WO2002096484A3 - Apparatus and method for the optical imaging of tissue samples - Google Patents

Apparatus and method for the optical imaging of tissue samples Download PDF

Info

Publication number
WO2002096484A3
WO2002096484A3 PCT/US2002/017202 US0217202W WO02096484A3 WO 2002096484 A3 WO2002096484 A3 WO 2002096484A3 US 0217202 W US0217202 W US 0217202W WO 02096484 A3 WO02096484 A3 WO 02096484A3
Authority
WO
WIPO (PCT)
Prior art keywords
distal end
catheter
fiber arrangement
light
optical
Prior art date
Application number
PCT/US2002/017202
Other languages
French (fr)
Other versions
WO2002096484B1 (en
WO2002096484A2 (en
Inventor
S Eric Ryan
Brett E Bouma
Guillermo J Tearney
Simon Furnish
Jing Tang
Andres Zuluaga
Original Assignee
Infraredx Inc
S Eric Ryan
Brett E Bouma
Guillermo J Tearney
Simon Furnish
Jing Tang
Andres Zuluaga
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Infraredx Inc, S Eric Ryan, Brett E Bouma, Guillermo J Tearney, Simon Furnish, Jing Tang, Andres Zuluaga filed Critical Infraredx Inc
Priority to JP2002592992A priority Critical patent/JP4170771B2/en
Priority to AU2002305766A priority patent/AU2002305766B2/en
Priority to EP02734611A priority patent/EP1411832A4/en
Priority to CA002449111A priority patent/CA2449111A1/en
Publication of WO2002096484A2 publication Critical patent/WO2002096484A2/en
Publication of WO2002096484A3 publication Critical patent/WO2002096484A3/en
Publication of WO2002096484B1 publication Critical patent/WO2002096484B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0084—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for introduction into the body, e.g. by catheters

Abstract

A catheter based optical system (10) for generating data as to the condition of a tissue sample of a mammalian vessel (W). The system includes an elongated catheter shaft (16) having a tissue engaging distal end (18) and a coupled proximal end (20) and an elongated optical delivery fiber arrangement (24) disposed through a lumen of said catheter (16), said optical delivery fiber arrangement (24) having a distal end (28) and a proximal end (32). The distal end of the delivery fiber arrangement (28) has a re-director light emitter (30) thereon for directing light against mammalian tissues (W). An elongated optical collection fiber arrangement (26) is disposed through a lumen of the catheter (16), the optical collection fiber arrangement (26) having distal end (34) and a proximal most end (36). The distal end of the collection fiber arrangement (34) has a re-director light receiver (30) thereon for receiving light reflected from the mammalian tissue (W) by the light emitter (30). The light emitter (42) and the light receiver (40) are longitudinally space (d) apart from one another in the distal end of the catheter (18). The catheter apparatus includes a light source (12) in communication with the delivery fiber (24) and a signal (50) in communication with the receiving fiber (26) for receiving and presenting data collected.
PCT/US2002/017202 2001-05-31 2002-05-30 Apparatus and method for the optical imaging of tissue samples WO2002096484A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2002592992A JP4170771B2 (en) 2001-05-31 2002-05-30 Apparatus and method for optical imaging of tissue samples
AU2002305766A AU2002305766B2 (en) 2001-05-31 2002-05-30 Apparatus and method for the optical imaging of tissue samples
EP02734611A EP1411832A4 (en) 2001-05-31 2002-05-30 Apparatus and method for the optical imaging of tissue samples
CA002449111A CA2449111A1 (en) 2001-05-31 2002-05-30 Apparatus and method for the optical imaging of tissue samples

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/871,578 2001-05-31
US09/871,578 US6654630B2 (en) 2001-05-31 2001-05-31 Apparatus and method for the optical imaging of tissue samples

Publications (3)

Publication Number Publication Date
WO2002096484A2 WO2002096484A2 (en) 2002-12-05
WO2002096484A3 true WO2002096484A3 (en) 2003-07-24
WO2002096484B1 WO2002096484B1 (en) 2003-09-12

Family

ID=25357734

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/017202 WO2002096484A2 (en) 2001-05-31 2002-05-30 Apparatus and method for the optical imaging of tissue samples

Country Status (6)

