WO2002056256A3 - A system and method for finding regions of interest for microscopic digital montage imaging - Google Patents

A system and method for finding regions of interest for microscopic digital montage imaging Download PDF

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Publication number
WO2002056256A3
WO2002056256A3 PCT/US2002/000458 US0200458W WO02056256A3 WO 2002056256 A3 WO2002056256 A3 WO 2002056256A3 US 0200458 W US0200458 W US 0200458W WO 02056256 A3 WO02056256 A3 WO 02056256A3
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WO
WIPO (PCT)
Prior art keywords
tissue
component
image
slide
finding
Prior art date
Application number
PCT/US2002/000458
Other languages
French (fr)
Other versions
WO2002056256A2 (en
Inventor
Arthur W Wetzel
John R Ii Gilbertson
Jeffrey A Beckstead
Patricia A Feineigle
Christopher R Hauser
Frank A Palmieri Jr
Original Assignee
Interscope Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Interscope Technologies Inc filed Critical Interscope Technologies Inc
Priority to AU2002237779A priority Critical patent/AU2002237779A1/en
Publication of WO2002056256A2 publication Critical patent/WO2002056256A2/en
Publication of WO2002056256A3 publication Critical patent/WO2002056256A3/en

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Classifications

    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06VIMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00Scenes; Scene-specific elements
    • G06V20/60Type of objects
    • G06V20/69Microscopic objects, e.g. biological cells or cellular parts
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06VIMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V10/00Arrangements for image or video recognition or understanding
    • G06V10/20Image preprocessing
    • G06V10/25Determination of region of interest [ROI] or a volume of interest [VOI]
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06VIMAGE OR VIDEO RECOGNITION OR UNDERSTANDING
    • G06V20/00Scenes; Scene-specific elements
    • G06V20/60Type of objects
    • G06V20/69Microscopic objects, e.g. biological cells or cellular parts
    • G06V20/693Acquisition

Abstract

A system for processing a thumbnail image from a microscope slide to determine tissue locations on the slide. The system comprises an image cropping component, a tissue finding component, and a scan control component. The image cropping component crops the thumbnail image and removes portions of the image that fall outside of determined slide boundaries. The cropped image from the image cropping component is inputted into the tissue finding component. The tissue finding component identifies tissue regions by applying a sequence of filters that incorporate knowledge of typical appearance and location of tissue and non-tissue slide regions. The tissue finding component outputs a tiling matrix whose values indicate which tiles should be imaged. The scan control component interprets the tiling matrix and transposes positions of the tiling matrix into actual stage coordinate for a microscopic imaging.
PCT/US2002/000458 2001-01-11 2002-01-08 A system and method for finding regions of interest for microscopic digital montage imaging WO2002056256A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002237779A AU2002237779A1 (en) 2001-01-11 2002-01-08 A system and method for finding regions of interest for microscopic digital montage imaging

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/758,037 US6993169B2 (en) 2001-01-11 2001-01-11 System and method for finding regions of interest for microscopic digital montage imaging
US09/758,037 2001-01-11

Publications (2)

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WO2002056256A2 WO2002056256A2 (en) 2002-07-18
WO2002056256A3 true WO2002056256A3 (en) 2003-02-13

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PCT/US2002/000458 WO2002056256A2 (en) 2001-01-11 2002-01-08 A system and method for finding regions of interest for microscopic digital montage imaging

