WO2003059880A1 - Derive d'amino-alcool ou derive d'acide phosphonique et composition medicamenteuse les contenant - Google Patents

Derive d'amino-alcool ou derive d'acide phosphonique et composition medicamenteuse les contenant Download PDF

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Publication number
WO2003059880A1
WO2003059880A1 PCT/JP2003/000136 JP0300136W WO03059880A1 WO 2003059880 A1 WO2003059880 A1 WO 2003059880A1 JP 0300136 W JP0300136 W JP 0300136W WO 03059880 A1 WO03059880 A1 WO 03059880A1
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WO
WIPO (PCT)
Prior art keywords
derivative
composition containing
phosphonic acid
medicinal composition
amino alcohol
Prior art date
Application number
PCT/JP2003/000136
Other languages
English (en)
French (fr)
Inventor
Takahide Nishi
Takaichi Shimozato
Futoshi Nara
Shojiro Miyazaki
Original Assignee
Sankyo Company, Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to AT03701048T priority Critical patent/ATE435202T1/de
Priority to BR0306811-0A priority patent/BR0306811A/pt
Priority to IL16287403A priority patent/IL162874A0/xx
Priority to DE60328161T priority patent/DE60328161D1/de
Priority to DK03701048T priority patent/DK1471054T3/da
Priority to MXPA04006709A priority patent/MXPA04006709A/es
Priority to NZ533994A priority patent/NZ533994A/xx
Priority to EP03701048A priority patent/EP1471054B1/en
Priority to KR1020047010719A priority patent/KR100836547B1/ko
Priority to CA2473461A priority patent/CA2473461C/en
Application filed by Sankyo Company, Limited filed Critical Sankyo Company, Limited
Priority to AU2003202495A priority patent/AU2003202495B2/en
Priority to SI200331668T priority patent/SI1471054T1/sl
Publication of WO2003059880A1 publication Critical patent/WO2003059880A1/ja
Priority to US10/889,657 priority patent/US7199150B2/en
Priority to ZA2004/06333A priority patent/ZA200406333B/en
Priority to NO20043319A priority patent/NO329134B1/no
Priority to HK04109418.1A priority patent/HK1066532A1/xx
Priority to US11/636,776 priority patent/US20070105933A1/en
Priority to US11/651,205 priority patent/US7638551B2/en
Priority to US12/460,884 priority patent/US8067396B2/en
Priority to US12/583,001 priority patent/US8101650B2/en

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    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
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    • C—CHEMISTRY; METALLURGY
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/572—Five-membered rings
    • C—CHEMISTRY; METALLURGY
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    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
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    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms
    • C07F9/655345—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a five-membered ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
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PCT/JP2003/000136 2002-01-11 2003-01-09 Derive d'amino-alcool ou derive d'acide phosphonique et composition medicamenteuse les contenant WO2003059880A1 (fr)

Priority Applications (20)

