WO2001079818A3 - Infrared atr glucose measurement system - Google Patents

Infrared atr glucose measurement system Download PDF

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Publication number
WO2001079818A3
WO2001079818A3 PCT/US2001/011860 US0111860W WO0179818A3 WO 2001079818 A3 WO2001079818 A3 WO 2001079818A3 US 0111860 W US0111860 W US 0111860W WO 0179818 A3 WO0179818 A3 WO 0179818A3
Authority
WO
WIPO (PCT)
Prior art keywords
glucose measurement
human body
measurement system
blood glucose
glucose level
Prior art date
Application number
PCT/US2001/011860
Other languages
French (fr)
Other versions
WO2001079818A2 (en
Inventor
Herbert L Berman
Jeffrey N Roe
Original Assignee
Medoptix Inc
Herbert L Berman
Jeffrey N Roe
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medoptix Inc, Herbert L Berman, Jeffrey N Roe filed Critical Medoptix Inc
Priority to AU2001255319A priority Critical patent/AU2001255319A1/en
Publication of WO2001079818A2 publication Critical patent/WO2001079818A2/en
Publication of WO2001079818A3 publication Critical patent/WO2001079818A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55Specular reflectivity
    • G01N21/552Attenuated total reflection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/24Hygienic packaging for medical sensors; Maintaining apparatus for sensor hygiene
    • A61B2562/245Means for cleaning the sensor in-situ or during use, e.g. hygienic wipes

Abstract

This involves a non-invasive glucose measurement device and a process for determining blood glucose level in the human body using the device. In typical operation, the glucose measurement device is self-normalizing in that it does not employ an independent reference sample in its operation. The device uses attenuated total reflection (ATR) infrared spectroscopy. Preferably, the device is used on a fingertip and compares two specific regions of a measured infrared spectrum to determine the blood glucose level of the user. Clearly, this device is especially suitable for monitoring glucose levels in the human body, and is especially beneficial to users having diabetes mellitus. The device and procedure may be used for other analyte materials which exhibit unique mid-IR signatures of the type described herein and that are found in appropriate regions of the outer skin.
PCT/US2001/011860 2000-04-12 2001-04-11 Infrared atr glucose measurement system WO2001079818A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001255319A AU2001255319A1 (en) 2000-04-12 2001-04-11 Infrared atr glucose measurement system

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/547,433 2000-04-12
US09/547,433 US6424851B1 (en) 1998-10-13 2000-04-12 Infrared ATR glucose measurement system (II)

Publications (2)

Publication Number Publication Date
WO2001079818A2 WO2001079818A2 (en) 2001-10-25
WO2001079818A3 true WO2001079818A3 (en) 2002-07-18

Family

ID=24184624

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/011860 WO2001079818A2 (en) 2000-04-12 2001-04-11 Infrared atr glucose measurement system

Country Status (4)

Country Link
US (8) US6424851B1 (en)
AU (1) AU2001255319A1 (en)
TW (1) TW550380B (en)
WO (1) WO2001079818A2 (en)