Country Link
US (1) US6654630B2 (en)
EP (1) EP1411832A4 (en)
JP (1) JP4170771B2 (en)
AU (1) AU2002305766B2 (en)
CA (1) CA2449111A1 (en)
WO (1) WO2002096484A2 (en)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100828427B1 (en) * 2000-02-10 2008-05-08 소니 가부시끼 가이샤 Recording or reproducing method for record medium and recording or reproducing apparatus using record medium
US6738659B2 (en) * 2000-08-31 2004-05-18 Hsu Pei-Feng Optical imaging using the temporal direct reflective signal from a minimized pulse width laser
US20030125630A1 (en) * 2001-12-31 2003-07-03 Furnish Simon M. Catheter probe arrangement for tissue analysis by radiant energy delivery and radiant energy collection
US7672713B2 (en) * 2002-06-19 2010-03-02 Infraredx, Inc. Multi-channel catheter tip
EP1551299A4 (en) * 2002-08-05 2010-01-20 Infraredx Inc Near-infrared spectroscopic analysis of blood vessel walls
US6904199B2 (en) * 2002-08-14 2005-06-07 Infraredx, Inc. Optical catheter with double-clad fiber
US7313432B2 (en) * 2002-10-11 2007-12-25 Infraredx, Inc. Phase discrimination for detection of vulnerable-plaque
US20040092829A1 (en) * 2002-11-07 2004-05-13 Simon Furnish Spectroscope with modified field-of-view
US7616321B2 (en) * 2002-12-04 2009-11-10 Infraredx, Inc. Optical coupler for rotating catheter
US6980573B2 (en) * 2002-12-09 2005-12-27 Infraredx, Inc. Tunable spectroscopic source with power stability and method of operation
US7474407B2 (en) * 2003-02-20 2009-01-06 Applied Science Innovations Optical coherence tomography with 3d coherence scanning
AU2003220024A1 (en) * 2003-03-05 2004-09-28 Infraredx, Inc. Catheter probe arrangement for tissue analysis by radiant energy delivery and radiant energy collection
US7426410B2 (en) * 2003-06-06 2008-09-16 Infraredx, Inc. Spectroscopy of deeply-scattered light
US7742805B2 (en) * 2003-09-05 2010-06-22 Infraredx, Inc. Optical catheter with dual-stage beam redirector
US7894876B2 (en) * 2004-02-02 2011-02-22 Siemens Medical Solutions, Inc. Combined MR-optical coil for prostate, cervix and rectum cancer imaging diagnostics
US7922654B2 (en) * 2004-08-09 2011-04-12 Boston Scientific Scimed, Inc. Fiber optic imaging catheter
AU2005228956B2 (en) 2004-03-23 2011-08-18 Boston Scientific Limited In-vivo visualization system
US11819192B2 (en) 2004-03-23 2023-11-21 Boston Scientific Scimed, Inc. In-vivo visualization system
US7242832B2 (en) 2004-07-27 2007-07-10 Medeikon Corporation Device for tissue characterization
US20060229515A1 (en) * 2004-11-17 2006-10-12 The Regents Of The University Of California Fiber optic evaluation of tissue modification
JP4937991B2 (en) * 2004-12-08 2012-05-23 オリンパス株式会社 Fluorescence endoscope apparatus and imaging unit used therefor
US20070078500A1 (en) * 2005-09-30 2007-04-05 Cornova, Inc. Systems and methods for analysis and treatment of a body lumen
US7450241B2 (en) * 2005-09-30 2008-11-11 Infraredx, Inc. Detecting vulnerable plaque
US20070270717A1 (en) * 2005-09-30 2007-11-22 Cornova, Inc. Multi-faceted optical reflector
US7901441B2 (en) 2005-10-18 2011-03-08 Boston Scientific Scimed, Inc. Method of using an imaging catheter to conduct photodynamic procedures
US7949377B2 (en) 2005-12-14 2011-05-24 Research In Motion Limited Method and apparatus for user equipment directed radio resource control in a UMTS network
US20070219451A1 (en) * 2006-03-03 2007-09-20 John Kula Optical Imaging Balloon Catheters
US20070208257A1 (en) * 2006-03-03 2007-09-06 Furnish Simon M Lateral Viewing Optical Catheters
US20070232931A1 (en) * 2006-03-30 2007-10-04 Kunal Mitra Optical Tomography System Using Short-Pulse Laser for Early Cancer Diagnostics
DK2270570T3 (en) * 2006-04-28 2014-09-15 Moog Inc Optical reflector devices for use in optical rotary joints
EP1858209B1 (en) * 2006-05-17 2010-10-13 Research In Motion Limited Method and system for a signaling connection release indication in an UMTS network
US20070291275A1 (en) * 2006-06-16 2007-12-20 Prescient Medical, Inc. Side-viewing optical acoustic sensors and their use in intravascular diagnostic probes
JP2009544356A (en) * 2006-07-21 2009-12-17 プレサイエント メディカル， インコーポレイテッド Adaptable tissue contact catheter
WO2008021437A2 (en) * 2006-08-14 2008-02-21 Cardio-Optics, Inc. Infrared side imaging of cardiovascular structures and indwelling medical devices
US20090187108A1 (en) * 2006-09-29 2009-07-23 Cornova, Inc. Systems and methods for analysis and treatment of a body lumen
US20080097223A1 (en) * 2006-10-20 2008-04-24 Infraredx, Inc. Optical Catheter Carriage Interlock System and Method
US20080097158A1 (en) * 2006-10-20 2008-04-24 Infraredx, Inc. Noise Suppression System and Method in Catheter Pullback and Rotation System
JP2010507407A (en) * 2006-10-20 2010-03-11 インフラレドックス インコーポレーティッド Optical catheter and pullback rotation system and method
