WO2001085102A3 - Formulation d'emulsion a phase continue aqueuse contenant de l'hydroquinone et du retinol - Google Patents

Formulation d'emulsion a phase continue aqueuse contenant de l'hydroquinone et du retinol Download PDF

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Publication number
WO2001085102A3
WO2001085102A3 PCT/US2001/014434 US0114434W WO0185102A3 WO 2001085102 A3 WO2001085102 A3 WO 2001085102A3 US 0114434 W US0114434 W US 0114434W WO 0185102 A3 WO0185102 A3 WO 0185102A3
Authority
WO
WIPO (PCT)
Prior art keywords
retinol
oil
water emulsion
formulation containing
containing hydroquinone
Prior art date
Application number
PCT/US2001/014434
Other languages
English (en)
Other versions
WO2001085102A8 (fr
WO2001085102A2 (fr
Inventor
Sandhya B Singh
Marie-Helene Beausoleil
Subhash J Saxena
Original Assignee
Scherer Technologies Inc R P
Sandhya B Singh
Marie-Helene Beausoleil
Subhash J Saxena
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scherer Technologies Inc R P, Sandhya B Singh, Marie-Helene Beausoleil, Subhash J Saxena filed Critical Scherer Technologies Inc R P
Priority to AU2001257534A priority Critical patent/AU2001257534A1/en
Priority to CA2408137A priority patent/CA2408137C/fr
Priority to EP01931059A priority patent/EP1278504A2/fr
Publication of WO2001085102A2 publication Critical patent/WO2001085102A2/fr
Publication of WO2001085102A3 publication Critical patent/WO2001085102A3/fr
Publication of WO2001085102A8 publication Critical patent/WO2001085102A8/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A61K8/062—Oil-in-water emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241—Containing particulates characterized by their shape and/or structure
    • A61K8/0275—Containing agglomerated particulates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241—Containing particulates characterized by their shape and/or structure
    • A61K8/0279—Porous; Hollow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/347—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8105—Compositions of homopolymers or copolymers of unsaturated aliphatic hydrocarbons having only one carbon-to-carbon double bond; Compositions of derivatives of such polymers
    • A61K8/8117—Homopolymers or copolymers of aromatic olefines, e.g. polystyrene; Compositions of derivatives of such polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8152—Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/56—Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms

Abstract

L'invention concerne une formulation d'émulsion à phase continue aqueuse contenant de l'hydroquinone et du rétinol. Une émulsion à phase continue aqueuse contient de l'hydroquinone enfermée dans des micro-agrégats absorbants ou imprégnée dans des microparticules poreuses et des microparticules imprégnées de rétinol.
PCT/US2001/014434 2000-05-05 2001-05-03 Formulation d'emulsion a phase continue aqueuse contenant de l'hydroquinone et du retinol WO2001085102A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2001257534A AU2001257534A1 (en) 2000-05-05 2001-05-03 Oil-in-water emulsion formulation containing hydroquinone and retinol
CA2408137A CA2408137C (fr) 2000-05-05 2001-05-03 Formulation d'emulsion a phase continue aqueuse contenant de l'hydroquinone et du retinol
EP01931059A EP1278504A2 (fr) 2000-05-05 2001-05-03 Formulation d'emulsion a phase continue aqueuse contenant de l'hydroquinone et du retinol

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56532000A 2000-05-05 2000-05-05
US09/565,320 2000-05-05

Publications (3)

Publication Number Publication Date
WO2001085102A2 WO2001085102A2 (fr) 2001-11-15
WO2001085102A3 true WO2001085102A3 (fr) 2002-08-29
WO2001085102A8 WO2001085102A8 (fr) 2003-11-20

Family

ID=24258089

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/014434 WO2001085102A2 (fr) 2000-05-05 2001-05-03 Formulation d'emulsion a phase continue aqueuse contenant de l'hydroquinone et du retinol

Country Status (5)

Country Link
EP (1) EP1278504A2 (fr)
AR (1) AR028085A1 (fr)
AU (1) AU2001257534A1 (fr)
CA (1) CA2408137C (fr)
WO (1) WO2001085102A2 (fr)