Families Citing this family (90)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030176775A1 (en) * 1998-10-13 2003-09-18 Medoptix, Inc. Cleaning kit for an infrared glucose measurement system
US20050107676A1 (en) * 2003-03-07 2005-05-19 Acosta George M. Method and apparatus for noninvasive glucose concentration estimation through near-infrared spectroscopy
US7317938B2 (en) * 1999-10-08 2008-01-08 Sensys Medical, Inc. Method of adapting in-vitro models to aid in noninvasive glucose determination
DE19952215C2 (en) * 1999-10-29 2001-10-31 Roche Diagnostics Gmbh Test element analysis system
US6522903B1 (en) * 2000-10-19 2003-02-18 Medoptix, Inc. Glucose measurement utilizing non-invasive assessment methods
US8174394B2 (en) * 2001-04-11 2012-05-08 Trutouch Technologies, Inc. System for noninvasive determination of analytes in tissue
US8581697B2 (en) * 2001-04-11 2013-11-12 Trutouch Technologies Inc. Apparatuses for noninvasive determination of in vivo alcohol concentration using raman spectroscopy
US7756558B2 (en) * 2004-05-24 2010-07-13 Trutouch Technologies, Inc. Apparatus and methods for mitigating the effects of foreign interferents on analyte measurements in spectroscopy
US6748250B1 (en) * 2001-04-27 2004-06-08 Medoptix, Inc. Method and system of monitoring a patient
US20090137888A9 (en) * 2001-04-27 2009-05-28 Berman Herbert L System for monitoring of patients
US7262836B2 (en) * 2002-02-21 2007-08-28 Matsushita Electrical Industrial Co., Ltd. Apparatus for measuring biological information and method for measuring biological information
JP2003270131A (en) * 2002-03-19 2003-09-25 Matsushita Electric Ind Co Ltd Concentration measurement method for specific component
US20040027659A1 (en) * 2002-08-08 2004-02-12 Messerschmidt Robert G. Sample holder
CN100483106C (en) * 2002-09-29 2009-04-29 天津市先石光学技术有限公司 Optical method for detecting discerptible medium skin layer and deep layer information
US7233817B2 (en) * 2002-11-01 2007-06-19 Brian Yen Apparatus and method for pattern delivery of radiation and biological characteristic analysis
EP1464273B1 (en) * 2003-04-03 2006-11-29 Matsushita Electric Industrial Co., Ltd. Method and device for measuring concentration of specific component
US6968222B2 (en) * 2003-05-02 2005-11-22 Oculir, Inc. Methods and device for non-invasive analyte measurement
US6958039B2 (en) * 2003-05-02 2005-10-25 Oculir, Inc. Method and instruments for non-invasive analyte measurement
US6975892B2 (en) * 2003-10-21 2005-12-13 Oculir, Inc. Methods for non-invasive analyte measurement from the conjunctiva
WO2004099824A2 (en) * 2003-05-02 2004-11-18 Oculir, Inc. Methods and device for non-invasive analyte measurement
US20040225206A1 (en) * 2003-05-09 2004-11-11 Kouchnir Mikhail A. Non-invasive analyte measurement device having increased signal to noise ratios
US20040242977A1 (en) * 2003-06-02 2004-12-02 Dosmann Andrew J. Non-invasive methods of detecting analyte concentrations using hyperosmotic fluids
US20050007596A1 (en) * 2003-07-11 2005-01-13 Wilks Enterprise, Inc. Apparatus and method for increasing the sensitivity of in-line infrared sensors
US20060224057A1 (en) * 2003-10-21 2006-10-05 Oculir, Inc. Methods for non-invasive analyte measurement
US20050090725A1 (en) * 2003-10-28 2005-04-28 Joseph Page Disposable couplings for biometric instruments
US20050267346A1 (en) * 2004-01-30 2005-12-01 3Wave Optics, Llc Non-invasive blood component measurement system
US20050171413A1 (en) * 2004-02-04 2005-08-04 Medoptix, Inc. Integrated device for non-invasive analyte measurement
US7333186B2 (en) * 2004-03-17 2008-02-19 Matsushita Electric Industrial Co., Ltd. Method and device for measuring biological information
US20060258919A1 (en) * 2004-04-14 2006-11-16 Oculir, Inc. Non-Invasive Analyte Measurement Device for Measuring Tears and Other Ocular Elements Using Electromagnetic Radiation and Method of Using the Same
US20080009688A1 (en) * 2004-04-14 2008-01-10 Oculir, Inc. Methods for non-invasive analyte measurement
