WO2002089874A3 - Bubble detector and method of evaluation or calibration thereof - Google Patents

Bubble detector and method of evaluation or calibration thereof Download PDF

Info

Publication number
WO2002089874A3
WO2002089874A3 PCT/US2002/008315 US0208315W WO02089874A3 WO 2002089874 A3 WO2002089874 A3 WO 2002089874A3 US 0208315 W US0208315 W US 0208315W WO 02089874 A3 WO02089874 A3 WO 02089874A3
Authority
WO
WIPO (PCT)
Prior art keywords
bubble detector
bubbles
bubble
conduit
sampled
Prior art date
Application number
PCT/US2002/008315
Other languages
French (fr)
Other versions
WO2002089874A2 (en
Inventor
Derek J Daw
Jeffrey L Creech
William R Patterson
Original Assignee
Therox Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25211382&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2002089874(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Therox Inc filed Critical Therox Inc
Priority to DE60215781T priority Critical patent/DE60215781T2/en
Priority to JP2002587005A priority patent/JP4163005B2/en
Priority to EP02736502A priority patent/EP1372760B1/en
Publication of WO2002089874A2 publication Critical patent/WO2002089874A2/en
Publication of WO2002089874A3 publication Critical patent/WO2002089874A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3622—Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
    • A61M1/36222—Details related to the interface between cassette and machine
    • A61M1/362227—Details related to the interface between cassette and machine the interface providing means for actuating on functional elements of the cassette, e.g. plungers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3622—Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
    • A61M1/36224—Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit with sensing means or components thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3622—Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
    • A61M1/36226—Constructional details of cassettes, e.g. specific details on material or shape
    • A61M1/362262—Details of incorporated reservoirs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3622—Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
    • A61M1/36226—Constructional details of cassettes, e.g. specific details on material or shape
    • A61M1/362265—Details of valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3626—Gas bubble detectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/32—Oxygenators without membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3623—Means for actively controlling temperature of blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/04—Liquids
    • A61M2202/0468—Liquids non-physiological
    • A61M2202/0476—Oxygenated solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2209/00—Ancillary equipment
    • A61M2209/02—Equipment for testing the apparatus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00—Indexing codes associated with group G01N29/00
    • G01N2291/01—Indexing codes associated with the measuring variable
    • G01N2291/015—Attenuation, scattering
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00—Indexing codes associated with group G01N29/00
    • G01N2291/02—Indexing codes associated with the analysed material
    • G01N2291/024—Mixtures
    • G01N2291/02433—Gases in liquids, e.g. bubbles, foams
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2291/00—Indexing codes associated with group G01N29/00
    • G01N2291/02—Indexing codes associated with the analysed material
    • G01N2291/024—Mixtures
    • G01N2291/02466—Biological material, e.g. blood

Abstract

A bubble detector utilizes an ultrasonic transducer to sample bubbles as they pass the transducer. The envelope of the return signal is analyzed to determine the volume of each sampled bubble. If the total volume of bubbles sampled within a certain period of time exceeds a desired maximum volume, the bubble detector may initiate a system shut down. A bubble detector can be evaluated or calibrated by introducing bubbles into a conduit, detecting the bubbles introduced into the conduit using visual inspection or a bubble detector of known resolution and comparing the results with the examination of a bubble detector under evaluation.
PCT/US2002/008315 2001-03-20 2002-03-19 Bubble detector and method of evaluation or calibration thereof WO2002089874A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
DE60215781T DE60215781T2 (en) 2001-03-20 2002-03-19 BLADDER DETECTOR AND CALIBRATION AND EVALUATION METHOD THEREFOR
JP2002587005A JP4163005B2 (en) 2001-03-20 2002-03-19 Bubble detector and evaluation or calibration method thereof
EP02736502A EP1372760B1 (en) 2001-03-20 2002-03-19 Bubble detector and method of evaluation or calibration thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/813,072 2001-03-20
US09/813,072 US6622542B2 (en) 2001-03-20 2001-03-20 Bubble detector and method of use thereof

Publications (2)

Publication Number Publication Date
WO2002089874A2 WO2002089874A2 (en) 2002-11-14
WO2002089874A3 true WO2002089874A3 (en) 2003-05-01

