WO2003077835A3 - Sodium dodecyl sulfate compositions for inactivating prions - Google Patents

Sodium dodecyl sulfate compositions for inactivating prions Download PDF

Info

Publication number
WO2003077835A3
WO2003077835A3 PCT/US2002/022189 US0222189W WO03077835A3 WO 2003077835 A3 WO2003077835 A3 WO 2003077835A3 US 0222189 W US0222189 W US 0222189W WO 03077835 A3 WO03077835 A3 WO 03077835A3
Authority
WO
WIPO (PCT)
Prior art keywords
sodium dodecyl
dodecyl sulfate
prions
composition
disclosed
Prior art date
Application number
PCT/US2002/022189
Other languages
French (fr)
Other versions
WO2003077835A9 (en
WO2003077835A2 (en
Inventor
Stanley B Prusiner
Surachai Supattapone
Original Assignee
Univ California
Stanley B Prusiner
Surachai Supattapone
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/904,178 external-priority patent/US6719988B2/en
Application filed by Univ California, Stanley B Prusiner, Surachai Supattapone filed Critical Univ California
Priority to EP02807073A priority Critical patent/EP1414297A4/en
Priority to AU2002367715A priority patent/AU2002367715A1/en
Publication of WO2003077835A2 publication Critical patent/WO2003077835A2/en
Publication of WO2003077835A3 publication Critical patent/WO2003077835A3/en
Publication of WO2003077835A9 publication Critical patent/WO2003077835A9/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/30—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests characterised by the surfactants
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N41/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom
    • A01N41/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom containing a sulfur-to-oxygen double bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0088—Liquid substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/02—Anionic compounds
    • C11D1/12—Sulfonic acids or sulfuric acid esters; Salts thereof
    • C11D1/14—Sulfonic acids or sulfuric acid esters; Salts thereof derived from aliphatic hydrocarbons or mono-alcohols
    • C11D1/146—Sulfuric acid esters
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2828—Prion diseases

Abstract

An antiseptic composition useful in destroying the infectivity of infectious proteins such as prions is disclosed. The antiseptic composition is preferably maintained at either a low pH of 4.0 or less or a high pH of 10.0 or more either of which allows for an environment under which the active component (which is preferably sodium dodecyl sulfate) destroys infectivity. The composition may be added to blood, blood products, collagen, tissues and organs prior to transplantation. The composition also may be added to livestock feed to denature any prions in the livestock. Methods of denaturing infectious proteins are also disclosed which method can use but do not require higher temperatures and long period of exposure.
PCT/US2002/022189 2001-07-11 2002-07-11 Sodium dodecyl sulfate compositions for inactivating prions WO2003077835A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP02807073A EP1414297A4 (en) 2001-07-11 2002-07-11 Sodium dodecyl sulfate compositions for inactivating prions
AU2002367715A AU2002367715A1 (en) 2001-07-11 2002-07-11 Sodium dodecyl sulfate compositions for inactivating prions

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US09/904,178 2001-07-11
US09/904,178 US6719988B2 (en) 1997-02-21 2001-07-11 Antiseptic compositions for inactivating prions
US10/056,222 2002-01-22
US10/056,222 US6720355B2 (en) 1997-02-21 2002-01-22 Sodium dodecyl sulfate compositions for inactivating prions

Publications (3)

Publication Number Publication Date
WO2003077835A2 WO2003077835A2 (en) 2003-09-25
WO2003077835A3 true WO2003077835A3 (en) 2004-02-19
WO2003077835A9 WO2003077835A9 (en) 2004-05-21

Family

ID=28044058

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2002/022189 WO2003077835A2 (en) 2001-07-11 2002-07-11 Sodium dodecyl sulfate compositions for inactivating prions

Country Status (4)

Country Link
US (4) US6720355B2 (en)
EP (1) EP1414297A4 (en)
AU (1) AU2002367715A1 (en)
WO (1) WO2003077835A2 (en)

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Also Published As

Publication number Publication date
WO2003077835A9 (en) 2004-05-21
US7226609B2 (en) 2007-06-05
US20030004312A1 (en) 2003-01-02
US20040127558A1 (en) 2004-07-01
EP1414297A4 (en) 2004-09-22
US20040127559A1 (en) 2004-07-01
EP1414297A2 (en) 2004-05-06
US20040052833A1 (en) 2004-03-18
WO2003077835A2 (en) 2003-09-25
US7307103B2 (en) 2007-12-11
AU2002367715A1 (en) 2003-09-29
US6720355B2 (en) 2004-04-13
AU2002367715A8 (en) 2003-09-29

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