US8515506B2 (en) * 2004-05-24 2013-08-20 Trutouch Technologies, Inc. Methods for noninvasive determination of in vivo alcohol concentration using Raman spectroscopy
US8730047B2 (en) 2004-05-24 2014-05-20 Trutouch Technologies, Inc. System for noninvasive determination of analytes in tissue
US20110178420A1 (en) * 2010-01-18 2011-07-21 Trent Ridder Methods and apparatuses for improving breath alcohol testing
US20080319286A1 (en) * 2004-05-24 2008-12-25 Trent Ridder Optical Probes for Non-Invasive Analyte Measurements
US20060015023A1 (en) * 2004-06-10 2006-01-19 Monfre Stephen L Preparation kit for noninvasive glucose concentration determination
WO2006011487A1 (en) * 2004-07-30 2006-02-02 National University Corporation Chiba University Method for measuring glucose concentration in blood using infrared spectroscopy and instrument employing it
ITMI20041644A1 (en) * 2004-08-11 2004-11-11 Eni Spa PROCEDURE FOR THE STORAGE OF SULFUR WITH ZERO EMISSION
US7236814B2 (en) * 2004-08-20 2007-06-26 Matsushita Electric Industrial Co., Ltd. Optical member for biological information measurement, biological information calculation apparatus, biological information calculation method, computer-executable program, and recording medium
US20060087760A1 (en) * 2004-10-21 2006-04-27 International Business Machines Corporation Simple method of protecting customer data on hard drives returned from the field
GB0501826D0 (en) * 2005-01-28 2005-03-09 Melys Diagnostics Ltd Apparatus for measurement of analyte concentration
US20090270698A1 (en) * 2005-10-21 2009-10-29 Masahiko Shioi Bioinformation measurement device
WO2007049562A1 (en) * 2005-10-24 2007-05-03 Matsushita Electric Industrial Co., Ltd. Apparatus for measuring biological component concentration
EP1820441A1 (en) * 2006-02-16 2007-08-22 Roche Diagnostics GmbH Microneedle arrays with attenuated total reflection (ATR) sensor
EP1905356A4 (en) * 2006-03-10 2008-10-15 Matsushita Electric Ind Co Ltd Living body ingredient concentration measuring instrument
WO2008070352A2 (en) * 2006-10-27 2008-06-12 Complete Genomics, Inc. Efficient arrays of amplified polynucleotides
US20080269616A1 (en) * 2006-11-17 2008-10-30 Bloom Matthew M Mir spectroscopy of tissue
US7675611B2 (en) 2007-05-21 2010-03-09 Ahura Scientific Inc. Handheld infrared and Raman measurement devices and methods
US8203700B2 (en) * 2007-05-21 2012-06-19 Ahura Scientific Inc. Supporting remote analysis
BRPI0816925B8 (en) 2007-09-13 2021-06-22 Univ Missouri lighting light funnel, light gathering funnel and apparatus
CA2700996C (en) * 2007-10-04 2016-12-13 The Curators Of The University Of Missouri Optical device components
US7961305B2 (en) * 2007-10-23 2011-06-14 The Curators Of The University Of Missouri Optical device components
CN101990633A (en) * 2008-02-01 2011-03-23 莱尔照明公司 Methods, devices and kits for peri-critical reflectance spectroscopy
BRPI0909825B8 (en) 2008-03-25 2021-06-22 Univ Missouri method and systems for non-invasive blood glucose detection using spectral data from one or more non-glucose components
CN102083360B (en) 2008-05-22 2015-04-15 密苏里大学董事会 Method and system for non-invasive optical blood glucose detection utilizing spectral data analysis
EP2413784A4 (en) * 2009-04-01 2014-01-22 Univ Missouri Optical spectroscopy device for non-invasive blood glucose detection and associated method of use
JP2012523567A (en) 2009-04-07 2012-10-04 レア ライト インコーポレイテッド Near-critical reflectance spectroscopy measurement device, system, and method
US8235897B2 (en) 2010-04-27 2012-08-07 A.D. Integrity Applications Ltd. Device for non-invasively measuring glucose
WO2012109116A2 (en) * 2011-02-07 2012-08-16 Quantum Catch, Llc Noninvasive eye-property monitoring, including aqueous-humor glucose monitoring as an indication of blood glucose level
US8970838B2 (en) 2011-04-29 2015-03-03 Avolonte Health LLC Method and apparatus for evaluating a sample through variable angle Raman spectroscopy
WO2014051685A1 (en) * 2012-09-27 2014-04-03 Ivwatch, Llc Apparatus and method for mitigating noise affecting a transcutaneous signal
