WO2003028582A3 - Bovine pregnancy test - Google Patents

Bovine pregnancy test Download PDF

Info

Publication number
WO2003028582A3
WO2003028582A3 PCT/US2002/030459 US0230459W WO03028582A3 WO 2003028582 A3 WO2003028582 A3 WO 2003028582A3 US 0230459 W US0230459 W US 0230459W WO 03028582 A3 WO03028582 A3 WO 03028582A3
Authority
WO
WIPO (PCT)
Prior art keywords
pregnancy
antigens
group
pregnancy test
mid
Prior art date
Application number
PCT/US2002/030459
Other languages
French (fr)
Other versions
WO2003028582A2 (en
Inventor
J W Roth
Mark Colgin
Roger Hurst
Diane Newman
Cathy Landmann
Original Assignee
Aspenbio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aspenbio Inc filed Critical Aspenbio Inc
Priority to AU2002330102A priority Critical patent/AU2002330102A1/en
Publication of WO2003028582A2 publication Critical patent/WO2003028582A2/en
Publication of WO2003028582A3 publication Critical patent/WO2003028582A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61D—VETERINARY INSTRUMENTS, IMPLEMENTS, TOOLS, OR METHODS
    • A61D17/00—Devices for indicating trouble during labour of animals ; Methods or instruments for detecting pregnancy-related states of animals
    • A61D17/006—Devices for indicating trouble during labour of animals ; Methods or instruments for detecting pregnancy-related states of animals for detecting pregnancy of animals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/36—Gynecology or obstetrics
    • G01N2800/368—Pregnancy complicated by disease or abnormalities of pregnancy, e.g. preeclampsia, preterm labour

Abstract

This invention provides bovine pregnancy test methods and devices. The test is also suitable for other ruminant and/or ungulate animals. Antigens from Group A (early pregnancy antigens), and/or Group B (mid-pregnancy antigens), and Group C (early, mid- and late pregnancy antigens) are detected in a fluid from the animal, and pregnancy is reliably determined. The pregnancy assays of this invention are preferably carried out using immunoassay devices which provide immediate results in the field.
PCT/US2002/030459 2001-09-28 2002-09-24 Bovine pregnancy test WO2003028582A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002330102A AU2002330102A1 (en) 2001-09-28 2002-09-24 Bovine pregnancy test

Applications Claiming Priority (20)

Application Number Priority Date Filing Date Title
US32566301P 2001-09-28 2001-09-28
US60/325,663 2001-09-28
US33787101P 2001-11-08 2001-11-08
US60/337,871 2001-11-08
US37735502P 2002-05-02 2002-05-02
US38004202P 2002-05-02 2002-05-02
US37782902P 2002-05-02 2002-05-02
US37716502P 2002-05-02 2002-05-02
US37716602P 2002-05-02 2002-05-02
US38004302P 2002-05-02 2002-05-02
US37792102P 2002-05-02 2002-05-02
US37798702P 2002-05-02 2002-05-02
US60/377,355 2002-05-02
US60/377,987 2002-05-02
US60/380,043 2002-05-02
US60/377,829 2002-05-02
US60/380,042 2002-05-02
US60/377,166 2002-05-02
US60/377,921 2002-05-02
US60/377,165 2002-05-02

Publications (2)

Publication Number Publication Date
WO2003028582A2 WO2003028582A2 (en) 2003-04-10
WO2003028582A3 true WO2003028582A3 (en) 2003-06-19

Family

ID=27581237

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/030459 WO2003028582A2 (en) 2001-09-28 2002-09-24 Bovine pregnancy test

Country Status (3)

