WO2001084124A3 - Methods and systems using field-based light scattering spectroscopy - Google Patents

Methods and systems using field-based light scattering spectroscopy Download PDF

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Publication number
WO2001084124A3
WO2001084124A3 PCT/US2001/040612 US0140612W WO0184124A3 WO 2001084124 A3 WO2001084124 A3 WO 2001084124A3 US 0140612 W US0140612 W US 0140612W WO 0184124 A3 WO0184124 A3 WO 0184124A3
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WO
WIPO (PCT)
Prior art keywords
systems
methods
field
light scattering
based light
Prior art date
Application number
PCT/US2001/040612
Other languages
French (fr)
Other versions
WO2001084124A2 (en
Inventor
Changhuei Yang
Adam P Wax
Lev T Perelman
Ramachandra R Dasari
Michael S Feld
Original Assignee
Massachusetts Inst Technology
Changhuei Yang
Adam P Wax
Lev T Perelman
Ramachandra R Dasari
Michael S Feld
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Inst Technology, Changhuei Yang, Adam P Wax, Lev T Perelman, Ramachandra R Dasari, Michael S Feld filed Critical Massachusetts Inst Technology
Priority to AU59807/01A priority Critical patent/AU5980701A/en
Priority to CA002377724A priority patent/CA2377724A1/en
Priority to EP01933374A priority patent/EP1277040A2/en
Priority to KR1020017016801A priority patent/KR20020027377A/en
Priority to JP2001581098A priority patent/JP5134177B2/en
Publication of WO2001084124A2 publication Critical patent/WO2001084124A2/en
Publication of WO2001084124A3 publication Critical patent/WO2001084124A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/4795—Scattering, i.e. diffuse reflection spatially resolved investigating of object in scattering medium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062—Arrangements for scanning
    • A61B5/0066—Optical coherence imaging
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/41—Refractivity; Phase-affecting properties, e.g. optical path length
    • G01N21/45—Refractivity; Phase-affecting properties, e.g. optical path length using interferometric methods; using Schlieren methods

Abstract

The present invention relates to systems and methods of field-based light scattering spectroscopy. These systems and methods provide for the diagnosis of tissue (26) by measuring the size and distribution of cellular characteristics. Field based measurements provide phase information resulting from the interaction of scatterers within the material and the incident wavefront. These measurements can be used to provide three dimensional images of tissue.
PCT/US2001/040612 2000-04-28 2001-04-27 Methods and systems using field-based light scattering spectroscopy WO2001084124A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
AU59807/01A AU5980701A (en) 2000-04-28 2001-04-27 Methods and systems using field-based light scattering spectroscopy
CA002377724A CA2377724A1 (en) 2000-04-28 2001-04-27 Methods and systems using field-based light scattering spectroscopy
EP01933374A EP1277040A2 (en) 2000-04-28 2001-04-27 Methods and systems using field-based light scattering spectroscopy
KR1020017016801A KR20020027377A (en) 2000-04-28 2001-04-27 Methods and systems using field-based light scattering spectroscopy
JP2001581098A JP5134177B2 (en) 2000-04-28 2001-04-27 Systems using light-scattering spectroscopy based on electric fields

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20018700P 2000-04-28 2000-04-28
US60/200,187 2000-04-28

Publications (2)

Publication Number Publication Date
WO2001084124A2 WO2001084124A2 (en) 2001-11-08
WO2001084124A3 true WO2001084124A3 (en) 2002-06-20

Family

ID=22740679

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/040612 WO2001084124A2 (en) 2000-04-28 2001-04-27 Methods and systems using field-based light scattering spectroscopy

Country Status (8)

Country Link
US (1) US6847456B2 (en)
EP (1) EP1277040A2 (en)
JP (1) JP5134177B2 (en)
KR (1) KR20020027377A (en)
CN (1) CN1279345C (en)
AU (1) AU5980701A (en)
CA (1) CA2377724A1 (en)
WO (1) WO2001084124A2 (en)

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EP2444783B1 (en) * 2005-10-11 2015-03-04 Duke University Systems and method for fiber-based endoscopic angle-resolved low coherence interferometry
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US20080021276A1 (en) * 2006-07-21 2008-01-24 Oncoscope, Inc. Protective probe tip, particularly for use on a fiber-optic probe used in an endoscopic application
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Also Published As

Publication number Publication date
CA2377724A1 (en) 2001-11-08
US20020101593A1 (en) 2002-08-01
JP5134177B2 (en) 2013-01-30
AU5980701A (en) 2001-11-12
KR20020027377A (en) 2002-04-13
EP1277040A2 (en) 2003-01-22
CN1279345C (en) 2006-10-11
WO2001084124A2 (en) 2001-11-08
CN1451094A (en) 2003-10-22
US6847456B2 (en) 2005-01-25
JP2003532112A (en) 2003-10-28

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