WO2003060154A3 - Method and apparatus for processing electrochemical signals - Google Patents

Method and apparatus for processing electrochemical signals Download PDF

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Publication number
WO2003060154A3
WO2003060154A3 PCT/US2003/001113 US0301113W WO03060154A3 WO 2003060154 A3 WO2003060154 A3 WO 2003060154A3 US 0301113 W US0301113 W US 0301113W WO 03060154 A3 WO03060154 A3 WO 03060154A3
Authority
WO
WIPO (PCT)
Prior art keywords
analyte
signal
select
vector
current signal
Prior art date
Application number
PCT/US2003/001113
Other languages
French (fr)
Other versions
WO2003060154A2 (en
Inventor
Sridhar G Iyengar
Daniel Haas
Craig Bolon
Original Assignee
Agamatrix Inc
Sridhar G Iyengar
Daniel Haas
Craig Bolon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agamatrix Inc, Sridhar G Iyengar, Daniel Haas, Craig Bolon filed Critical Agamatrix Inc
Priority to MXPA04006783A priority Critical patent/MXPA04006783A/en
Priority to CA002472584A priority patent/CA2472584A1/en
Priority to KR10-2004-7010950A priority patent/KR20040077722A/en
Priority to AU2003203004A priority patent/AU2003203004B2/en
Priority to JP2003560236A priority patent/JP2005515413A/en
Priority to EP03702120A priority patent/EP1466008A2/en
Publication of WO2003060154A2 publication Critical patent/WO2003060154A2/en
Publication of WO2003060154A3 publication Critical patent/WO2003060154A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements
    • G01N27/3271—Amperometric enzyme electrodes for analytes in body fluids, e.g. glucose in blood
    • G01N27/3274—Corrective measures, e.g. error detection, compensation for temperature or hematocrit, calibration
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/54—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis

Abstract

Systems and methods are provided herein for improving the selectivity and productivity of sensors via digital signal processing techniques. According to one illustrative embodiment, in an electrochemical method for monitoring of a select analyte in a mixed sample with an interfering analyte, an improvement is provided that includes applying a large amplitude potential stimulus waveform to the sample to generate a nonlinear current signal; and resolving a signal contribution from the select analyte in the generated signal by a vector projection method with an analyte vector comprising a plurality of real and imaginary parts of one or more Fourier coefficients at one or more frequencies of a reference current signal for the select analyte.
PCT/US2003/001113 2002-01-15 2003-01-15 Method and apparatus for processing electrochemical signals WO2003060154A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
MXPA04006783A MXPA04006783A (en) 2002-01-15 2003-01-15 Method and apparatus for processing electrochemical signals.
CA002472584A CA2472584A1 (en) 2002-01-15 2003-01-15 Method and apparatus for processing electrochemical signals
KR10-2004-7010950A KR20040077722A (en) 2002-01-15 2003-01-15 Method and apparatus for processing electrochemical signals
AU2003203004A AU2003203004B2 (en) 2002-01-15 2003-01-15 Method and apparatus for processing electrochemical signals
JP2003560236A JP2005515413A (en) 2002-01-15 2003-01-15 Electrochemical signal processing method and apparatus
EP03702120A EP1466008A2 (en) 2002-01-15 2003-01-15 Method and apparatus for processing electrochemical signals

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35017502P 2002-01-15 2002-01-15
US60/350,175 2002-01-15

Publications (2)

Publication Number Publication Date
WO2003060154A2 WO2003060154A2 (en) 2003-07-24
WO2003060154A3 true WO2003060154A3 (en) 2004-08-05

Family

ID=23375524

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2003/001113 WO2003060154A2 (en) 2002-01-15 2003-01-15 Method and apparatus for processing electrochemical signals

Country Status (9)

Country Link
US (3) US7090764B2 (en)
EP (1) EP1466008A2 (en)
JP (1) JP2005515413A (en)
KR (1) KR20040077722A (en)
CN (1) CN1615434A (en)
AU (1) AU2003203004B2 (en)
CA (1) CA2472584A1 (en)
MX (1) MXPA04006783A (en)
WO (1) WO2003060154A2 (en)

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