US9693694B2 (en) 2012-11-21 2017-07-04 Folim G. Halaka Cancer cell detection using dielectrophoretic dynamic light scattering (DDLS) spectroscopy
US8843186B2 (en) 2012-11-21 2014-09-23 Folim G. Halaka Non-invasive reagentless glucose determination
DE102014108424B3 (en) 2014-06-16 2015-06-11 Johann Wolfgang Goethe-Universität Non-invasive substance analysis
KR102261856B1 (en) * 2014-08-12 2021-06-07 삼성전자주식회사 Non-invasive measuring device for bio-analyte and non-invasive measuring method for bio-analyte
KR102290281B1 (en) 2014-08-27 2021-08-17 삼성전자주식회사 Method and apparatus for processing biosignal
KR102277902B1 (en) 2014-09-05 2021-07-15 삼성전자주식회사 Object contact pressure meter and methods of manufacturing and measuring the same
KR102323207B1 (en) 2014-09-29 2021-11-08 삼성전자주식회사 Device for correcting light absorption spectrum and methods of manufacturing the same and correcting light absorption spectrum
US9459201B2 (en) 2014-09-29 2016-10-04 Zyomed Corp. Systems and methods for noninvasive blood glucose and other analyte detection and measurement using collision computing
KR102390874B1 (en) 2014-10-29 2022-04-26 삼성전자주식회사 Glucose measure apparatus and method of measuring glucose thereof
WO2017097276A1 (en) 2015-12-09 2017-06-15 Diamontech Gmbh Apparatus and method for analyzing a material
CN108369183B (en) * 2015-12-09 2022-08-19 迪亚蒙泰克股份有限公司 Device and method for analyzing materials
US9554738B1 (en) 2016-03-30 2017-01-31 Zyomed Corp. Spectroscopic tomography systems and methods for noninvasive detection and measurement of analytes using collision computing
RU2640777C2 (en) 2016-04-28 2018-01-11 Самсунг Электроникс Ко., Лтд. Autonomous wearable optical device and method for continuous noninvasive measurement of physiological parameters
WO2018122319A1 (en) * 2016-12-30 2018-07-05 Swiss Spectral Ag Device and method for the non-invasive determination of analytes
CN110177503B (en) * 2017-01-23 2022-12-06 豪夫迈·罗氏有限公司 Implantable sensor element and method for detecting at least one analyte in a body fluid
US10506926B2 (en) 2017-02-18 2019-12-17 Arc Devices Limited Multi-vital sign detector in an electronic medical records system
US10492684B2 (en) 2017-02-21 2019-12-03 Arc Devices Limited Multi-vital-sign smartphone system in an electronic medical records system
US10602987B2 (en) 2017-08-10 2020-03-31 Arc Devices Limited Multi-vital-sign smartphone system in an electronic medical records system
WO2019039269A1 (en) * 2017-08-23 2019-02-28 Ricoh Company, Ltd. Measuring apparatus and measuring method
JP2019037752A (en) * 2017-08-23 2019-03-14 株式会社リコー Measuring apparatus and measuring method
CA3079209A1 (en) 2017-10-16 2019-04-25 Massachusetts Institute Of Technology Systems, devices and methods for non-invasive hematological measurements
WO2019138382A1 (en) * 2018-01-14 2019-07-18 Gopalakrishnan Muralidharan Non-invasive blood sugar level monitoring apparatus integrated with real-time health support system
US10485431B1 (en) 2018-05-21 2019-11-26 ARC Devices Ltd. Glucose multi-vital-sign system in an electronic medical records system
WO2020002342A1 (en) * 2018-06-29 2020-01-02 F. Hoffmann-La Roche Ag Fully implantable sensor element and method for detecting at least one analyte in a body fluid
ES2774983B2 (en) 2019-01-22 2021-06-10 Univ Sevilla PORTABLE DEVICE AND METHOD FOR NON-INVASIVE ESTIMATION OF GLUCOSE LEVEL IN BLOOD
WO2020158348A1 (en) * 2019-01-31 2020-08-06 国立大学法人東北大学 Device and method for measuring blood sugar level
EP3977097A1 (en) 2019-05-29 2022-04-06 Viktor Tomasov Compact device for non-invasive measurement of markers in physiological fluids
CN116211296A (en) 2019-07-24 2023-06-06 麻省理工学院 Finger insert for plication imaging device
WO2021242983A1 (en) 2020-05-28 2021-12-02 Leuko Labs, Inc. A method to detect white blood cells and/or white blood cell subtypes form non-invasive capillary videos
WO2021247300A1 (en) 2020-06-01 2021-12-09 Arc Devices Limited Apparatus and methods for measuring blood pressure and other vital signs via a finger

