WO2001096608A8 - Detection of nucleic acids by type-specific hybrid capture method - Google Patents

Detection of nucleic acids by type-specific hybrid capture method

Info

Publication number
WO2001096608A8
WO2001096608A8 PCT/US2001/019353 US0119353W WO0196608A8 WO 2001096608 A8 WO2001096608 A8 WO 2001096608A8 US 0119353 W US0119353 W US 0119353W WO 0196608 A8 WO0196608 A8 WO 0196608A8
Authority
WO
WIPO (PCT)
Prior art keywords
hybrid capture
detection
type
specific hybrid
nucleic acids
Prior art date
Application number
PCT/US2001/019353
Other languages
French (fr)
Other versions
WO2001096608A1 (en
Inventor
James Anthony
Attila Lorincz
Inna Williams
John Troy
Yanglin Tang
Original Assignee
Digene Corp
James Anthony
Attila Lorincz
Inna Williams
John Troy
Yanglin Tang
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to EP01944578A priority Critical patent/EP1294944B1/en
Priority to AU6697401A priority patent/AU6697401A/en
Priority to US10/311,645 priority patent/US7645571B2/en
Priority to BRPI0111992-3A priority patent/BR0111992B1/en
Priority to JP2002510721A priority patent/JP5166666B2/en
Priority to AU2001266974A priority patent/AU2001266974B2/en
Application filed by Digene Corp, James Anthony, Attila Lorincz, Inna Williams, John Troy, Yanglin Tang filed Critical Digene Corp
Priority to CA2413020A priority patent/CA2413020C/en
Priority to AT01944578T priority patent/ATE548464T1/en
Publication of WO2001096608A1 publication Critical patent/WO2001096608A1/en
Publication of WO2001096608A8 publication Critical patent/WO2001096608A8/en
Priority to US12/622,160 priority patent/US8389219B2/en
Priority to US13/717,502 priority patent/US20130209990A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6832—Enhancement of hybridisation reaction
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/705—Specific hybridization probes for herpetoviridae, e.g. herpes simplex, varicella zoster
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/708—Specific hybridization probes for papilloma
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]

Abstract

Target-specific hybrid capture (TSHC) provides a nucleic acid detection method that is not only rapid and sensitive, but is also highly specific and capable of discriminating highly homologous nucleic acid target sequences. The method produces DNA/RNA hybrids which can be detected by a variety of methods.
PCT/US2001/019353 2000-06-15 2001-06-15 Detection of nucleic acids by type-specific hybrid capture method WO2001096608A1 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
AU6697401A AU6697401A (en) 2000-06-15 2001-06-15 Detection of nucleic acids by type-specific hybrid capture method
US10/311,645 US7645571B2 (en) 2000-06-15 2001-06-15 Detection of nucleic acids by type-specific hybrid capture method
BRPI0111992-3A BR0111992B1 (en) 2000-06-15 2001-06-15 Methods for detecting target nucleic acid by specific type hybrid capture
JP2002510721A JP5166666B2 (en) 2000-06-15 2001-06-15 For detecting nucleic acid by type-specific hybrid capture method
AU2001266974A AU2001266974B2 (en) 2000-06-15 2001-06-15 Detection of nucleic acids by type-specific hybrid capture method
EP01944578A EP1294944B1 (en) 2000-06-15 2001-06-15 Detection of nucleic acids by type-specific hybrid capture method
CA2413020A CA2413020C (en) 2000-06-15 2001-06-15 Detection of nucleic acids by type-specific hybrid capture method
AT01944578T ATE548464T1 (en) 2000-06-15 2001-06-15 DETECTION OF NUCLEIC ACIDS BY TYPE-SPECIFIC HYBRID-CAPTURE METHOD
US12/622,160 US8389219B2 (en) 2000-06-15 2009-11-19 Detection of nucleic acids by type-specific hybrid capture method
US13/717,502 US20130209990A1 (en) 2000-06-15 2012-12-17 Detection of nucleic acids by type-specific hybrid capture methods

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/594,839 2000-06-15
US09/594,839 US7439016B1 (en) 2000-06-15 2000-06-15 Detection of nucleic acids by type-specific hybrid capture method

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US09/594,839 Continuation-In-Part US7439016B1 (en) 2000-06-15 2000-06-15 Detection of nucleic acids by type-specific hybrid capture method

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US10311645 A-371-Of-International 2001-06-15
US12/622,160 Continuation US8389219B2 (en) 2000-06-15 2009-11-19 Detection of nucleic acids by type-specific hybrid capture method

Publications (2)

Publication Number Publication Date
WO2001096608A1 WO2001096608A1 (en) 2001-12-20
WO2001096608A8 true WO2001096608A8 (en) 2002-10-03

Family

ID=24380618

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/019353 WO2001096608A1 (en) 2000-06-15 2001-06-15 Detection of nucleic acids by type-specific hybrid capture method

Country Status (12)

Country Link
US (6) US7439016B1 (en)
EP (3) EP2308997B1 (en)
JP (2) JP5166666B2 (en)
AT (1) ATE548464T1 (en)
AU (2) AU6697401A (en)
BR (1) BR0111992B1 (en)
CA (2) CA2413020C (en)
DK (1) DK1967594T3 (en)
ES (1) ES2545183T3 (en)
PT (1) PT1967594E (en)
SI (1) SI1967594T1 (en)
WO (1) WO2001096608A1 (en)

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