WO2003000155A3 - Compositions and methods for reducing blood and fluid loss from open wounds - Google Patents

Compositions and methods for reducing blood and fluid loss from open wounds Download PDF

Info

Publication number
WO2003000155A3
WO2003000155A3 PCT/US2002/019554 US0219554W WO03000155A3 WO 2003000155 A3 WO2003000155 A3 WO 2003000155A3 US 0219554 W US0219554 W US 0219554W WO 03000155 A3 WO03000155 A3 WO 03000155A3
Authority
WO
WIPO (PCT)
Prior art keywords
open wound
fluid loss
burned skin
methods
gel
Prior art date
Application number
PCT/US2002/019554
Other languages
French (fr)
Other versions
WO2003000155A2 (en
Inventor
Millard Marsden Mershon
Original Assignee
Millard Marsden Mershon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millard Marsden Mershon filed Critical Millard Marsden Mershon
Priority to AU2002350088A priority Critical patent/AU2002350088A1/en
Priority to CA2449436A priority patent/CA2449436C/en
Priority to IL15915602A priority patent/IL159156A0/en
Priority to EP02780883A priority patent/EP1408902A4/en
Publication of WO2003000155A2 publication Critical patent/WO2003000155A2/en
Publication of WO2003000155A3 publication Critical patent/WO2003000155A3/en
Priority to IL159156A priority patent/IL159156A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/008—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0052—Mixtures of macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding

Abstract

The invention described herein relates to methods for reducing and/or stopping bleeding or fluid loss from open wound, denuded tissue, or burned skin, comprising the step of applying to the open wound, denuded tissue or burned skin a gel-fonning composition comprising at least one of the following compositions: a polyacry1ic acid having the structural formula [CH2=CHCO2H]n, where n is between 10,000 and 70,000; a polyacrylic acid and a desiccated water soluble organic or inorganic base; polyacrylic acid and a desiccated poorly soluble basic salt, and a polyvinyl alcohol having the structural formula of [CH2=CHOH]n, where n is between 15,000 and 150,000. When the gel-forming composition is applied to the open wound, denuded tissue, or burned skin, its ions react therein in the presence of water from blood or body fluid therein to form an aqueous gel or mucilage having sufficient viscosity and adhesiveness to cover and adhere to the open wound, denuded tissue, or burned skin so that bleeding or fluid loss is thereby reduced and/or stopped.
PCT/US2002/019554 2001-06-22 2002-06-20 Compositions and methods for reducing blood and fluid loss from open wounds WO2003000155A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
AU2002350088A AU2002350088A1 (en) 2001-06-22 2002-06-20 Compositions and methods for reducing blood and fluid loss from open wounds
CA2449436A CA2449436C (en) 2001-06-22 2002-06-20 Compositions and methods for reducing blood and fluid loss from open wounds
IL15915602A IL159156A0 (en) 2001-06-22 2002-06-20 A gel forming composition containing a polyacrylic acid
EP02780883A EP1408902A4 (en) 2001-06-22 2002-06-20 Compositions and methods for reducing blood and fluid loss from open wounds
IL159156A IL159156A (en) 2001-06-22 2003-12-02 Bioadhesive gel or mucilage containing a carbomer

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30038401P 2001-06-22 2001-06-22
US60/300,384 2001-06-22

Publications (2)

Publication Number Publication Date
WO2003000155A2 WO2003000155A2 (en) 2003-01-03
WO2003000155A3 true WO2003000155A3 (en) 2003-07-03

Family

ID=23158880

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/019554 WO2003000155A2 (en) 2001-06-22 2002-06-20 Compositions and methods for reducing blood and fluid loss from open wounds

Country Status (6)

Country Link
US (1) US7303759B2 (en)
EP (1) EP1408902A4 (en)
AU (1) AU2002350088A1 (en)
CA (1) CA2449436C (en)
IL (2) IL159156A0 (en)
WO (1) WO2003000155A2 (en)

