WO2003005029A3 - Magnetic nanoparticles for bioseparation application and methods for producing same - Google Patents

Magnetic nanoparticles for bioseparation application and methods for producing same Download PDF

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Publication number
WO2003005029A3
WO2003005029A3 PCT/CA2002/001003 CA0201003W WO03005029A3 WO 2003005029 A3 WO2003005029 A3 WO 2003005029A3 CA 0201003 W CA0201003 W CA 0201003W WO 03005029 A3 WO03005029 A3 WO 03005029A3
Authority
WO
WIPO (PCT)
Prior art keywords
bioseparation
methods
application
particles
magnetic nanoparticles
Prior art date
Application number
PCT/CA2002/001003
Other languages
French (fr)
Other versions
WO2003005029A2 (en
Inventor
Zhenghe Xu
Yunli Gu
Original Assignee
Univ Alberta
Zhenghe Xu
Yunli Gu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Alberta, Zhenghe Xu, Yunli Gu filed Critical Univ Alberta
Priority to AU2002317095A priority Critical patent/AU2002317095A1/en
Publication of WO2003005029A2 publication Critical patent/WO2003005029A2/en
Publication of WO2003005029A3 publication Critical patent/WO2003005029A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles

Abstract

This invention relates to the controlled crystallization of magnetite to form superparamagnetic nanoparticles. The particles are highly crystalline magnetite in the 10 to 250 nm, 10 to 200, 20-200 and preferably 50 to 150 nm diameter range, exhibiting superparamagnetic characteristics with a saturation magnetization of 62 emu/g. The particles are stabilized with a coating such as dextran. These particles have potential applications in biological cell separations, drug delivery and nondestructive clinical diagnosis.
PCT/CA2002/001003 2001-07-03 2002-07-03 Magnetic nanoparticles for bioseparation application and methods for producing same WO2003005029A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002317095A AU2002317095A1 (en) 2001-07-03 2002-07-03 Magnetic nanoparticles for bioseparation application and methods for producing same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30237901P 2001-07-03 2001-07-03
US60/302,379 2001-07-03

Publications (2)

Publication Number Publication Date
WO2003005029A2 WO2003005029A2 (en) 2003-01-16
WO2003005029A3 true WO2003005029A3 (en) 2003-07-10

Family

ID=23167502

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA2002/001003 WO2003005029A2 (en) 2001-07-03 2002-07-03 Magnetic nanoparticles for bioseparation application and methods for producing same

Country Status (2)

Country Link
AU (1) AU2002317095A1 (en)
WO (1) WO2003005029A2 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2352087T3 (en) 2003-02-04 2011-02-15 Bracco Suisse Sa CONTRAST AGENTS FOR ULTRASOUND AND PROCEDURE FOR THE PREPARATION OF THE SAME.
CN1514243A (en) * 2003-04-30 2004-07-21 成都夸常科技有限公司 Method of preceeding qualitative and lor quantitative analysis against target substance its device and marker and detecting reagent box
WO2004102196A1 (en) * 2003-04-30 2004-11-25 Chengdu Kuachang Medical Industrial Limited Apparatus including nanostructures used for separation or analysis, and the preparation and application thereof
GB0313259D0 (en) 2003-06-09 2003-07-16 Consejo Superior Investigacion Magnetic nanoparticles
CN100563718C (en) * 2003-12-22 2009-12-02 伯拉考开发股份有限公司 The inflation microcapsule assembly that is used for the contrast imaging
WO2005070471A2 (en) * 2004-01-20 2005-08-04 Alnis Biosciences, Inc. Articles comprising magnetic material and bioactive agents
US9248204B2 (en) 2004-08-18 2016-02-02 Bracco Suisse S.A. Gas-filled microvesicles composition for contrast imaging
US20060188905A1 (en) 2005-01-17 2006-08-24 Dynal Biotech Asa Process
CN100365012C (en) * 2006-07-04 2008-01-30 湖南大学 Method for separating protein adopting superparamagnetism silicon nanometer granule static adsorption
US8333993B1 (en) 2006-12-29 2012-12-18 University Of Central Florida Research Foundation, Inc. Synthesis of polymer coated ceria nanoparticles for biomedical applications
WO2009127045A1 (en) * 2008-04-16 2009-10-22 Stemcell Technologies Inc. Magnetic particles
TWI437106B (en) * 2008-12-03 2014-05-11 Tatung Co One dimension nano magnetic wires and manufacturing method thereof
IN2013CN00308A (en) * 2010-07-02 2015-07-03 Koninkl Philips Electronics Nv
ES2379915B1 (en) 2010-10-07 2013-03-20 Consejo Superior De Investigaciones Científicas (Csic) PROCEDURE FOR THE COVERING AND FUNCTIONING OF NANOPARTICLES THROUGH MICHAEL REACTION.
US10203325B2 (en) 2011-11-09 2019-02-12 Board Of Trustees Of Michigan State University Metallic nanoparticle synthesis with carbohydrate capping agent
WO2014089464A1 (en) * 2012-12-07 2014-06-12 The Trustees Of Dartmouth College Magnetic nanoparticles, composites, suspensions and colloids with high specific absorption rate (sar)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4452773A (en) * 1982-04-05 1984-06-05 Canadian Patents And Development Limited Magnetic iron-dextran microspheres
US5062991A (en) * 1990-06-04 1991-11-05 Coulter Corporation In situ use of gelatin in the preparation of uniform ferrite particles
US6123920A (en) * 1996-01-10 2000-09-26 Nycomed Imaging As Superparamagnetic contrast media coated with starch and polyalkylene oxides

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4452773A (en) * 1982-04-05 1984-06-05 Canadian Patents And Development Limited Magnetic iron-dextran microspheres
US5062991A (en) * 1990-06-04 1991-11-05 Coulter Corporation In situ use of gelatin in the preparation of uniform ferrite particles
US6123920A (en) * 1996-01-10 2000-09-26 Nycomed Imaging As Superparamagnetic contrast media coated with starch and polyalkylene oxides

Also Published As

Publication number Publication date
WO2003005029A2 (en) 2003-01-16
AU2002317095A1 (en) 2003-01-21

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