WO2002014058A3 - Solid immersion lens structures and methods for producing solid immersion lens structures - Google Patents

Solid immersion lens structures and methods for producing solid immersion lens structures Download PDF

Info

Publication number
WO2002014058A3
WO2002014058A3 PCT/US2001/025030 US0125030W WO0214058A3 WO 2002014058 A3 WO2002014058 A3 WO 2002014058A3 US 0125030 W US0125030 W US 0125030W WO 0214058 A3 WO0214058 A3 WO 0214058A3
Authority
WO
WIPO (PCT)
Prior art keywords
solid immersion
immersion lens
lens structures
methods
lens
Prior art date
Application number
PCT/US2001/025030
Other languages
French (fr)
Other versions
WO2002014058A2 (en
Inventor
Olivier Legrand
Stephen R Quake
Original Assignee
California Inst Of Techn
Olivier Legrand
Stephen R Quake
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by California Inst Of Techn, Olivier Legrand, Stephen R Quake filed Critical California Inst Of Techn
Priority to AU2001283247A priority Critical patent/AU2001283247A1/en
Priority to JP2002519180A priority patent/JP2004505816A/en
Priority to EP01962032A priority patent/EP1349721A2/en
Publication of WO2002014058A2 publication Critical patent/WO2002014058A2/en
Publication of WO2002014058A3 publication Critical patent/WO2002014058A3/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
    • B29D11/00—Producing optical elements, e.g. lenses or prisms
    • B29D11/00009—Production of simple or compound lenses
    • B29D11/00365—Production of microlenses
    • B29D11/00394—Producing solid immersion lenses [SIL]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C33/00—Moulds or cores; Details thereof or accessories therefor
    • B29C33/44—Moulds or cores; Details thereof or accessories therefor with means for, or specially constructed to facilitate, the removal of articles, e.g. of undercut articles
    • B29C33/48—Moulds or cores; Details thereof or accessories therefor with means for, or specially constructed to facilitate, the removal of articles, e.g. of undercut articles with means for collapsing or disassembling
    • B29C33/50—Moulds or cores; Details thereof or accessories therefor with means for, or specially constructed to facilitate, the removal of articles, e.g. of undercut articles with means for collapsing or disassembling elastic or flexible
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C39/00—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor
    • B29C39/02—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor for making articles of definite length, i.e. discrete articles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C39/00—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor
    • B29C39/02—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor for making articles of definite length, i.e. discrete articles
    • B29C39/021—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor for making articles of definite length, i.e. discrete articles by casting in several steps
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C39/00—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor
    • B29C39/22—Component parts, details or accessories; Auxiliary operations
    • B29C39/36—Removing moulded articles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
    • B29D11/00—Producing optical elements, e.g. lenses or prisms
    • B29D11/00009—Production of simple or compound lenses
    • B29D11/00432—Auxiliary operations, e.g. machines for filling the moulds
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B3/00—Simple or compound lenses
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S359/00—Optical: systems and elements
    • Y10S359/90—Methods

Abstract

A microlens structure such as a solid immersion lens structure is a radiation transmissive pliant elastomer cast to a desired shape and smoothness. A method for construction of a solid immersion lens structure includes providing a mold defining a lens shaped cavity in which a solid immersion lens is cast, casting a translucent liquid elastomeric material into the lens cavity, permitting the elastomeric material to set to form the solid immersion lens portion and removing the solid immersion lens portion from the mold. A specific material for use as the solid immersion lens is a translucent silicone elastomer of a refractive index greater than n = 1.4.
PCT/US2001/025030 2000-08-16 2001-08-08 Solid immersion lens structures and methods for producing solid immersion lens structures WO2002014058A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2001283247A AU2001283247A1 (en) 2000-08-16 2001-08-08 Solid immersion lens structures and methods for producing solid immersion lens structures
JP2002519180A JP2004505816A (en) 2000-08-16 2001-08-08 Solid buried lens structure and method of manufacturing solid buried lens structure
EP01962032A EP1349721A2 (en) 2000-08-16 2001-08-08 Solid immersion lens structures and methods for producing solid immersion lens structures