Families Citing this family (67)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10204819A1 (en) * 2002-01-31 2003-08-14 Aesculap Ag & Co Kg Hemostatic agents and their provision for medicine
US20060216267A1 (en) * 2002-08-20 2006-09-28 Kovacs Stephen G Hydrophobic elastomeric polymer chemistry device for inhibiting the growth of onychomycosis and urushiol-induced allergic contact dermatitis
US7074425B2 (en) * 2002-09-26 2006-07-11 Bonewax, Llc Hemostatic compositions and methods
ITMI20030414A1 (en) * 2003-03-06 2004-09-07 Biofarm S R L Ora Biofarmitalia S P A BUFFER WITH GEL LAYER WITH COSMETIC OR THERAPEUTIC ACTIVITY.
CA2539568C (en) * 2003-09-23 2013-09-10 Orthotherapeutics, Llc Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects
WO2005034816A1 (en) 2003-09-23 2005-04-21 Ortho Therapeutics, Llc. Bioabsorbable putty-like hemostatic implants
US7955616B2 (en) * 2003-09-23 2011-06-07 Orthocon, Inc. Absorbable implants and methods for their use in hemostasis and in the treatment of osseous defects
CA2559520A1 (en) * 2004-03-17 2005-09-29 Genzyme Corporation Anti-adhesion spraying
US20060178609A1 (en) 2005-02-09 2006-08-10 Z-Medica, Llc Devices and methods for the delivery of molecular sieve materials for the formation of blood clots
KR20070117589A (en) * 2005-02-15 2007-12-12 버지니아 커먼웰스 유니버시티 Mineral technologies (mt) for acute hemostasis and for the treatment of acute wounds and chronic ulcers
EP1879606B1 (en) * 2005-04-25 2013-06-12 Massachusetts Institute of Technology Self-assembling peptides for promoting hemostasis
US20070129630A1 (en) * 2005-12-07 2007-06-07 Shimko Daniel A Imaging method, device and system
US20070135706A1 (en) * 2005-12-13 2007-06-14 Shimko Daniel A Debridement method, device and kit
WO2008018892A2 (en) * 2005-12-22 2008-02-14 Pluromed, Inc. Methods and kits for treating lacerations and puncture wounds using inverse thermosensitive polymers
KR20110091019A (en) * 2006-04-25 2011-08-10 메사추세츠 인스티튜트 오브 테크놀로지 Compositions and methods for affecting movement of contaminants, bodily fluids or other entities and/or affecting other physiological conditions
US8938898B2 (en) 2006-04-27 2015-01-27 Z-Medica, Llc Devices for the identification of medical products
US7968114B2 (en) 2006-05-26 2011-06-28 Z-Medica Corporation Clay-based hemostatic agents and devices for the delivery thereof
US7604819B2 (en) 2006-05-26 2009-10-20 Z-Medica Corporation Clay-based hemostatic agents and devices for the delivery thereof
US8202532B2 (en) 2006-05-26 2012-06-19 Z-Medica Corporation Clay-based hemostatic agents and devices for the delivery thereof
US20080014251A1 (en) * 2006-07-14 2008-01-17 Advanced Vascular Dynamics Hemostatic compound and its use
AU2007283772B2 (en) * 2006-08-04 2013-03-07 Kensey Nash Corporation Biomimetic compounds and synthetic methods therefor
WO2008127287A2 (en) * 2006-10-11 2008-10-23 Biolife, L.L.C. Materials and methods for wound treatment
GB2447012B (en) * 2007-02-21 2011-03-16 Pharmacure Health Care Ab Composition for combating epistaxis
US20080287987A1 (en) * 2007-05-16 2008-11-20 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Dispensing system for tissue sealants
US7823761B2 (en) * 2007-05-16 2010-11-02 The Invention Science Fund I, Llc Maneuverable surgical stapler
US7922064B2 (en) * 2007-05-16 2011-04-12 The Invention Science Fund, I, LLC Surgical fastening device with cutter
US7798385B2 (en) 2007-05-16 2010-09-21 The Invention Science Fund I, Llc Surgical stapling instrument with chemical sealant
US7832611B2 (en) * 2007-05-16 2010-11-16 The Invention Science Fund I, Llc Steerable surgical stapler
US8485411B2 (en) * 2007-05-16 2013-07-16 The Invention Science Fund I, Llc Gentle touch surgical stapler
US7810691B2 (en) * 2007-05-16 2010-10-12 The Invention Science Fund I, Llc Gentle touch surgical stapler
US8771725B2 (en) 2007-10-12 2014-07-08 Chesson Laboratory Associates, Inc. Poly(urea-urethane) compositions useful as topical medicaments and methods of using the same
US20090112243A1 (en) * 2007-10-25 2009-04-30 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Surgical cutter with dispensing system for tissue sealants
US20090112256A1 (en) * 2007-10-30 2009-04-30 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Suturing device with tissue sealant dispenser
