WO2003009784A1 - Ophthalmic drug delivery device - Google Patents
Ophthalmic drug delivery device Download PDFInfo
- Publication number
- WO2003009784A1 WO2003009784A1 PCT/US2002/023116 US0223116W WO03009784A1 WO 2003009784 A1 WO2003009784 A1 WO 2003009784A1 US 0223116 W US0223116 W US 0223116W WO 03009784 A1 WO03009784 A1 WO 03009784A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- pharmaceutically active
- active agent
- fluid
- delivery device
- sclera
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
- A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/20—Surgical instruments, devices or methods, e.g. tourniquets for vaccinating or cleaning the skin previous to the vaccination
- A61B17/205—Vaccinating by means of needles or other puncturing devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
- A61F2250/0068—Means for introducing or releasing pharmaceutical products into the body the pharmaceutical product being in a reservoir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
- A61K9/0051—Ocular inserts, ocular implants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
Abstract
Description
Claims
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2003515180A JP4249611B2 (en) | 2001-07-23 | 2002-07-22 | Ophthalmic drug delivery device |
EP02750206A EP1385452B1 (en) | 2001-07-23 | 2002-07-22 | Ophthalmic drug delivery device |
MXPA03011610A MXPA03011610A (en) | 2001-07-23 | 2002-07-22 | Ophthalmic drug delivery device. |
CA002446741A CA2446741C (en) | 2001-07-23 | 2002-07-22 | Ophthalmic drug delivery device |
BR0210287-0A BR0210287A (en) | 2001-07-23 | 2002-07-22 | Ophthalmic drug delivery device |
DE60214697T DE60214697T2 (en) | 2001-07-23 | 2002-07-22 | DEVICE FOR RELEASING AN OPHTHALMIC MEDICINAL PRODUCT |
AU2002319606A AU2002319606B2 (en) | 2001-07-23 | 2002-07-22 | Ophthalmic drug delivery device |
US10/702,210 US6986900B2 (en) | 2001-07-23 | 2003-11-05 | Ophthalmic drug delivery device |
CY20061101597T CY1105762T1 (en) | 2001-07-23 | 2006-11-07 | EYE DRUG DISPENSING DEVICE |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30722601P | 2001-07-23 | 2001-07-23 | |
US60/307,226 | 2001-07-23 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10/702,210 Continuation US6986900B2 (en) | 2001-07-23 | 2003-11-05 | Ophthalmic drug delivery device |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2003009784A1 true WO2003009784A1 (en) | 2003-02-06 |
Family
ID=23188800
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2002/023116 WO2003009784A1 (en) | 2001-07-23 | 2002-07-22 | Ophthalmic drug delivery device |
Country Status (17)
Country | Link |
---|---|
US (1) | US6986900B2 (en) |
EP (1) | EP1385452B1 (en) |
JP (1) | JP4249611B2 (en) |
CN (1) | CN100349562C (en) |
AT (1) | ATE339170T1 (en) |
AU (1) | AU2002319606B2 (en) |
BR (1) | BR0210287A (en) |
CA (1) | CA2446741C (en) |
CY (1) | CY1105762T1 (en) |
DE (1) | DE60214697T2 (en) |
DK (1) | DK1385452T3 (en) |
ES (1) | ES2271301T3 (en) |
MX (1) | MXPA03011610A (en) |
PL (1) | PL204645B1 (en) |
PT (1) | PT1385452E (en) |
WO (1) | WO2003009784A1 (en) |
ZA (1) | ZA200308811B (en) |
Cited By (10)
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JP2007535540A (en) * | 2004-04-30 | 2007-12-06 | アラーガン、インコーポレイテッド | Intravitreal implants combined with photodynamic therapy to improve vision |
