WO2002066504A3 - Protein-protein interactions in saccharomyces cerevisiae - Google Patents

Protein-protein interactions in saccharomyces cerevisiae Download PDF

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Publication number
WO2002066504A3
WO2002066504A3 PCT/EP2002/002299 EP0202299W WO02066504A3 WO 2002066504 A3 WO2002066504 A3 WO 2002066504A3 EP 0202299 W EP0202299 W EP 0202299W WO 02066504 A3 WO02066504 A3 WO 02066504A3
Authority
WO
WIPO (PCT)
Prior art keywords
protein
saccharomyces cerevisiae
polypeptides
proteins
interactions
Prior art date
Application number
PCT/EP2002/002299
Other languages
French (fr)
Other versions
WO2002066504A2 (en
Inventor
Pierre Legrain
Original Assignee
Hybrigenics Sa
Pierre Legrain
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hybrigenics Sa, Pierre Legrain filed Critical Hybrigenics Sa
Priority to AU2002251058A priority Critical patent/AU2002251058A1/en
Publication of WO2002066504A2 publication Critical patent/WO2002066504A2/en
Publication of WO2002066504A3 publication Critical patent/WO2002066504A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1055—Protein x Protein interaction, e.g. two hybrid selection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C07K14/395—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts from Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

The present invention relates to proteins that interact with other proteins of Saccharomyces cerevisiae. More specifically, the present invention relates to complexes of polypeptides or polynucleotides encoding the polypeptides, fragments of the polypeptides, antibodies to the complexes, Selected Interacting Domains (SID®) which are identified due to the protein-protein interactions, methods for screening for agents which modulate the interaction of proteins and compositions that are capable of modulating the protein-protein interactions, such as, for example, drug in pharmaceutical composition.
PCT/EP2002/002299 2001-02-16 2002-02-14 Protein-protein interactions in saccharomyces cerevisiae WO2002066504A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002251058A AU2002251058A1 (en) 2001-02-16 2002-02-14 Protein-protein interactions in saccharomyces cerevisiae

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26926601P 2001-02-16 2001-02-16
US60/269,266 2001-02-16

Publications (2)

Publication Number Publication Date
WO2002066504A2 WO2002066504A2 (en) 2002-08-29
WO2002066504A3 true WO2002066504A3 (en) 2003-12-18

Family

ID=23026527

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2002/002299 WO2002066504A2 (en) 2001-02-16 2002-02-14 Protein-protein interactions in saccharomyces cerevisiae

Country Status (2)

Country Link
AU (1) AU2002251058A1 (en)
WO (1) WO2002066504A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2511295A1 (en) * 2011-04-15 2012-10-17 Institut National De La Sante Et De La Recherche Medicale Compositions for preventing and/or treating an infection by an HIV-1 virus

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6083693A (en) * 1996-06-14 2000-07-04 Curagen Corporation Identification and comparison of protein-protein interactions that occur in populations
WO2000066722A1 (en) * 1999-04-30 2000-11-09 Hybrigenics S.A. Collection of prokaryotic dna for two hybrid systems helicobacter pylori protein-protein interactions and application thereof
WO2002050259A2 (en) * 2000-12-18 2002-06-27 National Research Council Of Canada Compositions, methods and kits for identifying protein-protein interaction disrupting agents

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6083693A (en) * 1996-06-14 2000-07-04 Curagen Corporation Identification and comparison of protein-protein interactions that occur in populations
WO2000066722A1 (en) * 1999-04-30 2000-11-09 Hybrigenics S.A. Collection of prokaryotic dna for two hybrid systems helicobacter pylori protein-protein interactions and application thereof
WO2002050259A2 (en) * 2000-12-18 2002-06-27 National Research Council Of Canada Compositions, methods and kits for identifying protein-protein interaction disrupting agents

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
FINLEY R L ET AL: "TWO-HYBRID ANALYSIS OF GENETIC REGULATORY NETWORKS. THE YEAST TWO-HYBRID SYSTEM", YEAST TWO-HYBRID SYSTEM ( ADVANCES IN MOLECULAR BIOLOGY ), XX, XX, PAGE(S) 197-214, XP002922642 *
VIDAL M ET AL: "REVERSE TWO-HYBRID AND ONE-HYBRID SYSTEMS TO DETECT DISSOCIATION OF PROTEIN-PROTEIN AND DNA-PROTEIN INTERACTIONS", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE. WASHINGTON, US, vol. 93, 1 September 1996 (1996-09-01), pages 10315 - 10320, XP000749719, ISSN: 0027-8424 *

Also Published As

Publication number Publication date
AU2002251058A1 (en) 2002-09-04
WO2002066504A2 (en) 2002-08-29

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