US20110054375A1 (en) * 2007-11-27 2011-03-03 Hans Smola Dressing comprising polyacrylate particles and use thereof
US20090143816A1 (en) * 2007-11-30 2009-06-04 Searete Llc, A Limited Liability Corporation Of The State Of Delaware Grasper with surgical sealant dispenser
GB2460815A (en) * 2008-04-04 2009-12-16 Kays Medical A sterilisable gel formulation comprising calcium gluconate
US20090275904A1 (en) * 2008-05-02 2009-11-05 Sardesai Neil Rajendra Sheet assemblies with releasable medicaments
US8999297B2 (en) * 2008-07-11 2015-04-07 Inter-Med, Inc. Hemostatic agent
WO2010068509A1 (en) * 2008-11-25 2010-06-17 Biolife, L.L.C. Hemostatic wound dressings
WO2010102283A2 (en) * 2009-03-06 2010-09-10 Jack Mentkow Hemostatic agent composition, delivery system and method
US20100226873A1 (en) 2009-03-06 2010-09-09 Biolife, L.L.C. Hemostatic Composition with Magnetite
US8110208B1 (en) 2009-03-30 2012-02-07 Biolife, L.L.C. Hemostatic compositions for arresting blood flow from an open wound or surgical site
US9439941B2 (en) 2009-12-14 2016-09-13 The University Of Hong Kong Nano cancer barrier device (NCBD) to immobilize and inhibit the division of metastic cancer stem cells
US8409628B2 (en) 2010-02-04 2013-04-02 Penguin IP Holdings, Inc. Methods and compositions for oxygenation of skin to treat skin disorders
US20110200683A1 (en) * 2010-02-16 2011-08-18 Piper Medical, Inc Hydrogen peroxide solution producing first aid substance, packaging, and treatment
WO2011123619A2 (en) 2010-03-31 2011-10-06 Penguin Ip Holdings Inc. Permeable mixtures, methods and compositions for the skin
US9119605B2 (en) 2010-05-06 2015-09-01 Zimmer, Inc. Synthetic polymer adhesives and methods for making, using and delivering the same
US8858969B2 (en) 2010-09-22 2014-10-14 Z-Medica, Llc Hemostatic compositions, devices, and methods
WO2012064821A2 (en) 2010-11-09 2012-05-18 Knc Ner Acquisition Sub, Inc. Adhesive compounds and methods use for hernia repair
GB201104175D0 (en) * 2011-03-11 2011-04-27 Medtrade Products Ltd Haemostatic material
PL395069A1 (en) * 2011-05-31 2012-12-03 Warszawski Uniwersytet Medyczny An analgesic pharmaceutical composition for oral administration
US10022083B2 (en) 2011-06-02 2018-07-17 Abdulmohsen E. A. H. Al-Terki Multiple oral and nasal surgical procedures method and kit
US8387798B1 (en) 2012-04-27 2013-03-05 Abdulmohsen E. A. H. Al-Terki Mutiple oral and nasal surgical procedures method and kit
US20130202656A1 (en) 2012-02-03 2013-08-08 Dynasil Biomedical Corporation Systems and kits for the fabrication of tissue patches
US9161869B2 (en) * 2012-03-30 2015-10-20 Kimberly-Clark Worldwide, Inc. Absorbent articles with decolorizing agents
CA3183404A1 (en) 2012-06-22 2013-12-27 Teleflex Life Sciences Limited Hemostatic devices
JP6552115B2 (en) * 2013-03-15 2019-07-31 クック・メディカル・テクノロジーズ・リミテッド・ライアビリティ・カンパニーＣｏｏｋ Ｍｅｄｉｃａｌ Ｔｅｃｈｎｏｌｏｇｉｅｓ Ｌｌｃ Adhesive medical products and methods for treating gastrointestinal tract lesions
US11931227B2 (en) 2013-03-15 2024-03-19 Cook Medical Technologies Llc Bimodal treatment methods and compositions for gastrointestinal lesions with active bleeding
US10238598B2 (en) 2013-12-16 2019-03-26 The University Of British Columbia Self-fueled particles for propulsion through flowing aqueous fluids
US9833538B2 (en) 2015-08-07 2017-12-05 Xcede Technologies, Inc. Adhesive compositions and related methods
US10588998B2 (en) 2015-08-07 2020-03-17 Xcede Technologies, Inc. Adhesive compositions and related methods
US9540548B1 (en) 2015-08-07 2017-01-10 Xcede Technologies, Inc. Adhesive compositions and related methods
IL247786B (en) 2016-09-12 2019-08-29 Plotkin Alexander Wound covering with haemostatic action and the method of its creation
EP3615094A1 (en) * 2017-04-28 2020-03-04 Cook Medical Technologies LLC Bimodal treatment methods and compositions for gastrointestinal lesions with active bleeding
WO2019067680A1 (en) 2017-09-27 2019-04-04 Cook Medical Technologies Llc Crosslinking submucosal injectate system
US20210106717A1 (en) * 2019-10-10 2021-04-15 Cook Medical Technologies Llc Bonded powders for the treatment of bodily lesions
US20230330297A1 (en) * 2022-04-15 2023-10-19 Waldir Teixeira Renó Homeostatic single layer dressing