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4071020A (en) * 1976-06-03 1978-01-31 Xienta, Inc. Apparatus and methods for performing in-vivo measurements of enzyme activity
US4169676A (en) * 1976-02-20 1979-10-02 Nils Kaiser Method for determining the contents of metabolic products in the blood
EP0355368A2 (en) * 1988-07-12 1990-02-28 Orion-Yhtymà„ Oy A cleansing-agent composition and its use
EP0404562A2 (en) * 1989-06-21 1990-12-27 University Of New Mexico Method of and apparatus for determining the similarity of a biological analyte from a model constructed from known biological fluids
US5470323A (en) * 1992-12-07 1995-11-28 Creative Products Resource Associates, Ltd. Packaging system with in-tandem applicator pads for topical drug delivery
US5786892A (en) * 1994-04-07 1998-07-28 Ford Global Technologies, Inc. Plastics identification
US5935062A (en) * 1995-08-09 1999-08-10 Rio Grande Medical Technologies, Inc. Diffuse reflectance monitoring apparatus
US5962441A (en) * 1991-11-25 1999-10-05 Richardson-Vicks Inc. Use of salicylic acid for regulating skin wrinkles and/or skin atrophy
WO2000021437A2 (en) * 1998-10-13 2000-04-20 Medoptix, Inc. Infrared atr glucose measurement system
WO2000057177A1 (en) * 1999-03-11 2000-09-28 Technical Chemicals & Products, Inc. Noninvasive transdermal systems and methods for detecting an analyte in a biological fluid

