WO2003042403A3 - Biochips for characterizing biological processes - Google Patents

Biochips for characterizing biological processes Download PDF

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Publication number
WO2003042403A3
WO2003042403A3 PCT/US2002/036630 US0236630W WO03042403A3 WO 2003042403 A3 WO2003042403 A3 WO 2003042403A3 US 0236630 W US0236630 W US 0236630W WO 03042403 A3 WO03042403 A3 WO 03042403A3
Authority
WO
WIPO (PCT)
Prior art keywords
biochips
biological processes
characterizing biological
raman
analyte
Prior art date
Application number
PCT/US2002/036630
Other languages
French (fr)
Other versions
WO2003042403A2 (en
Inventor
David I Kreimer
Thomas H Nufert
Lev Ginzburg
Oleg A Yevin
Original Assignee
Array Bioscience Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Array Bioscience Corp filed Critical Array Bioscience Corp
Priority to AU2002360390A priority Critical patent/AU2002360390A1/en
Publication of WO2003042403A2 publication Critical patent/WO2003042403A2/en
Publication of WO2003042403A3 publication Critical patent/WO2003042403A3/en

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips

Abstract

This invention includes biochips (Figure 18d) for analysis of a variety of molecules, cell components and cells. Embodiments of this invention include devices and methods for parallel and/or nearly parallel processing of biological analytes. Biochips can comprise a substrate, Raman signal-enhancing structures, and receptors selective and/or specific for the analyte(s) to be assayed. Biochips can be read using a Raman reader and can provide for rapid, sensitive, direct assays for physiological and/or pathophysiological conditions of interest.
PCT/US2002/036630 2001-11-14 2002-11-14 Biochips for characterizing biological processes WO2003042403A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002360390A AU2002360390A1 (en) 2001-11-14 2002-11-14 Biochips for characterizing biological processes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US33644501P 2001-11-14 2001-11-14
US60/336,445 2001-11-14

Publications (2)

Publication Number Publication Date
WO2003042403A2 WO2003042403A2 (en) 2003-05-22
WO2003042403A3 true WO2003042403A3 (en) 2004-01-29

Family

ID=23316119

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/036630 WO2003042403A2 (en) 2001-11-14 2002-11-14 Biochips for characterizing biological processes

Country Status (2)

Country Link
AU (1) AU2002360390A1 (en)
WO (1) WO2003042403A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009052376A1 (en) 2007-10-18 2009-04-23 Musc Foundation For Research Development Methods for the diagnosis of genitourinary cancer
CN108444978B (en) * 2018-06-08 2020-09-18 南京师范大学 Detection method of heme based on surface enhanced Raman spectroscopy of dendritic gold nanostructure and application of heme
CN108444979B (en) * 2018-06-08 2020-10-02 南京师范大学 Method for detecting hemin in erythrocyte based on surface enhanced Raman spectroscopy and application thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5567628A (en) * 1989-10-27 1996-10-22 Abbott Laboratories Surface-enhanced raman spectroscopy immunoassay method, composition and kit
US6174677B1 (en) * 1995-10-13 2001-01-16 Ut-Battelle, Llc Advanced surface-enhanced Raman gene probe systems and methods thereof
US20020132371A1 (en) * 1999-09-27 2002-09-19 Kreimer David I. Amplification of analyte detection by substrates having particle structures with receptors
WO2002074899A1 (en) * 2001-03-15 2002-09-26 Array Bioscience Corporation Enhancing surfaces for analyte detection
WO2002077647A1 (en) * 2001-03-23 2002-10-03 Array Bioscience Corporation Amplification of analyte detection by substrates having particle structures with receptors

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5567628A (en) * 1989-10-27 1996-10-22 Abbott Laboratories Surface-enhanced raman spectroscopy immunoassay method, composition and kit
US6174677B1 (en) * 1995-10-13 2001-01-16 Ut-Battelle, Llc Advanced surface-enhanced Raman gene probe systems and methods thereof
US20020132371A1 (en) * 1999-09-27 2002-09-19 Kreimer David I. Amplification of analyte detection by substrates having particle structures with receptors
WO2002074899A1 (en) * 2001-03-15 2002-09-26 Array Bioscience Corporation Enhancing surfaces for analyte detection
US20020151041A1 (en) * 2001-03-15 2002-10-17 Kreimer David I. Enhancing surfaces for analyte detection
WO2002077647A1 (en) * 2001-03-23 2002-10-03 Array Bioscience Corporation Amplification of analyte detection by substrates having particle structures with receptors

Also Published As

Publication number Publication date
AU2002360390A1 (en) 2003-05-26
WO2003042403A2 (en) 2003-05-22

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