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6133326A (en) * 1994-08-31 2000-10-17 Pfizer Inc Compositions and methods for decreasing sebum production

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1249458B (en) * 1960-10-14 1967-09-07 Mmisterul Industnei Petrolului si Chimiei Bukarest Film-forming skin protection agent
US4215106A (en) * 1978-04-07 1980-07-29 Annenkova Valentina M Local hemostatic
DE3224382A1 (en) * 1982-06-30 1984-01-12 Beiersdorf Ag, 2000 Hamburg HYDROGEL-BASED FABRIC MATERIAL AND METHOD FOR THE PRODUCTION THEREOF
US4732755A (en) * 1983-01-17 1988-03-22 University Of Health Sciences/The Chicago Medical School Skin burn treatment
US4822349A (en) * 1984-04-25 1989-04-18 Hursey Francis X Method of treating wounds
JPS6270318A (en) * 1985-09-25 1987-03-31 Nippon Kayaku Co Ltd Hemostatic and wound-protecting agent
JPS63220876A (en) * 1987-03-10 1988-09-14 日本曹達株式会社 Wound protecting agent
US5457093A (en) * 1987-09-18 1995-10-10 Ethicon, Inc. Gel formulations containing growth factors
US4920158A (en) * 1989-10-11 1990-04-24 Medipro Sciences Limited Hydrogel-forming wound dressing or skin coating material
AU639844B2 (en) * 1990-11-09 1993-08-05 Otsuka Pharmaceutical Co., Ltd. Procaterol-containing plaster
US5260066A (en) * 1992-01-16 1993-11-09 Srchem Incorporated Cryogel bandage containing therapeutic agent
US5459177A (en) * 1993-03-09 1995-10-17 Sun Medical Co., Ltd. Adhesive for soft tissue and kit thereof
US5858350A (en) * 1993-12-01 1999-01-12 Marine Polymer Technologies Methods and compositions for poly-β-1→4-N-acetylglucosamine cell therapy system
US5578661A (en) * 1994-03-31 1996-11-26 Nepera, Inc. Gel forming system for use as wound dressings
US5891074A (en) * 1996-08-22 1999-04-06 Avitar, Inc. Pressure wound dressing
US6706690B2 (en) * 1999-06-10 2004-03-16 Baxter Healthcare Corporation Hemoactive compositions and methods for their manufacture and use
CA2244017A1 (en) * 1998-07-28 2000-01-28 Stephane Tetreault Moisture-curable adhesive suture strip
US6211296B1 (en) * 1998-11-05 2001-04-03 The B. F. Goodrich Company Hydrogels containing substances
US6060461A (en) * 1999-02-08 2000-05-09 Drake; James Franklin Topically applied clotting material
US6531500B2 (en) * 1999-07-23 2003-03-11 Alwyn Company, Inc. Methods for treatment of inflammatory diseases
IL133473A0 (en) * 1999-12-12 2001-04-30 Avenir R & B Medical Technolog Bactericidal haemostatic preparations for local use and the methods of their production and conservation
US6187347B1 (en) * 2000-02-09 2001-02-13 Ecosafe, Llc. Composition for arresting the flow of blood and method
US6399092B1 (en) * 2000-12-27 2002-06-04 Healthpoint, Ltd. Anhydrous, hydrophilic absorbent wound dressing (tube) with antimicrobials or other pharmaceutically active agents

