga-72m, a cancer associated antigen, and uses thereof |
CA2493061A1 (en) | 2002-07-16 | 2004-01-22 | Guangjie Cheng | Regulatory protein for nox enzymes |
EP1382613A1 (en) | 2002-07-16 | 2004-01-21 | Sumitomo Chemical Company, Limited | Novel G protein, polynucleotide encoding the same and utilization thereof |
GB0216661D0 (en) * | 2002-07-17 | 2002-08-28 | Ares Trading Sa | Protein |
US7135556B2 (en) | 2002-07-19 | 2006-11-14 | Schering Corporation | NPC1L1 (NPC3) and methods of use thereof |
US20040132058A1 (en) * | 2002-07-19 | 2004-07-08 | Schering Corporation | NPC1L1 (NPC3) and methods of use thereof |
US20050163821A1 (en) * | 2002-08-02 | 2005-07-28 | Hsing-Wen Sung | Drug-eluting Biodegradable Stent and Delivery Means |
US20050019404A1 (en) * | 2003-06-30 | 2005-01-27 | Hsing-Wen Sung | Drug-eluting biodegradable stent |
AU2003258056A1 (en) | 2002-08-07 | 2004-02-25 | Children's Medical Center Corporation | Sperm-specific cation channel, catsper-3, and uses therefor |
AU2003263981A1 (en) | 2002-08-07 | 2004-02-25 | Children's Medical Center Corporation | Sperm-specific cation channel, catsper-4, and uses therefor |
US7408048B2 (en) | 2002-08-09 | 2008-08-05 | Melbourne Health | Mammalian grainyhead transcription factors |
AU2003304034A1 (en) * | 2002-08-09 | 2004-11-01 | Curagen Corporation | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
WO2004016733A2 (en) | 2002-08-16 | 2004-02-26 | Agensys, Inc. | Nucleic acid and corresponding protein entitled 251p5g2 useful in treatment and detection of cancer |
AU2003282785A1 (en) * | 2002-08-26 | 2004-03-11 | Case Western Reserve University | Methods for treating patients and identifying therapeutics |
DE10242146A1 (en) | 2002-09-04 | 2004-03-18 | Eberhard-Karls-Universität Tübingen Universitätsklinikum | Antibodies for the identification and / or isolation of hematopoietic stem cells |
EP1575497A4 (en) * | 2002-09-11 | 2010-11-03 | Genentech Inc | Novel composition and methods for the treatment of psoriasis |
EP1398372A1 (en) * | 2002-09-13 | 2004-03-17 | Universitätsklinikum Charité an der Humboldt- Universität zu Berlin | Lipid phosphate phosphatases and uses thereof for treating neuronal diseases |
WO2004024914A1 (en) * | 2002-09-13 | 2004-03-25 | Sankyo Company, Limited | 2’,5’-oligoadenylate phosphodiesterase |
US6892925B2 (en) * | 2002-09-18 | 2005-05-17 | International Business Machines Corporation | Solder hierarchy for lead free solder joint |
US20060292668A1 (en) * | 2002-09-19 | 2006-12-28 | Zhengbin Yao | Nuclear factor of activated t cell receptor |
JP2006500074A (en) * | 2002-09-27 | 2006-01-05 | オリディス・ビオメド・フォルシュングス−ウント・エントヴィックルングス・ゲーエムベーハー | Polypeptides and nucleic acids encoding them and their use for prevention, diagnosis or treatment of liver damage and epithelial cancer |
TW200413725A (en) * | 2002-09-30 | 2004-08-01 | Oncotherapy Science Inc | Method for diagnosing non-small cell lung cancers |
AU2003279829A1 (en) * | 2002-10-04 | 2004-05-04 | Incyte Corp | Protein modification and maintenance molecules |
EP1559725A4 (en) * | 2002-10-04 | 2005-12-14 | Mitsubishi Pharma Corp | Antigen recognizing antibody |
EP1575518A4 (en) | 2002-10-10 | 2007-08-22 | Wyeth Corp | Compositions, organisms and methodologies employing a novel human kinase |
GB0224116D0 (en) * | 2002-10-16 | 2002-11-27 | Ares Trading Sa | Proteins |
WO2004038411A2 (en) * | 2002-10-24 | 2004-05-06 | Evotec Neurosciences Gmbh | Diagnostic and therapeutic use of ensadin-0289 gene and protein for neurodegenerative diseases |
EP1554385A2 (en) * | 2002-10-24 | 2005-07-20 | Wyeth | Calcineurin-like human phoshphoesterase |
EP1557178A4 (en) * | 2002-10-29 | 2009-07-22 | Takeda Pharmaceutical | Use of sglt homolog |
US7537914B1 (en) * | 2002-11-04 | 2009-05-26 | Florida State University Research Foundation, Inc. | Nucleic acid and allergenic polypeptides encoded thereby in cashew nuts (Anacardium occidentale) |
WO2004044205A1 (en) * | 2002-11-11 | 2004-05-27 | Korea Chungang Educational Foundation | Plant seed-specific expression promoter derived from sesame and seed-specific expression vector comprising the promoter |
NZ541504A (en) * | 2002-11-13 | 2009-04-30 | Uab Research Foundation | Synthetic single domain polypeptides mimicking apolipoprotein E and methods of use |
US7405289B2 (en) * | 2002-11-13 | 2008-07-29 | Metabolex, Inc. | Pancreatic islet transcription factor and uses thereof |
WO2004048521A2 (en) * | 2002-11-21 | 2004-06-10 | Wyeth | Composition and method for treating lupus nephritis |
DE10254601A1 (en) * | 2002-11-22 | 2004-06-03 | Ganymed Pharmaceuticals Ag | Gene products differentially expressed in tumors and their use |
EP1572975B1 (en) | 2002-11-26 | 2014-07-16 | University Of Tennessee Research Foundation | Streptococcus uberis adhesion molecule |
AU2003290664A1 (en) | 2002-11-27 | 2004-06-23 | Wei Liu | Compositions, organisms and methodologies employing a novel human kinase |
WO2004050702A2 (en) * | 2002-12-04 | 2004-06-17 | Applied Research Systems Ars Holding N.V. | Novel ifngamma-like polypeptides |
US6854636B2 (en) * | 2002-12-06 | 2005-02-15 | International Business Machines Corporation | Structure and method for lead free solder electronic package interconnections |
US7465581B2 (en) * | 2002-12-18 | 2008-12-16 | The Scripps Research Institute | ANKTM1, a cold-activated TRP-like channel expressed in nociceptive neurons |
US20050049214A1 (en) * | 2003-01-15 | 2005-03-03 | Chiron Corporation | Inhibition of E3-ubiquitin ligase HAKAI for treatment of proliferative disorders |
US7638270B2 (en) | 2003-01-24 | 2009-12-29 | Agensys, Inc. | Nucleic acids and corresponding proteins entitled 254P1D6B useful in treatment and detection of cancer |
AU2007231823B2 (en) * | 2003-01-24 | 2011-07-21 | Agensys, Inc. | Nucleic acids and corresponding proteins entitled 254P1D6B useful in treatment and detection of cancer |
US7304036B2 (en) | 2003-01-28 | 2007-12-04 | Microbia, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
WO2004069174A2 (en) * | 2003-01-31 | 2004-08-19 | Slil Biomedical Corporation | Monitoring and treatment of amyotrophic lateral sclerosis |
US7521534B1 (en) * | 2003-03-03 | 2009-04-21 | The University Board Of Regents Of Texas System | IKK gamma gene products and methods for making and using same |
EP1923400A1 (en) * | 2003-03-03 | 2008-05-21 | Genentech, Inc. | Compositions and methods for the treatment of systemic lupus erythematosis |