EP2004172A2 (en) * | 2006-03-31 | 2008-12-24 | QLT Plug Delivery, Inc. | Drug delivery methods, structures, and compositions for nasolacrimal system |
WO2014056895A1 (en) | 2012-10-08 | 2014-04-17 | Universität Leipzig | A device for a medical treatment of a sclera |
EP2727616A1 (en) * | 2008-01-03 | 2014-05-07 | University Of Southern California | Implantable drug-delivery devices, and apparatus and methods for refilling the devices |
US9050407B2 (en) | 2008-05-08 | 2015-06-09 | Minipumps, Llc | Implantable drug-delivery devices, and apparatus and methods for filling the devices |
US9271866B2 (en) | 2007-12-20 | 2016-03-01 | University Of Southern California | Apparatus and methods for delivering therapeutic agents |
US9452044B2 (en) | 2006-07-11 | 2016-09-27 | Refocus Group, Inc. | Scleral prosthesis for treating presbyopia and other eye disorders and related devices and methods |
US9603997B2 (en) | 2011-03-14 | 2017-03-28 | Minipumps, Llc | Implantable drug pumps and refill devices therefor |
US9919099B2 (en) | 2011-03-14 | 2018-03-20 | Minipumps, Llc | Implantable drug pumps and refill devices therefor |
US10286146B2 (en) | 2011-03-14 | 2019-05-14 | Minipumps, Llc | Implantable drug pumps and refill devices therefor |
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---|---|---|---|---|
EP1154691A4 (en) * | 1999-01-05 | 2004-07-07 | Massachusetts Eye & Ear Infirm | Targeted transscleral controlled release drug delivery to the retina and choroid |
US7431710B2 (en) | 2002-04-08 | 2008-10-07 | Glaukos Corporation | Ocular implants with anchors and methods thereof |
EP2316394B1 (en) | 2001-06-12 | 2016-11-23 | The Johns Hopkins University | Reservoir device for intraocular drug delivery |
WO2003009784A1 (en) * | 2001-07-23 | 2003-02-06 | Alcon, Inc. | Ophthalmic drug delivery device |
WO2003092665A2 (en) * | 2002-05-02 | 2003-11-13 | Massachusetts Eye And Ear Infirmary | Ocular drug delivery systems and use thereof |
WO2004073551A2 (en) * | 2003-02-18 | 2004-09-02 | Massachusetts Eye And Ear Infirmary | Transscleral drug delivery device and related methods |
JP4869930B2 (en) | 2003-08-26 | 2012-02-08 | ヴィスタ サイエンティフィック エルエルシー | Ophthalmic drug supply device |
US20060233858A1 (en) * | 2005-03-08 | 2006-10-19 | Allergan, Inc. | Systems and methods providing targeted intraocular drug delivery |
US20070212397A1 (en) * | 2005-09-15 | 2007-09-13 | Roth Daniel B | Pharmaceutical delivery device and method for providing ocular treatment |
EP2114298B1 (en) | 2006-02-08 | 2022-10-19 | Medtronic, Inc. | Temporarily stiffened mesh prostheses |
US20070282262A1 (en) * | 2006-05-19 | 2007-12-06 | Alcon, Inc. | Surgical system having integral pneumatic manifolds |
US9474645B2 (en) * | 2006-06-21 | 2016-10-25 | Johnson & Johnson Vision Care, Inc. | Punctal plugs for the delivery of active agents |
BRPI0713719A2 (en) * | 2006-06-21 | 2012-10-30 | Johnson & Johnson Vision Care | punctual plugs for delivery of active agents |
DE102007024642A1 (en) | 2007-05-24 | 2008-11-27 | Eyesense Ag | Hydrogel implant for sensor of metabolites on the eye |
WO2010088548A1 (en) | 2009-01-29 | 2010-08-05 | Forsight Labs, Llc | Posterior segment drug delivery |
US8623395B2 (en) | 2010-01-29 | 2014-01-07 | Forsight Vision4, Inc. | Implantable therapeutic device |
US9636255B2 (en) * | 2009-02-13 | 2017-05-02 | Dose Medical Corporation | Uveoscleral drug delivery implant and methods for implanting the same |