US20080129993A1 (en) * 2006-10-23 2008-06-05 Brennan James F Windowless fiber optic raman spectroscopy probes
US7952706B2 (en) * 2007-05-17 2011-05-31 Prescient Medical, Inc. Multi-channel fiber optic spectroscopy systems employing integrated optics modules
US7952719B2 (en) 2007-06-08 2011-05-31 Prescient Medical, Inc. Optical catheter configurations combining raman spectroscopy with optical fiber-based low coherence reflectometry
WO2008157760A1 (en) * 2007-06-21 2008-12-24 Cornova, Inc. Systems and methods for guiding the analysis and treatment of a body lumen
WO2009014820A1 (en) * 2007-07-20 2009-01-29 Prescient Medical, Inc. Wall-contacting intravascular ultrasound probe catheters
US20090076395A1 (en) * 2007-09-19 2009-03-19 Prescient Medical, Inc. Optimized intravascular ultrasound probe catherers
EP2203733B1 (en) 2007-10-25 2017-05-03 Washington University in St. Louis Confocal photoacoustic microscopy with optical lateral resolution
US20090175576A1 (en) * 2008-01-08 2009-07-09 Cornova, Inc. Shaped fiber ends and methods of making same
US8509880B1 (en) * 2008-02-06 2013-08-13 Remicalm, Llc Handheld portable examination device for diagnostic use
WO2010045437A2 (en) * 2008-10-15 2010-04-22 Cornova, Inc. Systems and methods for analysis and treatment of an occluded body lumen
US9351705B2 (en) 2009-01-09 2016-05-31 Washington University Miniaturized photoacoustic imaging apparatus including a rotatable reflector
WO2010135601A2 (en) * 2009-05-20 2010-11-25 Cornova, Inc. Systems and methods for analysis and treatment of a body lumen
CA2781558C (en) 2009-11-23 2021-06-29 Research In Motion Limited Method and apparatus for state/mode transitioning
WO2011127428A2 (en) 2010-04-09 2011-10-13 Washington University Quantification of optical absorption coefficients using acoustic spectra in photoacoustic tomography
US20120123276A1 (en) * 2010-11-16 2012-05-17 Assaf Govari Catheter with optical contact sensing
US8997572B2 (en) 2011-02-11 2015-04-07 Washington University Multi-focus optical-resolution photoacoustic microscopy with ultrasonic array detection
CN103313643B (en) * 2011-03-31 2015-06-10 奥林巴斯医疗株式会社 Endoscope device, endoscope cap, and analysis method
US8958867B2 (en) 2011-08-29 2015-02-17 Infraredx, Inc. Detection of lipid core plaque cap thickness
US11020006B2 (en) 2012-10-18 2021-06-01 California Institute Of Technology Transcranial photoacoustic/thermoacoustic tomography brain imaging informed by adjunct image data
EP2950878B1 (en) 2013-01-31 2021-10-20 Digma Medical Ltd. Endoluminal duodenal catheter for reducing neural activity
DE102013012236B3 (en) * 2013-07-23 2014-11-06 Spinner Gmbh Rotary coupling for transmitting optical signals along at least two separate optical transmission channels
WO2015077355A1 (en) 2013-11-19 2015-05-28 Washington University Systems and methods of grueneisen-relaxation photoacoustic microscopy and photoacoustic wavefront shaping
US10537387B2 (en) 2014-04-17 2020-01-21 Digma Medical Ltd. Methods and systems for blocking neural activity in an organ of a subject, preferably in the small intestine or the duodenum
US10776654B2 (en) 2015-03-10 2020-09-15 Infraredx, Inc. Assessment of lipid core plaque integrity
US11278206B2 (en) 2015-04-16 2022-03-22 Gentuity, Llc Micro-optic probes for neurology
EP3344126A4 (en) * 2015-08-31 2019-05-08 Gentuity LLC Imaging system includes imaging probe and delivery devices
CN114569245A (en) 2016-08-14 2022-06-03 迪格玛医疗有限公司 Device and method for nerve ablation in the wall of the gastrointestinal tract
US10575904B1 (en) 2016-08-14 2020-03-03 Digma Medical Ltd. Apparatus and method for selective submucosal ablation
US11672426B2 (en) 2017-05-10 2023-06-13 California Institute Of Technology Snapshot photoacoustic photography using an ergodic relay
US11224336B2 (en) * 2017-11-17 2022-01-18 Canon U.S.A., Inc. Rotational extender and/or repeater for rotating fiber based optical imaging systems, and methods and storage mediums for use therewith
WO2019108598A1 (en) 2017-11-28 2019-06-06 Gentuity, Llc Imaging system
EP3836831A4 (en) 2018-08-14 2022-05-18 California Institute of Technology Multifocal photoacoustic microscopy through an ergodic relay
US11592652B2 (en) 2018-09-04 2023-02-28 California Institute Of Technology Enhanced-resolution infrared photoacoustic microscopy and spectroscopy
US10794732B2 (en) * 2018-11-08 2020-10-06 Canon U.S.A., Inc. Apparatus, system and method for correcting nonuniform rotational distortion in an image comprising at least two stationary light transmitted fibers with predetermined position relative to an axis of rotation of at least one rotating fiber
US11369280B2 (en) 2019-03-01 2022-06-28 California Institute Of Technology Velocity-matched ultrasonic tagging in photoacoustic flowgraphy