Country Link
US (2) US7393696B2 (en)
AU (1) AU2002330102A1 (en)
WO (1) WO2003028582A2 (en)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR015549A1 (en) * 1998-03-20 2001-05-02 Univ Missouri METHOD TO INFERATE THE PRESS IN A BOVINE ANIMAL.
AU2002366097B2 (en) * 2001-11-20 2008-09-18 Monsanto Technology Llc Compositions and methods for accurate early pregnancy diagnosis
CA2483958A1 (en) 2002-05-02 2003-11-13 Aspenbio, Inc. Pregnancy detection
WO2004059282A2 (en) * 2002-12-19 2004-07-15 Monsanto Technology Llc Method and means for early detection of pregnancy in animals by combination testing
US7604950B2 (en) * 2004-04-29 2009-10-20 Monsanto Technology Llc Methods for early detection of pregnancy in cows
US20080026384A1 (en) * 2005-09-30 2008-01-31 Hansen Thomas R Methods and compositions for the detection of bovine pregnancy
WO2007082259A2 (en) * 2006-01-11 2007-07-19 The University Of Wyoming Surrogate markers for viral infections and other inflammatory responses
NZ586100A (en) * 2007-12-13 2012-07-27 Monsanto Technology Llc Compositions and methods for early pregnancy diagnosis using antibodies for pregancy-associated glycoproteins (PAGs)
GB0724870D0 (en) * 2007-12-21 2008-01-30 Univ Lincoln The Preparation of metal colloids
US8192946B2 (en) * 2008-04-10 2012-06-05 The Curators Of The University Of Missouri Assays for detecting pregnancy-associated glycoproteins
US8012770B2 (en) 2009-07-31 2011-09-06 Invisible Sentinel, Inc. Device for detection of antigens and uses thereof
MX2012004105A (en) 2009-10-09 2012-09-07 Invisible Sentinel Inc Device for detection of antigens and uses thereof.
EP2465469A1 (en) * 2010-12-19 2012-06-20 Leo Vankrieken Device for predicting the optimum insemination time for an animal
EP2668501B1 (en) 2011-01-27 2019-06-12 Invisible Sentinel, Inc. Analyte detection devices, multiplex and tabletop devices for detection of analytes, and uses thereof
US8541187B2 (en) 2011-03-01 2013-09-24 Bio Tracking, LLC Systems and methods for detecting animal pregnancy
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
PT2782584T (en) 2011-11-23 2021-09-02 Therapeuticsmd Inc Natural combination hormone replacement formulations and therapies
WO2013134503A2 (en) 2012-03-09 2013-09-12 Invisible Sentinel, Inc. Methods And Compositions For Detecting Multiple Analytes With A Single Signal
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
WO2015054546A1 (en) * 2013-10-10 2015-04-16 Song Diagnostic Research Llc. Improved lateral flow assays
WO2015061728A1 (en) * 2013-10-25 2015-04-30 Colorado State University Research Foundation Early determination of pregnancy status in ruminants
US20150044707A1 (en) * 2014-02-18 2015-02-12 Melinda Sanders At-Home Blood Pregnancy Test Kit
AR100562A1 (en) 2014-05-22 2016-10-12 Therapeuticsmd Inc PHARMACEUTICAL COMPOSITION OF ESTRADIOL AND PROGESTERONE FOR HORMONAL REPLACEMENT THERAPY
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
WO2017123599A1 (en) * 2016-01-11 2017-07-20 University Of Tennessee Research Foundation Pregnancy associated glycoprotein (pag) genes as markers of bull fertility
EP3405198B1 (en) * 2016-01-22 2021-08-04 Affimedix, Inc. Device for detection of vitamin d metabolites
WO2017173044A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Steroid hormone compositions in medium chain oils
CA3020153A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd, Inc. Steroid hormone pharmaceutical composition
KR102189893B1 (en) * 2017-11-15 2020-12-11 (주)에스엘에스바이오 Antibody specifically binding a bPAG1 and use thereof
CN108152515A (en) * 2017-12-26 2018-06-12 公安部南昌警犬基地 A kind of test paper detected for heat bitch progesterone and preparation method thereof
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations
WO2021203254A1 (en) * 2020-04-08 2021-10-14 杭州莱和生物技术有限公司 Test strip carrier plate, test device and manufacturing method therefor
WO2022026546A1 (en) * 2020-07-28 2022-02-03 Grindstone Diagnostics Llc Pregnancy detection tool and methods
WO2022039604A1 (en) * 2020-08-21 2022-02-24 Pictor Limited Multiplex assay for johne's disease and pregnancy