Family Cites Families (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4151001A (en) 1977-10-11 1979-04-24 Akzona Incorporated Beeswax substitutes
DE2934190A1 (en) 1979-08-23 1981-03-19 Müller, Gerhard, Prof. Dr.-Ing., 7080 Aalen METHOD AND DEVICE FOR MOLECULAR SPECTROSCOPY, ESPECIALLY FOR DETERMINING METABOLISM PRODUCTS
PT77919B (en) 1983-01-07 1986-04-16 Tate & Lyle Plc Process for the production of solid fructose
IL68115A (en) 1983-03-14 1987-03-31 Rosenberg Lior Fluid flow detector particularly useful for microvascular monitoring
DE3501708A1 (en) 1985-01-19 1986-07-24 Wabco Westinghouse Fahrzeugbremsen GmbH, 3000 Hannover ELECTROMAGNETICALLY OPERABLE MULTI-WAY VALVE
ES2080068T3 (en) 1988-02-13 1996-02-01 Suntory Ltd DERIVATIVES OF 2-PYRANONE AND ITS PREPARATION PROCEDURE.
US5028787A (en) 1989-01-19 1991-07-02 Futrex, Inc. Non-invasive measurement of blood glucose
US5086229A (en) 1989-01-19 1992-02-04 Futrex, Inc. Non-invasive measurement of blood glucose
US5068536A (en) * 1989-01-19 1991-11-26 Futrex, Inc. Method for providing custom calibration for near infrared instruments for measurement of blood glucose
US5178142A (en) 1989-05-23 1993-01-12 Vivascan Corporation Electromagnetic method and apparatus to measure constituents of human or animal tissue
CA2028261C (en) 1989-10-28 1995-01-17 Won Suck Yang Non-invasive method and apparatus for measuring blood glucose concentration
US5222496A (en) * 1990-02-02 1993-06-29 Angiomedics Ii, Inc. Infrared glucose sensor
US5115133A (en) 1990-04-19 1992-05-19 Inomet, Inc. Testing of body fluid constituents through measuring light reflected from tympanic membrane
JP3329453B2 (en) 1990-08-29 2002-09-30 カデル、セオドアー・イー Finger receiving device
DE4030836A1 (en) 1990-09-28 1992-04-02 Kim Yoon Ok DEVICE FOR QUALITATIVELY AND / OR QUANTITATIVELY DETERMINING THE COMPOSITION OF A SAMPLE TO BE ANALYZED
US5113860A (en) 1991-03-15 1992-05-19 Minnesota Mining And Manufacturing Company Non-invasive transmucosal drug level monitoring method
US5817605A (en) 1991-06-03 1998-10-06 Ethyl Petroleum Additives, Inc. Automatic transmission and wet brake fluids and additive package therefor
US5749217A (en) 1991-12-26 1998-05-12 Caterpillar Inc. Low emission combustion system for a gas turbine engine
JP3144030B2 (en) 1992-02-24 2001-03-07 東陶機器株式会社 Health management network system
US5452716A (en) * 1992-02-25 1995-09-26 Novo Nordisk A/S Method and device for in vivo measuring the concentration of a substance in the blood
US5370114A (en) * 1992-03-12 1994-12-06 Wong; Jacob Y. Non-invasive blood chemistry measurement by stimulated infrared relaxation emission
US5765717A (en) 1992-06-03 1998-06-16 Gottselig; John C. Wet hygienic towel dispenser
US5390238A (en) 1992-06-15 1995-02-14 Motorola, Inc. Health support system
US5433197A (en) 1992-09-04 1995-07-18 Stark; Edward W. Non-invasive glucose measurement method and apparatus
US6172743B1 (en) 1992-10-07 2001-01-09 Chemtrix, Inc. Technique for measuring a blood analyte by non-invasive spectrometry in living tissue
US5398681A (en) 1992-12-10 1995-03-21 Sunshine Medical Instruments, Inc. Pocket-type instrument for non-invasive measurement of blood glucose concentration
US5313941A (en) 1993-01-28 1994-05-24 Braig James R Noninvasive pulsed infrared spectrophotometer
TW242206B (en) 1993-08-27 1995-03-01 At & T Corp
US5582184A (en) 1993-10-13 1996-12-10 Integ Incorporated Interstitial fluid collection and constituent measurement
US5458140A (en) 1993-11-15 1995-10-17 Non-Invasive Monitoring Company (Nimco) Enhancement of transdermal monitoring applications with ultrasound and chemical enhancers
JPH07184883A (en) 1993-12-27 1995-07-25 Satoshi Yoshida Apparatus for measuring surface of living body
ES2177680T3 (en) 1994-12-20 2002-12-16 Oreal REVITALIZING MAKEUP COMPOSITION.
HU216847B (en) * 1995-05-23 1999-12-28 Gyula Domján Method and arrangement for prompt non-invasive determination of blood parameters
US5655530A (en) 1995-08-09 1997-08-12 Rio Grande Medical Technologies, Inc. Method for non-invasive blood analyte measurement with improved optical interface
US6152876A (en) 1997-04-18 2000-11-28 Rio Grande Medical Technologies, Inc. Method for non-invasive blood analyte measurement with improved optical interface
US5879367A (en) 1995-09-08 1999-03-09 Integ, Inc. Enhanced interstitial fluid collection
AU7015096A (en) 1995-09-08 1997-04-09 Integ, Inc. Body fluid sampler
US5682233A (en) 1995-09-08 1997-10-28 Integ, Inc. Interstitial fluid sampler
AUPN800796A0 (en) 1996-02-09 1996-03-07 Unisearch Limited Visual inspection system for leather hide
US6001067A (en) 1997-03-04 1999-12-14 Shults; Mark C. Device and method for determining analyte levels
US5900632A (en) 1997-03-12 1999-05-04 Optiscan Biomedical Corporation Subsurface thermal gradient spectrometry
JP3770707B2 (en) * 1997-08-26 2006-04-26 松下電器産業株式会社 Attenuated total reflection measuring apparatus and method for measuring specific components using the same
GB2329015B (en) 1997-09-05 2002-02-13 Samsung Electronics Co Ltd Method and device for noninvasive measurement of concentrations of blood components
JPH11155844A (en) * 1997-11-27 1999-06-15 Horiba Ltd Living body measuring device with constant living body contact area
JP3543923B2 (en) 1997-12-25 2004-07-21 富士写真フイルム株式会社 Glucose concentration measurement device
US6205272B1 (en) 1998-02-27 2001-03-20 Equitech Int'l Corp. Fiber optic probe for attenuated total internal reflection spectrophotometry
JP3763687B2 (en) 1998-12-25 2006-04-05 三井金属鉱業株式会社 Blood glucose level measuring device