US7749695B2 (en) | 2003-03-03 | 2010-07-06 | Alexander Abbas | PRO polypeptides for diagnosis of systemic lupus erythematosis |
CA2518552A1 (en) * | 2003-03-11 | 2004-09-23 | Genentech, Inc. | Novel compositions and methods for the treatment of immune related disease |
EP1608983A2 (en) * | 2003-03-20 | 2005-12-28 | Novartis Forschungsstiftung, Zweigniederlassung Friedrich Miescher Institute for Biomedical Research | Materials and methods for modulating cell motility |
EP1464651A1 (en) * | 2003-04-03 | 2004-10-06 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Dystrophin-related protein (Drop1), a marker for carcinomas |
WO2004087748A1 (en) * | 2003-04-04 | 2004-10-14 | Centre National De La Recherche Scientifique | Protein with fusogenic activity, nucleic acid sequences encoding said protein and pharmaceutical compositions comprising the same |
WO2004092213A1 (en) * | 2003-04-08 | 2004-10-28 | The Government Of The United States Of America As Represented By The Secretary, Department Of Healthand Human Services | Gene expressed in prostate cancer, methods and use thereof |
WO2004094651A2 (en) * | 2003-04-18 | 2004-11-04 | Five Prime Therapeutics, Inc. | Novel human polypeptides encoded by polynucleotides |
US20050032695A1 (en) * | 2003-05-30 | 2005-02-10 | Aventis Pharma Deutschland Gmbh | Method for alleviating pain using protein associated with MYC and related compounds, and assays for identifying such compounds |
US7696169B2 (en) | 2003-06-06 | 2010-04-13 | The Feinstein Institute For Medical Research | Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents |
FR2843753A1 (en) * | 2003-06-20 | 2004-02-27 | Gene Signal | Antisense nucleic molecule useful as inhibitor of angiogenesis in the treatment of angiogenic disorders, e.g., rheumatoid arthritis, atherosclerosis and endometriosis |
EP1636379A2 (en) * | 2003-06-26 | 2006-03-22 | Exonhit Therapeutics S.A. | Prostate specific genes and the use thereof as targets for prostate cancer therapy and diagnosis |
FR2857098B1 (en) * | 2003-07-04 | 2006-05-05 | Inst Nat Sante Rech Med | METHOD FOR THE EVIDENCE OF A MOLECULAR EVENT IN A CELL USING FLUORESCENT MARKER PROTEINS |
GB0315827D0 (en) * | 2003-07-05 | 2003-08-13 | Imp College Innovations Ltd | Methods |
WO2005049791A2 (en) * | 2003-07-14 | 2005-06-02 | The Uab Research Foundation | Identification of reagents for the diagnosis and study of francisella |
EP1507004A1 (en) * | 2003-08-14 | 2005-02-16 | DKFZ Deutsches Krebsforschungszentrum | Method to inhibit the propagation of an undesired cell population |
WO2005019255A1 (en) | 2003-08-25 | 2005-03-03 | Pieris Proteolab Ag | Muteins of tear lipocalin |
WO2005024011A2 (en) * | 2003-09-04 | 2005-03-17 | Applied Research Systems Ars Holding N.V. | Novel ubp8rp polypeptides and their use in the treatment of psoriasis |
US8283307B2 (en) | 2003-09-08 | 2012-10-09 | Merck Serono Sa | Treatment of fibrotic disease |
DE10341812A1 (en) * | 2003-09-10 | 2005-04-07 | Ganymed Pharmaceuticals Ag | Differentially expressed in tumors gene products and their use |
CA2538763C (en) | 2003-09-11 | 2015-05-05 | Critical Therapeutics, Inc. | Monoclonal antibodies against hmgb1 |
WO2005030953A1 (en) * | 2003-09-30 | 2005-04-07 | Daiichi Pharmaceutical Co., Ltd. | Tetrahydrofolate synthase gene |
EP1692260A2 (en) * | 2003-10-06 | 2006-08-23 | Centocor, Inc. | Hypoxia - responsive human cngh-0002 genes and polypeptides |
US7985401B2 (en) | 2003-10-31 | 2011-07-26 | The Regents Of The University Of California | Peptides whose uptake by cells is controllable |
US7431915B2 (en) * | 2003-10-31 | 2008-10-07 | The Regents Of The University Of California | Peptides whose uptake by cells is controllable |
WO2005051981A1 (en) * | 2003-11-19 | 2005-06-09 | Pepharm R & D Limited | Biologically active peptides comprising isoleucyl-valyl-threonyl-asparaginyl-threonyl-threonine (ivtntt) |
WO2005051994A2 (en) * | 2003-11-21 | 2005-06-09 | Zymogenetics, Inc. | Ztnf11, a tumor necrosis factor |
NZ547629A (en) * | 2003-11-26 | 2009-08-28 | Max Planck Gesellschaft | Antibodies binding to conformationally discriminating epitopes of human IGG Fc receptor IIb and IIb |
CA2549710A1 (en) * | 2003-12-15 | 2005-06-23 | Genesis Research And Development Corporation Limited | Polynucleotides and polypeptides isolated from lactobacillus rhamnosus hn001 materials incorporating them and methods for using them |
GB0329958D0 (en) * | 2003-12-24 | 2004-01-28 | Univ Manchester | Treatment of viral infections |
CA2553769C (en) | 2004-01-16 | 2011-01-04 | Merck & Co., Inc. | Npc1l1 (npc3) and methods of identifying ligands thereof |
US7785805B2 (en) | 2004-01-28 | 2010-08-31 | Exelixis, Inc. | MAN2As as modifiers of the IGFR pathway and methods of use |
US7148192B2 (en) * | 2004-01-29 | 2006-12-12 | Ebwe Pharma Ges. M.H. Nfg.Kg | Neuroprotective dietary supplement |
US20050255530A1 (en) * | 2004-02-06 | 2005-11-17 | Keefer Carol L | Identification and isolation of pluripotency determining factors |
GB0403142D0 (en) * | 2004-02-12 | 2004-03-17 | Ares Trading Sa | Protein |
US20050186577A1 (en) | 2004-02-20 | 2005-08-25 | Yixin Wang | Breast cancer prognostics |
CA2560066A1 (en) | 2004-03-01 | 2005-09-15 | The Cbr Institute For Biomedical Research, Inc. | Natural igm antibodies and inhibitors thereof |
US7166433B2 (en) * | 2004-03-03 | 2007-01-23 | The United States Of America As Represented By The Department Of Health And Human Services | Transductin-1 and transductin-2 and applications to hereditary deafness |
US20070254283A1 (en) * | 2004-03-04 | 2007-11-01 | Roy Deudutta | Brhf1 as a Cancer Diagnostic Marker |
US20080050315A1 (en) * | 2004-03-24 | 2008-02-28 | Stefan Golz | Diagnostics and Therapeutics for Diseases Associated with Protein Kinase, Cgmp-Dependent, Type I (Prkg1) |
WO2005098440A2 (en) * | 2004-03-26 | 2005-10-20 | Immusol, Inc. | Methods for identifying agents useful for the treatment of neurodegenerative diseases |
EP1733743A4 (en) | 2004-04-09 | 2007-06-27 | Takeda Pharmaceutical | Preventives/remedies for cancer |
WO2005108563A2 (en) * | 2004-04-19 | 2005-11-17 | University Of Chicago | Peptidoglycan-hydrolyzing protein encoded by bacteriophage n4 |
BRPI0418766B8 (en) | 2004-04-22 | 2021-05-25 | Agensys Inc | antibody or fragment thereof, vector, pharmaceutical composition, assay and method for detecting the presence of step-1 protein, as well as a method for delivering a cytotoxic agent or a diagnostic agent |
