WO2003072757A3 - Nucleotide mimics and their prodrugs - Google Patents
Nucleotide mimics and their prodrugs Download PDFInfo
- Publication number
- WO2003072757A3 WO2003072757A3 PCT/US2003/006368 US0306368W WO03072757A3 WO 2003072757 A3 WO2003072757 A3 WO 2003072757A3 US 0306368 W US0306368 W US 0306368W WO 03072757 A3 WO03072757 A3 WO 03072757A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- present
- mimics
- disphosphate
- modifications
- pharmaceutically acceptable
- Prior art date
Links
- 0 CC(*)(**1)C(C)(*)C1(*)C(*)* Chemical compound CC(*)(**1)C(C)(*)C1(*)C(*)* 0.000 description 9
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/14—Pyrrolo-pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
Abstract
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002477741A CA2477741A1 (en) | 2002-02-28 | 2003-02-28 | Nucleotide mimics and their prodrugs |
AU2003217863A AU2003217863B9 (en) | 2002-02-28 | 2003-02-28 | Nucleotide mimics and their prodrugs |
JP2003571445A JP2005525358A (en) | 2002-02-28 | 2003-02-28 | Nucleotide mimetics and their prodrugs |
EP03713832A EP1485395A4 (en) | 2002-02-28 | 2003-02-28 | Nucleotide mimics and their prodrugs |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US36091502P | 2002-02-28 | 2002-02-28 | |
US36069902P | 2002-02-28 | 2002-02-28 | |
US60/360,699 | 2002-02-28 | ||
US60/360,915 | 2002-02-28 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2003072757A2 WO2003072757A2 (en) | 2003-09-04 |
WO2003072757A3 true WO2003072757A3 (en) | 2004-07-22 |
WO2003072757A9 WO2003072757A9 (en) | 2004-10-21 |
Family
ID=27767599
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2003/006368 WO2003072757A2 (en) | 2002-02-28 | 2003-02-28 | Nucleotide mimics and their prodrugs |
Country Status (7)
Country | Link |
---|---|
US (3) | US7285658B2 (en) |
EP (1) | EP1485395A4 (en) |
JP (1) | JP2005525358A (en) |
AU (1) | AU2003217863B9 (en) |
CA (1) | CA2477741A1 (en) |
RU (1) | RU2004128943A (en) |
WO (1) | WO2003072757A2 (en) |
Families Citing this family (132)
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- 2003-02-28 RU RU2004128943/04A patent/RU2004128943A/en not_active Application Discontinuation
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Also Published As
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US7598230B2 (en) | 2009-10-06 |
RU2004128943A (en) | 2005-04-20 |
WO2003072757A2 (en) | 2003-09-04 |
WO2003072757A9 (en) | 2004-10-21 |
AU2003217863A1 (en) | 2003-09-09 |
JP2005525358A (en) | 2005-08-25 |
AU2003217863B2 (en) | 2009-03-19 |
EP1485395A2 (en) | 2004-12-15 |
US20070265224A1 (en) | 2007-11-15 |
AU2003217863B9 (en) | 2009-10-29 |
US20070259832A1 (en) | 2007-11-08 |
US20040059104A1 (en) | 2004-03-25 |
US7807653B2 (en) | 2010-10-05 |
CA2477741A1 (en) | 2003-09-04 |
EP1485395A4 (en) | 2011-04-13 |
US7285658B2 (en) | 2007-10-23 |
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