Family

ID=25211382

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/008315 WO2002089874A2 (en) 2001-03-20 2002-03-19 Bubble detector and method of evaluation or calibration thereof

Country Status (7)

Country Link
US (3) US6622542B2 (en)
EP (2) EP1466637B1 (en)
JP (1) JP4163005B2 (en)
AT (2) ATE344068T1 (en)
DE (2) DE60215781T2 (en)
ES (2) ES2361620T3 (en)
WO (1) WO2002089874A2 (en)

Families Citing this family (115)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6852090B2 (en) 1997-02-14 2005-02-08 Nxstage Medical, Inc. Fluid processing systems and methods using extracorporeal fluid flow panels oriented within a cartridge
US6855123B2 (en) 2002-08-02 2005-02-15 Flow Cardia, Inc. Therapeutic ultrasound system
US6554791B1 (en) 1999-09-29 2003-04-29 Smisson-Cartledge Biomedical, Llc Rapid infusion system
US7780619B2 (en) 1999-11-29 2010-08-24 Nxstage Medical, Inc. Blood treatment apparatus
JP2001258881A (en) * 2000-03-16 2001-09-25 Olympus Optical Co Ltd Ultrasonograph
FR2821669B1 (en) * 2001-03-02 2004-08-13 Framatome Anp METHOD AND DEVICE FOR CONTROLLING A SENSOR OF AN INDUSTRIAL INSTALLATION AND A SENSOR MEASUREMENT CHAIN
US7771379B2 (en) * 2001-05-24 2010-08-10 Nxstage Medical, Inc. Functional isolation of upgradeable components to reduce risk in medical treatment devices
KR20010070642A (en) * 2001-05-29 2001-07-27 김경진 Portable hemodialyzer
DE60233415D1 (en) * 2001-08-28 2009-10-01 Mitsubishi Rayon Co DEVICE AND METHOD FOR PRODUCING CARBONATED SOUR WATER AND CARBONATED WATER
US9955994B2 (en) 2002-08-02 2018-05-01 Flowcardia, Inc. Ultrasound catheter having protective feature against breakage
US7335180B2 (en) 2003-11-24 2008-02-26 Flowcardia, Inc. Steerable ultrasound catheter
US6942677B2 (en) 2003-02-26 2005-09-13 Flowcardia, Inc. Ultrasound catheter apparatus
US7022099B2 (en) * 2003-03-17 2006-04-04 Cardiovention, Inc. Extracorporeal blood handling system with automatic flow control and methods of use
US7758510B2 (en) 2003-09-19 2010-07-20 Flowcardia, Inc. Connector for securing ultrasound catheter to transducer
US7092797B2 (en) * 2004-05-25 2006-08-15 Sherwood Services Ag Flow monitoring system for a flow control apparatus
US7540852B2 (en) 2004-08-26 2009-06-02 Flowcardia, Inc. Ultrasound catheter devices and methods
JP2006087545A (en) * 2004-09-22 2006-04-06 Jms Co Ltd Bubble growth degree specification apparatus
IL165365A0 (en) 2004-11-24 2006-01-15 Q Core Ltd Finger-type peristaltic pump
US8308457B2 (en) 2004-11-24 2012-11-13 Q-Core Medical Ltd. Peristaltic infusion pump with locking mechanism
TWI251658B (en) * 2004-12-16 2006-03-21 Ind Tech Res Inst Ultrasonic atomizing cooling apparatus
US8221343B2 (en) 2005-01-20 2012-07-17 Flowcardia, Inc. Vibrational catheter devices and methods for making same
US7975491B2 (en) * 2005-03-17 2011-07-12 Smisson-Cartledge Biomedical Llc Heat exchange system for a pump device
US7563248B2 (en) 2005-03-17 2009-07-21 Smisson-Cartledge Biomedical Llc Infusion fluid heat exchanger and cartridge
DE102005025515A1 (en) * 2005-06-03 2006-12-07 Fresenius Medical Care Deutschland Gmbh Method and apparatus for monitoring a flowing liquid for the presence of air
DE102005025500B3 (en) * 2005-06-03 2006-10-05 Fresenius Medical Care Deutschland Gmbh Monitoring presence of air in flowing liquid such as blood, by determining number of sequential time intervals in which amplitude of received ultrasound signal is less than reference level
JP5175213B2 (en) * 2005-12-22 2013-04-03 ハネウェル・インターナショナル・インコーポレーテッド Portable sample analysis system
US7819834B2 (en) * 2006-01-24 2010-10-26 Terumo Cardiovascular Systems Corp. System and method of air embolism detection and diversion
US7437909B2 (en) * 2006-06-20 2008-10-21 Rudolph Research Analytical Oscillatory measurement device with visual recorder