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US (5) US6993169B2 (en)
AU (1) AU2002237779A1 (en)
WO (1) WO2002056256A2 (en)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6272235B1 (en) * 1997-03-03 2001-08-07 Bacus Research Laboratories, Inc. Method and apparatus for creating a virtual microscope slide
US6606413B1 (en) 1998-06-01 2003-08-12 Trestle Acquisition Corp. Compression packaged image transmission for telemicroscopy
US7464877B2 (en) * 2003-11-13 2008-12-16 Metrologic Instruments, Inc. Digital imaging-based bar code symbol reading system employing image cropping pattern generator and automatic cropped image processor
US7155049B2 (en) * 2001-01-11 2006-12-26 Trestle Acquisition Corp. System for creating microscopic digital montage images
US6993169B2 (en) * 2001-01-11 2006-01-31 Trestle Corporation System and method for finding regions of interest for microscopic digital montage imaging
AU2002254276A1 (en) 2001-03-19 2002-10-03 Peter H. Bartels Miniaturized microscope array digital slide scanner
WO2003025838A1 (en) 2001-09-14 2003-03-27 The Arizona Board Of Regents On Behalf Of The University Of Arizona Inter-objective baffle system
US20050207630A1 (en) * 2002-02-15 2005-09-22 The Regents Of The University Of Michigan Technology Management Office Lung nodule detection and classification
JP2007510199A (en) * 2003-10-08 2007-04-19 ライフスパン バイオサイエンス,インク. Automated microscope slide tissue sample mapping and image acquisition
KR100670003B1 (en) * 2004-12-28 2007-01-19 삼성전자주식회사 The apparatus for detecting the homogeneous region in the image using the adaptive threshold value
DE102005018855B4 (en) * 2005-04-22 2010-01-28 Theta System Elektronik Gmbh Apparatus for inspecting printed products
US8921102B2 (en) 2005-07-29 2014-12-30 Gpb Scientific, Llc Devices and methods for enrichment and alteration of circulating tumor cells and other particles
US7627153B2 (en) * 2005-08-04 2009-12-01 Carl Zeiss Microimaging Gmbh Repositioning inaccuracies in an automated imaging system
JP4330168B2 (en) 2005-09-06 2009-09-16 キヤノン株式会社 Mold, imprint method, and chip manufacturing method
US7929738B2 (en) * 2005-10-11 2011-04-19 Olympus Corporation Microscope apparatus and microscope system
CA2625775A1 (en) 2005-10-14 2007-04-19 Applied Research Associates Nz Limited A method of monitoring a surface feature and apparatus therefor
HUP0600177A2 (en) * 2006-03-03 2009-03-02 3D Histech Kft Equipment for and method of digitizing slides by automated digital image recording system
US8780139B2 (en) 2006-03-27 2014-07-15 Adobe Systems Incorporated Resolution monitoring when using visual manipulation tools
JP4890096B2 (en) * 2006-05-19 2012-03-07 浜松ホトニクス株式会社 Image acquisition apparatus, image acquisition method, and image acquisition program
US8137912B2 (en) 2006-06-14 2012-03-20 The General Hospital Corporation Methods for the diagnosis of fetal abnormalities
US8372584B2 (en) 2006-06-14 2013-02-12 The General Hospital Corporation Rare cell analysis using sample splitting and DNA tags
US20080050739A1 (en) 2006-06-14 2008-02-28 Roland Stoughton Diagnosis of fetal abnormalities using polymorphisms including short tandem repeats
EP2029779A4 (en) 2006-06-14 2010-01-20 Living Microsystems Inc Use of highly parallel snp genotyping for fetal diagnosis
GB2474611B (en) * 2006-09-08 2011-09-07 Thermo Shandon Ltd Image based detector for slides or baskets for use in a slide processing apparatus
US20100034425A1 (en) * 2006-10-20 2010-02-11 Thomson Licensing Method, apparatus and system for generating regions of interest in video content
WO2008085907A2 (en) * 2007-01-05 2008-07-17 Carl Zeiss Microimaging Ais, Inc. System and method for analyzing tissue slides for observable pathologies
US8126267B2 (en) * 2007-02-05 2012-02-28 Albany Medical College Methods and apparatuses for analyzing digital images to automatically select regions of interest thereof
US8098956B2 (en) * 2007-03-23 2012-01-17 Vantana Medical Systems, Inc. Digital microscope slide scanning system and methods
DK2156370T3 (en) 2007-05-14 2012-01-23 Historx Inc Compartment separation by pixel characterization using image data clustering
EP2162728B1 (en) * 2007-06-15 2016-07-27 Novartis AG Microscope system and method for obtaining standardized sample data
DE102007033793A1 (en) * 2007-07-19 2009-01-22 Carl Zeiss Imaging Solutions Gmbh Method and apparatus for microscopically examining a sample, computer program and computer program product
CA2604317C (en) 2007-08-06 2017-02-28 Historx, Inc. Methods and system for validating sample images for quantitative immunoassays
CA2596204C (en) * 2007-08-07 2019-02-26 Historx, Inc. Method and system for determining an optimal dilution of a reagent