US10206813B2 (en) | 2009-05-18 | 2019-02-19 | Dose Medical Corporation | Implants with controlled drug delivery features and methods of using same |
WO2010141729A1 (en) | 2009-06-03 | 2010-12-09 | Forsight Labs, Llc | Anterior segment drug delivery |
US20110105990A1 (en) * | 2009-11-04 | 2011-05-05 | Silvestrini Thomas A | Zonal drug delivery device and method |
US8529492B2 (en) | 2009-12-23 | 2013-09-10 | Trascend Medical, Inc. | Drug delivery devices and methods |
WO2013022801A1 (en) | 2011-08-05 | 2013-02-14 | Forsight Vision4, Inc. | Small molecule delivery with implantable therapeutic device |
PL2600812T3 (en) | 2010-08-05 | 2022-01-24 | Forsight Vision4, Inc. | Apparatus to treat an eye |
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WO2012019139A1 (en) | 2010-08-05 | 2012-02-09 | Forsight Vision4, Inc. | Combined drug delivery methods and apparatus |
US20140031769A1 (en) | 2010-11-19 | 2014-01-30 | Forsight Vision4, Inc. | Therapeutic agent formulations for implanted devices |
US10245178B1 (en) | 2011-06-07 | 2019-04-02 | Glaukos Corporation | Anterior chamber drug-eluting ocular implant |
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US9102105B2 (en) | 2011-09-13 | 2015-08-11 | Vista Scientific Llc | Method for forming an ocular drug delivery device |
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US10010448B2 (en) | 2012-02-03 | 2018-07-03 | Forsight Vision4, Inc. | Insertion and removal methods and apparatus for therapeutic devices |
US8900300B1 (en) | 2012-02-22 | 2014-12-02 | Omega Ophthalmics Llc | Prosthetic capsular bag and method of inserting the same |
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WO2014066775A1 (en) | 2012-10-26 | 2014-05-01 | Forsight Vision5, Inc. | Ophthalmic system for sustained release of drug to eye |
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WO2016168141A1 (en) | 2015-04-13 | 2016-10-20 | Forsight Vision5, Inc. | Ocular insert composition of semi-crystalline or crystalline pharmaceutically active agent |
US10010502B2 (en) | 2015-05-19 | 2018-07-03 | Amorphex Therapeutics Llc | Device that delivers a sustained low-dose of a myopia-suppressing drug, while preserving pupillary function and accommodation |
WO2017040853A1 (en) | 2015-09-02 | 2017-03-09 | Glaukos Corporation | Drug delivery implants with bi-directional delivery capacity |
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JP7009384B2 (en) | 2016-04-05 | 2022-01-25 | フォーサイト・ビジョン フォー・インコーポレーテッド | Implantable eye drug delivery device |
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Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5466233A (en) * | 1994-04-25 | 1995-11-14 | Escalon Ophthalmics, Inc. | Tack for intraocular drug delivery and method for inserting and removing same |
Family Cites Families (64)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US175324A (en) * | 1876-03-28 | Improvement in automatic gates | ||
US188282A (en) * | 1877-03-13 | Improvement in beer-coolers | ||
US3416530A (en) | 1966-03-02 | 1968-12-17 | Richard A. Ness | Eyeball medication dispensing tablet |
US3828777A (en) | 1971-11-08 | 1974-08-13 | Alza Corp | Microporous ocular device |
US4014335A (en) | 1975-04-21 | 1977-03-29 | Alza Corporation | Ocular drug delivery device |
US4300557A (en) * | 1980-01-07 | 1981-11-17 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | Method for treating intraocular malignancies |
