WO2001085637A3 - Biodegradable fiber optic - Google Patents

Biodegradable fiber optic Download PDF

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Publication number
WO2001085637A3
WO2001085637A3 PCT/US2001/014923 US0114923W WO0185637A3 WO 2001085637 A3 WO2001085637 A3 WO 2001085637A3 US 0114923 W US0114923 W US 0114923W WO 0185637 A3 WO0185637 A3 WO 0185637A3
Authority
WO
WIPO (PCT)
Prior art keywords
core
biodegradable
refraction
cladding
optical fiber
Prior art date
Application number
PCT/US2001/014923
Other languages
French (fr)
Other versions
WO2001085637A2 (en
Inventor
Paul J Weber
Brian D Andresen
Silva Luiz B Da
John P Wooldridge
Original Assignee
Pearl Technology Holdings Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pearl Technology Holdings Llc filed Critical Pearl Technology Holdings Llc
Priority to AU2001261300A priority Critical patent/AU2001261300A1/en
Publication of WO2001085637A2 publication Critical patent/WO2001085637A2/en
Publication of WO2001085637A3 publication Critical patent/WO2001085637A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/41—Detecting, measuring or recording for evaluating the immune or lymphatic systems
    • A61B5/413—Monitoring transplanted tissue or organ, e.g. for possible rejection reactions after a transplant
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G02B1/045—Light guides
    • G02B1/046—Light guides characterised by the core material
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B1/00—Optical elements characterised by the material of which they are made; Optical coatings for optical elements
    • G02B1/04—Optical elements characterised by the material of which they are made; Optical coatings for optical elements made of organic materials, e.g. plastics
    • G02B1/045—Light guides
    • G02B1/048—Light guides characterised by the cladding material
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B6/00—Light guides; Structural details of arrangements comprising light guides and other optical elements, e.g. couplings
    • G02B6/02—Optical fibres with cladding with or without a coating
    • G02B6/02033—Core or cladding made from organic material, e.g. polymeric material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532—Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4058—Detecting, measuring or recording for evaluating the nervous system for evaluating the central nervous system
    • A61B5/407—Evaluating the spinal cord

Abstract

An optical fiber includes a biodegradable core (12) with an index of refraction that is larger that the index of refraction of its surrounding medium or cladding (14). The biodegradable optical fiber may be formed from a variety of materials such as clear absorbable monofilamentous suture materials. The optical fiber (32) may include a biodegradable and biocompatible means for connecting to at least one other fiber optic (34). Embodiments of the core and cladding materials are given that will biodegrade when activated by heat, moisture, electromagnetic radiation, microbes, plants, animals and their enzymes, fluids or microbial or germ secretions. Many medical uses are provided, such as the inclusion of therapeutic agents embedded within the material of the core and/or the cladding where such agents will be released when the fiber begins to dissolve. An embodiment of the invention utilizes a medium of lower index of refraction through which the core passes to enable total internal reflection.
PCT/US2001/014923 2000-05-09 2001-05-08 Biodegradable fiber optic WO2001085637A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001261300A AU2001261300A1 (en) 2000-05-09 2001-05-08 Biodegradable fiber optic

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US56879600A 2000-05-09 2000-05-09
US09/568,796 2000-05-09

Publications (2)

Publication Number Publication Date
WO2001085637A2 WO2001085637A2 (en) 2001-11-15
WO2001085637A3 true WO2001085637A3 (en) 2002-04-25

Family

ID=24272779

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/014923 WO2001085637A2 (en) 2000-05-09 2001-05-08 Biodegradable fiber optic

Country Status (2)