WO2009029810A1 (en) * 2007-08-31 2009-03-05 Historx, Inc. Automatic exposure time selection for imaging tissue
US20090118600A1 (en) * 2007-11-02 2009-05-07 Ortiz Joseph L Method and apparatus for skin documentation and analysis
US20090136098A1 (en) * 2007-11-27 2009-05-28 Honeywell International, Inc. Context sensitive pacing for effective rapid serial visual presentation
US8059136B2 (en) * 2007-12-11 2011-11-15 Honeywell International Inc. Hierarchichal rapid serial visual presentation for robust target identification
US8170698B1 (en) * 2008-02-20 2012-05-01 Mark David Gusack Virtual robotic controller system with special application to robotic microscopy structure and methodology
NL2001464C2 (en) * 2008-04-10 2009-10-13 Amc Amsterdam Method for forming an image of an object.
EP2335221B8 (en) * 2008-09-16 2016-05-25 Novartis AG Reproducible quantification of biomarker expression
EP2334812B1 (en) 2008-09-20 2016-12-21 The Board of Trustees of The Leland Stanford Junior University Noninvasive diagnosis of fetal aneuploidy by sequencing
CA2755164C (en) 2009-03-11 2014-02-25 Sensovation Ag Autofocus method and autofocus device
JP5387328B2 (en) * 2009-08-31 2014-01-15 ソニー株式会社 Fluorescence image acquisition apparatus, fluorescence image acquisition method, and fluorescence image acquisition program
WO2011049608A2 (en) 2009-10-19 2011-04-28 Bioimagene, Inc. Imaging system and techniques
US10139613B2 (en) 2010-08-20 2018-11-27 Sakura Finetek U.S.A., Inc. Digital microscope and method of sensing an image of a tissue sample
DE102011075809A1 (en) * 2011-05-13 2012-11-15 Carl Zeiss Microimaging Gmbh Method and device for defining a z-range in a sample, in which a z-stack of the sample is to be picked up by means of a microscope
US9179844B2 (en) 2011-11-28 2015-11-10 Aranz Healthcare Limited Handheld skin measuring or monitoring device
FR2983963B1 (en) * 2011-12-12 2016-05-06 Tribvn METHOD FOR ANALYZING A BIOLOGICAL SAMPLE, AND DEVICE USING THE SAME
CN103185542A (en) * 2011-12-28 2013-07-03 鸿富锦精密工业(深圳)有限公司 Inclined plane boundary scanning system and inclined plane boundary scanning method
CA2867508C (en) * 2012-03-30 2021-05-18 Clarient Diagnostic Services, Inc. Immunofluorescence and fluorescent-based nucleic acid analysis on a single sample
WO2014006964A1 (en) * 2012-07-04 2014-01-09 ソニー株式会社 Information processing device, information processing method, program, and microscope system
EP2693396A1 (en) * 2012-07-30 2014-02-05 Nokia Corporation Method, apparatus and computer program product for processing of multimedia content
JP2016522880A (en) * 2013-03-15 2016-08-04 リチャード・ハリー・ターナー System and method for in vitro detection of particles and soluble chemicals in body fluids
DE102013103971A1 (en) 2013-04-19 2014-11-06 Sensovation Ag Method for generating an overall picture of an object composed of several partial images
GB2542765A (en) * 2015-09-23 2017-04-05 Pathxl Ltd Method and apparatus for tissue recognition
GB201308664D0 (en) * 2013-05-14 2013-06-26 Pathxl Ltd Method and apparatus
US9842391B2 (en) 2013-05-14 2017-12-12 Pathxl Limited Method and apparatus for processing an image of a tissue sample
US10007102B2 (en) 2013-12-23 2018-06-26 Sakura Finetek U.S.A., Inc. Microscope with slide clamping assembly
US20170085790A1 (en) * 2015-09-23 2017-03-23 Microsoft Technology Licensing, Llc High-resolution imaging of regions of interest
US10013527B2 (en) 2016-05-02 2018-07-03 Aranz Healthcare Limited Automatically assessing an anatomical surface feature and securely managing information related to the same
US10453195B2 (en) * 2016-08-19 2019-10-22 Optrascan, Inc. Method of detecting tissue area of interest in digital pathology imaging by executing computer-executable instructions stored on a non-transitory computer-readable medium
US11116407B2 (en) 2016-11-17 2021-09-14 Aranz Healthcare Limited Anatomical surface assessment methods, devices and systems
US11280803B2 (en) 2016-11-22 2022-03-22 Sakura Finetek U.S.A., Inc. Slide management system
EP4183328A1 (en) 2017-04-04 2023-05-24 Aranz Healthcare Limited Anatomical surface assessment methods, devices and systems
US9870615B2 (en) 2017-07-19 2018-01-16 Schwalb Consulting, LLC Morphology identification in tissue samples based on comparison to named feature vectors
US10846854B2 (en) * 2017-10-13 2020-11-24 Shenzhen Keya Medical Technology Corporation Systems and methods for detecting cancer metastasis using a neural network
GB2614223B (en) * 2019-01-22 2023-10-11 Emulate Inc High-content imaging of microfluidic devices
CN113658209B (en) * 2021-08-12 2023-06-16 山东省计算中心(国家超级计算济南中心) Morphology-based excellent discriminating method for mounting position of slice tissue

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992013308A1 (en) * 1991-01-29 1992-08-06 Neuromedical Systems, Inc. Morphological classification system and method
US5933519A (en) * 1994-09-20 1999-08-03 Neo Path, Inc. Cytological slide scoring apparatus
US6151405A (en) * 1996-11-27 2000-11-21 Chromavision Medical Systems, Inc. System and method for cellular specimen grading

Family Cites Families (80)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3999047A (en) * 1972-09-05 1976-12-21 Green James E Method and apparatus utilizing color algebra for analyzing scene regions
GB1404628A (en) 1972-12-07 1975-09-03 Coulter Electronics Method and apparatus for analyzing microscopic particles
US4150360A (en) * 1975-05-29 1979-04-17 Grumman Aerospace Corporation Method and apparatus for classifying biological cells
US4199748A (en) * 1976-11-01 1980-04-22 Rush-Presbyterian-St. Luke's Medical Center Automated method and apparatus for classification of cells with application to the diagnosis of anemia
US4136950A (en) * 1976-11-08 1979-01-30 Labrum Engineering, Inc. Microscope system for observing moving particles
US4213036A (en) * 1977-12-27 1980-07-15 Grumman Aerospace Corporation Method for classifying biological cells
DE2903855A1 (en) * 1979-02-01 1980-08-14 Bloss Werner H Prof Dr Ing METHOD FOR AUTOMATICALLY MARKING CELLS AND DETERMINING THE CHARACTERISTICS OF CELLS FROM CYTOLOGICAL MEASUREMENT DEVICES
US4523102A (en) * 1980-03-17 1985-06-11 Matsushita Electric Industrial Co., Ltd. Solid-state color-image sensor and process for fabricating the same
US4742558A (en) * 1984-02-14 1988-05-03 Nippon Telegraph & Telephone Public Corporation Image information retrieval/display apparatus
US4779151A (en) * 1985-04-08 1988-10-18 Odetics, Inc. Robotic tape cassette handling system with rotary loading and unloading mechanism
US5216596A (en) * 1987-04-30 1993-06-01 Corabi International Telemetrics, Inc. Telepathology diagnostic network
JP2686274B2 (en) * 1988-03-24 1997-12-08 東亜医用電子株式会社 Cell image processing method and apparatus
US4965725B1 (en) * 1988-04-08 1996-05-07 Neuromedical Systems Inc Neural network based automated cytological specimen classification system and method
US5740270A (en) * 1988-04-08 1998-04-14 Neuromedical Systems, Inc. Automated cytological specimen classification system and method
US5544650A (en) * 1988-04-08 1996-08-13 Neuromedical Systems, Inc. Automated specimen classification system and method
JP2813348B2 (en) * 1988-04-22 1998-10-22 東亜医用電子株式会社 Cell image extraction storage processing device and method
US5163095A (en) * 1988-04-22 1992-11-10 Toa Medical Electronics Co., Ltd. Processor for extracting and memorizing cell images, and method of practicing same
US5143193A (en) * 1988-06-30 1992-09-01 Ronald Geraci Automated library article terminal
US5252487A (en) * 1989-05-19 1993-10-12 Cell Analysis Systems, Inc. Method and apparatus for determining the amount of oncogene protein product in a cell sample
US5073857A (en) * 1989-06-01 1991-12-17 Accuron Corporation Method and apparatus for cell analysis
DE3922358A1 (en) 1989-07-07 1991-01-10 Heinz Walz Mess Und Regeltechn Detecting contaminants in aqueous liquids using microscope - using micro-camera pulsed flash and light chopper to produce banded motion tracks
US5268966A (en) * 1989-08-10 1993-12-07 International Remote Imaging Systems, Inc. Method of differentiating particles based upon a dynamically changing threshold
US5107422A (en) * 1989-10-02 1992-04-21 Kamentsky Louis A Method and apparatus for measuring multiple optical properties of biological specimens
US5072382A (en) * 1989-10-02 1991-12-10 Kamentsky Louis A Methods and apparatus for measuring multiple optical properties of biological specimens
US5149972A (en) * 1990-01-18 1992-09-22 University Of Massachusetts Medical Center Two excitation wavelength video imaging microscope
US5313532A (en) * 1990-01-23 1994-05-17 Massachusetts Institute Of Technology Recognition of patterns in images
US5123056A (en) * 1990-02-02 1992-06-16 Siemens Medical Systems, Inc. Whole-leg x-ray image processing and display techniques
US5199840A (en) * 1990-08-01 1993-04-06 John Castaldi Automated storage and retrieval system
US6196226B1 (en) * 1990-08-10 2001-03-06 University Of Washington Methods and apparatus for optically imaging neuronal tissue and activity
ATE178728T1 (en) * 1990-11-07 1999-04-15 Neuromedical Systems Inc EXAMINATION CONTROL PROCEDURES FOR IMAGES SHOWN ON A DISPLAY
US5784162A (en) * 1993-08-18 1998-07-21 Applied Spectral Imaging Ltd. Spectral bio-imaging methods for biological research, medical diagnostics and therapy
US5218645A (en) * 1991-03-29 1993-06-08 Cell Analysis Systems, Inc. Method and apparatus for separating cell objects for analysis
US5216500A (en) * 1991-07-15 1993-06-01 Rj Lee Group, Inc. Simultaneously recording of video image and microscope stage position data
US5260871A (en) * 1991-07-31 1993-11-09 Mayo Foundation For Medical Education And Research Method and apparatus for diagnosis of breast tumors
US5428690A (en) * 1991-09-23 1995-06-27 Becton Dickinson And Company Method and apparatus for automated assay of biological specimens
CA2077781A1 (en) * 1991-09-23 1993-03-24 James W. Bacus Method and apparatus for automated assay of biological specimens
EP0622001A1 (en) 1992-01-14 1994-11-02 SUSSMAN, Michael Image input device having optical deflection elements for capturing multiple sub-images
US5912699A (en) * 1992-02-18 1999-06-15 Neopath, Inc. Method and apparatus for rapid capture of focused microscopic images
US5298963A (en) 1992-02-26 1994-03-29 Mitsui Mining & Smelting Co., Ltd. Apparatus for inspecting the surface of materials
GB2267382A (en) * 1992-05-23 1993-12-01 Ibm Robotic manipulator
GB2269473A (en) * 1992-08-08 1994-02-09 Ibm A robotic cassette transfer apparatus
EP0610916A3 (en) * 1993-02-09 1994-10-12 Cedars Sinai Medical Center Method and apparatus for providing preferentially segmented digital images.
US5381224A (en) * 1993-08-30 1995-01-10 A. E. Dixon Scanning laser imaging system
US5625765A (en) * 1993-09-03 1997-04-29 Criticom Corp. Vision systems including devices and methods for combining images for extended magnification schemes
US5509191A (en) * 1994-01-26 1996-04-23 Best; Norman D. Apparatus for assembling and processing small parts using a robot
US5417215A (en) * 1994-02-04 1995-05-23 Long Island Jewish Medical Center Method of tissue characterization by ultrasound
US5505946A (en) * 1994-04-01 1996-04-09 Trustees Of Univ Of Pa Bowman-birk inhibitor concentrate compositions and methods for the treatment of pre-malignant tissue
US5499097A (en) * 1994-09-19 1996-03-12 Neopath, Inc. Method and apparatus for checking automated optical system performance repeatability
US5647025A (en) * 1994-09-20 1997-07-08 Neopath, Inc. Automatic focusing of biomedical specimens apparatus
US5638459A (en) * 1994-09-20 1997-06-10 Neopath, Inc. Method and apparatus for detecting a microscope slide coverslip
US5848177A (en) * 1994-12-29 1998-12-08 Board Of Trustees Operating Michigan State University Method and system for detection of biological materials using fractal dimensions
JPH08287218A (en) * 1995-04-10 1996-11-01 Sharp Corp Image composing device
WO1997004347A1 (en) 1995-07-19 1997-02-06 Morphometrix Technologies Inc. Automated scanning of microscope slides
US6091842A (en) * 1996-10-25 2000-07-18 Accumed International, Inc. Cytological specimen analysis system with slide mapping and generation of viewing path information
EP1300713A3 (en) * 1995-11-30 2004-11-03 Chromavision Medical Systems, Inc. Method and apparatus for automated image analysis of biological specimens
US5768125A (en) * 1995-12-08 1998-06-16 Asm International N.V. Apparatus for transferring a substantially circular article
US5835620A (en) * 1995-12-19 1998-11-10 Neuromedical Systems, Inc. Boundary mapping system and method