CA2504920C (en) | 2004-05-14 | 2014-04-01 | Euroscreen S.A. | Ligand for g-protein coupled receptor fprl2 and uses thereof |
DE102004024617A1 (en) | 2004-05-18 | 2005-12-29 | Ganymed Pharmaceuticals Ag | Differentially expressed in tumors gene products and their use |
JP4649575B2 (en) * | 2004-05-19 | 2011-03-09 | 財団法人ヒューマンサイエンス振興財団 | Diagnosis of novel mucin genes and mucosal-related diseases |
WO2005114200A1 (en) * | 2004-05-21 | 2005-12-01 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with g protein-coupled receptor kinase 7 (grk7) |
DK2031063T3 (en) | 2004-06-18 | 2014-01-27 | Univ Duke | Modulators of fragrance receptors |
CA2559760A1 (en) * | 2004-07-02 | 2006-07-06 | Metanomics Gmbh | Process for the production of fine chemicals |
EP2287310B1 (en) * | 2004-07-22 | 2015-05-06 | Five Prime Therapeutics, Inc. | Compositions and methods using MGD-CSF in disease treatment |
WO2006022689A1 (en) * | 2004-08-06 | 2006-03-02 | Applera Corporation | Method and compositions for treating diseases targeting cd51 |
US8435507B2 (en) | 2004-08-19 | 2013-05-07 | University Of Maryland | Prostate-specific antigen-derived MHC class II restricted peptides and their use in vaccines to treat or prevent prostate cancer |
JP2008512120A (en) * | 2004-09-08 | 2008-04-24 | ルードヴィッヒ インスティテュート フォー キャンサー リサーチ | Cancer-testis antigen |
EP2292753A1 (en) | 2004-09-24 | 2011-03-09 | Oncotherapy Science, Inc. | Method for diagnosing non-small cell lung cancers by tRNA-dihydrouridine synthase activity of URLC8 |
US9944713B2 (en) * | 2004-11-24 | 2018-04-17 | Medicinal Bioconvergence Research Center | Antibody specific to the AIMP2-DX2 |
CA2590180A1 (en) * | 2004-12-10 | 2006-06-15 | The Corporation Of The Trustees Of The Order Of The Sisters Of Mercy In Queensland | Binding partners of antibodies specific for dendritic cell antigens |
DE102004059781A1 (en) * | 2004-12-10 | 2006-06-22 | Sanofi-Aventis Deutschland Gmbh | Use of serum / glucocorticoid-regulated kinase |
PT1838733E (en) | 2004-12-21 | 2011-12-13 | Medimmune Ltd | Antibodies directed to angiopoietin-2 and uses thereof |
EP1851543A2 (en) | 2005-02-24 | 2007-11-07 | Compugen Ltd. | Novel diagnostic markers, especially for in vivo imaging, and assays and methods of use thereof |
AU2006230563B8 (en) | 2005-03-31 | 2010-06-17 | Agensys, Inc. | Antibodies and related molecules that bind to 161P2F10B proteins |
US8350009B2 (en) | 2005-03-31 | 2013-01-08 | Agensys, Inc. | Antibodies and related molecules that bind to 161P2F10B proteins |
WO2006111586A2 (en) * | 2005-04-20 | 2006-10-26 | Proyecto De Biomedicina Cima, S.L. | Method for the in vitro determination of the degree of methylation of the line-1 promoter |
AU2006248201A1 (en) * | 2005-05-19 | 2006-11-23 | Synergenz Bioscience Limited | Methods for the assesssment of risk of developing lung cancer using analysis of genetic polymorphisms |
CA2608158A1 (en) * | 2005-05-19 | 2006-11-23 | Synergenz Bioscience Limited | Methods and compositions for assessment of pulmonary function and disorders |
AU2006248189A1 (en) * | 2005-05-20 | 2006-11-23 | Synergenz Bioscience Limited | Methods of analysis of polymorphisms and uses thereof |
AU2006284716B2 (en) * | 2005-09-01 | 2012-02-09 | The Feinstein Institute For Medical Research | Peptide mimics of melanocyte stimulating hormone |
US7659252B2 (en) | 2005-09-15 | 2010-02-09 | Novomed Technologies, Inc. (Shanghai) | Transdermal delivery peptides and method of use thereof |
WO2007035474A2 (en) * | 2005-09-15 | 2007-03-29 | Novomed Technologies, Inc. (Shanghai) | Transdermal delivery peptides and method of use thereof |
WO2007053803A2 (en) * | 2005-10-31 | 2007-05-10 | Centocor, Inc. | Antagonist of teb4 and methods of use |
EP1790664A1 (en) | 2005-11-24 | 2007-05-30 | Ganymed Pharmaceuticals AG | Monoclonal antibodies against claudin-18 for treatment of cancer |
US20070186295A1 (en) * | 2006-01-25 | 2007-08-09 | Daniel Chelsky | TAT-036 and methods of assessing and treating cancer |
BRPI0706784A2 (en) * | 2006-01-30 | 2011-04-05 | Ludwig Inst Cancer Res | testis cancer antigen ctsp |
WO2007090194A2 (en) * | 2006-02-01 | 2007-08-09 | The Burnham Institute For Medical Research | Lymphatic zip codes in tumors and pre-malignant lesions |
CN107446033B (en) * | 2006-02-22 | 2022-04-01 | 朱正崙 | Treatment of developmental related disorders |
WO2007100807A2 (en) | 2006-02-24 | 2007-09-07 | Schering Corporation | Npc1l1 orthologues |
WO2007104511A1 (en) * | 2006-03-13 | 2007-09-20 | Mubio Products Bv | Cancer vaccine |
US7811787B2 (en) * | 2006-04-25 | 2010-10-12 | Bristol-Myers Squibb Company | Polynucleotides encoding human SLAP-2 variant, hSLAP-2v3 |
EP2502628B1 (en) * | 2006-06-23 | 2016-12-14 | Alethia Biotherapeutics Inc. | Polynucleotides and polypeptide sequences involved in cancer |
KR20090064378A (en) * | 2006-08-10 | 2009-06-18 | 온코세라피 사이언스 가부시키가이샤 | Genes and polypeptides relating breast cancers |
EP2695896B1 (en) | 2006-10-06 | 2018-08-22 | The Government of the United States of America as represented by the Secretary of the Department of Health and Human Services | Prevention of tissue ischemia, related methods and compositions |
PT2502938E (en) | 2006-10-27 | 2015-06-05 | Genentech Inc | Antibodies and immunoconjugates and uses therefor |
EP2052085B1 (en) * | 2006-12-21 | 2019-05-22 | Cognosci, Inc. | Methods for modulating set and uses thereof |
US8309687B2 (en) * | 2007-03-15 | 2012-11-13 | Reverse Proteomics Research Institute Co., Ltd. | Biomarker specific for cancer |
WO2008121007A1 (en) * | 2007-03-29 | 2008-10-09 | Auckland Uniservices Limited | Novel saratan polypeptides and polynucleotides and methods of use thereof |
WO2008126517A1 (en) * | 2007-03-30 | 2008-10-23 | National University Corporation Okayama University | Novel slc17-type transporter protein in mammal and use thereof |
US20100249038A1 (en) * | 2007-06-12 | 2010-09-30 | Board Of Regents, University Of Texas System | Antagonists of the receptor for advanced glycation end-products (rage) |
FR2919616A1 (en) * | 2007-08-02 | 2009-02-06 | Ecole Norm Superieure Lyon | INSULATORY POLYNUCLEOTIDES DERIVED FROM THE D4Z4 ELEMENT AND THEIR USES IN TRANSGENESIS |
US8163874B2 (en) * | 2007-08-06 | 2012-04-24 | The United States Of America, As Represented By The Secretary Of The Navy | Beta helical peptide structures stable in aqueous and non-aqueous media and methods for preparing same |