US8246643B2 (en) 2006-11-07 2012-08-21 Flowcardia, Inc. Ultrasound catheter having improved distal end
US8535025B2 (en) 2006-11-13 2013-09-17 Q-Core Medical Ltd. Magnetically balanced finger-type peristaltic pump
IL179231A0 (en) 2006-11-13 2007-03-08 Q Core Ltd A finger-type peristaltic pump comprising a ribbed anvil
IL179234A0 (en) 2006-11-13 2007-03-08 Q Core Ltd An anti-free flow mechanism
US7661294B2 (en) * 2007-09-21 2010-02-16 Cosense, Inc. Non-invasive multi-function sensor system
US8631683B2 (en) * 2007-02-06 2014-01-21 Fresenius Medical Care Holdings, Inc. Dialysis systems including non-invasive multi-function sensor systems
US7661293B2 (en) * 2007-02-06 2010-02-16 Cosense, Inc. Ultrasonic system for detecting and quantifying of air bubbles/particles in a flowing liquid
US7998115B2 (en) * 2007-02-15 2011-08-16 Baxter International Inc. Dialysis system having optical flowrate detection
US8033157B2 (en) 2007-10-01 2011-10-11 Baxter International Inc. Medical fluid air bubble detection apparatus and method
US9026370B2 (en) 2007-12-18 2015-05-05 Hospira, Inc. User interface improvements for medical devices
US8091442B1 (en) * 2008-04-19 2012-01-10 Cosense, Inc. Positive tube retention arrangement
EP2303362B1 (en) 2008-07-18 2019-06-05 Becton, Dickinson and Company Dual chamber and gear pump assembly for a high pressure delivery system
DE102008034154B4 (en) * 2008-07-22 2011-08-25 Fresenius Medical Care Deutschland GmbH, 61352 Method for operating a pressure measuring device, device with at least one pressure measuring device, device with such a device
US8246564B2 (en) * 2008-12-04 2012-08-21 Therox, Inc. System for enriching a bodily fluid with a gas having automated priming capabilities
US20100143190A1 (en) * 2008-12-04 2010-06-10 Therox, Inc. System for enriching a bodily fluid with a gas having occlusion detection capabilities
US8636952B2 (en) * 2008-12-04 2014-01-28 Therox, Inc. System for enriching a bodily fluid with a gas having a removable gas-enrichment device with an information recording element
US20100143192A1 (en) * 2008-12-04 2010-06-10 Therox, Inc. Method and device for combined detection of bubbles and flow rate in a system for enriching a bodily fluid with a gas
US8192384B2 (en) * 2008-12-04 2012-06-05 Therox, Inc. System for enriching a bodily fluid with a gas having a dual-function power switch mechanism
US8120500B2 (en) * 2008-12-08 2012-02-21 Ecolab Inc. Acoustic fluid presence/absence detection
EP2198778B1 (en) * 2008-12-19 2013-07-03 F. Hoffmann-La Roche AG Infusion device with impedance measurement
EP2370121A1 (en) * 2008-12-22 2011-10-05 CaridianBCT, Inc. Blood processing apparatus with air bubble detector
US8701458B2 (en) * 2009-06-11 2014-04-22 Maquet Critical Care Ab On-demand gas regulator for gas analyzer calibration
EP2448614B1 (en) 2009-07-01 2018-10-10 Fresenius Medical Care Holdings, Inc. Drug delivery devices and related systems and methods
US8207651B2 (en) 2009-09-16 2012-06-26 Tyco Healthcare Group Lp Low energy or minimum disturbance method for measuring frequency response functions of ultrasonic surgical devices in determining optimum operating point
US8371832B2 (en) 2009-12-22 2013-02-12 Q-Core Medical Ltd. Peristaltic pump with linear flow control
US8197438B2 (en) * 2009-12-23 2012-06-12 Roche Diagnostics Operations, Inc. Medicinal fluid delivery systems and methods for priming the same
EP2558147A4 (en) 2010-04-12 2014-12-17 Q Core Medical Ltd Air trap for intravenous pump
US9674811B2 (en) 2011-01-16 2017-06-06 Q-Core Medical Ltd. Methods, apparatus and systems for medical device communication, control and localization
WO2012095827A1 (en) * 2011-01-16 2012-07-19 Q-Core Medical Ltd. Methods, apparatus and systems for metering fluid flow
US10064987B2 (en) 2011-01-31 2018-09-04 Fresenius Medical Care Holdings, Inc. Preventing over-delivery of drug
