WO2002042780A3 - Apparatus and methods for separating agglutinants and disperse particles - Google Patents
Apparatus and methods for separating agglutinants and disperse particles Download PDFInfo
- Publication number
- WO2002042780A3 WO2002042780A3 PCT/US2001/043373 US0143373W WO0242780A3 WO 2002042780 A3 WO2002042780 A3 WO 2002042780A3 US 0143373 W US0143373 W US 0143373W WO 0242780 A3 WO0242780 A3 WO 0242780A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- methods
- disperse particles
- separation zone
- gaps
- agglutinants
- Prior art date
Links
- 239000002245 particle Substances 0.000 title abstract 3
- 238000000926 separation method Methods 0.000 abstract 3
- 239000007787 solid Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/04—Investigating sedimentation of particle suspensions
- G01N15/05—Investigating sedimentation of particle suspensions in blood
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502753—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by bulk separation arrangements on lab-on-a-chip devices, e.g. for filtration or centrifugation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/04—Investigating sedimentation of particle suspensions
- G01N15/042—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/01—Arrangements or apparatus for facilitating the optical investigation
- G01N21/03—Cuvette constructions
- G01N21/07—Centrifugal type cuvettes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/491—Blood by separating the blood components
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N35/00069—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides whereby the sample substrate is of the bio-disk type, i.e. having the format of an optical disk
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0681—Filter
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0803—Disc shape
- B01L2300/0806—Standardised forms, e.g. compact disc [CD] format
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/16—Surface properties and coatings
- B01L2300/168—Specific optical properties, e.g. reflective coatings
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/02—Investigating particle size or size distribution
- G01N15/0272—Investigating particle size or size distribution with screening; with classification by filtering
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N2015/0092—Monitoring flocculation or agglomeration
-
- G01N2015/012—
-
- G01N2015/016—
-
- G01N2015/018—
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume, or surface-area of porous materials
- G01N15/04—Investigating sedimentation of particle suspensions
- G01N15/042—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates
- G01N2015/045—Investigating sedimentation of particle suspensions by centrifuging and investigating centrifugates by optical analysis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00178—Special arrangements of analysers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00465—Separating and mixing arrangements
- G01N2035/00495—Centrifuges
- G01N2035/00504—Centrifuges combined with carousels
Abstract
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP01987031A EP1410045A2 (en) | 2000-11-22 | 2001-11-20 | Apparatus and methods for separating agglutinants and disperse particles |
AU2002239289A AU2002239289A1 (en) | 2000-11-22 | 2001-11-20 | Apparatus and methods for separating agglutinants and disperse particles |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25272500P | 2000-11-22 | 2000-11-22 | |
US60/252,725 | 2000-11-22 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2002042780A2 WO2002042780A2 (en) | 2002-05-30 |
WO2002042780A3 true WO2002042780A3 (en) | 2003-08-28 |
WO2002042780A9 WO2002042780A9 (en) | 2004-03-04 |
Family
ID=22957264
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2001/043373 WO2002042780A2 (en) | 2000-11-22 | 2001-11-20 | Apparatus and methods for separating agglutinants and disperse particles |
Country Status (4)
Country | Link |
---|---|
US (1) | US20020196435A1 (en) |
EP (1) | EP1410045A2 (en) |
AU (1) | AU2002239289A1 (en) |
WO (1) | WO2002042780A2 (en) |
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US7026131B2 (en) * | 2000-11-17 | 2006-04-11 | Nagaoka & Co., Ltd. | Methods and apparatus for blood typing with optical bio-discs |
WO2002043866A2 (en) * | 2000-12-01 | 2002-06-06 | Burstein Technologies, Inc. | Apparatus and methods for separating components of particulate suspension |
US7091034B2 (en) * | 2000-12-15 | 2006-08-15 | Burstein Technologies, Inc. | Detection system for disk-based laboratory and improved optical bio-disc including same |
WO2002051537A2 (en) * | 2000-12-22 | 2002-07-04 | Burstein Technologies, Inc. | Optical bio-discs and methods relating thereto |
US20030077598A1 (en) * | 2001-01-04 | 2003-04-24 | Phan Brigitte Chau | Dual bead assays including covalent linkages for improved specificity and related optical analysis discs |
DE10111457B4 (en) * | 2001-03-09 | 2006-12-14 | Siemens Ag | diagnostic device |
