WO2003048334A3 - Immunocytokines with modulated selectivity - Google Patents
Immunocytokines with modulated selectivity Download PDFInfo
- Publication number
- WO2003048334A3 WO2003048334A3 PCT/US2002/038780 US0238780W WO03048334A3 WO 2003048334 A3 WO2003048334 A3 WO 2003048334A3 US 0238780 W US0238780 W US 0238780W WO 03048334 A3 WO03048334 A3 WO 03048334A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- fusion proteins
- immunocytokines
- cytokine
- bind
- therapeutic index
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/54—Interleukins [IL]
- C07K14/55—IL-2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
- G01N33/567—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds utilising isolate of tissue or organ as binding agent
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Abstract
Priority Applications (11)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK02792325.9T DK1454138T3 (en) | 2001-12-04 | 2002-12-04 | Immunocytokines with modulated selectivity |
BR0214650-9A BR0214650A (en) | 2001-12-04 | 2002-12-04 | Modulated selectivity immunocytokines |
AU2002357784A AU2002357784B2 (en) | 2001-12-04 | 2002-12-04 | Immunocytokines with modulated selectivity |
JP2003549513A JP4795640B2 (en) | 2001-12-04 | 2002-12-04 | Immune cytokines with regulated selectivity |
CA2469151A CA2469151C (en) | 2001-12-04 | 2002-12-04 | Immunocytokines with modulated selectivity |
EP02792325A EP1454138B1 (en) | 2001-12-04 | 2002-12-04 | Immunocytokines with modulated selectivity |
ES02792325T ES2381025T3 (en) | 2001-12-04 | 2002-12-04 | Immunocytokines with modulated selectivity |
AT02792325T ATE542137T1 (en) | 2001-12-04 | 2002-12-04 | IMMUNOCYTOKINE WITH MODULATED SELECTIVITY |
HU0402541A HU229098B1 (en) | 2001-12-04 | 2002-12-04 | Immunocytokines with modulated selectivity |
MXPA04005266A MXPA04005266A (en) | 2001-12-04 | 2002-12-04 | Immunocytokines with modulated selectivity. |
ZA2004/05247A ZA200405247B (en) | 2001-12-04 | 2004-07-01 | Immunocytokines with modulated selectivity |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US33711301P | 2001-12-04 | 2001-12-04 | |
US60/337,113 | 2001-12-04 | ||
US37196602P | 2002-04-12 | 2002-04-12 | |
US60/371,966 | 2002-04-12 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2003048334A2 WO2003048334A2 (en) | 2003-06-12 |
WO2003048334A3 true WO2003048334A3 (en) | 2003-09-04 |
Family
ID=26990541
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2002/038780 WO2003048334A2 (en) | 2001-12-04 | 2002-12-04 | Immunocytokines with modulated selectivity |
Country Status (18)
Country | Link |
---|---|
US (3) | US7186804B2 (en) |
EP (2) | EP1454138B1 (en) |
JP (1) | JP4795640B2 (en) |
KR (1) | KR100988180B1 (en) |
CN (1) | CN100390282C (en) |
AT (1) | ATE542137T1 (en) |
AU (1) | AU2002357784B2 (en) |
BR (1) | BR0214650A (en) |
CA (1) | CA2469151C (en) |
DK (1) | DK1454138T3 (en) |
ES (1) | ES2381025T3 (en) |
HU (1) | HU229098B1 (en) |
MX (1) | MXPA04005266A (en) |
PL (1) | PL206975B1 (en) |
PT (1) | PT1454138E (en) |
RU (1) | RU2312677C9 (en) |
WO (1) | WO2003048334A2 (en) |
ZA (1) | ZA200405247B (en) |
Cited By (3)
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US8907066B2 (en) | 2009-04-22 | 2014-12-09 | Merck Patent Gmbh | Antibody fusion proteins with a modified FcRn binding site |
US11851471B2 (en) | 2017-01-09 | 2023-12-26 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
US11851467B2 (en) | 2016-12-22 | 2023-12-26 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
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ES2288967T3 (en) * | 2000-06-29 | 2008-02-01 | Merck Patent Gmbh | REINFORCEMENT OF IMMUNE ANSWERS MEDIATED BY THE ANTIBODY-CYTOKIN FUSION PROTEIN THROUGH THE TREATMENT COMBINED BY AGENTS THAT IMPROVE THE INCORPORATION OF IMMUNOCITOQUINE. |
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US11851467B2 (en) | 2016-12-22 | 2023-12-26 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
US11851471B2 (en) | 2017-01-09 | 2023-12-26 | Cue Biopharma, Inc. | T-cell modulatory multimeric polypeptides and methods of use thereof |
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