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4169676A (en) * 1976-02-20 1979-10-02 Nils Kaiser Method for determining the contents of metabolic products in the blood
US4071020A (en) * 1976-06-03 1978-01-31 Xienta, Inc. Apparatus and methods for performing in-vivo measurements of enzyme activity
EP0355368A2 (en) * 1988-07-12 1990-02-28 Orion-Yhtymà„ Oy A cleansing-agent composition and its use
EP0404562A2 (en) * 1989-06-21 1990-12-27 University Of New Mexico Method of and apparatus for determining the similarity of a biological analyte from a model constructed from known biological fluids
US5962441A (en) * 1991-11-25 1999-10-05 Richardson-Vicks Inc. Use of salicylic acid for regulating skin wrinkles and/or skin atrophy
US5470323A (en) * 1992-12-07 1995-11-28 Creative Products Resource Associates, Ltd. Packaging system with in-tandem applicator pads for topical drug delivery
US5786892A (en) * 1994-04-07 1998-07-28 Ford Global Technologies, Inc. Plastics identification
US5935062A (en) * 1995-08-09 1999-08-10 Rio Grande Medical Technologies, Inc. Diffuse reflectance monitoring apparatus
WO2000021437A2 (en) * 1998-10-13 2000-04-20 Medoptix, Inc. Infrared atr glucose measurement system
WO2000057177A1 (en) * 1999-03-11 2000-09-28 Technical Chemicals & Products, Inc. Noninvasive transdermal systems and methods for detecting an analyte in a biological fluid

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Publication number Publication date
US6424849B1 (en) 2002-07-23
US6362144B1 (en) 2002-03-26
AU2001255319A1 (en) 2001-10-30
US6445938B1 (en) 2002-09-03
US6430424B1 (en) 2002-08-06
US20020151773A1 (en) 2002-10-17
WO2001079818A2 (en) 2001-10-25
US6424848B1 (en) 2002-07-23
US6424851B1 (en) 2002-07-23
TW550380B (en) 2003-09-01
US6421548B1 (en) 2002-07-16

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