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2204398A (en) * 1987-04-27 1988-11-09 Unilever Plc Assays
US4877742A (en) * 1986-01-30 1989-10-31 Schering Aktiengesellschaft Pregnancy test with EPF
WO1999047934A2 (en) * 1998-03-20 1999-09-23 The Curators Of The University Of Missouri Early pregnancy diagnosis using pags (pregnancy-associated glycoproteins)
WO2000051520A2 (en) * 1999-03-02 2000-09-08 Kems Bio-Test Ltd. Bovine pregnancy testing
US20020192838A1 (en) * 2001-06-19 2002-12-19 Ott Troy L. Determination of pregnancy status

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL154598B (en) 1970-11-10 1977-09-15 Organon Nv PROCEDURE FOR DETERMINING AND DETERMINING LOW MOLECULAR COMPOUNDS AND PROTEINS THAT CAN SPECIFICALLY BIND THESE COMPOUNDS AND TEST PACKAGING.
US3817837A (en) 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3892855A (en) 1973-10-10 1975-07-01 Searle & Co Method for fertile breeding control in female bovine
US3939350A (en) 1974-04-29 1976-02-17 Board Of Trustees Of The Leland Stanford Junior University Fluorescent immunoassay employing total reflection for activation
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4275149A (en) 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
US4277437A (en) 1978-04-05 1981-07-07 Syva Company Kit for carrying out chemically induced fluorescence immunoassay
NL7807532A (en) 1978-07-13 1980-01-15 Akzo Nv METAL IMMUNO TEST.
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4486530A (en) 1980-08-04 1984-12-04 Hybritech Incorporated Immunometric assays using monoclonal antibodies
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US5073484A (en) 1982-03-09 1991-12-17 Bio-Metric Systems, Inc. Quantitative analysis apparatus and method
US4435504A (en) 1982-07-15 1984-03-06 Syva Company Immunochromatographic assay with support having bound "MIP" and second enzyme
US4518565A (en) * 1983-06-06 1985-05-21 Miles Laboratories, Inc. Reagent test device holder
US4705748A (en) 1983-07-21 1987-11-10 Idaho Research Foundation, Inc. Antigen associated with early detection of mammalian pregnancy
US4554256A (en) 1983-07-21 1985-11-19 The Idaho Research Foundation, Inc. Antigen associated with early detection of mammalian pregnancy
US4703017C1 (en) 1984-02-14 2001-12-04 Becton Dickinson Co Solid phase assay with visual readout
US4688621A (en) * 1984-03-28 1987-08-25 Falih Darmara Method and apparatus for casting rapidly solidified ingots
US4895804A (en) 1984-07-06 1990-01-23 University Of Minnesota Bovine antigen glycoprotein, related antibody, and use in detection of pregnancy in cattle
US4755460A (en) 1984-07-06 1988-07-05 The Regents Of The Univ. Of Minnesota Bovine antigen glycoprotein, related antibody, and use in detection of pregnancy in cattle
US4610687A (en) 1984-08-06 1986-09-09 Board Of Trustees Operating Michigan State University Method for breeding control in female bovines
US4740468A (en) 1985-02-14 1988-04-26 Syntex (U.S.A.) Inc. Concentrating immunochemical test device and method
US4668621A (en) 1985-04-22 1987-05-26 Wake Forest University Detecting blood clotting factors with immobilized fibrinogen and labeled fibrinogen
TW203120B (en) * 1985-10-04 1993-04-01 Abbott Lab
US5466585A (en) 1986-04-15 1995-11-14 Ciba-Geigy Corporation Interferon-induced human protein in pure form, monoclonal antibodies thereto, and test kits containing these antibodies