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/640,907 2000-08-16
US09/640,907 US6301055B1 (en) 2000-08-16 2000-08-16 Solid immersion lens structures and methods for producing solid immersion lens structures

Publications (2)

Publication Number Publication Date
WO2002014058A2 WO2002014058A2 (en) 2002-02-21
WO2002014058A3 true WO2002014058A3 (en) 2003-07-24

Family

ID=24570169

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/025030 WO2002014058A2 (en) 2000-08-16 2001-08-08 Solid immersion lens structures and methods for producing solid immersion lens structures

Country Status (5)

Country Link
US (5) US6301055B1 (en)
EP (1) EP1349721A2 (en)
JP (1) JP2004505816A (en)
AU (1) AU2001283247A1 (en)
WO (1) WO2002014058A2 (en)

Families Citing this family (127)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6221654B1 (en) 1996-09-25 2001-04-24 California Institute Of Technology Method and apparatus for analysis and sorting of polynucleotides based on size
US7214298B2 (en) * 1997-09-23 2007-05-08 California Institute Of Technology Microfabricated cell sorter
US6958865B1 (en) 1998-11-12 2005-10-25 California Institute Of Technology Microlicensing particles and applications
US7459022B2 (en) 2001-04-06 2008-12-02 California Institute Of Technology Microfluidic protein crystallography
CA2721172C (en) * 1999-06-28 2012-04-10 California Institute Of Technology Microfabricated elastomeric valve and pump systems
US8052792B2 (en) * 2001-04-06 2011-11-08 California Institute Of Technology Microfluidic protein crystallography techniques
US8709153B2 (en) 1999-06-28 2014-04-29 California Institute Of Technology Microfludic protein crystallography techniques
US7306672B2 (en) 2001-04-06 2007-12-11 California Institute Of Technology Microfluidic free interface diffusion techniques
US7144616B1 (en) * 1999-06-28 2006-12-05 California Institute Of Technology Microfabricated elastomeric valve and pump systems
US7867763B2 (en) 2004-01-25 2011-01-11 Fluidigm Corporation Integrated chip carriers with thermocycler interfaces and methods of using the same
US20050118073A1 (en) * 2003-11-26 2005-06-02 Fluidigm Corporation Devices and methods for holding microfluidic devices
US7351376B1 (en) 2000-06-05 2008-04-01 California Institute Of Technology Integrated active flux microfluidic devices and methods
US6301055B1 (en) * 2000-08-16 2001-10-09 California Institute Of Technology Solid immersion lens structures and methods for producing solid immersion lens structures
EP1334347A1 (en) 2000-09-15 2003-08-13 California Institute Of Technology Microfabricated crossflow devices and methods
EP1343973B2 (en) 2000-11-16 2020-09-16 California Institute Of Technology Apparatus and methods for conducting assays and high throughput screening
US6635876B2 (en) * 2001-03-13 2003-10-21 Infocus Corporation Low-loss non-imaging optical concentrator for use in infrared remote control systems
US6602447B2 (en) * 2001-08-21 2003-08-05 Milliken & Company Low-color ultraviolet absorbers for high UV wavelength protection applications
WO2003031163A2 (en) 2001-10-08 2003-04-17 California Institute Of Technology Microfabricated lenses, methods of manufacture thereof, and applications therefor