US4327725A (en) | 1980-11-25 | 1982-05-04 | Alza Corporation | Osmotic device with hydrogel driving member |
US4624848A (en) | 1984-05-10 | 1986-11-25 | Ciba-Geigy Corporation | Active agent containing hydrogel devices wherein the active agent concentration profile contains a sigmoidal concentration gradient for improved constant release, their manufacture and use |
US5322691A (en) | 1986-10-02 | 1994-06-21 | Sohrab Darougar | Ocular insert with anchoring protrusions |
US5147647A (en) | 1986-10-02 | 1992-09-15 | Sohrab Darougar | Ocular insert for the fornix |
US4853224A (en) | 1987-12-22 | 1989-08-01 | Visionex | Biodegradable ocular implants |
US4997652A (en) | 1987-12-22 | 1991-03-05 | Visionex | Biodegradable ocular implants |
DE3905050A1 (en) | 1989-02-18 | 1990-08-30 | Lohmann Therapie Syst Lts | THERAPEUTIC SYSTEM FOR DELAYED AND CONTROLLED TRANSDERMAL OR TRANSMUCOSAL ADMINISTRATION OF ACTIVE SUBSTANCES (II) |
US4946450A (en) | 1989-04-18 | 1990-08-07 | Biosource Genetics Corporation | Glucan/collagen therapeutic eye shields |
US5164188A (en) | 1989-11-22 | 1992-11-17 | Visionex, Inc. | Biodegradable ocular implants |
DE4022553A1 (en) | 1990-07-16 | 1992-01-23 | Hund Helmut Gmbh | Medical contact lens - with recess contg. therapeutically or diagnostically active substance |
US5290892A (en) | 1990-11-07 | 1994-03-01 | Nestle S.A. | Flexible intraocular lenses made from high refractive index polymers |
US5378475A (en) | 1991-02-21 | 1995-01-03 | University Of Kentucky Research Foundation | Sustained release drug delivery devices |
US5679666A (en) | 1991-11-22 | 1997-10-21 | Alcon Laboratories, Inc. | Prevention and treatment of ocular neovascularization by treatment with angiostatic steroids |
US5770592A (en) | 1991-11-22 | 1998-06-23 | Alcon Laboratories, Inc. | Prevention and treatment of ocular neovascularization using angiostatic steroids |
US5178635A (en) | 1992-05-04 | 1993-01-12 | Allergan, Inc. | Method for determining amount of medication in an implantable device |
FR2690846B1 (en) | 1992-05-05 | 1995-07-07 | Aiache Jean Marc | GALENIC FORM FOR EYE ADMINISTRATION AND METHOD OF PREPARATION. |
WO1994005257A1 (en) | 1992-09-08 | 1994-03-17 | Allergan, Inc. | Sustained release of ophthalmic drugs from a soluble polymer drug delivery vehicle |
WO1995003009A1 (en) | 1993-07-22 | 1995-02-02 | Oculex Pharmaceuticals, Inc. | Method of treatment of macular degeneration |
US5443505A (en) | 1993-11-15 | 1995-08-22 | Oculex Pharmaceuticals, Inc. | Biocompatible ocular implants |
US5516522A (en) | 1994-03-14 | 1996-05-14 | Board Of Supervisors Of Louisiana State University | Biodegradable porous device for long-term drug delivery with constant rate release and method of making the same |
EP0754046A1 (en) | 1994-04-04 | 1997-01-22 | FREEMAN, William R. | Use of phosphonylmethoxyalkyl nucleosides for the treatment of raised intraocular pressure |
US5710165A (en) | 1994-07-06 | 1998-01-20 | Synthelabo | Use of polyamine antagonists for the treatment of glaucoma |
AUPM897594A0 (en) | 1994-10-25 | 1994-11-17 | Daratech Pty Ltd | Controlled release container |
ATE232089T1 (en) * | 1994-11-10 | 2003-02-15 | Univ Kentucky Res Found | CONTROLLED RELEASE IMPLANTABLE REFILLABLE DEVICE FOR ADMINISTERING DRUGS IMMEDIATELY TO AN INTERNAL PART OF THE BODY |
US5725493A (en) | 1994-12-12 | 1998-03-10 | Avery; Robert Logan | Intravitreal medicine delivery |