CN103483424A (en) * | 2007-08-09 | 2014-01-01 | 诺瓦提斯公司 | Thiopeptide precursor protein, gene encoding it and uses thereof |
EP3492488A1 (en) | 2007-08-22 | 2019-06-05 | The Regents of The University of California | Activatable binding polypeptides and methods of identification and use thereof |
CA2695559A1 (en) * | 2007-08-24 | 2009-03-05 | Ramot At Tel-Aviv University, Ltd. | Neuroprotection using nap-like and sal-like peptide mimetics |
AU2008296478B9 (en) | 2007-08-28 | 2015-03-19 | The Uab Research Foundation | Synthetic apolipoprotein E mimicking polypeptides and methods of use |
DE102007041657A1 (en) * | 2007-09-03 | 2009-03-05 | Protagen Ag | Marker sequences for multiple sclerosis and their use |
US8450279B2 (en) * | 2007-09-04 | 2013-05-28 | Procell Therapeutics Inc. | Cell permeable Nm23 recombinant proteins, polynucleotides encoding the same, and anti-metastatic composition comprising the same |
EP2198306A1 (en) | 2007-09-06 | 2010-06-23 | Case Western Reserve University | Methods for diagnosing and treating cancers |
WO2009039188A1 (en) * | 2007-09-17 | 2009-03-26 | Ludwig Institute For Cancer Research Ltd | Peptides and methods for the treatment of gliomas and other cancers |
AU2008301888A1 (en) * | 2007-09-20 | 2009-03-26 | R. Bradley Jones | Long interspersed nuclear element polypeptide compositions and methods of use thereof |
GB0719367D0 (en) | 2007-10-03 | 2007-11-14 | Procarta Biosystems Ltd | Transcription factor decoys, compositions and methods |
JP2011521626A (en) * | 2008-05-02 | 2011-07-28 | エピセンター テクノロジーズ コーポレーション | RNA polyphosphatase compositions, kits and uses thereof |
US8324165B2 (en) | 2008-05-14 | 2012-12-04 | Five Prime Therapeutics, Inc. | Compositions for treating arthritis comprising HG1023575 polypeptide |
US9051574B2 (en) * | 2008-06-03 | 2015-06-09 | University Of Maryland, Baltimore | Non-hemolytic ClyA for excretion of proteins |
CN102066945A (en) * | 2008-06-19 | 2011-05-18 | 科技研究局 | Modulators of STAT3 signalling |
EP2324048A2 (en) * | 2008-07-30 | 2011-05-25 | Cosmix Therapeutics Llc | Peptide therapeutics that bind vegf and methods of use thereof |
EP2172477A1 (en) * | 2008-10-06 | 2010-04-07 | Atlas Antibodies AB | Epitopes derived from SATB2 and uses thereof |
US8156130B2 (en) | 2008-10-17 | 2012-04-10 | Embarq Holdings Company Llc | System and method for collapsing search results |
US8874564B2 (en) * | 2008-10-17 | 2014-10-28 | Centurylink Intellectual Property Llc | System and method for communicating search results to one or more other parties |
US8326829B2 (en) * | 2008-10-17 | 2012-12-04 | Centurylink Intellectual Property Llc | System and method for displaying publication dates for search results |
WO2010048125A2 (en) * | 2008-10-22 | 2010-04-29 | Trustees Of Dartmouth College | Compositions and methods for inhibiting the interaction between cftr and cal |
US9421239B2 (en) | 2008-10-22 | 2016-08-23 | Trustees Of Dartmouth College | Therapy and kit for the prevention and treatment of cystic fibrosis |
US9333235B2 (en) | 2008-10-22 | 2016-05-10 | Trustees Of Dartmouth College | Combination therapy and kit for the prevention and treatment of cystic fibrosis |
US8999919B2 (en) | 2008-10-22 | 2015-04-07 | Trustees Of Dartmouth College | Compositions and methods for inhibiting the interaction between CFTR and CAL |
EP2342355A4 (en) * | 2008-10-29 | 2012-06-27 | Beaumont Hospital William | Methods of using biomarkers |
CA2739705A1 (en) * | 2008-10-30 | 2010-05-06 | Yissum Research Development Company Of The Hebrew University Of Jerusale M Ltd. | Efficient expression of truncated human rnaset2 in e. coli |
US9855291B2 (en) | 2008-11-03 | 2018-01-02 | Adc Therapeutics Sa | Anti-kidney associated antigen 1 (KAAG1) antibodies |
US20110286924A1 (en) * | 2008-12-09 | 2011-11-24 | Alethia Biotherapeutics Inc | Novel human endogenous retroviral erv3 variant and uses thereof in the diagnosing ovarian cancer |
BRPI1006141B8 (en) * | 2009-01-12 | 2021-05-25 | Cytomx Therapeutics Llc | modified antibody compositions, methods of making and using the same |
CA2753294A1 (en) | 2009-02-23 | 2010-08-26 | Cytomx Therapeutics, Inc. | Proproteins and methods of use thereof |
CN102333543B (en) * | 2009-02-24 | 2014-05-14 | 国立大学法人宫崎大学 | Cell adhesion inhibitor and use thereof |
EP2403864B1 (en) | 2009-02-27 | 2015-08-12 | Atyr Pharma, Inc. | Polypeptide structural motifs associated with cell signaling activity |
US8404242B2 (en) | 2009-03-16 | 2013-03-26 | Atyr Pharma, Inc. | Compositions and methods comprising histidyl-tRNA synthetase splice variants having non-canonical biological activities |
PL2408913T3 (en) | 2009-03-18 | 2017-07-31 | Oncotherapy Science, Inc. | Neil3 peptides and vaccines including the same |
WO2010120509A2 (en) | 2009-03-31 | 2010-10-21 | Atyr Pharma, Inc. | Compositions and methods comprising aspartyl-trna synthetases having non-canonical biological activities |
WO2010118324A2 (en) | 2009-04-09 | 2010-10-14 | Nuclea Biotechnologies, LLC | Antibodies against fatty acid synthase |
CA2767570C (en) | 2009-07-13 | 2018-05-01 | Universite De Montreal | Mutated sumo isoforms and uses thereof |
JP2012533560A (en) | 2009-07-15 | 2012-12-27 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | Peptides that can control uptake in cells |
WO2011031517A1 (en) | 2009-08-27 | 2011-03-17 | Nuclea Biotechnologies, LLC | Method and assay for determining fas expression |
KR101854820B1 (en) * | 2009-09-25 | 2018-05-04 | 샤이어 오펀 테라피즈 게엠베하 | Novel NPR-B Agonists |
WO2011038066A2 (en) * | 2009-09-25 | 2011-03-31 | Alcon Research, Ltd. | Novel npr-b agonists |
WO2011040417A1 (en) * | 2009-09-29 | 2011-04-07 | 学校法人福岡大学 | Inositol-1,4,5-trisphosphate receptor binding protein, and transgenic non-human mammal containing same |
DK2509625T3 (en) | 2009-12-11 | 2015-04-27 | Atyr Pharma Inc | Histidyl tRNA synthetases to reduce inflammation |
WO2011072266A2 (en) * | 2009-12-11 | 2011-06-16 | Atyr Pharma, Inc. | Aminoacyl trna synthetases for modulating hematopoiesis |
US8828395B2 (en) | 2009-12-11 | 2014-09-09 | Atyr Pharma, Inc. | Antibodies that bind tyrosyl-tRNA synthetases |
US9023802B2 (en) * | 2009-12-14 | 2015-05-05 | Immatics Biotechnologies Gmbh | HLA-binding peptides derived from prostate-associated antigenic molecules and methods of use thereof |
TW201121995A (en) | 2009-12-18 | 2011-07-01 | Alcon Res Ltd | Novel NPR-B agonists |