US6804062B2 (en) * 2001-10-09 2004-10-12 California Institute Of Technology Nonimaging concentrator lens arrays and microfabrication of the same
US7691333B2 (en) * 2001-11-30 2010-04-06 Fluidigm Corporation Microfluidic device and methods of using same
EP1463796B1 (en) * 2001-11-30 2013-01-09 Fluidigm Corporation Microfluidic device and methods of using same
US6594086B1 (en) * 2002-01-16 2003-07-15 Optonics, Inc. (A Credence Company) Bi-convex solid immersion lens
JP4016179B2 (en) * 2002-02-28 2007-12-05 ソニー株式会社 Exposure apparatus and converging lens control method
EP1499706A4 (en) 2002-04-01 2010-11-03 Fluidigm Corp Microfluidic particle-analysis systems
US7123035B2 (en) * 2002-04-10 2006-10-17 Credence Systems Corporation Optics landing system and method therefor
US6700708B2 (en) 2002-05-30 2004-03-02 Agere Systems, Inc. Micro-lens array and method of making micro-lens array
US6683724B2 (en) 2002-06-13 2004-01-27 Eastman Kodak Company Solid immersion lens array and methods for producing a solid immersion lens array
JP2006507921A (en) * 2002-06-28 2006-03-09 プレジデント・アンド・フェロウズ・オブ・ハーバード・カレッジ Method and apparatus for fluid dispersion
EP1551753A2 (en) 2002-09-25 2005-07-13 California Institute Of Technology Microfluidic large scale integration
US8220494B2 (en) * 2002-09-25 2012-07-17 California Institute Of Technology Microfluidic large scale integration
JP5695287B2 (en) * 2002-10-02 2015-04-01 カリフォルニア インスティテュート オブ テクノロジー Nucleic acid analysis of microfluids
US6920203B2 (en) * 2002-12-02 2005-07-19 General Electric Company Method and apparatus for selectively attenuating a radiation source
JP4352874B2 (en) * 2002-12-10 2009-10-28 株式会社ニコン Exposure apparatus and device manufacturing method
CN100528517C (en) * 2002-12-13 2009-08-19 皇家飞利浦电子股份有限公司 Method of manufacturing a replica, as well as a replica obtained by carrying out a UV light-initiated or thermal curing treatment of a reactive mixture
JP4536654B2 (en) * 2003-03-20 2010-09-01 浜松ホトニクス株式会社 Solid immersion lens and microscope
TWI336777B (en) * 2003-03-20 2011-02-01 Hamamatsu Photonics Kk Solid immersion lens (sil) and specimen observation method by sil
US20060078893A1 (en) 2004-10-12 2006-04-13 Medical Research Council Compartmentalised combinatorial chemistry by microfluidic control
GB0307428D0 (en) 2003-03-31 2003-05-07 Medical Res Council Compartmentalised combinatorial chemistry
GB0307403D0 (en) 2003-03-31 2003-05-07 Medical Res Council Selection by compartmentalised screening
US7604965B2 (en) 2003-04-03 2009-10-20 Fluidigm Corporation Thermal reaction device and method for using the same
US8828663B2 (en) * 2005-03-18 2014-09-09 Fluidigm Corporation Thermal reaction device and method for using the same
EP1610888A2 (en) 2003-04-10 2006-01-04 President And Fellows Of Harvard College Formation and control of fluidic species
CA2526368A1 (en) 2003-05-20 2004-12-02 Fluidigm Corporation Method and system for microfluidic device and imaging thereof
EP2261741A3 (en) 2003-06-11 2011-05-25 ASML Netherlands B.V. Lithographic apparatus and device manufacturing method
US7317504B2 (en) * 2004-04-08 2008-01-08 Asml Netherlands B.V. Lithographic apparatus and device manufacturing method
