WO2003002189A3 - An ultrasonic surgical instrument for intracorporeal sonodynamic therapy - Google Patents

An ultrasonic surgical instrument for intracorporeal sonodynamic therapy Download PDF

Info

Publication number
WO2003002189A3
WO2003002189A3 PCT/US2002/020431 US0220431W WO03002189A3 WO 2003002189 A3 WO2003002189 A3 WO 2003002189A3 US 0220431 W US0220431 W US 0220431W WO 03002189 A3 WO03002189 A3 WO 03002189A3
Authority
WO
WIPO (PCT)
Prior art keywords
surgical instrument
ultrasonic surgical
semi
permeable membrane
intracorporeal
Prior art date
Application number
PCT/US2002/020431
Other languages
French (fr)
Other versions
WO2003002189A2 (en
Inventor
Inder Raj S Makin
Noppe Jurgen
Maria Marcus Johannes
Original Assignee
Ethicon Endo Surgery Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethicon Endo Surgery Inc filed Critical Ethicon Endo Surgery Inc
Priority to JP2003508426A priority Critical patent/JP4223391B2/en
Priority to CA002451775A priority patent/CA2451775A1/en
Priority to EP02746736A priority patent/EP1408838A4/en
Priority to AU2002316433A priority patent/AU2002316433B2/en
Publication of WO2003002189A2 publication Critical patent/WO2003002189A2/en
Publication of WO2003002189A3 publication Critical patent/WO2003002189A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
    • A61M37/0092—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin using ultrasonic, sonic or infrasonic vibrations, e.g. phonophoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N7/00—Ultrasound therapy

Abstract

The present invention relates, in general, to ultrasonic surgical instruments and, more particularly, to an intracorporeal ultrasonic surgical instrument for sonodynamic therapy. Disclosed is an ultrasonic surgical system (25) comprising: a generator (10) and an instrument (50) comprising: a housing (74); a transducer (65); a semi-permeable membrane (55); a pharmaceutical agent (75); and an agent delivery system (77). The transducer (65) is adapted to convert the electrical energy of the generator into mechanical energy. The pharmaceutical agent (75), delivered into a chamber of the semi-permeable membrane (55), is driven through the semi-permeable membrane (55) by the mechanical energy. A method in accordance with the present invention comprises the steps of: providing a surgical instrument (25) comprising: a housing (74); a transducer (65) connected to the housing (74); a semi-permeable membrane (55); a pharmaceutical agent (75); and an agent delivery system (77); inserting the surgical instrument into a patient; delivering a drug to the patient; and locally activating the drug with the surgical instrument (25).
PCT/US2002/020431 2001-06-29 2002-06-27 An ultrasonic surgical instrument for intracorporeal sonodynamic therapy WO2003002189A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2003508426A JP4223391B2 (en) 2001-06-29 2002-06-27 Ultrasonic surgical instrument for in-body sonodynamic therapy
CA002451775A CA2451775A1 (en) 2001-06-29 2002-06-27 An ultrasonic surgical instrument for intracorporeal sonodynamic therapy
EP02746736A EP1408838A4 (en) 2001-06-29 2002-06-27 An ultrasonic surgical instrument for intracorporeal sonodynamic therapy
AU2002316433A AU2002316433B2 (en) 2001-06-29 2002-06-27 An ultrasonic surgical instrument for intracorporeal sonodynamic therapy

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US30207001P 2001-06-29 2001-06-29
US60/302,070 2001-06-29
US10/180,702 US7135029B2 (en) 2001-06-29 2002-06-26 Ultrasonic surgical instrument for intracorporeal sonodynamic therapy
US10/ 2002-10-15

Publications (2)

Publication Number Publication Date
WO2003002189A2 WO2003002189A2 (en) 2003-01-09
WO2003002189A3 true WO2003002189A3 (en) 2003-04-10

Family

ID=26876572

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/020431 WO2003002189A2 (en) 2001-06-29 2002-06-27 An ultrasonic surgical instrument for intracorporeal sonodynamic therapy

Country Status (6)

Country Link
US (2) US7135029B2 (en)
EP (1) EP1408838A4 (en)
JP (1) JP4223391B2 (en)
AU (1) AU2002316433B2 (en)
CA (1) CA2451775A1 (en)
WO (1) WO2003002189A2 (en)

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Also Published As

Publication number Publication date
EP1408838A2 (en) 2004-04-21
EP1408838A4 (en) 2007-03-28
JP4223391B2 (en) 2009-02-12
CA2451775A1 (en) 2003-01-09
US7135029B2 (en) 2006-11-14
AU2002316433B2 (en) 2007-12-13
WO2003002189A2 (en) 2003-01-09
JP2004534582A (en) 2004-11-18
US20030040698A1 (en) 2003-02-27
US20050131339A1 (en) 2005-06-16

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