PL2530091T3 (en) | 2010-01-29 | 2018-08-31 | Chugai Seiyaku Kabushiki Kaisha | Anti-dll3 antibody |
AU2011213609B2 (en) | 2010-02-08 | 2016-11-03 | Agensys, Inc. | Antibody drug conjugates (ADC) that bind to 161P2F10B proteins |
GB201002413D0 (en) | 2010-02-12 | 2010-03-31 | Procarta Biosystems Ltd | Nucleic acid complexes |
JP5655254B2 (en) * | 2010-02-16 | 2015-01-21 | 国立大学法人京都工芸繊維大学 | Polycarbonate and / or polymethyl methacrylate affinity peptide and use thereof |
GB201005545D0 (en) | 2010-04-01 | 2010-05-19 | Procarta Biosystems Ltd | Transcription factor decoys |
JP6066900B2 (en) | 2010-04-26 | 2017-01-25 | エータイアー ファーマ, インコーポレイテッド | Innovative discovery of therapeutic, diagnostic and antibody compositions related to protein fragments of cysteinyl tRNA synthetase |
AU2011248614B2 (en) | 2010-04-27 | 2017-02-16 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of isoleucyl tRNA synthetases |
CA2797259C (en) | 2010-04-27 | 2020-09-29 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of threonyl trna synthetases |
CA2797271C (en) | 2010-04-28 | 2021-05-25 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of alanyl trna synthetases |
EP2563383B1 (en) | 2010-04-29 | 2017-03-01 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of valyl trna synthetases |
WO2011139854A2 (en) | 2010-04-29 | 2011-11-10 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of asparaginyl trna synthetases |
CN103108655B (en) | 2010-05-03 | 2017-04-05 | Atyr 医药公司 | Treatment, diagnosis and the innovation of antibody compositions related to the protein fragments of seryl tRNA synzyme finds |
US9034321B2 (en) | 2010-05-03 | 2015-05-19 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of phenylalanyl-alpha-tRNA synthetases |
CA2797277C (en) | 2010-05-03 | 2021-02-23 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of arginyl-trna synthetases |
CN103140233B (en) | 2010-05-03 | 2017-04-05 | Atyr 医药公司 | Treatment, diagnosis and the discovery of antibody compositions related to the protein fragments of methionyl-tRNA synthetase |
JP6008843B2 (en) | 2010-05-04 | 2016-10-19 | エータイアー ファーマ, インコーポレイテッド | Innovative discovery of therapeutic, diagnostic and antibody compositions related to protein fragments of glutamyl-prolyl tRNA synthetase |
CN102985103A (en) | 2010-05-04 | 2013-03-20 | Atyr医药公司 | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of p38 multi-tRNA synthetase complex |
JP6396656B2 (en) | 2010-05-14 | 2018-09-26 | エータイアー ファーマ, インコーポレイテッド | Innovative discovery of therapeutic, diagnostic and antibody compositions related to protein fragments of phenylalanyl βtRNA synthetase |
US9034598B2 (en) | 2010-05-17 | 2015-05-19 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of leucyl-tRNA synthetases |
WO2011146942A1 (en) * | 2010-05-21 | 2011-11-24 | The Translational Genomics Research Institute | Methods and kits to analyze microrna by nucleic acid sequencing |
CN103096913B (en) | 2010-05-27 | 2017-07-18 | Atyr 医药公司 | Treatment, diagnosis and the innovation of antibody compositions related to the protein fragments of glutaminyl tRNA synzyme is found |
RU2012157597A (en) | 2010-05-31 | 2014-07-20 | Лондон Хелс Сайенсис Сентр Рисерч Инк. | RHAMM-BINDING PEPTIDES |
AU2011261486B2 (en) | 2010-06-01 | 2017-02-23 | Pangu Biopharma Limited | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of lysyl-tRNA synthetases |
CN103108649B (en) | 2010-07-12 | 2016-10-12 | Atyr医药公司 | Treatment, diagnosis and the antibody compositions relevant to the protein fragments of Jo-1 |
US8969301B2 (en) | 2010-07-12 | 2015-03-03 | Atyr Pharma Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of aspartyl-tRNA synthetases |
US8999321B2 (en) | 2010-07-12 | 2015-04-07 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic, and antibody compositions related to protein fragments of glycyl-tRNA synthetases |
JP6116479B2 (en) | 2010-07-12 | 2017-04-19 | エータイアー ファーマ, インコーポレイテッド | Innovative discovery of therapeutic, diagnostic and antibody compositions related to protein fragments of glycyl-tRNA synthetase |
US10865445B2 (en) * | 2010-08-18 | 2020-12-15 | Fred Hutchinson Cancer Research Center | Methods for alleviating facioscapulohumeral dystrophy (FSHD) by N siRNA molecule inhibiting the expression of DUX4-FL |
WO2012027611A2 (en) | 2010-08-25 | 2012-03-01 | Atyr Pharma, Inc. | INNOVATIVE DISCOVERY OF THERAPEUTIC, DIAGNOSTIC, AND ANTIBODY COMPOSITIONS RELATED TO PROTEIN FRAGMENTS OF TYROSYL-tRNA SYNTHETASES |
CA2812644A1 (en) | 2010-09-27 | 2012-04-05 | Zestagen, S.A. | Compositions and methods for treating neoplasia |
TWI764324B (en) | 2010-09-29 | 2022-05-11 | 美商艾澤西公司 | Antibody drug conjugates (adc) that bind to 191p4d12 proteins |
ES2645019T3 (en) | 2010-10-06 | 2017-12-01 | Atyr Pharma, Inc. | Innovative discovery of therapeutic, diagnostic and antibody compositions related to tryptophanil-tRNA synthetases protein fragments |
KR20130126671A (en) * | 2010-12-14 | 2013-11-20 | 이매틱스 바이오테크놀로지스 게엠베하 | Hla-binding peptides derived from prostate-associated antigenic molecules and methods of use thereof |
WO2012112842A2 (en) | 2011-02-17 | 2012-08-23 | The Government Of The United States Of America, As Represented By The Secretary, Department Of Health & Human Services | Compositions and methods for treating poliovirus |
US10370417B2 (en) | 2011-03-01 | 2019-08-06 | Rutgers, The State University Of New Jersey | Methods for the diagnosis of cancer through detection of human endogenous retrovirus WL (HERV-WL) envelope expression |
WO2012118974A2 (en) * | 2011-03-01 | 2012-09-07 | University Of Medicine And Dentistry Of New Jersey | Detection of human endogenous retrovirus expression in cancer and normal cells |
AU2012234754B2 (en) | 2011-03-31 | 2016-09-29 | Adc Therapeutics Sa | Antibodies against kidney associated antigen 1 and antigen binding fragments thereof |
EP2511295A1 (en) * | 2011-04-15 | 2012-10-17 | Institut National De La Sante Et De La Recherche Medicale | Compositions for preventing and/or treating an infection by an HIV-1 virus |
US10654916B2 (en) | 2011-04-21 | 2020-05-19 | The Regents Of The University Of California, A California Corporation | Compositions and methods for the treatment of neuromyelitis optica |
CA2841249C (en) | 2011-07-29 | 2023-09-26 | Avelas Biosciences, Inc. | Selective delivery molecules and methods of use |
US9714419B2 (en) | 2011-08-09 | 2017-07-25 | Atyr Pharma, Inc. | PEGylated tyrosyl-tRNA synthetase polypeptides |
