WO2003020884A3 - Method for rapid generation of mature dendritic cells - Google Patents
Method for rapid generation of mature dendritic cells Download PDFInfo
- Publication number
- WO2003020884A3 WO2003020884A3 PCT/US2002/025732 US0225732W WO03020884A3 WO 2003020884 A3 WO2003020884 A3 WO 2003020884A3 US 0225732 W US0225732 W US 0225732W WO 03020884 A3 WO03020884 A3 WO 03020884A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- mature dendritic
- dendritic cells
- dendritic cell
- rapid generation
- methods
- Prior art date
Links
- 210000004443 dendritic cell Anatomy 0.000 title abstract 6
- 238000000034 method Methods 0.000 title abstract 5
- 239000002243 precursor Substances 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 238000000338 in vitro Methods 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4615—Dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
- A61K39/4622—Antigen presenting cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4648—Bacterial antigens
- A61K39/46482—Clostridium, e.g. Clostridium tetani
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5158—Antigen-pulsed cells, e.g. T-cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/05—Adjuvants
- C12N2501/056—Immunostimulating oligonucleotides, e.g. CpG
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2002361468A AU2002361468A1 (en) | 2001-08-14 | 2002-08-13 | Method for rapid generation of mature dendritic cells |
US10/486,755 US7354909B2 (en) | 2001-08-14 | 2002-08-13 | Method for rapid generation of mature dendritic cells |
US12/058,213 US7959934B2 (en) | 2001-08-14 | 2008-03-28 | Method for rapid generation of mature dendritic cells |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31219001P | 2001-08-14 | 2001-08-14 | |
US60/312,190 | 2001-08-14 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US10486755 A-371-Of-International | 2002-08-13 | ||
US12/058,213 Continuation US7959934B2 (en) | 2001-08-14 | 2008-03-28 | Method for rapid generation of mature dendritic cells |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2003020884A2 WO2003020884A2 (en) | 2003-03-13 |
WO2003020884A3 true WO2003020884A3 (en) | 2004-09-16 |
Family
ID=23210279
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2002/025732 WO2003020884A2 (en) | 2001-08-14 | 2002-08-13 | Method for rapid generation of mature dendritic cells |
Country Status (3)
Country | Link |
---|---|
US (2) | US7354909B2 (en) |
AU (1) | AU2002361468A1 (en) |
WO (1) | WO2003020884A2 (en) |
Cited By (1)
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US8871732B2 (en) | 2002-12-23 | 2014-10-28 | Dynavax Technologies Corporation | Immunostimulatory sequence oligonucleotides and methods of using the same |
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AU2002361468A1 (en) | 2003-03-18 |
WO2003020884A2 (en) | 2003-03-13 |
US20080241176A1 (en) | 2008-10-02 |
US20040241841A1 (en) | 2004-12-02 |
US7959934B2 (en) | 2011-06-14 |
US7354909B2 (en) | 2008-04-08 |
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