CA1303983C (en) 1987-03-27 1992-06-23 Robert W. Rosenstein Solid phase assay
US5137808A (en) 1987-04-07 1992-08-11 Syntex (U.S.A.) Inc. Immunoassay device
US5360895A (en) 1987-04-22 1994-11-01 Associated Universities, Inc. Derivatized gold clusters and antibody-gold cluster conjugates
US4855240A (en) 1987-05-13 1989-08-08 Becton Dickinson And Company Solid phase assay employing capillary flow
US4954452A (en) 1987-07-09 1990-09-04 Abbott Laboratories Non-metal colloidal particle immunoassay
US5028535A (en) 1989-01-10 1991-07-02 Biosite Diagnostics, Inc. Threshold ligand-receptor assay
US6352862B1 (en) 1989-02-17 2002-03-05 Unilever Patent Holdings B.V. Analytical test device for imuno assays and methods of using same
GB8903627D0 (en) 1989-02-17 1989-04-05 Unilever Plc Assays
US5075078A (en) 1989-10-05 1991-12-24 Abbott Laboratories Self-performing immunochromatographic device
US5595707A (en) 1990-03-02 1997-01-21 Ventana Medical Systems, Inc. Automated biological reaction apparatus
US5607863A (en) 1991-05-29 1997-03-04 Smithkline Diagnostics, Inc. Barrier-controlled assay device
US5229073A (en) 1992-02-27 1993-07-20 Abbott Laboratories One-step competitive immunoassay for the semiquantitative determination of plasma lipoprotein(a)
US5840524A (en) 1992-11-27 1998-11-24 Stichting Rega Vzw Granulocyte chemotactic protein
US6180102B1 (en) 1994-08-08 2001-01-30 Kyowa Hakko Kogyo Co., Ltd. Monoclonal antibody to human Mx protein MxA
ATE230418T1 (en) 1994-08-08 2003-01-15 Kyowa Hakko Kogyo Kk MONOCLONAL ANTIBODIES AGAINST THE HUMAN MX PROTEIN MXA
US5589457A (en) 1995-07-03 1996-12-31 Ausa International, Inc. Process for the synchronization of ovulation
US6406922B2 (en) * 1996-03-11 2002-06-18 American Bio Medica Corp. Device for the testing of body fluid samples
US5798273A (en) 1996-09-25 1998-08-25 Becton Dickinson And Company Direct read lateral flow assay for small analytes
US6924153B1 (en) * 1997-03-06 2005-08-02 Quidel Corporation Quantitative lateral flow assays and devices
US6248598B1 (en) * 1998-09-17 2001-06-19 Stuart C. Bogema Immunoassay that provides for both collection of saliva and assay of saliva for one or more analytes with visual readout
EP1237555A2 (en) 1999-12-16 2002-09-11 PHARMACIA & UPJOHN COMPANY Implant composition containing melengestrol acetate and trenbolone acetate
AU2001269707A1 (en) 2000-07-10 2002-01-21 Pharmacia And Upjohn Company Method for improving the efficacy of artificial insemination of non-human animals
US20030143601A1 (en) 2001-11-16 2003-07-31 Hansen Thomas R. Methods and compositions for the detection of bovine pregnancy which utilize members of the 1-8 family of interferon inducible genes
AU2002366097B2 (en) * 2001-11-20 2008-09-18 Monsanto Technology Llc Compositions and methods for accurate early pregnancy diagnosis

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4877742A (en) * 1986-01-30 1989-10-31 Schering Aktiengesellschaft Pregnancy test with EPF
GB2204398A (en) * 1987-04-27 1988-11-09 Unilever Plc Assays
WO1999047934A2 (en) * 1998-03-20 1999-09-23 The Curators Of The University Of Missouri Early pregnancy diagnosis using pags (pregnancy-associated glycoproteins)
WO2000051520A2 (en) * 1999-03-02 2000-09-08 Kems Bio-Test Ltd. Bovine pregnancy testing
US20020192838A1 (en) * 2001-06-19 2002-12-19 Ott Troy L. Determination of pregnancy status

