WO2002000201A3 - Method for preparing a composition - Google Patents

Method for preparing a composition Download PDF

Info

Publication number
WO2002000201A3
WO2002000201A3 PCT/EP2001/006834 EP0106834W WO0200201A3 WO 2002000201 A3 WO2002000201 A3 WO 2002000201A3 EP 0106834 W EP0106834 W EP 0106834W WO 0200201 A3 WO0200201 A3 WO 0200201A3
Authority
WO
WIPO (PCT)
Prior art keywords
compositions
preparing
solution
homogeneous dispersion
relates
Prior art date
Application number
PCT/EP2001/006834
Other languages
French (fr)
Other versions
WO2002000201A2 (en
Inventor
Patrick Busson
Marco Schroeder
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8169074&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2002000201(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to AU8184601A priority Critical patent/AU8184601A/en
Priority to CA002411153A priority patent/CA2411153C/en
Priority to KR1020027017564A priority patent/KR100557845B1/en
Priority to EP01960323A priority patent/EP1296656B1/en
Priority to MEP-906/08A priority patent/MEP90608A/en
Priority to PL365803A priority patent/PL203804B1/en
Priority to BRPI0112014A priority patent/BRPI0112014B1/en
Priority to SI200130626T priority patent/SI1296656T1/en
Priority to AU2001281846A priority patent/AU2001281846B2/en
Priority to HU0302060A priority patent/HU229550B1/en
Priority to MXPA02012583A priority patent/MXPA02012583A/en
Priority to IL15328201A priority patent/IL153282A0/en
Priority to NZ523024A priority patent/NZ523024A/en
Priority to DE60121953T priority patent/DE60121953T2/en
Priority to JP2002504983A priority patent/JP4149803B2/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of WO2002000201A2 publication Critical patent/WO2002000201A2/en
Publication of WO2002000201A3 publication Critical patent/WO2002000201A3/en
Priority to IL153282A priority patent/IL153282A/en
Priority to HR20021009A priority patent/HRP20021009B1/en
Priority to NO20026197A priority patent/NO332181B1/en
Priority to HK04101186A priority patent/HK1058314A1/en
Priority to CY20061101498T priority patent/CY1105714T1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/122—Foams; Dry foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

The present invention relates to a method for the preparation of compositions, preferably pharmaceutical compositions, in form of expanded, mechanically stable, lamellar, porous, spongue-like or foam structures out of solutions and dispersions. This method comprises the steps of a) preparing a solution or a homogeneous dispersion of a liquid and a compound selected from the group consisting of one or more pharmaceutically active compounds, one or more pharmaceutically suitable excipients, and mixtures thereof, followed by b) the expansion of the solution or the homogeneous dispersion without boiling. The invention also relates to the compositions, their further processing and any corresponding dosage forms obtainable by the above method.
PCT/EP2001/006834 2000-06-27 2001-06-18 Method for preparing a composition WO2002000201A2 (en)

Priority Applications (20)