EP2673018B1 (en) 2011-02-08 2019-04-10 Fresenius Medical Care Holdings, Inc. Magnetic sensors and related systems and methods
US8869612B2 (en) 2011-03-08 2014-10-28 Baxter International Inc. Non-invasive radio frequency liquid level and volume detection system using phase shift
US8353870B2 (en) 2011-04-26 2013-01-15 Fresenius Medical Care Holdings, Inc. Medical temperature sensors and related systems and methods
US9333286B2 (en) 2011-05-12 2016-05-10 Fresenius Medical Care Holdings, Inc. Medical tubing installation detection
US8836519B2 (en) 2011-05-12 2014-09-16 Fresenius Medical Care Holdings, Inc. Determining the absence or presence of fluid in a dialysis system
US9726167B2 (en) 2011-06-27 2017-08-08 Q-Core Medical Ltd. Methods, circuits, devices, apparatuses, encasements and systems for identifying if a medical infusion system is decalibrated
AU2012299169B2 (en) 2011-08-19 2017-08-24 Icu Medical, Inc. Systems and methods for a graphical interface including a graphical representation of medical data
ES2770578T3 (en) 2011-08-19 2020-07-02 Icu Medical Inc Pattern Recognition System and Method for Detecting Clogged Fluid Droplets in a Fluid Delivery Path of an Infusion System
US8854451B2 (en) 2011-10-19 2014-10-07 Lam Research Corporation Automated bubble detection apparatus and method
WO2013090709A1 (en) 2011-12-16 2013-06-20 Hospira, Inc. System for monitoring and delivering medication to a patient and method of using the same to minimize the risks associated with automated therapy
US9603615B2 (en) 2012-01-18 2017-03-28 C.R. Bard, Inc. Vascular re-entry device
WO2013148798A1 (en) 2012-03-30 2013-10-03 Hospira, Inc. Air detection system and method for detecting air in a pump of an infusion system
US9144646B2 (en) 2012-04-25 2015-09-29 Fresenius Medical Care Holdings, Inc. Vial spiking devices and related assemblies and methods
WO2013165473A1 (en) * 2012-05-01 2013-11-07 Therox, Inc. System and method for bubble-free gas-enrichment of flowing liquid within a conduit
CA3089257C (en) 2012-07-31 2023-07-25 Icu Medical, Inc. Patient care system for critical medications
RU2640564C2 (en) 2012-08-02 2018-01-09 Бард Периферэл Васкьюлар Ultrasonic catheter system
US9801756B2 (en) 2012-09-28 2017-10-31 Zoll Circulation, Inc. Intravascular heat exchange catheter and system with RFID coupling
DE102012111375A1 (en) * 2012-11-23 2014-06-12 B. Braun Avitum Ag Method and apparatus for detecting reduced dialysis performance caused by clotting
CN103830791B (en) * 2012-11-27 2017-02-22 深圳先进技术研究院 Automatic peritoneal dialysis machine
DE102012024341B3 (en) * 2012-12-13 2014-02-13 Fresenius Medical Care Deutschland Gmbh Device for monitoring extracorporeal blood circuit of hemodialysis device for detecting air bubbles in blood of patient, has evaluation unit closed in incorrect condition when detection device detects occurrence of bubbles in blood circuit
US9855110B2 (en) 2013-02-05 2018-01-02 Q-Core Medical Ltd. Methods, apparatus and systems for operating a medical device including an accelerometer
AU2014268355B2 (en) 2013-05-24 2018-06-14 Icu Medical, Inc. Multi-sensor infusion system for detecting air or an occlusion in the infusion system
AU2014274122A1 (en) 2013-05-29 2016-01-21 Icu Medical, Inc. Infusion system and method of use which prevents over-saturation of an analog-to-digital converter
ES2838450T3 (en) 2013-05-29 2021-07-02 Icu Medical Inc Infusion set that uses one or more sensors and additional information to make an air determination relative to the infusion set
DE102013018444A1 (en) * 2013-11-05 2015-05-07 Novalung Gmbh Device with a fluid pump, at least two abdominal wall access and fluid pump and abdominal wall connecting hoses
US9474644B2 (en) 2014-02-07 2016-10-25 Zoll Circulation, Inc. Heat exchange system for patient temperature control with multiple coolant chambers for multiple heat exchange modalities