US5972326A (en) * | 1995-04-18 | 1999-10-26 | Galin; Miles A. | Controlled release of pharmaceuticals in the anterior chamber of the eye |
AU5857396A (en) | 1995-05-14 | 1996-11-29 | Optonol Ltd. | Intraocular implant, delivery device, and method of implanta tion |
US5773019A (en) | 1995-09-27 | 1998-06-30 | The University Of Kentucky Research Foundation | Implantable controlled release device to deliver drugs directly to an internal portion of the body |
AUPN605795A0 (en) | 1995-10-19 | 1995-11-09 | F.H. Faulding & Co. Limited | Analgesic pharmaceutical composition |
US5743274A (en) | 1996-03-18 | 1998-04-28 | Peyman; Gholam A. | Macular bandage for use in the treatment of subretinal neovascular members |
US5824073A (en) | 1996-03-18 | 1998-10-20 | Peyman; Gholam A. | Macular indentor for use in the treatment of subretinal neovascular membranes |
US5904144A (en) | 1996-03-22 | 1999-05-18 | Cytotherapeutics, Inc. | Method for treating ophthalmic diseases |
JP3309175B2 (en) | 1996-03-25 | 2002-07-29 | 参天製薬株式会社 | Scleral plug containing proteinaceous drug |
US5797898A (en) | 1996-07-02 | 1998-08-25 | Massachusetts Institute Of Technology | Microchip drug delivery devices |
US6120460A (en) | 1996-09-04 | 2000-09-19 | Abreu; Marcio Marc | Method and apparatus for signal acquisition, processing and transmission for evaluation of bodily functions |
ZA9710342B (en) | 1996-11-25 | 1998-06-10 | Alza Corp | Directional drug delivery stent and method of use. |
AU729870B2 (en) | 1997-03-31 | 2001-02-15 | Alza Corporation | Diffusional implantable delivery system |
EP1003569B1 (en) | 1997-08-11 | 2004-10-20 | Allergan, Inc. | Sterile bioerodible implant device containing retinoid with improved biocompatability and method of manufacture |
US5902598A (en) | 1997-08-28 | 1999-05-11 | Control Delivery Systems, Inc. | Sustained release drug delivery devices |
US6066671A (en) | 1997-12-19 | 2000-05-23 | Alcon Laboratories, Inc. | Treatment of GLC1A glaucoma with 3-benzoyl-phenylacetic acids, esters, or amides |
JP2002506028A (en) | 1998-03-13 | 2002-02-26 | ジョンズ ホプキンズ ユニヴァーシティ スクール オヴ メディシン | Use of a protein tyrosine inhibitor such as genistein in the treatment of diabetic retinopathy or ocular inflammation |
US6378526B1 (en) | 1998-08-03 | 2002-04-30 | Insite Vision, Incorporated | Methods of ophthalmic administration |
US6146366A (en) | 1998-11-03 | 2000-11-14 | Ras Holding Corp | Device for the treatment of macular degeneration and other eye disorders |
US6399655B1 (en) | 1998-12-22 | 2002-06-04 | Johns Hopkins University, School Of Medicine | Method for the prophylactic treatment of cataracts |
US6217895B1 (en) | 1999-03-22 | 2001-04-17 | Control Delivery Systems | Method for treating and/or preventing retinal diseases with sustained release corticosteroids |
US6416777B1 (en) | 1999-10-21 | 2002-07-09 | Alcon Universal Ltd. | Ophthalmic drug delivery device |
PT1221918E (en) | 1999-10-21 | 2005-06-30 | Alcon Inc | ADMINISTRATION OF SUB-TENON DRUGS |
CN1292721C (en) * | 1999-10-21 | 2007-01-03 | 爱尔康公司 | Drug delivery device |
RU2149615C1 (en) | 1999-11-10 | 2000-05-27 | Нестеров Аркадий Павлович | Method for introducing drugs in treating posterior eye segment diseases |
AUPQ496500A0 (en) | 2000-01-06 | 2000-02-03 | University Of Sydney, The | Kit |
CN100408118C (en) * | 2000-01-12 | 2008-08-06 | 贝克顿迪肯森公司 | Systems and methods for reducing intraocular pressure |