US7042649B2 (en) * 2003-08-11 2006-05-09 California Institute Of Technology Microfabricated rubber microscope using soft solid immersion lenses
BRPI0414004A (en) * 2003-08-27 2006-10-24 Harvard College electronic control of fluidic species
US7407799B2 (en) 2004-01-16 2008-08-05 California Institute Of Technology Microfluidic chemostat
US20050221339A1 (en) 2004-03-31 2005-10-06 Medical Research Council Harvard University Compartmentalised screening by microfluidic control
US7248265B2 (en) * 2004-04-16 2007-07-24 Apple Inc. System and method for processing graphics operations with graphics processing unit
JP4911722B2 (en) * 2004-06-07 2012-04-04 フルイディグム コーポレイション Optical lens system and method for microfluidic devices
US9477233B2 (en) 2004-07-02 2016-10-25 The University Of Chicago Microfluidic system with a plurality of sequential T-junctions for performing reactions in microdroplets
US8187772B2 (en) * 2004-10-08 2012-05-29 Globalfoundries Inc. Solid immersion lens lithography
US7968287B2 (en) 2004-10-08 2011-06-28 Medical Research Council Harvard University In vitro evolution in microfluidic systems
JP2008522795A (en) * 2004-12-03 2008-07-03 カリフォルニア インスティチュート オブ テクノロジー Microfluidic device with chemical reaction circuit
WO2006060748A2 (en) 2004-12-03 2006-06-08 California Institute Of Technology Microfluidic sieve valves
US7880860B2 (en) 2004-12-20 2011-02-01 Asml Netherlands B.V. Lithographic apparatus and device manufacturing method
FI20055043A0 (en) * 2005-01-31 2005-01-31 Wallac Oy Arrangements at an imaging device for microtiter wells
CA2599683A1 (en) 2005-03-04 2006-09-14 President And Fellows Of Harvard College Method and apparatus for forming multiple emulsions
US20070054119A1 (en) * 2005-03-04 2007-03-08 Piotr Garstecki Systems and methods of forming particles
WO2006127191A2 (en) 2005-04-20 2006-11-30 Fluidigm Corporation Analysis engine and database for manipulating parameters for fluidic systems on a chip
US20070054293A1 (en) * 2005-08-30 2007-03-08 California Institute Of Technology Microfluidic chaotic mixing systems and methods
EP1938101A2 (en) * 2005-09-13 2008-07-02 Fluidigm Corporation Microfluidic assay devices and methods
EP2363205A3 (en) 2006-01-11 2014-06-04 Raindance Technologies, Inc. Microfluidic Devices And Methods Of Use In The Formation And Control Of Nanoreactors
DE602007009811D1 (en) * 2006-01-27 2010-11-25 Harvard College COALESCENCE FLUIDER DROPLET
US7815868B1 (en) * 2006-02-28 2010-10-19 Fluidigm Corporation Microfluidic reaction apparatus for high throughput screening
US8828661B2 (en) 2006-04-24 2014-09-09 Fluidigm Corporation Methods for detection and quantification of nucleic acid or protein targets in a sample
EP2530168B1 (en) 2006-05-11 2015-09-16 Raindance Technologies, Inc. Microfluidic Devices
US9562837B2 (en) 2006-05-11 2017-02-07 Raindance Technologies, Inc. Systems for handling microfludic droplets
WO2008000414A1 (en) * 2006-06-26 2008-01-03 Novartis Ag Method and apparatus for manufacturing ophthalmic lenses
WO2008021123A1 (en) 2006-08-07 2008-02-21 President And Fellows Of Harvard College Fluorocarbon emulsion stabilizing surfactants
US8737178B2 (en) * 2006-09-05 2014-05-27 Seagate Technology Llc Alignment feature for near-field transducers