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6133326A (en) * 1994-08-31 2000-10-17 Pfizer Inc Compositions and methods for decreasing sebum production

Also Published As

Publication number Publication date
CA2449436C (en) 2012-05-01
CA2449436A1 (en) 2003-01-03
EP1408902A2 (en) 2004-04-21
US20030008011A1 (en) 2003-01-09
EP1408902A4 (en) 2008-02-13
US7303759B2 (en) 2007-12-04
AU2002350088A1 (en) 2003-01-08
WO2003000155A2 (en) 2003-01-03
IL159156A (en) 2010-11-30
IL159156A0 (en) 2004-06-01

Similar Documents

Publication Publication Date Title
WO2003000155A3 (en) Compositions and methods for reducing blood and fluid loss from open wounds
KR101506930B1 (en) Improvements relating to skin dressings
KR101506933B1 (en) Improvements relating to skin dressings
AU7168587A (en) Two-step procedure for indolent wound healing and aqueous medium and topical ointment used in connection therewith
ES459938A1 (en) Pharmaceutical insertion compositions and a process for producing the same
AR040305A1 (en) HEMOSTATIC BANDING FOR WOUNDS CONTAINING A MODIFIED POLYACARIDE WITH ALDEHYDE AND HEMOSTATIC AGENTS
AU2003228516A1 (en) Occlusive composition comprising a poly (2-cyanoacrylate) monomer
PT750491E (en) DEODORIZING AND ANTIPERSPIRANT COMPOSITIONS
EP1159972A3 (en) Anti-microbial dressing using metallic compounds
US6652840B1 (en) Bleeding control and healing aid compositions and methods of use
EP1377245A4 (en) Immunostimulating coating for surgical devices
AR040304A1 (en) HEMOSTATIC BANDAGE FOR WOUNDS CONTAINING A MODIFIED POLYACARIDE WITH ALDEHIDO
AU2003282358A1 (en) Compositions for treating infected skin and mucous membrane comprising an anti-microbial agent and an essential oil
CA2294457A1 (en) Pharmaceutical composition for application to mucosa
CA2390556A1 (en) Use of soluble cellulose derivative having been made hardly soluble in water and method for producing it
KR960703628A (en) How to Treat Psoriasis (PSORIASIS TREATMENT)
KR20080018360A (en) A wound-healing dressing patch with hydrogel layer containing chitosan
GB9807298D0 (en) Medicament
CA2411922A1 (en) Composition for pain mediation and apparatus and method of use thereof
FR2652741B1 (en) ANTIMICROBIAL COMPOSITION FOR APPLICATION TO THE SKIN, APPLICATIONS AS A BODY DEODORANT AND CUTANEOUS BACTERICIDE.
EP1190724B8 (en) Use of antifibrinolytic agents for preparing sponges, compresses or dressings
US9345804B2 (en) S-nitrosothiol-generating skin dressings
WO2002058665A8 (en) Skin care composition
MY136987A (en) Ciclesonide contained pharmaceutical composition for application to mucosa
ATE461718T1 (en) AGENT FOR PREVENTING ADHESIONS AND METHOD FOR PREVENTING ADHESIONS

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CO CR CU CZ DE DK DM DZ EC EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ OM PH PL PT RO RU SD SE SG SI SK SL TJ TM TN TR TT TZ UA UG UZ VN YU ZA ZM ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZM ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE TR BF BJ CF CG CI CM GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 159156

Country of ref document: IL

WWE Wipo information: entry into national phase

Ref document number: 2449436

Country of ref document: CA

WWE Wipo information: entry into national phase

Ref document number: 2002780883

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 2002780883

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP