WO2002028901A3 - Seven-transmembrane (7tm) receptors and uses thereof - Google Patents

Seven-transmembrane (7tm) receptors and uses thereof Download PDF

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Publication number
WO2002028901A3
WO2002028901A3 PCT/US2001/031250 US0131250W WO0228901A3 WO 2002028901 A3 WO2002028901 A3 WO 2002028901A3 US 0131250 W US0131250 W US 0131250W WO 0228901 A3 WO0228901 A3 WO 0228901A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
acid molecules
expression vectors
receptors
provides isolated
Prior art date
Application number
PCT/US2001/031250
Other languages
French (fr)
Other versions
WO2002028901A2 (en
Inventor
Maria Alexandra Gluckmann
Original Assignee
Millennium Pharm Inc
Maria Alexandra Gluckmann
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharm Inc, Maria Alexandra Gluckmann filed Critical Millennium Pharm Inc
Priority to AU2001296650A priority Critical patent/AU2001296650A1/en
Publication of WO2002028901A2 publication Critical patent/WO2002028901A2/en
Publication of WO2002028901A3 publication Critical patent/WO2002028901A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The invention provides isolated nucleic acids molecules, designated 65499 and 58875 nucleic acid molecules, which encode novel seven transmembrane domain (7TM) receptors, e.g., G-protein coupled receptor family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 65499 or 58875 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 65499 or 58875 gene has been intrtoduced or disrupted. The inveniton still further provides isolated 65499 or 58875 proteins, fusion proteins, antigenic peptides and anti-65499 or 58875 antibodies. Diagnostic methods utilizing of the invention are also provided.
PCT/US2001/031250 2000-10-05 2001-10-03 Seven-transmembrane (7tm) receptors and uses thereof WO2002028901A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001296650A AU2001296650A1 (en) 2000-10-05 2001-10-03 Seven-transmembrane (7tm) receptors and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23770000P 2000-10-05 2000-10-05
US60/237,700 2000-10-05

Publications (2)

Publication Number Publication Date
WO2002028901A2 WO2002028901A2 (en) 2002-04-11
WO2002028901A3 true WO2002028901A3 (en) 2003-04-17

Family

ID=22894785

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/031250 WO2002028901A2 (en) 2000-10-05 2001-10-03 Seven-transmembrane (7tm) receptors and uses thereof

Country Status (3)

Country Link
US (1) US20030148281A1 (en)
AU (1) AU2001296650A1 (en)
WO (1) WO2002028901A2 (en)

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US20030027135A1 (en) 2001-03-02 2003-02-06 Ecker David J. Method for rapid detection and identification of bioagents
US7226739B2 (en) 2001-03-02 2007-06-05 Isis Pharmaceuticals, Inc Methods for rapid detection and identification of bioagents in epidemiological and forensic investigations
US20040121309A1 (en) 2002-12-06 2004-06-24 Ecker David J. Methods for rapid detection and identification of bioagents in blood, bodily fluids, and bodily tissues
US7666588B2 (en) 2001-03-02 2010-02-23 Ibis Biosciences, Inc. Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy
US8073627B2 (en) 2001-06-26 2011-12-06 Ibis Biosciences, Inc. System for indentification of pathogens
US7217510B2 (en) 2001-06-26 2007-05-15 Isis Pharmaceuticals, Inc. Methods for providing bacterial bioagent characterizing information
CA2508726A1 (en) 2002-12-06 2004-07-22 Isis Pharmaceuticals, Inc. Methods for rapid identification of pathogens in humans and animals
US8046171B2 (en) 2003-04-18 2011-10-25 Ibis Biosciences, Inc. Methods and apparatus for genetic evaluation
US8057993B2 (en) 2003-04-26 2011-11-15 Ibis Biosciences, Inc. Methods for identification of coronaviruses
US7964343B2 (en) 2003-05-13 2011-06-21 Ibis Biosciences, Inc. Method for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
US8158354B2 (en) 2003-05-13 2012-04-17 Ibis Biosciences, Inc. Methods for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
US7956175B2 (en) 2003-09-11 2011-06-07 Ibis Biosciences, Inc. Compositions for use in identification of bacteria
US8097416B2 (en) 2003-09-11 2012-01-17 Ibis Biosciences, Inc. Methods for identification of sepsis-causing bacteria
US8546082B2 (en) 2003-09-11 2013-10-01 Ibis Biosciences, Inc. Methods for identification of sepsis-causing bacteria
US7666592B2 (en) 2004-02-18 2010-02-23 Ibis Biosciences, Inc. Methods for concurrent identification and quantification of an unknown bioagent
US8119336B2 (en) 2004-03-03 2012-02-21 Ibis Biosciences, Inc. Compositions for use in identification of alphaviruses
WO2005117270A2 (en) 2004-05-24 2005-12-08 Isis Pharmaceuticals, Inc. Mass spectrometry with selective ion filtration by digital thresholding
US20050266411A1 (en) 2004-05-25 2005-12-01 Hofstadler Steven A Methods for rapid forensic analysis of mitochondrial DNA
US7811753B2 (en) 2004-07-14 2010-10-12 Ibis Biosciences, Inc. Methods for repairing degraded DNA
WO2006135400A2 (en) 2004-08-24 2006-12-21 Isis Pharmaceuticals, Inc. Methods for rapid identification of recombinant organisms
US8084207B2 (en) 2005-03-03 2011-12-27 Ibis Bioscience, Inc. Compositions for use in identification of papillomavirus
WO2006094238A2 (en) 2005-03-03 2006-09-08 Isis Pharmaceuticals, Inc. Compositions for use in identification of adventitious viruses
JP5162447B2 (en) * 2005-04-13 2013-03-13 アイビス バイオサイエンシズ インコーポレイティッド Composition for use in adenovirus identification
CA2616281C (en) 2005-07-21 2014-04-22 Isis Pharmaceuticals, Inc. Methods for rapid identification and quantitation of mitochondrial dna variants
AU2007353877B2 (en) 2006-09-14 2012-07-19 Ibis Biosciences, Inc. Targeted whole genome amplification method for identification of pathogens
WO2008104002A2 (en) 2007-02-23 2008-08-28 Ibis Biosciences, Inc. Methods for rapid forensic dna analysis
US9598724B2 (en) 2007-06-01 2017-03-21 Ibis Biosciences, Inc. Methods and compositions for multiple displacement amplification of nucleic acids
US8148163B2 (en) 2008-09-16 2012-04-03 Ibis Biosciences, Inc. Sample processing units, systems, and related methods
WO2010033599A2 (en) 2008-09-16 2010-03-25 Ibis Biosciences, Inc. Mixing cartridges, mixing stations, and related kits, systems, and methods
US8534447B2 (en) 2008-09-16 2013-09-17 Ibis Biosciences, Inc. Microplate handling systems and related computer program products and methods
EP2396803A4 (en) 2009-02-12 2016-10-26 Ibis Biosciences Inc Ionization probe assemblies
EP2454000A4 (en) 2009-07-17 2016-08-10 Ibis Biosciences Inc Systems for bioagent identification
US8950604B2 (en) 2009-07-17 2015-02-10 Ibis Biosciences, Inc. Lift and mount apparatus
EP2957641B1 (en) 2009-10-15 2017-05-17 Ibis Biosciences, Inc. Multiple displacement amplification

Citations (3)

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DE10004930A1 (en) * 2000-02-04 2001-08-09 Michael Brues Gene encoding a protein of the G protein receptor super family, having homology to neurotransmitter receptors is useful to develop new medicaments
WO2001088126A2 (en) * 2000-05-15 2001-11-22 Bayer Aktiengesellschaft REGULATION OF HUMAN α1Α ADRENERGIC RECEPTOR-LIKE G PROTEIN-COUPLED RECEPTOR

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999032519A1 (en) * 1997-12-22 1999-07-01 Astrazeneca Canada Inc. Novel g protein-coupled receptor
DE10004930A1 (en) * 2000-02-04 2001-08-09 Michael Brues Gene encoding a protein of the G protein receptor super family, having homology to neurotransmitter receptors is useful to develop new medicaments
WO2001088126A2 (en) * 2000-05-15 2001-11-22 Bayer Aktiengesellschaft REGULATION OF HUMAN α1Α ADRENERGIC RECEPTOR-LIKE G PROTEIN-COUPLED RECEPTOR

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
LEE DENNIS K ET AL: "Discovery and mapping of ten novel G protein-coupled receptor genes.", GENE (AMSTERDAM), vol. 275, no. 1, 5 September 2001 (2001-09-05), pages 83 - 91, XP004307114, ISSN: 0378-1119 *
MARCHESE A ET AL: "Novel GPCRs and their endogenous ligands: expanding the boundaries of physiology and pharmacology", TRENDS IN PHARMACOLOGICAL SCIENCES, ELSEVIER TRENDS JOURNAL, CAMBRIDGE, GB, vol. 20, no. 9, 1 September 1999 (1999-09-01), pages 370 - 375, XP004178194, ISSN: 0165-6147 *

Also Published As

Publication number Publication date
AU2001296650A1 (en) 2002-04-15
WO2002028901A2 (en) 2002-04-11
US20030148281A1 (en) 2003-08-07

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