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
OTT ET AL.: "Effects of the estrous cycle and early pregnancy on uterine expression of Mx protein in sheep (ovis aries)", BIOLOGY OF REPRODUCTION, vol. 59, 1998, pages 784 - 794, XP002962277 *
XIE ET AL.: "Identification of the major pregnancy-specific antigens of cattle and sheep as inactive members of the aspartic proteinase family", PROC. NATL. ACAD. SCI., vol. 88, November 1991 (1991-11-01), pages 10247 - 10251, XP002109213 *
YANKEY ET AL.: "Expression of the antiviral protein Mx in peripheral blood mononuclear cells of pregnant and brad, non-pregnant ewes", JOURNAL OF ENDOCRINOLOGY, vol. 170, 2001, pages R7 - R11, XP002962276 *

Also Published As

Publication number Publication date
US7687281B2 (en) 2010-03-30
US20070184558A1 (en) 2007-08-09
US7393696B2 (en) 2008-07-01
US20030073248A1 (en) 2003-04-17
AU2002330102A1 (en) 2003-04-14
WO2003028582A2 (en) 2003-04-10

Similar Documents

Publication Publication Date Title
WO2003028582A3 (en) Bovine pregnancy test
WO2000000610A3 (en) Human signal peptide-containing proteins
WO1999061471A3 (en) Human transmembrane proteins
ATE464374T1 (en) ASSAY FOR THE RAPID DETECTION OF HUMAN ACTIVATED PROTEIN C AND HIGHLY SPECIFIC MONOCLONAL ANTIBODIES AGAINST IT
ATE430939T1 (en) PREGNANCY DETECTION METHOD
WO2002067760A3 (en) Methods for treating autoimmune diseases in a subject and in vitro diagnostic assays
EP1459624A3 (en) Automatic system-based animal training device
DE69520108D1 (en) TEST PROCEDURE
ITMI982496A1 (en) PROCEDURE FOR TESTING AN AUTOMATED CLUTCH DEVICE, IN PARTICULAR OF A CLUTCH DEVICE ARRANGED IN THE
CA2008304A1 (en) Assay for bone alkaline phosphatase
WO2001005970A3 (en) Gtp-binding protein associated factors
WO2001007612A3 (en) Receptors and associated proteins
WO2000052151A3 (en) Human secretory proteins
WO2000078953A3 (en) Human transport proteins
WO2000031263A3 (en) Gtpase associated proteins
WO2000003015A3 (en) Human transport protein homologs
WO1999001085A3 (en) Autoimmune inner ear disease antigen and diagnostic assay
NZ518260A (en) Assays for mastitis using antibodies to detect haptoglobin in milk
IL108811A0 (en) Immunoassay reagents, kits and methods
WO2001083524A3 (en) Rna metabolism proteins
WO2002016431A3 (en) PEPTIDES OF THE α1-ADRENERGIC RECEPTOR AND THEIR USE FOR PSORIASIS
WO1998057986A3 (en) Human preprotachykinin b
WO2001046256A3 (en) Vesicle trafficking proteins
WO1998041538A3 (en) Novel human cytokine/steroid receptor protein
WO2000026243A3 (en) Transmembrane 4 proteins

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BY BZ CA CH CN CO CR CU CZ DE DM DZ EC EE ES FI GB GD GE GH HR HU ID IL IN IS JP KE KG KP KR LC LK LR LS LT LU LV MA MD MG MN MW MX MZ NO NZ OM PH PL PT RU SD SE SG SI SK SL TJ TM TN TR TZ UA UG UZ VC VN YU ZA ZM

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ UG ZM ZW AM AZ BY KG KZ RU TJ TM AT BE BG CH CY CZ DK EE ES FI FR GB GR IE IT LU MC PT SE SK TR BF BJ CF CG CI GA GN GQ GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP

WWW Wipo information: withdrawn in national office

Country of ref document: JP

DPE2 Request for preliminary examination filed before expiration of 19th month from priority date (pct application filed from 20040101)