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US6673847B2 (en) * 2002-04-01 2004-01-06 Rohm And Haas Company Water immiscible porogen removal process
IL152486A0 (en) 2002-10-25 2003-05-29 Meir Eini Alcohol-free cosmetic and pharmaceutical foam carrier
US9668972B2 (en) 2002-10-25 2017-06-06 Foamix Pharmaceuticals Ltd. Nonsteroidal immunomodulating kit and composition and uses thereof
AU2003279493B2 (en) 2002-10-25 2009-08-20 Foamix Pharmaceuticals Ltd. Cosmetic and pharmaceutical foam
US9211259B2 (en) 2002-11-29 2015-12-15 Foamix Pharmaceuticals Ltd. Antibiotic kit and composition and uses thereof
US7704518B2 (en) 2003-08-04 2010-04-27 Foamix, Ltd. Foamable vehicle and pharmaceutical compositions thereof
US7700076B2 (en) 2002-10-25 2010-04-20 Foamix, Ltd. Penetrating pharmaceutical foam
US9265725B2 (en) 2002-10-25 2016-02-23 Foamix Pharmaceuticals Ltd. Dicarboxylic acid foamable vehicle and pharmaceutical compositions thereof
US8900554B2 (en) 2002-10-25 2014-12-02 Foamix Pharmaceuticals Ltd. Foamable composition and uses thereof
US10117812B2 (en) 2002-10-25 2018-11-06 Foamix Pharmaceuticals Ltd. Foamable composition combining a polar solvent and a hydrophobic carrier
US7820145B2 (en) 2003-08-04 2010-10-26 Foamix Ltd. Oleaginous pharmaceutical and cosmetic foam
US20080138296A1 (en) 2002-10-25 2008-06-12 Foamix Ltd. Foam prepared from nanoemulsions and uses
US8795693B2 (en) 2003-08-04 2014-08-05 Foamix Ltd. Compositions with modulating agents
US10252088B2 (en) 2004-12-02 2019-04-09 Obagi Cosmeceuticals Llc Topical compositions and methods of manufacturing them in specifically treated steel vessels
US20140161751A1 (en) * 2004-12-02 2014-06-12 Omp, Inc. Stable skin care compositions and methods for manufacturing them
US8999356B1 (en) 2004-12-03 2015-04-07 Omp, Inc. Drug delivery system
US7976854B2 (en) 2005-12-30 2011-07-12 Omp, Inc. Method of treating skin requiring skin cancer treatment
US20080260655A1 (en) 2006-11-14 2008-10-23 Dov Tamarkin Substantially non-aqueous foamable petrolatum based pharmaceutical and cosmetic compositions and their uses
US8636982B2 (en) 2007-08-07 2014-01-28 Foamix Ltd. Wax foamable vehicle and pharmaceutical compositions thereof
WO2009069006A2 (fr) 2007-11-30 2009-06-04 Foamix Ltd. Peroxyde de benzoyle contenant de la mousse
WO2009090495A2 (fr) 2007-12-07 2009-07-23 Foamix Ltd. Vecteurs moussants siliconés à base d'huile et de liquide, et formulations
US8273791B2 (en) 2008-01-04 2012-09-25 Jr Chem, Llc Compositions, kits and regimens for the treatment of skin, especially décolletage
JP2011510999A (ja) * 2008-02-01 2011-04-07 アンコル インターナショナル コーポレイション 改良された皮膚美白組成物
CA2760186C (fr) 2009-04-28 2019-10-29 Foamix Ltd. Vehicule moussant et compositions pharmaceutiques comportant des solvants polaires aprotiques et leurs utilisations
WO2011013008A2 (fr) 2009-07-29 2011-02-03 Foamix Ltd. Compositions hydro-alcooliques moussantes à base d'agents non tensioactifs non polymères, mousses légères, et leurs utilisations
CA2769625C (fr) 2009-07-29 2017-04-11 Foamix Ltd. Compositions hydro-alcooliques moussantes non tensioactives, mousses legeres, et leurs utilisations
MX359879B (es) 2009-10-02 2018-10-12 Foamix Pharmaceuticals Ltd Composiciones tópicas de tetraciclina.
US9849142B2 (en) 2009-10-02 2017-12-26 Foamix Pharmaceuticals Ltd. Methods for accelerated return of skin integrity and for the treatment of impetigo
WO2012007843A2 (fr) 2010-07-12 2012-01-19 Foamix Ltd. Appareil et procédé pour éjecter une dose unitaire de contenu d'un récipient
CA2978573A1 (fr) 2016-09-08 2018-03-08 Foamix Pharmaceuticals Ltd. Compositions et methodes de traitement de la rosacee et de l'acnee
EP4322913A1 (fr) * 2021-04-16 2024-02-21 DSM IP Assets B.V. Formulation de rétinol (iii)
CN116251035A (zh) * 2023-03-17 2023-06-13 深圳市护家科技有限公司 一种含视黄醇和/或视黄醇衍生物的油性组合物