US5700125A (en) * 1996-03-27 1997-12-23 Storage Technology Corporation Gravity feed pass-thru port for automated cartridge library
WO1998002843A1 (en) * 1996-07-12 1998-01-22 Erim International, Inc. Mosaic construction, processing, and review of very large electronic micrograph composites
US6272235B1 (en) * 1997-03-03 2001-08-07 Bacus Research Laboratories, Inc. Method and apparatus for creating a virtual microscope slide
US6031930A (en) * 1996-08-23 2000-02-29 Bacus Research Laboratories, Inc. Method and apparatus for testing a progression of neoplasia including cancer chemoprevention testing
US6081612A (en) * 1997-02-28 2000-06-27 Electro Optical Sciences Inc. Systems and methods for the multispectral imaging and characterization of skin tissue
US6172349B1 (en) * 1997-03-31 2001-01-09 Kla-Tencor Corporation Autofocusing apparatus and method for high resolution microscope system
US5878152A (en) * 1997-05-21 1999-03-02 Cognex Corporation Depth from focal gradient analysis using object texture removal by albedo normalization
JP3815759B2 (en) 1997-09-22 2006-08-30 キヤノン株式会社 Detection method, exposure apparatus, and device manufacturing method
US6014451A (en) * 1997-10-17 2000-01-11 Pioneer Hi-Bred International, Inc. Remote imaging system for plant diagnosis
AU1539699A (en) * 1997-11-24 1999-06-15 Johnson T. Wong Methods for treatment of hiv or other infections using a t cell or viral activator and anti-retroviral combination therapy
DE19824460A1 (en) * 1998-05-30 1999-12-02 Zeiss Carl Jena Gmbh Arrangement and method for the microscopic generation of object images
US6577342B1 (en) * 1998-09-25 2003-06-10 Intel Corporation Image sensor with microlens material structure
US6429036B1 (en) * 1999-01-14 2002-08-06 Micron Technology, Inc. Backside illumination of CMOS image sensor
DE19923821A1 (en) 1999-05-19 2000-11-23 Zeiss Carl Jena Gmbh Method and device for recording the position of a surface to be scanned with a laser scanner includes a microscope beam input directed through a microscope lens onto a lens with a biochip to pick up fluorescent samples.
WO2001037192A1 (en) 1999-11-18 2001-05-25 Ikonisys, Inc. Method and apparatus for computer controlled cell based diagnosis
US6304684B1 (en) 2000-02-15 2001-10-16 Cyberecord, Inc. Information processing system and method of using same
US6711283B1 (en) * 2000-05-03 2004-03-23 Aperio Technologies, Inc. Fully automatic rapid microscope slide scanner
TW475334B (en) * 2000-07-14 2002-02-01 Light Opto Electronics Co Ltd High light-sensing efficiency image sensor apparatus and method of making the same
US6466690C1 (en) * 2000-12-19 2008-11-18 Bacus Res Lab Inc Method and apparatus for processing an image of a tissue sample microarray
US6993169B2 (en) * 2001-01-11 2006-01-31 Trestle Corporation System and method for finding regions of interest for microscopic digital montage imaging
US7002750B2 (en) * 2003-11-06 2006-02-21 Ann-Lun Lee Image capturing device
US7378724B2 (en) * 2005-03-24 2008-05-27 Taiwan Semiconductor Manufacturing Company, Ltd. Cavity structure for semiconductor structures
US7710667B2 (en) * 2008-06-25 2010-05-04 Aptina Imaging Corp. Imaging module with symmetrical lens system and method of manufacture

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992013308A1 (en) * 1991-01-29 1992-08-06 Neuromedical Systems, Inc. Morphological classification system and method
US5933519A (en) * 1994-09-20 1999-08-03 Neo Path, Inc. Cytological slide scoring apparatus
US6151405A (en) * 1996-11-27 2000-11-21 Chromavision Medical Systems, Inc. System and method for cellular specimen grading

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US6993169B2 (en) 2006-01-31
US7212660B2 (en) 2007-05-01
AU2002237779A1 (en) 2002-07-24
US20100002918A1 (en) 2010-01-07
US20020090120A1 (en) 2002-07-11
US7421102B2 (en) 2008-09-02
US7869641B2 (en) 2011-01-11
US20060045320A1 (en) 2006-03-02
US20060029266A1 (en) 2006-02-09
WO2002056256A2 (en) 2002-07-18
US20080123919A1 (en) 2008-05-29

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