US8055034B2 (en) 2006-09-13 2011-11-08 Fluidigm Corporation Methods and systems for image processing of microfluidic devices
US7858156B2 (en) * 2006-11-27 2010-12-28 The University Of Massachusetts Surface buckling method and articles formed thereby
WO2008067552A2 (en) * 2006-11-30 2008-06-05 Fluidigm Corporation Method and apparatus for biological sample analysis
EP1931158B1 (en) * 2006-12-08 2013-04-10 Samsung Electronics Co., Ltd. Apparatus and method for selecting frame structure in multihop relay broadband wireless access communication system
US8157434B2 (en) * 2007-01-19 2012-04-17 Fluidigm Corporation High efficiency and high precision microfluidic devices and methods
WO2008097559A2 (en) 2007-02-06 2008-08-14 Brandeis University Manipulation of fluids and reactions in microfluidic systems
US8654305B2 (en) 2007-02-15 2014-02-18 Asml Holding N.V. Systems and methods for insitu lens cleaning in immersion lithography
US8817226B2 (en) 2007-02-15 2014-08-26 Asml Holding N.V. Systems and methods for insitu lens cleaning using ozone in immersion lithography
JPWO2008117651A1 (en) * 2007-03-26 2010-07-15 コニカミノルタオプト株式会社 Microchip
CN102014871A (en) * 2007-03-28 2011-04-13 哈佛大学 Emulsions and techniques for formation
WO2008130623A1 (en) 2007-04-19 2008-10-30 Brandeis University Manipulation of fluids, fluid components and reactions in microfluidic systems
BRPI0816393A2 (en) 2007-09-07 2015-03-03 Fluidigm Corp METHOD FOR DETERMINING THE NUMBER OF COPIES REGARDING A TARGET POLINUCLEOTIDE SEQUENCE IN A GENOME OF AN INDIVIDUAL
US20090159126A1 (en) * 2007-12-22 2009-06-25 Solfocus, Inc. Integrated optics for concentrator solar receivers
WO2009100449A1 (en) 2008-02-08 2009-08-13 Fluidigm Corporation Dynamic array assay methods
CN102056838B (en) 2008-04-11 2013-07-03 弗卢丁公司 Microfluidic device and methods
US8906284B2 (en) * 2008-05-28 2014-12-09 The University Of Massachusetts Wrinkled adhesive surfaces and methods for the preparation thereof
EP4047367A1 (en) 2008-07-18 2022-08-24 Bio-Rad Laboratories, Inc. Method for detecting target analytes with droplet libraries
WO2010011852A1 (en) 2008-07-25 2010-01-28 Fluidigm Corporation Method and system for manufacturing integrated fluidic chips
WO2010017210A1 (en) 2008-08-07 2010-02-11 Fluidigm Corporation Microfluidic mixing and reaction systems for high efficiency screening
US8058630B2 (en) 2009-01-16 2011-11-15 Fluidigm Corporation Microfluidic devices and methods
EP3415235A1 (en) 2009-03-23 2018-12-19 Raindance Technologies Inc. Manipulation of microfluidic droplets
WO2010124028A2 (en) 2009-04-21 2010-10-28 Vasylyev Sergiy V Light collection and illumination systems employing planar waveguide
US8551787B2 (en) * 2009-07-23 2013-10-08 Fluidigm Corporation Microfluidic devices and methods for binary mixing
EP2473263B1 (en) 2009-09-02 2022-11-02 President and Fellows of Harvard College Multiple emulsions created using jetting and other techniques
SG169918A1 (en) 2009-10-02 2011-04-29 Fluidigm Corp Microfluidic devices with removable cover and methods of fabrication and application
WO2011042564A1 (en) 2009-10-09 2011-04-14 Universite De Strasbourg Labelled silica-based nanomaterial with enhanced properties and uses thereof