US11033424B2 (en) 2014-02-14 2021-06-15 Zoll Circulation, Inc. Fluid cassette with tensioned polymeric membranes for patient heat exchange system
US10792185B2 (en) 2014-02-14 2020-10-06 Zoll Circulation, Inc. Fluid cassette with polymeric membranes and integral inlet and outlet tubes for patient heat exchange system
US10342917B2 (en) 2014-02-28 2019-07-09 Icu Medical, Inc. Infusion system and method which utilizes dual wavelength optical air-in-line detection
JP2017517302A (en) 2014-05-29 2017-06-29 ホスピーラ インコーポレイテッド Infusion system and pump with configurable closed loop delivery rate catchup
US9784263B2 (en) 2014-11-06 2017-10-10 Zoll Circulation, Inc. Heat exchange system for patient temperature control with easy loading high performance peristaltic pump
US11344668B2 (en) 2014-12-19 2022-05-31 Icu Medical, Inc. Infusion system with concurrent TPN/insulin infusion
US10850024B2 (en) 2015-03-02 2020-12-01 Icu Medical, Inc. Infusion system, device, and method having advanced infusion features
US10444141B2 (en) * 2015-04-02 2019-10-15 Carefusion 303, Inc. Systems and methods for tracking particles in a fluid flow
DE102015004968A1 (en) * 2015-04-20 2016-10-20 Xenios Ag Method for conveying a medium with a pump and pump with a rotor, a housing and a drive
CA3023658C (en) 2016-05-13 2023-03-07 Icu Medical, Inc. Infusion pump system and method with common line auto flush
AU2017277804B2 (en) 2016-06-10 2022-05-26 Icu Medical, Inc. Acoustic flow sensor for continuous medication flow measurements and feedback control of infusion
CN109789269A (en) * 2016-09-29 2019-05-21 皇家飞利浦有限公司 The medical supply with thermal type mass flow sensor for bubble detection
US20180140321A1 (en) 2016-11-23 2018-05-24 C. R. Bard, Inc. Catheter With Retractable Sheath And Methods Thereof
US11596726B2 (en) 2016-12-17 2023-03-07 C.R. Bard, Inc. Ultrasound devices for removing clots from catheters and related methods
US10758256B2 (en) 2016-12-22 2020-09-01 C. R. Bard, Inc. Ultrasonic endovascular catheter
US11116657B2 (en) 2017-02-02 2021-09-14 Zoll Circulation, Inc. Devices, systems and methods for endovascular temperature control
US11185440B2 (en) 2017-02-02 2021-11-30 Zoll Circulation, Inc. Devices, systems and methods for endovascular temperature control
US10582983B2 (en) 2017-02-06 2020-03-10 C. R. Bard, Inc. Ultrasonic endovascular catheter with a controllable sheath
US10089055B1 (en) 2017-12-27 2018-10-02 Icu Medical, Inc. Synchronized display of screen content on networked devices
CN108175909B (en) * 2018-01-29 2020-09-22 英华达（上海）科技有限公司 Ultrasonic bubble detection method and system
CN108680765B (en) * 2018-05-16 2020-07-28 英华达（上海）科技有限公司 Flow velocity sensing device and flow velocity sensing system
US11883626B2 (en) 2019-06-27 2024-01-30 Boston Scientific Scimed, Inc. Detection of an endoscope to a fluid management system
WO2021086952A1 (en) 2019-10-30 2021-05-06 Boston Scientific Limited Fluid monitoring system
ES2933693T3 (en) 2019-11-18 2023-02-13 Eitan Medical Ltd Rapid test for medical pump
US11278671B2 (en) 2019-12-04 2022-03-22 Icu Medical, Inc. Infusion pump with safety sequence keypad
CN113134129A (en) * 2020-01-20 2021-07-20 深圳迈瑞科技有限公司 Infusion pump and infusion pump bubble detection method
US11585715B2 (en) 2020-03-31 2023-02-21 Toyota Research Institute, Inc. Calibration device and calibration procedure for fluid filled sensor
CN111447766B (en) * 2020-05-09 2021-12-03 余正电子科技(嘉兴)有限公司 Convenient, practical and portable novel robot controller
WO2022020184A1 (en) 2020-07-21 2022-01-27 Icu Medical, Inc. Fluid transfer devices and methods of use
US11135360B1 (en) 2020-12-07 2021-10-05 Icu Medical, Inc. Concurrent infusion with common line auto flush
CN114306782B (en) * 2021-12-27 2024-01-26 宁波益诺生智能制造有限公司 Bubble detection end face sealing testing device