Country Link
AU (1) AU2001261300A1 (en)
WO (1) WO2001085637A2 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6416800B1 (en) * 2000-08-04 2002-07-09 Pearl Technology Holdings, Llc Fiber optic candy
US7909773B2 (en) 2005-06-03 2011-03-22 Tyco Healthcare Group Lp Post-operative bacteria test strip spool and method
CA2704304C (en) 2006-11-03 2015-01-13 Trustees Of Trufts College Biopolymer optical waveguide and method of manufacturing the same
EP2086749B1 (en) 2006-11-03 2013-05-08 Trustees Of Tufts College Nanopatterned biopolymer optical device and method of manufacturing the same
EP2101975A2 (en) 2006-11-03 2009-09-23 Trustees of Tufts College Biopolymer sensor and method of manufacturing the same
WO2008118211A2 (en) 2006-11-03 2008-10-02 Trustees Of Tufts College Biopolymer photonic crystals and method of manufacturing the same
WO2009061823A1 (en) 2007-11-05 2009-05-14 Trustees Of Tufts College Fabrication of silk fibroin photonic structures by nanocontact imprinting
US8180421B2 (en) 2007-12-12 2012-05-15 Kimberly-Clark Worldwide, Inc. Resonance energy transfer based detection of nosocomial infection
US8280471B2 (en) 2007-12-12 2012-10-02 Kimberly-Clark Worldwide, Inc. Fiber optic based detection of autofluorescent bacterial pathogens
CA2789009C (en) 2009-02-12 2017-03-21 Trustees Of Tufts College Nanoimprinting of silk fibroin structures for biomedical and biophotonic applications
JP2012533780A (en) 2009-07-20 2012-12-27 タフツ ユニバーシティー／トラスティーズ オブ タフツ カレッジ Implantable absorptive reflector made of protein only
WO2011026101A2 (en) 2009-08-31 2011-03-03 Trustees Of Tufts College Silk transistor devices
WO2013032984A1 (en) * 2011-08-31 2013-03-07 The General Hospital Corporation Systems and methods for facilitating optical processes in a biological tissue
US9720167B2 (en) * 2015-02-20 2017-08-01 Elwha Llc Biodegradable optical fibers and methods of use thereof
US10241258B2 (en) 2017-04-18 2019-03-26 The Penn State Research Foundation Flexible biodegradable polymeric step-index optical fiber
US11129679B2 (en) 2017-11-14 2021-09-28 Mako Surgical Corp. Fiber optic tracking system
JP6579665B2 (en) * 2017-12-12 2019-09-25 呂路可 Biofiber device that guides light and aligns with tissue

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4604097A (en) * 1985-02-19 1986-08-05 University Of Dayton Bioabsorbable glass fibers for use in the reinforcement of bioabsorbable polymers for bone fixation devices and artificial ligaments
US4867531A (en) * 1988-02-29 1989-09-19 The Dow Chemical Company Plastic optical fiber for in vivo use having a biocompatible polysiloxane cladding
WO1993025202A1 (en) * 1992-06-05 1993-12-23 Arch Development Corporation Water and uv degradable lactic acid polymers
EP0595294A1 (en) * 1992-10-27 1994-05-04 United States Surgical Corporation Absorbable polymers and surgical articles made therefrom
WO1996011671A1 (en) * 1994-10-12 1996-04-25 Focal, Inc. Targeted delivery via biodegradable polymers
US5593778A (en) * 1993-09-09 1997-01-14 Kanebo, Ltd. Biodegradable copolyester, molded article produced therefrom and process for producing the molded article
US5688530A (en) * 1989-07-07 1997-11-18 Novartis Ag Sustained release formulations of water soluble peptides
JPH10298108A (en) * 1997-04-24 1998-11-10 Dainippon Ink & Chem Inc Bioabsorbable composite molded product, bioabsorbable material and their production
US5939191A (en) * 1993-06-11 1999-08-17 United States Surgical Corporation Coated gut suture
EP0982041A1 (en) * 1998-08-21 2000-03-01 Medtronic Ave, Inc. Thromboresistant coating using silanes or siloxanes
US6060582A (en) * 1992-02-28 2000-05-09 The Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US558896A (en) 1896-04-21 Chusetts

Patent Citations (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4604097A (en) * 1985-02-19 1986-08-05 University Of Dayton Bioabsorbable glass fibers for use in the reinforcement of bioabsorbable polymers for bone fixation devices and artificial ligaments
US4604097B1 (en) * 1985-02-19 1991-09-10 Univ Dayton
US4867531A (en) * 1988-02-29 1989-09-19 The Dow Chemical Company Plastic optical fiber for in vivo use having a biocompatible polysiloxane cladding
US5688530A (en) * 1989-07-07 1997-11-18 Novartis Ag Sustained release formulations of water soluble peptides
US6060582A (en) * 1992-02-28 2000-05-09 The Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
WO1993025202A1 (en) * 1992-06-05 1993-12-23 Arch Development Corporation Water and uv degradable lactic acid polymers
EP0595294A1 (en) * 1992-10-27 1994-05-04 United States Surgical Corporation Absorbable polymers and surgical articles made therefrom
US5939191A (en) * 1993-06-11 1999-08-17 United States Surgical Corporation Coated gut suture
US5593778A (en) * 1993-09-09 1997-01-14 Kanebo, Ltd. Biodegradable copolyester, molded article produced therefrom and process for producing the molded article
WO1996011671A1 (en) * 1994-10-12 1996-04-25 Focal, Inc. Targeted delivery via biodegradable polymers
JPH10298108A (en) * 1997-04-24 1998-11-10 Dainippon Ink & Chem Inc Bioabsorbable composite molded product, bioabsorbable material and their production
EP0982041A1 (en) * 1998-08-21 2000-03-01 Medtronic Ave, Inc. Thromboresistant coating using silanes or siloxanes

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PATENT ABSTRACTS OF JAPAN vol. 1999, no. 02 26 February 1999 (1999-02-26) *

Also Published As

Publication number Publication date
WO2001085637A2 (en) 2001-11-15
AU2001261300A1 (en) 2001-11-20

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