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5127405A (en) * 1990-02-16 1992-07-07 The Boc Group, Inc. Biomedical fiber optic probe with frequency domain signal processing
US5304173A (en) * 1985-03-22 1994-04-19 Massachusetts Institute Of Technology Spectral diagonostic and treatment system
US5773835A (en) * 1996-06-07 1998-06-30 Rare Earth Medical, Inc. Fiber optic spectroscopy
US5844239A (en) * 1996-05-31 1998-12-01 Kurashiki Boseki Kabushiki Kaisha Optical measuring apparatus for light scattering
US6119031A (en) * 1996-11-21 2000-09-12 Boston Scientific Corporation Miniature spectrometer
US6238348B1 (en) * 1997-07-22 2001-05-29 Scimed Life Systems, Inc. Miniature spectrometer system and method

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3818902A (en) * 1971-07-03 1974-06-25 Olympus Optical Co Endoscope assembly having its optical system provided with a direction shifter
US4027945A (en) 1976-03-04 1977-06-07 The United States Of America As Represented By The Secretary Of The Navy Optical sliprings
JPH0535374Y2 (en) * 1984-12-28 1993-09-08
GB2179173B (en) 1985-08-14 1989-08-16 Nova Scotia Res Found Multiple pass optical fibre rotary joint
US4872737A (en) 1988-09-07 1989-10-10 Hitachi Cable Limited Multi-port fiberoptic rotary joint
US6134003A (en) * 1991-04-29 2000-10-17 Massachusetts Institute Of Technology Method and apparatus for performing optical measurements using a fiber optic imaging guidewire, catheter or endoscope
US6485413B1 (en) * 1991-04-29 2002-11-26 The General Hospital Corporation Methods and apparatus for forward-directed optical scanning instruments
US5425117A (en) * 1994-04-25 1995-06-13 University Of Central Florida Multiple channel rotary optical coupler
US6564088B1 (en) 2000-01-21 2003-05-13 University Of Massachusetts Probe for localized tissue spectroscopy
US6701181B2 (en) * 2001-05-31 2004-03-02 Infraredx, Inc. Multi-path optical catheter