Application Number Priority Date Filing Date Title
CA002411153A CA2411153C (en) 2000-06-27 2001-06-18 Method for preparing a composition
IL15328201A IL153282A0 (en) 2000-06-27 2001-06-18 Method for preparing a pharmaceutical composition
MXPA02012583A MXPA02012583A (en) 2000-06-27 2001-06-18 Method for preparing a composition.
EP01960323A EP1296656B1 (en) 2000-06-27 2001-06-18 Method for preparing a composition
MEP-906/08A MEP90608A (en) 2000-06-27 2001-06-18 Method for preparing a composition
PL365803A PL203804B1 (en) 2000-06-27 2001-06-18 Method for preparing a composition
BRPI0112014A BRPI0112014B1 (en) 2000-06-27 2001-06-18 process for the preparation of a pharmaceutical composition in the form of sponge or foam-like structures and porous, and, pharmaceutical composition
SI200130626T SI1296656T1 (en) 2000-06-27 2001-06-18 Method for preparing a composition
AU2001281846A AU2001281846B2 (en) 2000-06-27 2001-06-18 Method for preparing a composition
NZ523024A NZ523024A (en) 2000-06-27 2001-06-18 Method for preparing a composition by expansion without boiling
KR1020027017564A KR100557845B1 (en) 2000-06-27 2001-06-18 Method for preparing a composition
AU8184601A AU8184601A (en) 2000-06-27 2001-06-18 Method for preparing a composition
HU0302060A HU229550B1 (en) 2000-06-27 2001-06-18 Method for preparing compositions
DE60121953T DE60121953T2 (en) 2000-06-27 2001-06-18 METHOD OF MANUFACTURING MEDICINE PREPARATIONS
JP2002504983A JP4149803B2 (en) 2000-06-27 2001-06-18 Method for preparing the composition
IL153282A IL153282A (en) 2000-06-27 2002-12-04 Method for preparing a pharmaceutical composition
HR20021009A HRP20021009B1 (en) 2000-06-27 2002-12-17 Method for preparing a composition
NO20026197A NO332181B1 (en) 2000-06-27 2002-12-23 Preparation and method of preparation of preparation
HK04101186A HK1058314A1 (en) 2000-06-27 2004-02-19 Method for preparing a composition
CY20061101498T CY1105714T1 (en) 2000-06-27 2006-10-19 METHOD FOR THE PREPARATION OF A COMPOSITION

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00113535.9 2000-06-27
EP00113535 2000-06-27

Publications (2)

Publication Number Publication Date
WO2002000201A2 WO2002000201A2 (en) 2002-01-03
WO2002000201A3 true WO2002000201A3 (en) 2002-04-18

Family

ID=8169074

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/006834 WO2002000201A2 (en) 2000-06-27 2001-06-18 Method for preparing a composition

Country Status (38)

Country Link
US (3) US6534087B2 (en)
EP (1) EP1296656B1 (en)
JP (2) JP4149803B2 (en)
KR (1) KR100557845B1 (en)
CN (1) CN1236764C (en)
AR (1) AR029278A1 (en)
AT (1) ATE334662T1 (en)
AU (2) AU2001281846B2 (en)
BR (1) BRPI0112014B1 (en)
CA (1) CA2411153C (en)
CY (1) CY1105714T1 (en)
CZ (1) CZ301813B6 (en)
DE (1) DE60121953T2 (en)
DK (1) DK1296656T3 (en)
EC (1) ECSP024401A (en)
EG (1) EG24141A (en)
ES (1) ES2269441T3 (en)
HK (1) HK1058314A1 (en)
HR (1) HRP20021009B1 (en)
HU (1) HU229550B1 (en)
IL (2) IL153282A0 (en)
JO (1) JO2247B1 (en)
MA (1) MA26922A1 (en)
ME (1) MEP90608A (en)
MX (1) MXPA02012583A (en)
MY (1) MY129798A (en)
NO (1) NO332181B1 (en)
NZ (1) NZ523024A (en)
PE (1) PE20020101A1 (en)
PL (1) PL203804B1 (en)
PT (1) PT1296656E (en)
RU (1) RU2244542C2 (en)
SI (1) SI1296656T1 (en)
TW (1) TWI278325B (en)
UY (1) UY26799A1 (en)
WO (1) WO2002000201A2 (en)
YU (1) YU96602A (en)
ZA (1) ZA200209649B (en)

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Also Published As

Publication number Publication date
BRPI0112014B1 (en) 2016-09-13
US20060134205A1 (en) 2006-06-22
CN1236764C (en) 2006-01-18
KR100557845B1 (en) 2006-03-10
MA26922A1 (en) 2004-12-20
DE60121953D1 (en) 2006-09-14
IL153282A (en) 2008-03-20
AU8184601A (en) 2002-01-08
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