WO2003057914A3 - METHOD FOR DETECTING HUMAN PAPILLOMAVIRUS mRNA - Google Patents

METHOD FOR DETECTING HUMAN PAPILLOMAVIRUS mRNA Download PDF

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Publication number
WO2003057914A3
WO2003057914A3 PCT/GB2003/000034 GB0300034W WO03057914A3 WO 2003057914 A3 WO2003057914 A3 WO 2003057914A3 GB 0300034 W GB0300034 W GB 0300034W WO 03057914 A3 WO03057914 A3 WO 03057914A3
Authority
WO
WIPO (PCT)
Prior art keywords
human papillomavirus
mrna
detecting human
risk
expression
Prior art date
Application number
PCT/GB2003/000034
Other languages
French (fr)
Other versions
WO2003057914A2 (en
Inventor
Frank Karlsen
Original Assignee
Norchip As
Frank Karlsen
Allard Susan Joyce
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26246916&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2003057914(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB0200239A external-priority patent/GB0200239D0/en
Priority claimed from GB0214124A external-priority patent/GB0214124D0/en
Priority to AU2003201639A priority Critical patent/AU2003201639C1/en
Priority to MXPA04006440A priority patent/MXPA04006440A/en
Priority to JP2003558207A priority patent/JP4558322B2/en
Priority to IL16272203A priority patent/IL162722A0/en
Priority to CA002472026A priority patent/CA2472026A1/en
Priority to NZ533703A priority patent/NZ533703A/en
Priority to US10/500,832 priority patent/US7553623B2/en
Priority to SI200330775T priority patent/SI1463839T1/en
Priority to DK03700338T priority patent/DK1463839T3/en
Application filed by Norchip As, Frank Karlsen, Allard Susan Joyce filed Critical Norchip As
Priority to DE60311961T priority patent/DE60311961T2/en
Priority to BR0306723-8A priority patent/BR0306723A/en
Priority to EP03700338A priority patent/EP1463839B1/en
Priority to EA200400919A priority patent/EA006975B1/en
Publication of WO2003057914A2 publication Critical patent/WO2003057914A2/en
Publication of WO2003057914A3 publication Critical patent/WO2003057914A3/en
Priority to IL162722A priority patent/IL162722A/en
Priority to NO20042769A priority patent/NO20042769L/en
Priority to HK04108678A priority patent/HK1065827A1/en
Priority to CY20071100705T priority patent/CY1106621T1/en
Priority to AU2008205436A priority patent/AU2008205436A1/en
Priority to US12/483,900 priority patent/US7812144B2/en
Priority to US12/483,860 priority patent/US8420314B2/en
Priority to US13/792,414 priority patent/US20130309658A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/708—Specific hybridization probes for papilloma
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Abstract

An in vitro method is provided for screening human female subjects to assess their risk of developing cervical carcinoma which comprises screening the subject for expression of mRNA transcripts from the E6 and optionally the L1 gene of human papillomavirus, wherein subjects positive for expression of L1 and/or E6 mRNA are scored as being at risk of developing cervical carcinoma. Kits for carrying out such methods are also provided.
PCT/GB2003/000034 2002-01-07 2003-01-07 METHOD FOR DETECTING HUMAN PAPILLOMAVIRUS mRNA WO2003057914A2 (en)

Priority Applications (21)