WO2003087827A2 (en) | 2001-04-11 | 2003-10-23 | Burstein Technologies, Inc. | Multi-parameter assays including analysis discs and methods relating thereto |
WO2003027723A2 (en) * | 2001-07-24 | 2003-04-03 | Burstein Technologies, Inc. | Method and apparatus for bonded fluidic circuit for optical bio-disc |
US20030129665A1 (en) * | 2001-08-30 | 2003-07-10 | Selvan Gowri Pyapali | Methods for qualitative and quantitative analysis of cells and related optical bio-disc systems |
WO2003043403A2 (en) * | 2001-11-19 | 2003-05-30 | Burstein Technologies, Inc. | Methods and apparatus for blood typing with optical bio-discs |
AU2002352735A1 (en) * | 2001-11-20 | 2003-06-10 | Burstein Technologies, Inc. | Optical bio-discs and microfluidic devices for analysis of cells |
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US7125711B2 (en) * | 2002-12-19 | 2006-10-24 | Bayer Healthcare Llc | Method and apparatus for splitting of specimens into multiple channels of a microfluidic device |
US20040166551A1 (en) * | 2003-02-24 | 2004-08-26 | John Moulds | Detection of agglutination of assays |
EP1599730A2 (en) * | 2003-03-03 | 2005-11-30 | Kouyama, Yoshihisa | Methods and apparatus for use in detection and quantitation of various cell types and use of optical bio-disc for performing same |
US20050037484A1 (en) * | 2003-04-23 | 2005-02-17 | Norbert Staimer | Optical bio-discs including spiral fluidic circuits for performing assays |
US7390464B2 (en) * | 2003-06-19 | 2008-06-24 | Burstein Technologies, Inc. | Fluidic circuits for sample preparation including bio-discs and methods relating thereto |
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US7327443B2 (en) * | 2004-07-01 | 2008-02-05 | Gambro Bct, Inc | Stroboscopic LED light source for blood processing apparatus |
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US20070054405A1 (en) * | 2003-10-23 | 2007-03-08 | Ortho-Clinical Diagnostics, Inc. | Patient sample classification based upon low angle light scattering |
DE10352535A1 (en) * | 2003-11-07 | 2005-06-16 | Steag Microparts Gmbh | A microstructured separator and method of separating liquid components from a liquid containing particles |
AU2006236410B2 (en) * | 2005-04-19 | 2012-11-01 | President And Fellows Of Harvard College | Fluidic structures including meandering and wide channels |
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US8241196B2 (en) * | 2008-12-22 | 2012-08-14 | Terumo Bct, Inc. | Blood processing apparatus with digitally controlled linear voltage regulator for optical pulses |
JP5810267B2 (en) * | 2010-05-12 | 2015-11-11 | パナソニックIpマネジメント株式会社 | Plasmon sensor, method of use and manufacturing method thereof |
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CN105164538B (en) * | 2013-05-08 | 2017-10-31 | 索尼公司 | Flow path device, analytical equipment and fluid means |
GB2534182A (en) * | 2015-01-15 | 2016-07-20 | Univ Dublin City | Microfluidic device |
WO2016161337A1 (en) * | 2015-04-03 | 2016-10-06 | Captl Llc | Particle detection using reflective surface |
US10613096B2 (en) | 2015-08-28 | 2020-04-07 | Captl Llc | Multi-spectral microparticle-fluorescence photon cytometry |
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WO1993022053A1 (en) * | 1992-05-01 | 1993-11-11 | Trustees Of The University Of Pennsylvania | Microfabricated detection structures |
US5892577A (en) * | 1994-09-21 | 1999-04-06 | The University Court Of The University Of Glasgow | Apparatus and method for carrying out analysis of samples |
WO2000005582A2 (en) * | 1998-07-21 | 2000-02-03 | Burstein Laboratories, Inc. | Optical disc-based assay devices and methods |
US6030581A (en) * | 1997-02-28 | 2000-02-29 | Burstein Laboratories | Laboratory in a disk |
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-
2001
- 2001-11-20 AU AU2002239289A patent/AU2002239289A1/en not_active Abandoned
- 2001-11-20 WO PCT/US2001/043373 patent/WO2002042780A2/en not_active Application Discontinuation
- 2001-11-20 EP EP01987031A patent/EP1410045A2/en not_active Withdrawn
- 2001-11-20 US US09/989,684 patent/US20020196435A1/en not_active Abandoned
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993022053A1 (en) * | 1992-05-01 | 1993-11-11 | Trustees Of The University Of Pennsylvania | Microfabricated detection structures |
US5892577A (en) * | 1994-09-21 | 1999-04-06 | The University Court Of The University Of Glasgow | Apparatus and method for carrying out analysis of samples |
US6030581A (en) * | 1997-02-28 | 2000-02-29 | Burstein Laboratories | Laboratory in a disk |
WO2000005582A2 (en) * | 1998-07-21 | 2000-02-03 | Burstein Laboratories, Inc. | Optical disc-based assay devices and methods |
Also Published As
Publication number | Publication date |
---|---|
AU2002239289A1 (en) | 2002-06-03 |
US20020196435A1 (en) | 2002-12-26 |
WO2002042780A2 (en) | 2002-05-30 |
WO2002042780A9 (en) | 2004-03-04 |
EP1410045A2 (en) | 2004-04-21 |
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