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4828543A (en) * 1986-04-03 1989-05-09 Weiss Paul I Extracorporeal circulation apparatus
DE8907919U1 (en) * 1989-06-29 1989-10-05 Albers, Reinhard, 7262 Althengstett, De
US5198776A (en) * 1991-06-26 1993-03-30 Microwave Medical Systems, Inc. Microwave system for detecting gaseous emboli
US6180059B1 (en) * 1995-06-05 2001-01-30 Therox, Inc. Method for the preparation and delivery of gas-enriched fluids

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3695281A (en) * 1970-11-16 1972-10-03 Technicon Instr Method and apparatus for fluid injection
US3974681A (en) 1973-10-23 1976-08-17 Jerry Namery Ultrasonic bubble detector
GB1587160A (en) * 1977-07-06 1981-04-01 Rank Organisation Ltd Analytical apparatus
US4486189A (en) * 1982-09-24 1984-12-04 Extracorporeal Medical Specialties, Inc. Dual mode hemodialysis system
US4651555A (en) * 1984-09-11 1987-03-24 Introtek Corporation Apparatus for detecting discontinuities in a fluid stream
JPH0643723Y2 (en) * 1987-06-26 1994-11-14 ベックマン インスツルメンツ インコーポレーテッド Bubble generator
US5053747A (en) 1989-09-05 1991-10-01 Pacesetter Infusion, Inc. Ultrasonic air-in-line detector self-test technique
US5176631A (en) * 1989-09-05 1993-01-05 Pacesetter Infusion, Ltd. Ultrasonic air-in-line detector for detecting entrained air in a medication infusion system
US5055198A (en) * 1990-03-07 1991-10-08 Shettigar U Ramakrishna Autologous blood recovery membrane system and method
US5039279A (en) * 1990-03-15 1991-08-13 Abbott Laboratories Sensor for detecting fluid flow from a positive displacement pump
US5394732A (en) 1993-09-10 1995-03-07 Cobe Laboratories, Inc. Method and apparatus for ultrasonic detection of air bubbles
GB9524949D0 (en) 1995-12-06 1996-02-07 Kodak Ltd Bubble detector
US6390999B1 (en) * 1996-06-28 2002-05-21 Rocky Mountain Research, Inc. Method and apparatus for flow measurement with temperature and density compensation
US5824881A (en) * 1996-09-13 1998-10-20 Cobe Laboratories Gas/fluid detector for contained fluid systems
US6616633B1 (en) * 1997-09-19 2003-09-09 Alaris Medical Systems, Inc. Apparatus and method for air-in-line detection
US6036645A (en) 1998-01-23 2000-03-14 Transonic Systems, Inc. Ultrasonic probe
US6142008A (en) * 1998-06-12 2000-11-07 Abbott Laboratories Air bubble sensor
US6113554A (en) * 1998-10-16 2000-09-05 Haemonetics Corporation Automatic whole blood collection system
US6408679B1 (en) * 2000-02-04 2002-06-25 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Bubble measuring instrument and method