Application Number Priority Date Filing Date Title
EP03700338A EP1463839B1 (en) 2002-01-07 2003-01-07 Method for detecting human papillomavirus mrna
EA200400919A EA006975B1 (en) 2002-01-07 2003-01-07 METHOD FOR DETECTING HUMAN PAPILLOMAVIRUS mRNA
SI200330775T SI1463839T1 (en) 2002-01-07 2003-01-07 Method for detecting human papillomavirus mrna
BR0306723-8A BR0306723A (en) 2002-01-07 2003-01-07 In vitro methods for selecting human subjects to assess their risk of developing cervical carcinoma, and for selecting human subjects for the presence of integrated hpv or a modified episomal hpv genome, in vitro method for identifying human subjects presenting abnormal cell changes in the cervix, and kit for use in detecting mpna transcripts of hpv l1 and e6 genes
JP2003558207A JP4558322B2 (en) 2002-01-07 2003-01-07 Method for detecting human papillomavirus mRNA
IL16272203A IL162722A0 (en) 2002-01-07 2003-01-07 Method for detecting human papillomarirus mrna
CA002472026A CA2472026A1 (en) 2002-01-07 2003-01-07 Method for detecting human papillomavirus mrna
NZ533703A NZ533703A (en) 2002-01-07 2003-01-07 Method for detecting human papillomavirus mRNA
US10/500,832 US7553623B2 (en) 2002-01-07 2003-01-07 Method for detecting human papillomavirus mRNA
MXPA04006440A MXPA04006440A (en) 2002-01-07 2003-01-07 Method for detecting human papillomarvirus mrna.
DK03700338T DK1463839T3 (en) 2002-01-07 2003-01-07 Method for detecting human papillomavirus mRNA
AU2003201639A AU2003201639C1 (en) 2002-01-07 2003-01-07 Method for detecting human papillomavirus mRNA
DE60311961T DE60311961T2 (en) 2002-01-07 2003-01-07 DETECTION PROCEDURE FOR PAPILLOMA VIRUS MRNA
IL162722A IL162722A (en) 2002-01-07 2004-06-24 In vitro method of identifying abnormal cervical cell changes in humans and kit therefor
NO20042769A NO20042769L (en) 2002-01-07 2004-06-30 Method of showing human papillomavirus mRNA
HK04108678A HK1065827A1 (en) 2002-01-07 2004-11-04 Method for detecting human papillomarvirus mrna
CY20071100705T CY1106621T1 (en) 2002-01-07 2007-05-21 METHOD FOR THE DETECTION OF HUMAN PAMMIO VIRUS mRNA
AU2008205436A AU2008205436A1 (en) 2002-01-07 2008-08-14 Method for detecting human papillomavirus mRNA
US12/483,860 US8420314B2 (en) 2002-01-07 2009-06-12 Method for detecting human papillomavirus mRNA
US12/483,900 US7812144B2 (en) 2002-01-07 2009-06-12 Method for detecting human papillomavirus mRNA
US13/792,414 US20130309658A1 (en) 2002-01-07 2013-03-11 METHOD FOR DETECTING HUMAN PAPILLOMAVIRUS mRNA

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0200239.2 2002-01-07
GB0200239A GB0200239D0 (en) 2002-01-07 2002-01-07 Method for detecting human papillomavirus mRNA
GB0214124A GB0214124D0 (en) 2002-06-19 2002-06-19 Method for detecting human papillomavirus mRNA
GB0214124.0 2002-06-19

Related Child Applications (3)

Application Number Title Priority Date Filing Date
US10500832 A-371-Of-International 2003-01-07
US12/483,900 Division US7812144B2 (en) 2002-01-07 2009-06-12 Method for detecting human papillomavirus mRNA
US12/483,860 Continuation US8420314B2 (en) 2002-01-07 2009-06-12 Method for detecting human papillomavirus mRNA

Publications (2)

Publication Number Publication Date
WO2003057914A2 WO2003057914A2 (en) 2003-07-17
WO2003057914A3 true WO2003057914A3 (en) 2004-02-26

Family

ID=26246916

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2003/000034 WO2003057914A2 (en) 2002-01-07 2003-01-07 METHOD FOR DETECTING HUMAN PAPILLOMAVIRUS mRNA

Country Status (21)

Country Link
US (4) US7553623B2 (en)
EP (5) EP1715062B1 (en)
JP (2) JP4558322B2 (en)
CN (1) CN100422342C (en)
AT (1) ATE354677T1 (en)
AU (2) AU2003201639C1 (en)
BR (1) BR0306723A (en)
CA (1) CA2472026A1 (en)
CY (1) CY1106621T1 (en)
DE (1) DE60311961T2 (en)
DK (2) DK2913407T3 (en)
EA (1) EA006975B1 (en)
ES (2) ES2654909T3 (en)
HK (1) HK1065827A1 (en)
IL (2) IL162722A0 (en)
MX (1) MXPA04006440A (en)
NO (1) NO20042769L (en)
NZ (1) NZ533703A (en)
PT (1) PT1463839E (en)
SI (1) SI1463839T1 (en)
WO (1) WO2003057914A2 (en)

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