Application Number Priority Date Filing Date Title
AU2003202495A AU2003202495B2 (en) 2002-01-11 2003-01-09 Amino alcohol derivative or phosphonic acid derivative and medicinal composition containing these
BR0306811-0A BR0306811A (pt) 2002-01-11 2003-01-09 Composto, éster farmacologicamente aceitável do mesmo, composição farmacêutica e métodos para prevenção ou tratamento de doenças autoimunes, da artrite reumatóide e da rejeição causada pelo transplante de vários órgãos em um mamìfero
DE60328161T DE60328161D1 (de) 2002-01-11 2003-01-09 Aminoalkoholderivat oder phosphonsäurederivat und diese enthaltende medizinische zusammensetzung
DK03701048T DK1471054T3 (da) 2002-01-11 2003-01-09 Aminoalkohol-derivat eller phosphonsyre-derivat og medicinsk sammensætning, der indeholder disse
MXPA04006709A MXPA04006709A (es) 2002-01-11 2003-01-09 Derivados de aminoalcohol o derivados de acido fosfonico y composiciones farmaceuticas que los contienen.
NZ533994A NZ533994A (en) 2002-01-11 2003-01-09 Amino alcohol derivative or phosphonic acid derivative and medicinal compostion containing these
EP03701048A EP1471054B1 (en) 2002-01-11 2003-01-09 Amino alcohol derivative or phosphonic acid derivative and medicinal composition containing these
SI200331668T SI1471054T1 (sl) 2002-01-11 2003-01-09 Amino alkoholni derivati ali derivati fosfoniäśne kisline in medicinski sestavki, ki vsebujejo le-te
CA2473461A CA2473461C (en) 2002-01-11 2003-01-09 Amino alcohol derivative or phosphonic acid derivative and medicinal composition containing these
AT03701048T ATE435202T1 (de) 2002-01-11 2003-01-09 Aminoalkoholderivat oder phosphonsäurederivat und diese enthaltende medizinische zusammensetzung
IL16287403A IL162874A0 (en) 2002-01-11 2003-01-09 Amino alcohol and phosphonic acid derivatives and pharmaceutical compositions containing the same
KR1020047010719A KR100836547B1 (ko) 2002-01-11 2003-01-09 아미노 알코올 유도체 또는 포스폰산 유도체 및 이들을함유하는 의약 조성물
US10/889,657 US7199150B2 (en) 2002-01-11 2004-07-12 Amino alcohol compounds
ZA2004/06333A ZA200406333B (en) 2002-01-11 2004-08-10 Amino alcohol derivative or phosphonic acid derivative and medicinal composition containing these
NO20043319A NO329134B1 (no) 2002-01-11 2004-08-10 Aminoalkoholderivater eller fosfonsyrederivater og farmasoytiske preparater som inneholder disse og som kan anvendes ved profylakse eller behandling av autoimmunsykdommer
HK04109418.1A HK1066532A1 (en) 2002-01-11 2004-11-30 Amino alcohol derivative or phosphonic acid derivative and medicinal composition containing these
US11/636,776 US20070105933A1 (en) 2002-01-11 2006-12-11 Amino alcohol compounds
US11/651,205 US7638551B2 (en) 2002-01-11 2007-01-09 Amino alcohol compounds or phosphonic acid derivatives thereof
US12/460,884 US8067396B2 (en) 2002-01-11 2009-07-24 Amino alcohol compounds or phosphonic acid derivatives thereof
US12/583,001 US8101650B2 (en) 2002-01-11 2009-08-12 Method for treating a immunology-related disease

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP2002-004456 2002-01-11
JP2002004484 2002-01-11
JP2002-004484 2002-01-11
JP2002004456 2002-01-11

Related Child Applications (1)

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US10/889,657 Continuation-In-Part US7199150B2 (en) 2002-01-11 2004-07-12 Amino alcohol compounds

Publications (1)

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WO2003059880A1 true WO2003059880A1 (fr) 2003-07-24

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PCT/JP2003/000136 WO2003059880A1 (fr) 2002-01-11 2003-01-09 Derive d'amino-alcool ou derive d'acide phosphonique et composition medicamenteuse les contenant

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JP2003267950A (ja) 2003-09-25
NO329134B1 (no) 2010-08-30
CY1109457T1 (el) 2014-08-13
CO5640126A2 (es) 2006-05-31
CN1630635A (zh) 2005-06-22
CA2473461C (en) 2011-11-01
RU2004121143A (ru) 2006-02-27
KR100836547B1 (ko) 2008-06-10
KR20080035702A (ko) 2008-04-23
JP4270541B2 (ja) 2009-06-03
EP1471054B1 (en) 2009-07-01
EP1471054A4 (en) 2005-06-08
CN100406437C (zh) 2008-07-30
ES2327825T3 (es) 2009-11-04
BR0306811A (pt) 2004-10-26
PL211954B1 (pl) 2012-07-31
HK1066532A1 (en) 2005-03-24
AU2003202495B2 (en) 2006-07-20
MXPA04006709A (es) 2004-10-04
DE60328161D1 (de) 2009-08-13
ZA200406333B (en) 2005-12-28
US8067396B2 (en) 2011-11-29
RU2330839C2 (ru) 2008-08-10
EP1471054A1 (en) 2004-10-27
TW200302087A (en) 2003-08-01
US7199150B2 (en) 2007-04-03
US8101650B2 (en) 2012-01-24
US20090326038A1 (en) 2009-12-31
ATE435202T1 (de) 2009-07-15
SI1471054T1 (sl) 2009-12-31
KR20040075068A (ko) 2004-08-26
DK1471054T3 (da) 2009-11-09
NO20043319L (no) 2004-10-05
PL370790A1 (en) 2005-05-30
US7638551B2 (en) 2009-12-29
AU2003202495A1 (en) 2003-07-30
NZ533994A (en) 2006-10-27
TWI283574B (en) 2007-07-11
US20100035842A1 (en) 2010-02-11
US20070105933A1 (en) 2007-05-10
US20070142335A1 (en) 2007-06-21
IL162874A0 (en) 2005-11-20
US20050043386A1 (en) 2005-02-24
CA2473461A1 (en) 2003-07-24

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