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4828543A (en) * 1986-04-03 1989-05-09 Weiss Paul I Extracorporeal circulation apparatus
DE8907919U1 (en) * 1989-06-29 1989-10-05 Albers, Reinhard, 7262 Althengstett, De
US5198776A (en) * 1991-06-26 1993-03-30 Microwave Medical Systems, Inc. Microwave system for detecting gaseous emboli
US6180059B1 (en) * 1995-06-05 2001-01-30 Therox, Inc. Method for the preparation and delivery of gas-enriched fluids

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
WOJKE R ET AL: "EIN EINFACHES TESTVERFAHREN ZUR DETEKTION VON MIKROBLASEN IM EXTRAKORPORALEN BLUTKREISLAUF. ÖA SIMPLE TEST PROCEDURE FOR THE DETECTION OF MICROBUBBLES IN THE EXTRACORPOREAL BLOOD CIRCULATION", BIOMEDIZINISCHE TECHNIK, FACHVERLAG SCHIELE UND SCHOEN GMBH. BERLIN, DE, vol. 38, no. 3, 1 March 1993 (1993-03-01), pages 34 - 37, XP000360414, ISSN: 0013-5585 *

Also Published As

Publication number Publication date
US20020134134A1 (en) 2002-09-26
ES2272721T3 (en) 2007-05-01
EP1372760B1 (en) 2006-11-02
EP1466637A2 (en) 2004-10-13
WO2002089874A2 (en) 2002-11-14
EP1372760A2 (en) 2004-01-02
ATE344068T1 (en) 2006-11-15
US6843099B2 (en) 2005-01-18
JP2004528909A (en) 2004-09-24
EP1466637A3 (en) 2005-07-06
US7013703B2 (en) 2006-03-21
US20040154374A1 (en) 2004-08-12
DE60239295D1 (en) 2011-04-07
JP4163005B2 (en) 2008-10-08
EP1466637B1 (en) 2011-02-23
DE60215781D1 (en) 2006-12-14
ES2361620T3 (en) 2011-06-20
US20040089050A1 (en) 2004-05-13
ATE499125T1 (en) 2011-03-15
DE60215781T2 (en) 2007-08-30
US6622542B2 (en) 2003-09-23

Similar Documents

Publication Publication Date Title
WO2002089874A3 (en) Bubble detector and method of evaluation or calibration thereof
NZ590930A (en) Improving the calibration accuracy of a fluidic system by comparing test readings with a calibration curve and then adjusting the signal output
IL151570A0 (en) Method for diagnosing immunologic food sensitivity
EP2382556A4 (en) Method and device for early signal attenuation detection using blood glucose measurements
DE60035174D1 (en) INVASIVE METHOD FOR IN VIVO ANALYTIC MEASUREMENT
WO2001038873A3 (en) Devices and methods for detecting analytes using electrosensor having capture reagent
EP1921435A3 (en) Density measurement with gamma backscattering
CA2635908A1 (en) Method for identifying a muzzle blast within an acoustic signal
EP2851676A3 (en) Method and assembly for determining the temperature of a test sensor
EP1906192A3 (en) Methods and apparatus for evaluating sensors and/or for controlling operation of an apparatus that includes a sensor
WO2004113896A3 (en) System and method for analysis of a biological fluid by the use electrical means
EP2278567A3 (en) Improved sensing apparatus and method
WO2004091387A3 (en) Dual measurement analyte detection system
MX2008013974A (en) Underfill detection system for an electrochemical biosensor.
WO2007005666A3 (en) System and method of analyte detection using differential receptors
WO2003005002A1 (en) Propagation measurement apparatus and propagation measurement method
WO2004036180A3 (en) Systems and methods for the detection of short and long samples
AU2002358775A1 (en) Sensor arrangement
EP1510818A3 (en) Odor discriminating apparatus
WO2002022854A3 (en) Method for the detection and measurement of biomass
WO2003036262A3 (en) Method and apparatus for distinguishing crohn's disease from ulcerative colitis by detecting fecal antibodies to saccharomyces cerevisiae
WO2005019803A3 (en) Measuring analytes from an electromagnetic spectrum using a wavelength router
EP1197744A3 (en) Solution concentration measuring method and solution concentration measuring aparatus
NO20053276L (en) Methods and aids for the detection of mycoplasma.
WO2008029110A3 (en) Electrochemical device with 3 detection areas

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): JP

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 2002587005

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: 2002736502

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2002736502

Country of ref document: EP

WWG Wipo information: grant in national office

Ref document number: 2002736502

Country of ref document: EP