US8325420B2 (en) * 2009-11-24 2012-12-04 Massachusetts Institute Of Technology Annular solid immersion lenses and methods of making them
CA2782181A1 (en) 2009-11-30 2011-06-03 Fluidigm Corporation Microfluidic device regeneration
EP2517025B1 (en) 2009-12-23 2019-11-27 Bio-Rad Laboratories, Inc. Methods for reducing the exchange of molecules between droplets
US9399797B2 (en) 2010-02-12 2016-07-26 Raindance Technologies, Inc. Digital analyte analysis
US9366632B2 (en) 2010-02-12 2016-06-14 Raindance Technologies, Inc. Digital analyte analysis
EP2534267B1 (en) 2010-02-12 2018-04-11 Raindance Technologies, Inc. Digital analyte analysis
US10351905B2 (en) 2010-02-12 2019-07-16 Bio-Rad Laboratories, Inc. Digital analyte analysis
BR112012023441A2 (en) * 2010-03-17 2016-05-24 Basf Se fusion emulsification
US8907312B2 (en) * 2010-08-20 2014-12-09 Bio-Rad Laboratories, Inc. Cytometry system with solid numerical-aperture-increasing lens
US9562897B2 (en) 2010-09-30 2017-02-07 Raindance Technologies, Inc. Sandwich assays in droplets
US9353406B2 (en) 2010-10-22 2016-05-31 Fluidigm Corporation Universal probe assay methods
US9364803B2 (en) 2011-02-11 2016-06-14 Raindance Technologies, Inc. Methods for forming mixed droplets
US9150852B2 (en) 2011-02-18 2015-10-06 Raindance Technologies, Inc. Compositions and methods for molecular labeling
US8618518B2 (en) 2011-03-15 2013-12-31 Avago Technologies General Ip (Singapore) Pte. Ltd. Apparatus and method for forming a solid immersion lens using a binary bitmap milling pattern
US9168531B2 (en) 2011-03-24 2015-10-27 Fluidigm Corporation Method for thermal cycling of microfluidic samples
US9644231B2 (en) 2011-05-09 2017-05-09 Fluidigm Corporation Nucleic acid detection using probes
CN108342453A (en) 2011-05-09 2018-07-31 富鲁达公司 Detection of nucleic acids based on probe
WO2012162296A2 (en) 2011-05-23 2012-11-29 President And Fellows Of Harvard College Control of emulsions, including multiple emulsions
EP3709018A1 (en) 2011-06-02 2020-09-16 Bio-Rad Laboratories, Inc. Microfluidic apparatus for identifying components of a chemical reaction
US8841071B2 (en) 2011-06-02 2014-09-23 Raindance Technologies, Inc. Sample multiplexing
WO2013006661A2 (en) 2011-07-06 2013-01-10 President And Fellows Of Harvard College Multiple emulsions and techniques for the formation of multiple emulsions
US8658430B2 (en) 2011-07-20 2014-02-25 Raindance Technologies, Inc. Manipulating droplet size
US11901041B2 (en) 2013-10-04 2024-02-13 Bio-Rad Laboratories, Inc. Digital analysis of nucleic acid modification
US9944977B2 (en) 2013-12-12 2018-04-17 Raindance Technologies, Inc. Distinguishing rare variations in a nucleic acid sequence from a sample
US11193176B2 (en) 2013-12-31 2021-12-07 Bio-Rad Laboratories, Inc. Method for detecting and quantifying latent retroviral RNA species
WO2015138647A1 (en) 2014-03-11 2015-09-17 Dcg Systems, Inc. Self correcting floating sil tip
EP3277153A4 (en) * 2015-03-30 2019-03-27 Invuity, Inc. Malleable waveguide
WO2016178975A1 (en) * 2015-05-01 2016-11-10 SuRe Optics, Inc. Optical imaging systems with microlens array with integral structure
US10647981B1 (en) 2015-09-08 2020-05-12 Bio-Rad Laboratories, Inc. Nucleic acid library generation methods and compositions

