WO2002048361A3 - Novel secreted proteins and their uses - Google Patents

Novel secreted proteins and their uses Download PDF

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Publication number
WO2002048361A3
WO2002048361A3 PCT/US2001/043174 US0143174W WO0248361A3 WO 2002048361 A3 WO2002048361 A3 WO 2002048361A3 US 0143174 W US0143174 W US 0143174W WO 0248361 A3 WO0248361 A3 WO 0248361A3
Authority
WO
WIPO (PCT)
Prior art keywords
secreted proteins
novel secreted
useful
novel
proteins
Prior art date
Application number
PCT/US2001/043174
Other languages
French (fr)
Other versions
WO2002048361A2 (en
Inventor
Margret Barbara Basinski
Radmila Micanovic
Bradley Jay Mills
Patanjali Raghavac Sankhavaram
Eric Wen Su
Sheng-Hung Rainbow Tschang
Gabor Varga
He Wang
Original Assignee
Lilly Co Eli
Margret Barbara Basinski
Radmila Micanovic
Bradley Jay Mills
Patanjali Raghavac Sankhavaram
Eric Wen Su
Sheng-Hung Rainbow Tschang
Gabor Varga
He Wang
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli, Margret Barbara Basinski, Radmila Micanovic, Bradley Jay Mills, Patanjali Raghavac Sankhavaram, Eric Wen Su, Sheng-Hung Rainbow Tschang, Gabor Varga, He Wang filed Critical Lilly Co Eli
Priority to EP01985964A priority Critical patent/EP1399474A2/en
Priority to AU2002236440A priority patent/AU2002236440A1/en
Publication of WO2002048361A2 publication Critical patent/WO2002048361A2/en
Publication of WO2002048361A3 publication Critical patent/WO2002048361A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Abstract

The present invention provides nucleic acid sequences encoding novel human proteins. These novel nucleic acids are useful for constructing the claimed DNA vectors and host cells of the invention and for preparing the claimed recombinant proteins and antibodies that are useful in the claimed methods and medical uses.
PCT/US2001/043174 2000-12-15 2001-12-04 Novel secreted proteins and their uses WO2002048361A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP01985964A EP1399474A2 (en) 2000-12-15 2001-12-04 Secreted proteins and their use
AU2002236440A AU2002236440A1 (en) 2000-12-15 2001-12-04 Novel secreted proteins and their uses

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25585000P 2000-12-15 2000-12-15
US60/255,850 2000-12-15

Publications (2)

Publication Number Publication Date
WO2002048361A2 WO2002048361A2 (en) 2002-06-20
WO2002048361A3 true WO2002048361A3 (en) 2003-12-24

Family

ID=22970116

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/043174 WO2002048361A2 (en) 2000-12-15 2001-12-04 Novel secreted proteins and their uses

Country Status (3)

Country Link
EP (1) EP1399474A2 (en)
AU (1) AU2002236440A1 (en)
WO (1) WO2002048361A2 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8008332B2 (en) 2006-05-31 2011-08-30 Takeda San Diego, Inc. Substituted indazoles as glucokinase activators
US8034822B2 (en) 2006-03-08 2011-10-11 Takeda San Diego, Inc. Glucokinase activators
US8124617B2 (en) 2005-09-01 2012-02-28 Takeda San Diego, Inc. Imidazopyridine compounds
US8163779B2 (en) 2006-12-20 2012-04-24 Takeda San Diego, Inc. Glucokinase activators
US8173645B2 (en) 2007-03-21 2012-05-08 Takeda San Diego, Inc. Glucokinase activators

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001239765A1 (en) * 2000-02-14 2001-08-27 Smith Kline Beecham Corporation Novel compounds

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997007198A2 (en) * 1995-08-11 1997-02-27 Genetics Institute, Inc. Dna sequences and secreted proteins encoded thereby

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002048368A2 (en) * 2000-12-14 2002-06-20 Incyte Genomics, Inc. Proteins associated with cell growth, differentiation, and death

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997007198A2 (en) * 1995-08-11 1997-02-27 Genetics Institute, Inc. Dna sequences and secreted proteins encoded thereby

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL [online] EBI, Hinxton UK; 21 June 2000 (2000-06-21), "Homo sapiens chromosome 19 clone CTD-2527I21, WORKING DRAFT SEQUENCE, 39 unordered pieces.", XP002215015, Database accession no. AC020907 *
DATABASE EMBL [online] EBI, Hinxton UK; 31 October 2001 (2001-10-31), "603176686F1 NIH_MGC_121 Homo sapiens cDNA clone IMAGE:5240997 5', mRNA sequence.", XP002214928, Database accession no. BI918512 *
DATABASE EMBL [online] EBI, Hinxton, UK; 1 September 1999 (1999-09-01), "wt51e04.x1 NCI_CGAP_Pan1 Homo sapiens cDNA clone IMAGE:2511006 3', mRNA sequence.", XP002215556, Database accession no. AI983848 *
KLEIN R D ET AL: "SELECTION FOR GENES ENCODING SECRETED PROTEINS AND RECEPTORS", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 93, no. 14, 9 July 1996 (1996-07-09), pages 7108 - 7113, XP002061411, ISSN: 0027-8424 *
SCHEEL HARTMUT ET AL: "A common protein interaction domain links two recently identified epilepsy genes.", HUMAN MOLECULAR GENETICS, vol. 11, no. 15, 2002, 15 July, 2002, pages 1757 - 1762, XP002214927, ISSN: 0964-6906 *
See also references of EP1399474A2 *
SOMERVILLE ROBERT P T ET AL: "Identification of the promoter, genomic structure, and mouse ortholog of LGI1.", MAMMALIAN GENOME, vol. 11, no. 8, August 2000 (2000-08-01), pages 622 - 627, XP002214926, ISSN: 0938-8990 *
YOKOYAMA-KOBAYASHI M ET AL: "A signal sequence detection system using secreted protease activity as an indicator", GENE, ELSEVIER BIOMEDICAL PRESS. AMSTERDAM, NL, vol. 163, no. 2, 3 October 1995 (1995-10-03), pages 193 - 196, XP004041983, ISSN: 0378-1119 *

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8124617B2 (en) 2005-09-01 2012-02-28 Takeda San Diego, Inc. Imidazopyridine compounds
US8034822B2 (en) 2006-03-08 2011-10-11 Takeda San Diego, Inc. Glucokinase activators
US8008332B2 (en) 2006-05-31 2011-08-30 Takeda San Diego, Inc. Substituted indazoles as glucokinase activators
US8394843B2 (en) 2006-05-31 2013-03-12 Takeda California, Inc. Substituted isoindoles as glucokinase activators
US8163779B2 (en) 2006-12-20 2012-04-24 Takeda San Diego, Inc. Glucokinase activators
US8173645B2 (en) 2007-03-21 2012-05-08 Takeda San Diego, Inc. Glucokinase activators

Also Published As

Publication number Publication date
WO2002048361A2 (en) 2002-06-20
AU2002236440A1 (en) 2002-06-24
EP1399474A2 (en) 2004-03-24

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