Citations (8)

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Publication number Priority date Publication date Assignee Title
US4966773A (en) * 1986-11-25 1990-10-30 Alcon Laboratories, Inc. Topical ophthalmic compositions containing microfine retinoid particles
EP0440398A1 (fr) * 1990-01-29 1991-08-07 JOHNSON & JOHNSON CONSUMER PRODUCTS, INC. Compositions pour les soins de la peau
CN1136431A (zh) * 1996-04-26 1996-11-27 朱宝义 粉刺霜
WO1998014167A1 (fr) * 1996-10-03 1998-04-09 Johnson & Johnson Consumer Companies, Inc. Compositions cosmetiques
EP0863161A2 (fr) * 1997-03-03 1998-09-09 Amcol International Corporation Procédé de préparation d'un copolymère adsorbant de l'eau et de l'huile capable d'encapsulation de particules solides et liquides et produits obtenus par ce procédé
US5851538A (en) * 1995-12-29 1998-12-22 Advanced Polymer Systems, Inc. Retinoid formulations in porous microspheres for reduced irritation and enhanced stability
US5891470A (en) * 1998-04-17 1999-04-06 Advanced Polymer Systems, Inc. Softgel formulation containing retinol
WO1999053904A2 (fr) * 1998-04-17 1999-10-28 Advanced Polymer Systems, Inc. Composition compatible avec un gel mou contenant du retinol

Patent Citations (8)

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Publication number Priority date Publication date Assignee Title
US4966773A (en) * 1986-11-25 1990-10-30 Alcon Laboratories, Inc. Topical ophthalmic compositions containing microfine retinoid particles
EP0440398A1 (fr) * 1990-01-29 1991-08-07 JOHNSON & JOHNSON CONSUMER PRODUCTS, INC. Compositions pour les soins de la peau
US5851538A (en) * 1995-12-29 1998-12-22 Advanced Polymer Systems, Inc. Retinoid formulations in porous microspheres for reduced irritation and enhanced stability
CN1136431A (zh) * 1996-04-26 1996-11-27 朱宝义 粉刺霜
WO1998014167A1 (fr) * 1996-10-03 1998-04-09 Johnson & Johnson Consumer Companies, Inc. Compositions cosmetiques
EP0863161A2 (fr) * 1997-03-03 1998-09-09 Amcol International Corporation Procédé de préparation d'un copolymère adsorbant de l'eau et de l'huile capable d'encapsulation de particules solides et liquides et produits obtenus par ce procédé
US5891470A (en) * 1998-04-17 1999-04-06 Advanced Polymer Systems, Inc. Softgel formulation containing retinol
WO1999053904A2 (fr) * 1998-04-17 1999-10-28 Advanced Polymer Systems, Inc. Composition compatible avec un gel mou contenant du retinol

Non-Patent Citations (3)

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Title
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; BACHTSI, ARISTI ET AL: "Development of biodegradable polymeric microparticles for the controlled delivery of bioactive agents", XP002201270, retrieved from STN Database accession no. 136:139747 *
DATABASE WPI Section Ch Week 199805, Derwent World Patents Index; Class B04, AN 1998-042637, XP002201271 *
RECENTS PROGRES EN GENIE DES PROCEDES (1999), 13(71), 327-334 *

Also Published As

Publication number Publication date
AU2001257534A1 (en) 2001-11-20
WO2001085102A8 (fr) 2003-11-20
EP1278504A2 (fr) 2003-01-29
CA2408137C (fr) 2011-04-19
WO2001085102A2 (fr) 2001-11-15
CA2408137A1 (fr) 2001-11-15
AR028085A1 (es) 2003-04-23

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