SG10201601840RA (en) * | 2011-09-09 | 2016-04-28 | Agency Science Tech & Res | P53 activating peptides |
US20130084582A1 (en) | 2011-10-04 | 2013-04-04 | Err-Cheng Chan | Serological markers for detecting colorectal cancer and their application for inhibiting colorectal cancer cells |
JP2014532408A (en) * | 2011-10-26 | 2014-12-08 | ニュークレア バイオテクノロジーズ インコーポレイテッドNuclea Biotechnologies,Inc. | USP2a peptide and antibody |
WO2013086216A1 (en) | 2011-12-06 | 2013-06-13 | Atyr Pharma, Inc. | Improved aspartyl-trna synthetases |
US9822353B2 (en) | 2011-12-06 | 2017-11-21 | Atyr Pharma, Inc. | PEGylated aspartyl-tRNA synthetase polypeptides |
AU2012368189B2 (en) | 2011-12-29 | 2017-08-31 | Atyr Pharma, Inc. | Aspartyl-tRNA synthetase-Fc conjugates |
JP6282597B2 (en) | 2012-01-09 | 2018-02-21 | アー・デー・ツェー・セラピューティクス・エス・アー | How to treat breast cancer |
WO2013123432A2 (en) | 2012-02-16 | 2013-08-22 | Atyr Pharma, Inc. | Histidyl-trna synthetases for treating autoimmune and inflammatory diseases |
WO2013167153A1 (en) | 2012-05-09 | 2013-11-14 | Ganymed Pharmaceuticals Ag | Antibodies useful in cancer diagnosis |
WO2013174404A1 (en) | 2012-05-23 | 2013-11-28 | Ganymed Pharmaceuticals Ag | Combination therapy involving antibodies against claudin 18.2 for treatment of cancer |
EP3971571A3 (en) | 2012-05-25 | 2022-06-08 | The University of Vermont and State Agriculture College | Compositions and methods for assaying platelet reactivity and treatment selection |
EP2861622A4 (en) | 2012-06-15 | 2016-06-01 | Sinomab Bioscience Ltd | Anti-cd22 anti-idiotypic antibodies and uses thereof |
US9957557B2 (en) * | 2012-08-13 | 2018-05-01 | Life Genetics Lab, Llc | Development of a highly sensitive quantification system for assessing DNA degradation and quality in forensic samples |
KR20240033145A (en) | 2012-11-13 | 2024-03-12 | 비온테크 에스이 | Agents for treatment of claudin expressing cancer diseases |
WO2014120837A2 (en) | 2013-01-29 | 2014-08-07 | The Regents Of The University Of California | Pretargeted activatable cell penetrating peptide with intracellulary releaseable prodrug |
CN105102484B (en) | 2013-01-30 | 2020-03-10 | 艾维拉斯生物科学公司 | Selective delivery molecules and methods of use |
WO2014127785A1 (en) | 2013-02-20 | 2014-08-28 | Ganymed Pharmaceuticals Ag | Combination therapy involving antibodies against claudin 18.2 for treatment of cancer |
KR20210108497A (en) | 2013-02-26 | 2021-09-02 | 메모리얼 슬로안 케터링 캔서 센터 | Compositions and methods for immunotherapy |
US9409977B2 (en) | 2013-03-12 | 2016-08-09 | Decimmune Therapeutics, Inc. | Humanized, anti-N2 antibodies |
US10295547B2 (en) | 2013-03-14 | 2019-05-21 | University Of Florida Research Foundation, Incorporated | Use and treatment of di-amino acid repeat-containing proteins associated with ALS |
IL300508A (en) | 2013-03-15 | 2023-04-01 | Memorial Sloan Kettering Cancer Center | Compositions and methods for immunotherapy |
US9587235B2 (en) | 2013-03-15 | 2017-03-07 | Atyr Pharma, Inc. | Histidyl-tRNA synthetase-Fc conjugates |
WO2014146672A1 (en) | 2013-03-18 | 2014-09-25 | Ganymed Pharmaceuticals Ag | Therapy involving antibodies against claudin 18.2 for treatment of cancer |
EP2981607B1 (en) | 2013-04-03 | 2020-08-19 | Memorial Sloan Kettering Cancer Center | Effective generation of tumor-targeted t-cells derived from pluripotent stem cells |
EP2999710B1 (en) * | 2013-05-20 | 2019-10-02 | Nanyang Technological University | Peptides binding to parallel-stranded g-quadruplexes |
KR101841211B1 (en) * | 2014-03-10 | 2018-03-22 | 한양대학교 산학협력단 | Cell penetrating peptide and method for delivery of biologically active materials using it |
WO2015176010A1 (en) | 2014-05-15 | 2015-11-19 | The United States Of America, As Represented By The Secretary, Departmentof Health & Human Services | Treatment or prevention of an intestinal disease or disorder |
WO2015188141A2 (en) | 2014-06-06 | 2015-12-10 | Memorial Sloan-Kettering Cancer Ceneter | Mesothelin-targeted chimeric antigen receptors and uses thereof |
US10653747B2 (en) | 2014-07-31 | 2020-05-19 | Uab Research Foundation | ApoE mimetic peptides and higher potency to clear plasma cholesterol |
WO2016022597A1 (en) * | 2014-08-04 | 2016-02-11 | Case Western Reserve University | Targeting peptides and methods of use |
US10925980B2 (en) | 2014-08-04 | 2021-02-23 | Case Western Reserve University | Molecular probes and methods of use |
CN107002046B (en) | 2014-08-25 | 2021-05-11 | 经纬生物科技有限公司 | Non-replicating transduction particles and transduction particle-based reporter systems |
US10385380B2 (en) | 2014-10-02 | 2019-08-20 | The Regents Of The University Of California | Personalized protease assay to measure protease activity in neoplasms |
KR101693431B1 (en) | 2014-11-18 | 2017-01-06 | 울산대학교 산학협력단 | Targeting Peptides for Gastric Cancer and Medical Use Thereof |
CA2969870A1 (en) | 2014-12-05 | 2016-06-09 | Memorial Sloan-Kettering Cancer Center | Chimeric antigen receptors targeting b-cell maturation antigen and uses thereof |
MY195115A (en) | 2014-12-05 | 2023-01-10 | Memorial Sloan Kettering Cancer Center | Antibodies targeting g-protein coupled receptor and methods of use |
SI3226897T1 (en) | 2014-12-05 | 2021-08-31 | Memorial Sloan Kettering Cancer Center | Antibodies targeting b-cell maturation antigen and methods of use |
JP7174522B2 (en) | 2014-12-05 | 2022-11-17 | メモリアル スローン ケタリング キャンサー センター | Chimeric antigen receptor targeting Fc receptor-like 5 and uses thereof |
HRP20211978T1 (en) | 2014-12-05 | 2022-04-01 | Memorial Sloan-Kettering Cancer Center | Chimeric antigen receptors targeting g-protein coupled receptor and uses thereof |
US10539572B2 (en) | 2015-01-30 | 2020-01-21 | Salk Institute For Biological Studies | Compositions and methods for treating age-related diabetes and related disorders |
US11497767B2 (en) | 2015-02-18 | 2022-11-15 | Enlivex Therapeutics R&D Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
US11318163B2 (en) | 2015-02-18 | 2022-05-03 | Enlivex Therapeutics Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
US11596652B2 (en) | 2015-02-18 | 2023-03-07 | Enlivex Therapeutics R&D Ltd | Early apoptotic cells for use in treating sepsis |
US11000548B2 (en) | 2015-02-18 | 2021-05-11 | Enlivex Therapeutics Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
US11304976B2 (en) | 2015-02-18 | 2022-04-19 | Enlivex Therapeutics Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
