WO2003026715A3 - Monolayer modification to gold coated stents to reduce adsorption of protein - Google Patents

Monolayer modification to gold coated stents to reduce adsorption of protein Download PDF

Info

Publication number
WO2003026715A3
WO2003026715A3 PCT/US2001/049788 US0149788W WO03026715A3 WO 2003026715 A3 WO2003026715 A3 WO 2003026715A3 US 0149788 W US0149788 W US 0149788W WO 03026715 A3 WO03026715 A3 WO 03026715A3
Authority
WO
WIPO (PCT)
Prior art keywords
protein
coated stents
gold coated
reduce adsorption
monolayer modification
Prior art date
Application number
PCT/US2001/049788
Other languages
French (fr)
Other versions
WO2003026715A2 (en
Inventor
Chuanting You
Original Assignee
Scimed Life Systems Inc
Chuanting You
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scimed Life Systems Inc, Chuanting You filed Critical Scimed Life Systems Inc
Priority to EP01989249A priority Critical patent/EP1387704B1/en
Priority to DE60139083T priority patent/DE60139083D1/en
Priority to AT01989249T priority patent/ATE434453T1/en
Publication of WO2003026715A2 publication Critical patent/WO2003026715A2/en
Publication of WO2003026715A3 publication Critical patent/WO2003026715A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/02—Inorganic materials
    • A61L31/022—Metals or alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/082—Inorganic materials
    • A61L31/088—Other specific inorganic materials not covered by A61L31/084 or A61L31/086
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes

Abstract

A stent has a body and a surface with at least a portion of the surface comprising metal with a coating thereon. The coating is selected from the group consisting of thiols and disulfides and combinations thereof. The thiols are of the form R-SH and the disulfide of the form R-S-S-R' where R is an alkyl group and R' is an alkyl group. The metal is selected from the group consisting of noble metals, silver and copper.
PCT/US2001/049788 2000-12-26 2001-12-18 Monolayer modification to gold coated stents to reduce adsorption of protein WO2003026715A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP01989249A EP1387704B1 (en) 2000-12-26 2001-12-18 Monolayer modification to gold coated stents to reduce adsorption of protein
DE60139083T DE60139083D1 (en) 2000-12-26 2001-12-18 OSAGE TO REDUCE PROTEIN ADSORPTION
AT01989249T ATE434453T1 (en) 2000-12-26 2001-12-18 MODIFICATION OF GOLD-COATED STENTS WITH MONOLAYERS TO REDUCE PROTEIN ADSORPTION

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/681,080 US6398806B1 (en) 2000-12-26 2000-12-26 Monolayer modification to gold coated stents to reduce adsorption of protein
US09/681,080 2000-12-26

Publications (2)

Publication Number Publication Date
WO2003026715A2 WO2003026715A2 (en) 2003-04-03
WO2003026715A3 true WO2003026715A3 (en) 2003-12-04

Family

ID=24733725

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/049788 WO2003026715A2 (en) 2000-12-26 2001-12-18 Monolayer modification to gold coated stents to reduce adsorption of protein

Country Status (6)

Country Link
US (2) US6398806B1 (en)
EP (1) EP1387704B1 (en)
AT (1) ATE434453T1 (en)
DE (1) DE60139083D1 (en)
ES (1) ES2329113T3 (en)
WO (1) WO2003026715A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
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US8974517B2 (en) 2000-12-28 2015-03-10 Abbott Cardiovascular Systems Inc. Thermoelastic and superelastic NI-TI-W alloy

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JP2010503491A (en) 2006-09-15 2010-02-04 ボストン サイエンティフィック リミテッド Bioerodible endoprosthesis with biologically stable inorganic layers
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8974517B2 (en) 2000-12-28 2015-03-10 Abbott Cardiovascular Systems Inc. Thermoelastic and superelastic NI-TI-W alloy

Also Published As

Publication number Publication date
US6398806B1 (en) 2002-06-04
EP1387704A2 (en) 2004-02-11
EP1387704B1 (en) 2009-06-24
US20020103530A1 (en) 2002-08-01
ATE434453T1 (en) 2009-07-15
WO2003026715A2 (en) 2003-04-03
DE60139083D1 (en) 2009-08-06
ES2329113T3 (en) 2009-11-23
US20020082676A1 (en) 2002-06-27

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