US6375972B1 (en) | 2000-04-26 | 2002-04-23 | Control Delivery Systems, Inc. | Sustained release drug delivery devices, methods of use, and methods of manufacturing thereof |
ES2312456T3 (en) | 2000-08-30 | 2009-03-01 | Johns Hopkins University | DEVICES FOR INTRAOCULAR SUPPLY OF PHARMACOS. |
CA2433032C (en) | 2001-01-03 | 2008-11-25 | Bausch & Lomb Incorporated | Sustained release drug delivery devices with coated drug cores |
US7181287B2 (en) | 2001-02-13 | 2007-02-20 | Second Sight Medical Products, Inc. | Implantable drug delivery device |
US6713081B2 (en) | 2001-03-15 | 2004-03-30 | The United States Of America As Represented By The Department Of Health And Human Services | Ocular therapeutic agent delivery devices and methods for making and using such devices |
EP2316394B1 (en) | 2001-06-12 | 2016-11-23 | The Johns Hopkins University | Reservoir device for intraocular drug delivery |
WO2003009784A1 (en) * | 2001-07-23 | 2003-02-06 | Alcon, Inc. | Ophthalmic drug delivery device |
-
2002
- 2002-07-22 WO PCT/US2002/023116 patent/WO2003009784A1/en active IP Right Grant
- 2002-07-22 MX MXPA03011610A patent/MXPA03011610A/en active IP Right Grant
- 2002-07-22 EP EP02750206A patent/EP1385452B1/en not_active Expired - Lifetime
- 2002-07-22 CN CNB028136357A patent/CN100349562C/en not_active Expired - Fee Related
- 2002-07-22 PT PT02750206T patent/PT1385452E/en unknown
- 2002-07-22 PL PL369246A patent/PL204645B1/en not_active IP Right Cessation
- 2002-07-22 BR BR0210287-0A patent/BR0210287A/en not_active Application Discontinuation
- 2002-07-22 CA CA002446741A patent/CA2446741C/en not_active Expired - Fee Related
- 2002-07-22 AU AU2002319606A patent/AU2002319606B2/en not_active Ceased
- 2002-07-22 DK DK02750206T patent/DK1385452T3/en active
- 2002-07-22 JP JP2003515180A patent/JP4249611B2/en not_active Expired - Fee Related
- 2002-07-22 ES ES02750206T patent/ES2271301T3/en not_active Expired - Lifetime
- 2002-07-22 AT AT02750206T patent/ATE339170T1/en active
- 2002-07-22 DE DE60214697T patent/DE60214697T2/en not_active Expired - Lifetime
-
2003
- 2003-11-05 US US10/702,210 patent/US6986900B2/en not_active Expired - Fee Related
- 2003-11-12 ZA ZA200308811A patent/ZA200308811B/en unknown
-
2006
- 2006-11-07 CY CY20061101597T patent/CY1105762T1/en unknown
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5466233A (en) * | 1994-04-25 | 1995-11-14 | Escalon Ophthalmics, Inc. | Tack for intraocular drug delivery and method for inserting and removing same |
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Also Published As
Publication number | Publication date |
---|---|
DE60214697T2 (en) | 2007-09-13 |
EP1385452B1 (en) | 2006-09-13 |
EP1385452A1 (en) | 2004-02-04 |
PL369246A1 (en) | 2005-04-18 |
US20040092911A1 (en) | 2004-05-13 |
ES2271301T3 (en) | 2007-04-16 |
CA2446741A1 (en) | 2003-02-06 |
DE60214697D1 (en) | 2006-10-26 |
JP2004535886A (en) | 2004-12-02 |
ATE339170T1 (en) | 2006-10-15 |
DK1385452T3 (en) | 2007-01-15 |
JP4249611B2 (en) | 2009-04-02 |
EP1385452A4 (en) | 2006-01-18 |
CN100349562C (en) | 2007-11-21 |
CA2446741C (en) | 2009-09-29 |
BR0210287A (en) | 2005-12-13 |
CY1105762T1 (en) | 2011-02-02 |
CN1630494A (en) | 2005-06-22 |
PT1385452E (en) | 2006-12-29 |
US6986900B2 (en) | 2006-01-17 |
PL204645B1 (en) | 2010-01-29 |
AU2002319606B2 (en) | 2006-09-14 |
ZA200308811B (en) | 2004-11-23 |
MXPA03011610A (en) | 2004-07-01 |
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