US11512289B2 (en) | 2015-02-18 | 2022-11-29 | Enlivex Therapeutics Rdo Ltd | Combination immune therapy and cytokine control therapy for cancer treatment |
EP3285877B1 (en) | 2015-04-21 | 2022-10-19 | Enlivex Therapeutics Rdo Ltd | Therapeutic pooled blood apoptotic cell preparations and uses thereof |
US10596259B2 (en) | 2015-05-20 | 2020-03-24 | The Regents Of The University Of California | Tumor radiosensitization with monomethyl auristatin E (MMAE) and derivatives thereof |
WO2016191263A1 (en) | 2015-05-22 | 2016-12-01 | Trustees Of Dartmouth College | Therapy and kit for the prevention and treatment of cystic fibrosis |
TW201702272A (en) | 2015-05-22 | 2017-01-16 | 美國紀念斯隆 凱特琳癌症中心 | T cell receptor-like antibodies specific for a PRAME peptide |
WO2016196324A1 (en) | 2015-05-29 | 2016-12-08 | University Of Floridia Research Foundation, Inc. | Methods for diagnosing huntington's disease |
GB201511546D0 (en) | 2015-07-01 | 2015-08-12 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers |
MA54884A (en) | 2015-07-01 | 2022-01-12 | Immatics Biotechnologies Gmbh | NEUARTIGE PEPTIDE UND KOMBINATION AUS PEPTIDEN ZUR VERWENDUNG IN DER IMMUNTHERAPIE GEGEN OVARIALKARZINOM UND ANDERE KARZINOME |
EP3328994A4 (en) | 2015-07-31 | 2019-04-17 | Memorial Sloan-Kettering Cancer Center | Antigen-binding proteins targeting cd56 and uses thereof |
CN115925806A (en) | 2015-08-28 | 2023-04-07 | 伊玛提克斯生物技术有限公司 | Novel peptides, peptide compositions and scaffolds for immunotherapy of various cancers |
GB201515321D0 (en) | 2015-08-28 | 2015-10-14 | Immatics Biotechnologies Gmbh | Novel peptides, combination of peptides and scaffolds for use in immunotherapeutic treatment of various cancers |
EP3341482B1 (en) * | 2015-08-28 | 2022-07-06 | CureVac AG | Artificial nucleic acid molecules |
WO2017040526A2 (en) * | 2015-09-01 | 2017-03-09 | Eisai R&D Management Co., Ltd. | Splice variants associated with neomorphic sf3b1 mutants |
CA2997551A1 (en) | 2015-09-04 | 2017-03-09 | Memorial Sloan Kettering Cancer Center | Immune cell compositions and methods of use |
EP3336098B1 (en) * | 2015-09-10 | 2021-08-11 | IUCF-HYU (Industry-University Cooperation Foundation Hanyang University) | Skin permeable peptide and method for using same |
AU2016362402A1 (en) | 2015-12-04 | 2018-06-28 | Eureka Therapeutics, Inc. | Antibodies targeting Fc receptor-like 5 and methods of use |
WO2017100428A1 (en) | 2015-12-09 | 2017-06-15 | Memorial Sloan Kettering Cancer Center | Immune cell compositions and methods of using same |
JP7022067B2 (en) | 2016-01-14 | 2022-02-17 | メモリアル スローン ケタリング キャンサー センター | T-cell receptor-like antibody specific for FOXP3-derived peptide |
CA3014885A1 (en) | 2016-02-18 | 2017-08-24 | Enlivex Therapeutics Ltd. | Combination immune therapy and cytokine control therapy for cancer treatment |
GB201604490D0 (en) | 2016-03-16 | 2016-04-27 | Immatics Biotechnologies Gmbh | Peptides combination of peptides for use in immunotherapy against cancers |
US10940161B2 (en) | 2016-04-04 | 2021-03-09 | University Of Florida Research Foundation, Incorporated | Manipulation of EIF3 to modulate repeat associated non-ATG (RAN) translation |
PT3443075T (en) | 2016-04-15 | 2022-12-16 | Memorial Sloan Kettering Cancer Center | Transgenic t cell and chimeric antigen receptor t cell compositions and related methods |
WO2017218949A2 (en) * | 2016-06-17 | 2017-12-21 | Aileron Therapeutics, Inc. | Peptidomimetic macrocycles and uses thereof |
US20180052169A1 (en) * | 2016-08-22 | 2018-02-22 | The Board Of Regents Of The University Of Texas System | Tsp1 as a marker for cancer |
CA3034691A1 (en) | 2016-08-30 | 2018-03-08 | Memorial Sloan Kettering Cancer Center | Immune cell compositions and methods of use for treating viral and other infections |
AU2017342555A1 (en) | 2016-10-14 | 2019-05-30 | Children's Medical Center Corporation | Compositions and methods for treating diseases and disorders of the central nervous system |
CA3042706A1 (en) | 2016-11-09 | 2018-05-17 | Intrexon Corporation | Frataxin expression constructs |
JP2020502056A (en) * | 2016-11-13 | 2020-01-23 | イマジン ファーマ | Compositions and methods for treating diabetes, hypertension and hypercholesterolemia |
GB201621737D0 (en) * | 2016-12-20 | 2017-02-01 | Aberystwyth Univ | Compositions and methods of treatment |
US11566060B2 (en) | 2017-01-05 | 2023-01-31 | Kahr Medical Ltd. | PD1-CD70 fusion protein and methods of use thereof |
US11299530B2 (en) | 2017-01-05 | 2022-04-12 | Kahr Medical Ltd. | SIRP alpha-CD70 fusion protein and methods of use thereof |
HRP20220230T1 (en) | 2017-01-05 | 2022-04-29 | Kahr Medical Ltd. | A sirp1 alpha-41bbl fusion protein and methods of use thereof |
DK3565579T3 (en) | 2017-01-05 | 2023-09-04 | Kahr Medical Ltd | PD1-41BBL FUSION PROTEIN AND METHODS OF USING THEREOF |
AU2018210853B2 (en) | 2017-01-17 | 2023-09-28 | Children's Medical Center Corporation | Compositions and methods for treating lysosomal storage diseases and disorders |
EP3576781B9 (en) | 2017-01-18 | 2024-03-06 | Icahn School of Medicine at Mount Sinai | Neoantigens and uses thereof for treating cancer |
US11260101B2 (en) * | 2017-02-28 | 2022-03-01 | Jinan University | Repair peptide for use in promoting post-traumatic tissue repair and regeneration, and application thereof |
AU2018231190B2 (en) | 2017-03-08 | 2023-05-25 | Memorial Sloan Kettering Cancer Center | Immune cell compositions and methods of use |
ES2955852T3 (en) | 2017-04-03 | 2023-12-07 | Hoffmann La Roche | STEAP-1 binding antibodies |
JP2020516674A (en) | 2017-04-17 | 2020-06-11 | ユニバーシティー オブ フロリダ リサーチ ファンデーション, インク. | Regulation of RAN protein translation by the PKR and eIF2A-P pathways |
EP3612215A4 (en) | 2017-04-20 | 2021-05-26 | aTyr Pharma, Inc. | Compositions and methods for treating lung inflammation |
SG11201910101SA (en) | 2017-05-08 | 2019-11-28 | Gritstone Oncology Inc | Alphavirus neoantigen vectors |
CA3063464A1 (en) * | 2017-05-19 | 2018-11-22 | Encoded Therapeutics, Inc. | High activity regulatory elements |
WO2019067587A1 (en) | 2017-09-26 | 2019-04-04 | University Of Florida Research Foundation, Incorporated | Use of metformin and analogs thereof to reduce ran protein levels in the treatment of neurological disorders |
WO2019067592A1 (en) | 2017-09-27 | 2019-04-04 | University Of Georgia Research Foundation | Treatment and detection of infection and disease associated with different fungal pathogens |
AU2018367452A1 (en) | 2017-11-14 | 2020-06-11 | Memorial Sloan-Kettering Cancer Center | IL-36 secreting immunoresponsive cells and uses thereof |
US11008602B2 (en) | 2017-12-20 | 2021-05-18 | Roche Molecular Systems, Inc. | Non-replicative transduction particles and transduction particle-based reporter systems |
TWI817974B (en) | 2017-12-28 | 2023-10-11 | 日商中外製藥股份有限公司 | Cytotoxicity-inducing therapeutic agent |
JP7416695B2 (en) | 2017-12-29 | 2024-01-17 | メモリアル スローン-ケタリング キャンサー センター | Enhanced chimeric antigen receptors and their uses |
BR112020013679A2 (en) | 2018-01-04 | 2020-12-01 | Iconic Therapeutics, Inc. | antitecid factor antibodies, antibody-drug conjugates and related methods |
CA3081125A1 (en) | 2018-02-01 | 2019-08-08 | Innovent Biologics (Suzhou) Co., Ltd. | Fully humanized anti-b cell maturation antigen (bcma) single-chain antibody and use thereof |
KR20200120673A (en) | 2018-02-11 | 2020-10-21 | 메모리얼 슬로안 케터링 캔서 센터 | Non-HLA restricted T cell receptor and uses thereof |
CA3091143A1 (en) | 2018-02-15 | 2019-08-22 | Memorial Sloan-Kettering Cancer Center | Foxp3 targeting agent compositions and methods of use for adoptive cell therapy |
EP3740247A4 (en) | 2018-03-02 | 2022-06-08 | Dicerna Pharmaceuticals, Inc. | Compositions and methods for inhibiting gys2 expression |
SG11202013167UA (en) | 2018-07-11 | 2021-01-28 | Kahr Medical Ltd | SIRPalpha-4-1BBL VARIANT FUSION PROTEIN AND METHODS OF USE THEREOF |
EP3880714A4 (en) | 2018-11-16 | 2022-07-20 | Memorial Sloan Kettering Cancer Center | Antibodies to mucin-16 and methods of use thereof |
EP3947471A4 (en) | 2019-03-27 | 2023-03-15 | The Trustees of The University of Pennsylvania | Tn-muc1 chimeric antigen receptor (car) t cell therapy |
CN110256574B (en) * | 2019-05-21 | 2020-12-04 | 山东大学 | Fusion polypeptide and application thereof in preparing medicament for resisting depression and neurodegenerative diseases |
KR20220016137A (en) | 2019-05-30 | 2022-02-08 | 그릿스톤 바이오, 인코포레이티드 | modified adenovirus |
EP4041745A4 (en) * | 2019-10-08 | 2024-02-07 | Univ North Carolina State | Immunoglobulin purification peptides and their use |
BR112022007952A2 (en) | 2019-10-28 | 2022-10-04 | Noile Immune Biotech Inc | DRUG TO TREAT CANCER, COMBINATION DRUG, DRUG COMPOSITION, IMMUNE RESPONSIVE CELL, NUCLEIC ACID DELIVERY VEHICLE AND PRODUCT |
CA3160468A1 (en) * | 2019-11-05 | 2021-05-14 | Board Of Regents, The University Of Texas System | Hla restricted hormad1 t cell receptors and uses thereof |
WO2021158818A1 (en) * | 2020-02-05 | 2021-08-12 | Synthetic Genomics, Inc. | Regulatory sequences for expression of transgenes |
CA3172447A1 (en) | 2020-03-27 | 2021-09-30 | Erik Hans MANTING | In vivo use of modified cells of leukemic origin for enhancing the efficacy of adoptive cell therapy |
CN115916963A (en) | 2020-03-27 | 2023-04-04 | 门德斯有限公司 | Ex vivo use of modified cells of leukemia origin for enhancing the efficacy of adoptive cell therapy |
CN115397866A (en) | 2020-03-31 | 2022-11-25 | 中外制药株式会社 | DLL 3-targeted multispecific antigen-binding molecules and uses thereof |
AU2021300112A1 (en) | 2020-06-29 | 2023-02-16 | Cell Medica, Inc. | Methods and compositions for the reduction of chimeric antigen receptor tonic signaling |
KR20230046313A (en) | 2020-08-06 | 2023-04-05 | 그릿스톤 바이오, 인코포레이티드 | Multi-epitope vaccine cassette |
WO2022035793A1 (en) | 2020-08-10 | 2022-02-17 | Precision Biosciences, Inc. | Antibodies and fragments specific for b-cell maturation antigen and uses thereof |
EP4222267A1 (en) | 2020-09-30 | 2023-08-09 | Vor Biopharma Inc. | Chimeric antigen receptor expression systems |
JP2023547520A (en) | 2020-11-05 | 2023-11-10 | メンドゥス・ベスローテン・フェンノートシャップ | Use of tumor-independent antigens in immunotherapy |
WO2022104090A1 (en) | 2020-11-13 | 2022-05-19 | Vor Biopharma Inc. | Methods and compositions relating to genetically engineered cells expressing chimeric antigen receptors |
WO2022189626A2 (en) | 2021-03-11 | 2022-09-15 | Mnemo Therapeutics | Tumor neoantigenic peptides |
JP2024511941A (en) * | 2021-03-11 | 2024-03-18 | テンザ、インク. | Synthetic signal peptides to direct secretion of heterologous proteins in yeast |
EP4304635A1 (en) | 2021-03-11 | 2024-01-17 | Mnemo Therapeutics | Tumor neoantigenic peptides and uses thereof |
KR20240006721A (en) | 2021-03-11 | 2024-01-15 | 엥스띠뛰 퀴리 | Membrane-transforming neoantigen peptide |
WO2022221420A2 (en) * | 2021-04-13 | 2022-10-20 | Capsida, Inc. | Selected aav compositions having preferred brain enrichment |
JP2024514933A (en) | 2021-04-23 | 2024-04-03 | ベイラー カレッジ オブ メディスン | CAR NKT expressing artificial microRNA-embedded SHRNA for down-regulation of MHC class I and II expression |
WO2022235832A1 (en) | 2021-05-06 | 2022-11-10 | Ludwig Institute For Cancer Research Ltd | Compositions and methods for immunotherapy |
WO2022238386A1 (en) | 2021-05-10 | 2022-11-17 | Institut Curie | Methods for the treatment of cancer, inflammatory diseases and autoimmune diseases |
EP4346912A1 (en) | 2021-05-25 | 2024-04-10 | Institut Curie | Myeloid cells overexpressing bcl2 |
WO2023288203A2 (en) | 2021-07-12 | 2023-01-19 | Ludwig Institute For Cancer Research Ltd | T cell receptors specific for tumor-associated antigens and methods of use thereof |
WO2023022788A1 (en) * | 2021-08-18 | 2023-02-23 | The Regents Of The University Of California | Methods and compositions for determining risk of autism spectrum disorders |
WO2023064872A1 (en) | 2021-10-14 | 2023-04-20 | Precision Biosciences, Inc. | Combinations of anti-bcma car t cells and gamma secretase inhibitors |
WO2023192626A1 (en) * | 2022-04-01 | 2023-10-05 | The Regents Of The University Of California | Methods and compositions for treating gliomas |
US20240002800A1 (en) | 2022-05-16 | 2024-01-04 | Mendus B.V. | Use of leukemia-derived cells for enhancing natural killer (nk) cell therapy |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
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US6287801B1 (en) * | 1996-07-22 | 2001-09-11 | Smithkline Beecham Corporation | Nucleic acids encoding the G-protein coupled receptor HNFDS78 |
US6555339B1 (en) * | 1997-04-14 | 2003-04-29 | Arena Pharmaceuticals, Inc. | Non-endogenous, constitutively activated human protein-coupled receptors |
US20030235883A1 (en) * | 2000-03-31 | 2003-12-25 | Tang Y. Tom | Novel nucleic acids and polypeptides |
US6436703B1 (en) * | 2000-03-31 | 2002-08-20 | Hyseq, Inc. | Nucleic acids and polypeptides |
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