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5304173A (en) * 1985-03-22 1994-04-19 Massachusetts Institute Of Technology Spectral diagonostic and treatment system
US5127405A (en) * 1990-02-16 1992-07-07 The Boc Group, Inc. Biomedical fiber optic probe with frequency domain signal processing
US5844239A (en) * 1996-05-31 1998-12-01 Kurashiki Boseki Kabushiki Kaisha Optical measuring apparatus for light scattering
US5773835A (en) * 1996-06-07 1998-06-30 Rare Earth Medical, Inc. Fiber optic spectroscopy
US6119031A (en) * 1996-11-21 2000-09-12 Boston Scientific Corporation Miniature spectrometer
US6238348B1 (en) * 1997-07-22 2001-05-29 Scimed Life Systems, Inc. Miniature spectrometer system and method

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1411832A4 *

Also Published As

Publication number Publication date
US20020183622A1 (en) 2002-12-05
US6654630B2 (en) 2003-11-25
AU2002305766B2 (en) 2005-09-15
WO2002096484B1 (en) 2003-09-12
WO2002096484A2 (en) 2002-12-05
EP1411832A2 (en) 2004-04-28
EP1411832A4 (en) 2009-07-15
JP4170771B2 (en) 2008-10-22
JP2004538448A (en) 2004-12-24
CA2449111A1 (en) 2002-12-05

Similar Documents

Publication Publication Date Title
WO2002096484A3 (en) Apparatus and method for the optical imaging of tissue samples
US4306547A (en) Rigid fiberoptic laryngoscope
EP2327978A3 (en) Systems and methods for spectroscopy of biological tissue
US5279542A (en) Colon irrigation method
US7470269B2 (en) Ophthalmic surgery light transmitting apparatus
EP0943110B1 (en) Apparatus for rotatably connecting optical fibers
US5408996A (en) System and method for localization of malignant tissue
CN101612050B (en) Endoscope apparatus
CA2376281A1 (en) Visually-directed surgical instrument and method for treating female urinary incontinence
JP2001161640A (en) Surgical operation apparatus with integrated image censor
AU1601992A (en) Laser video endoscope
CN101791246B (en) Near-infrared locating and guiding device for implantation of pedicles nail
ATE556644T1 (en) FORWARD SCANING IMAGING LIGHT FIBER PROBE
WO1999044554A3 (en) Aspirating handpieces for laser surgical operations
WO2007038682A3 (en) Paired angled rotation scanning probes and methods of use
WO2005000096A3 (en) Disposable endoscope and method of making a disposable endoscope
WO2003051183A3 (en) Sheath for guiding imaging instruments
IL185247A0 (en) High throughput endo-illuminator probe
EP1575423A4 (en) A laser-induced fluorescence method for precancerous lesion diagnosis and an endoscope precancerous lesion diagnosis apparatus thereof
EP1201189A3 (en) Light-assisted surgical instrument and method for treating female urinary incontinence
DE59409123D1 (en) ENDOSCOPIC INSTRUMENTS
EP1327414A3 (en) Device for diagnostic imaging of tissues
EP3681366B1 (en) Disposable miniature endoscopy system
JPH06165783A (en) Optical diagnostic device
US20050020938A1 (en) Catheter for insertion into the human body

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SI SK SL TJ TM TN TR TT TZ UA UG US UZ VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
B Later publication of amended claims

Free format text: 20030602

WWE Wipo information: entry into national phase

Ref document number: 2002592992

Country of ref document: JP

Ref document number: 2449111

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2002305766

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 2002734611

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWP Wipo information: published in national office

Ref document number: 2002734611

Country of ref document: EP

WWG Wipo information: grant in national office

Ref document number: 2002305766

Country of ref document: AU