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4155962A (en) * 1977-05-25 1979-05-22 Neefe Optical Laboratory, Inc. Method of removing molded lenses from the mold
EP0362993A2 (en) * 1988-10-05 1990-04-11 Hewlett-Packard Company Nonimaging light source
US5121256A (en) * 1991-03-14 1992-06-09 The Board Of Trustees Of The Leland Stanford Junior University Lithography system employing a solid immersion lens
US5171995A (en) * 1990-09-28 1992-12-15 Bruker Analytische Mebtechnik Gmbh Sample holder for optical spectrometer and method for taking a spectrum
WO1998019854A1 (en) * 1996-11-06 1998-05-14 Bausch & Lomb Incorporated Method and apparatus for separating contact lens mold sections
JPH11197587A (en) * 1998-01-19 1999-07-27 Ishikawajima Harima Heavy Ind Co Ltd Device for masking blade component
US5939709A (en) * 1997-06-19 1999-08-17 Ghislain; Lucien P. Scanning probe optical microscope using a solid immersion lens

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2528339C3 (en) 1975-06-25 1979-01-18 Konishiroku Photo Ind. Co. Ltd., Tokio Electrophotographic suspension developer
US5776191A (en) * 1982-02-05 1998-07-07 Staar Surgical Company Fixation system for intraocular lens structures
US4540534A (en) 1983-10-11 1985-09-10 American Optical Corporation Apparatus and method for injection molding lenses
US4798428A (en) * 1986-10-14 1989-01-17 Ncr Corporation Fiber optic coupling system
US5317452A (en) * 1992-11-17 1994-05-31 Harvard University Aligning and attaching a lens to a source of emitted light using light pressure force
GB2277405A (en) * 1993-04-22 1994-10-26 Sharp Kk Semiconductor colour display or detector array
JPH081810A (en) 1994-06-20 1996-01-09 Koichi Ishida Microlens formed by isotropic etching
JPH08315404A (en) * 1995-05-18 1996-11-29 Sony Corp Optical pickup device
US6200737B1 (en) * 1995-08-24 2001-03-13 Trustees Of Tufts College Photodeposition method for fabricating a three-dimensional, patterned polymer microstructure
US5792610A (en) * 1996-05-01 1998-08-11 Biorad Laboratories, Inc. Method for conducting multiparametric fluorescence in situ hybridization
US5729393A (en) * 1996-04-03 1998-03-17 Digital Papyrus Corporation Optical flying head with solid immersion lens having raised central surface facing medium
US6270696B1 (en) * 1996-06-03 2001-08-07 Terastor Corporation Method of fabricating and integrating an optical assembly into a flying head
JP2986552B2 (en) 1996-11-04 1999-12-06 ザ、プロクター、エンド、ギャンブル、カンパニー Hair mousse composition containing silicone emulsion
US5815306A (en) * 1996-12-24 1998-09-29 Xerox Corporation "Eggcrate" substrate for a twisting ball display
CA2306384A1 (en) * 1997-10-14 1999-04-22 Patterning Technologies Limited Method of forming an electronic device
JPH11203715A (en) * 1998-01-14 1999-07-30 Pioneer Electron Corp Production of optical master disk
US6687196B1 (en) * 1998-05-08 2004-02-03 Fuji Xerox Co., Lt.D. Method and apparatus for implementing high density recording on a recording medium and a method of manufacturing same
JP3972484B2 (en) * 1998-09-16 2007-09-05 コニカミノルタオプト株式会社 Solid immersion lens
JP2000099987A (en) * 1998-09-24 2000-04-07 Sanyo Electric Co Ltd Magneto-optical head device
KR20010033374A (en) * 1998-10-21 2001-04-25 이데이 노부유끼 Optical head and drive device for optical recording medium
WO2000028598A1 (en) * 1998-11-10 2000-05-18 Biocrystal Limited Methods for identification and verification
US6614598B1 (en) * 1998-11-12 2003-09-02 Institute Of Technology, California Microlensing particles and applications
JP2000223767A (en) * 1999-02-01 2000-08-11 Agency Of Ind Science & Technol Proximity field light generating element and optical head
US6608716B1 (en) * 1999-05-17 2003-08-19 New Mexico State University Technology Transfer Corporation Optical enhancement with nanoparticles and microcavities
US6236513B1 (en) * 1999-06-30 2001-05-22 Quantum Corporation Integrated objective/solid immersion lens for near field recording
US6181478B1 (en) * 1999-07-16 2001-01-30 Michael Mandella Ellipsoidal solid immersion lens
JP2001043557A (en) * 1999-07-28 2001-02-16 Minolta Co Ltd Optical head and its manufacture
US6301055B1 (en) * 2000-08-16 2001-10-09 California Institute Of Technology Solid immersion lens structures and methods for producing solid immersion lens structures
WO2003008943A1 (en) * 2001-07-19 2003-01-30 Tufts University Optical array device and methods of use thereof for screening, analysis and manipulation of particles
TWI236010B (en) * 2003-01-09 2005-07-11 Univ Nat Chiao Tung Manufacturing method to associate solid immersion lens and nanometer aperture, and device thereof
US7042649B2 (en) * 2003-08-11 2006-05-09 California Institute Of Technology Microfabricated rubber microscope using soft solid immersion lenses

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4155962A (en) * 1977-05-25 1979-05-22 Neefe Optical Laboratory, Inc. Method of removing molded lenses from the mold
EP0362993A2 (en) * 1988-10-05 1990-04-11 Hewlett-Packard Company Nonimaging light source
US5171995A (en) * 1990-09-28 1992-12-15 Bruker Analytische Mebtechnik Gmbh Sample holder for optical spectrometer and method for taking a spectrum
US5121256A (en) * 1991-03-14 1992-06-09 The Board Of Trustees Of The Leland Stanford Junior University Lithography system employing a solid immersion lens
WO1998019854A1 (en) * 1996-11-06 1998-05-14 Bausch & Lomb Incorporated Method and apparatus for separating contact lens mold sections
US5939709A (en) * 1997-06-19 1999-08-17 Ghislain; Lucien P. Scanning probe optical microscope using a solid immersion lens
JPH11197587A (en) * 1998-01-19 1999-07-27 Ishikawajima Harima Heavy Ind Co Ltd Device for masking blade component

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PATENT ABSTRACTS OF JAPAN vol. 1999, no. 12 29 October 1999 (1999-10-29) *

Also Published As

Publication number Publication date
AU2001283247A1 (en) 2002-02-25
US6560030B2 (en) 2003-05-06
US20040027707A1 (en) 2004-02-12
US20050036222A1 (en) 2005-02-17
EP1349721A2 (en) 2003-10-08
US20020034027A1 (en) 2002-03-21
WO2002014058A2 (en) 2002-02-21
US7161736B2 (en) 2007-01-09
US6301055B1 (en) 2001-10-09
US20020024728A1 (en) 2002-02-28
US6836384B2 (en) 2004-12-28
JP2004505816A (en) 2004-02-26
US6608726B2 (en) 2003-08-19

Similar Documents

Publication Publication Date Title
WO2002014058A3 (en) Solid immersion lens structures and methods for producing solid immersion lens structures
DE69631843D1 (en) METHOD FOR PRODUCING A DENTAL PROSTHESIS
DE60111190D1 (en) METHOD AND DEVICE FOR PRODUCING CAST FOAM BODIES
DE60219031D1 (en) METHOD FOR THE PRODUCTION OF CASTINGS
BR0108671A (en) Methods for shaping an ophthalmic implant and intraocular lens, intraocular implant and lens and molds for casting an intraocular implant
DK504087A (en) CASTING OF CONTACT LENSES
MY125278A (en) Replica molding
DE59812979D1 (en) FORM FOR THE MANUFACTURE OF A TOOTH MODEL
CA2178910A1 (en) Method for making an intraocular implant with a soft lens
DK0668062T3 (en) Method of making a bone prosthesis with directly molded macro-extruded surface areas
WO1992006833A3 (en) Method for forming disposable molds for producing optical quality lenses
DE69904885D1 (en) Casting mold for the production of ophthalmic lenses
MX9705217A (en) Method for enclosing an object with a transparent encapsulation.
BR0200894A (en) Die casting method and die casting apparatus
ATE229305T1 (en) RANGE OF MOLDING ELEMENTS FOR PRODUCING PLASTER MODELS FOR DENTAL PROStheses, AND MOLDING SYSTEMS USING THESE ELEMENTS
DK0738192T3 (en) Molding for as well as casting and cooling stretching at a string molding plant
EP1043363A3 (en) Mother mold-forming silicone rubber composition and mother mold obtainable therefrom
CA2155112A1 (en) Artificial airway device
EP0836110A3 (en) Toric surface casting
AU6449800A (en) Method for moulding ophthalmic lenses
ATE146708T1 (en) VERTICALLY SPLIT FORM WITH FEEDER
JPS57212401A (en) High refractive index plastic lens
WO2005081837A3 (en) Method for casting thermosets with polyurethane molds
EP1025810A3 (en) Cast for embedding patterns in mould material for the production of moulds for dental workpieces
JPS6484219A (en) Production of contact lens

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2002519180

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: 2001962032

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWP Wipo information: published in national office

Ref document number: 2001962032

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 2001962032

Country of ref document: EP